TR200003828T2 - Fermentation process to produce clavulanic acid at a low concentration of free amino acids - Google Patents
Fermentation process to produce clavulanic acid at a low concentration of free amino acidsInfo
- Publication number
- TR200003828T2 TR200003828T2 TR2000/03828T TR200003828T TR200003828T2 TR 200003828 T2 TR200003828 T2 TR 200003828T2 TR 2000/03828 T TR2000/03828 T TR 2000/03828T TR 200003828 T TR200003828 T TR 200003828T TR 200003828 T2 TR200003828 T2 TR 200003828T2
- Authority
- TR
- Turkey
- Prior art keywords
- amino acids
- free amino
- low concentration
- fermentation process
- clavulanic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
BIr Streptomyces türünün fermentasyonu ile ikincil metabolitlerin üretimi için gelistirilmis bir yöntem anlatilmistir. Serbest amino asitlerinin konsantrasyonu düsük tutuldugu takdirde, sasirtici ölçüde yüksek bir verim elde edilmektedir.An improved method for the production of secondary metabolites by fermentation of the BIr Streptomyces strain is described. A surprisingly high yield is achieved if the concentration of free amino acids is kept low.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98202264 | 1998-07-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200003828T2 true TR200003828T2 (en) | 2001-06-21 |
Family
ID=8233894
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2000/03828T TR200003828T2 (en) | 1998-07-03 | 1999-07-01 | Fermentation process to produce clavulanic acid at a low concentration of free amino acids |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1097238A1 (en) |
CN (1) | CN1308682A (en) |
AU (1) | AU5409799A (en) |
CA (1) | CA2336363A1 (en) |
MX (1) | MXPA00012930A (en) |
TR (1) | TR200003828T2 (en) |
WO (1) | WO2000001840A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1122305A1 (en) * | 2000-01-31 | 2001-08-08 | Dsm N.V. | Glutamate dehydrogenase-transformed streptomyces clavuligerus with an improved capacity to assimilate ammonia |
WO2009138994A1 (en) * | 2008-05-14 | 2009-11-19 | Biocon Limited | A fermentation process for the production of secondary metabolites |
KR101729251B1 (en) * | 2015-04-28 | 2017-04-21 | 주식회사 대웅 | Medium Composition for Preparing Botulinum Toxin |
KR101723167B1 (en) * | 2015-04-28 | 2017-04-05 | 주식회사 대웅 | Medium Composition for Preparing Botulinum Toxin |
CN105817190B (en) * | 2016-03-15 | 2019-01-08 | 浙江凯色丽科技发展有限公司 | Hydrolyze automatic control system |
CN111944734B (en) * | 2019-05-17 | 2023-01-10 | 中国科学院微生物研究所 | Method for improving yield of streptomycete polyketide |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE41109B1 (en) * | 1974-04-20 | 1979-10-24 | Beecham Group Ltd | Novel -lactam antibiotic from streptomyces clavuligerus |
YU40452B (en) * | 1975-02-07 | 1986-02-28 | Beecham Group Plc | Process for the elimination of contaminating impurities from clavulinic acid |
EP0026044B1 (en) * | 1979-08-24 | 1983-06-08 | Beecham Group Plc | Amine salt of clavulanic acid, its preparation and use |
-
1999
- 1999-07-01 CA CA002336363A patent/CA2336363A1/en not_active Abandoned
- 1999-07-01 MX MXPA00012930A patent/MXPA00012930A/en unknown
- 1999-07-01 EP EP99939986A patent/EP1097238A1/en not_active Withdrawn
- 1999-07-01 TR TR2000/03828T patent/TR200003828T2/en unknown
- 1999-07-01 WO PCT/EP1999/004702 patent/WO2000001840A1/en not_active Application Discontinuation
- 1999-07-01 CN CN 99808223 patent/CN1308682A/en active Pending
- 1999-07-01 AU AU54097/99A patent/AU5409799A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2336363A1 (en) | 2000-01-13 |
MXPA00012930A (en) | 2002-05-08 |
EP1097238A1 (en) | 2001-05-09 |
WO2000001840A1 (en) | 2000-01-13 |
CN1308682A (en) | 2001-08-15 |
AU5409799A (en) | 2000-01-24 |
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