CH624413A5 - - Google Patents

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Publication number
CH624413A5
CH624413A5 CH277580A CH277580A CH624413A5 CH 624413 A5 CH624413 A5 CH 624413A5 CH 277580 A CH277580 A CH 277580A CH 277580 A CH277580 A CH 277580A CH 624413 A5 CH624413 A5 CH 624413A5
Authority
CH
Switzerland
Prior art keywords
group
carbon atoms
formula
erythromycylamine
condensation product
Prior art date
Application number
CH277580A
Other languages
German (de)
English (en)
Inventor
Roland Dr Maier
Eberhard Dr Woitun
Bernd Dr Wetzel
Wolfgang Dr Reuter
Hanns Dr Goeth
Uwe Dr Lechner
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25768725&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH624413(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE2515075A external-priority patent/DE2515075C2/de
Priority claimed from DE19762606030 external-priority patent/DE2606030A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CH624413A5 publication Critical patent/CH624413A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH277580A 1975-04-07 1980-04-10 CH624413A5 (en, 2012)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2515075A DE2515075C2 (de) 1975-04-07 1975-04-07 Erythromycinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE19762606030 DE2606030A1 (de) 1976-02-14 1976-02-14 Neue erythromycinderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
CH624413A5 true CH624413A5 (en, 2012) 1981-07-31

Family

ID=25768725

Family Applications (2)

Application Number Title Priority Date Filing Date
CH417476A CH621800A5 (en, 2012) 1975-04-07 1976-04-02
CH277580A CH624413A5 (en, 2012) 1975-04-07 1980-04-10

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH417476A CH621800A5 (en, 2012) 1975-04-07 1976-04-02

Country Status (29)

Country Link
US (1) US4048306A (en, 2012)
JP (1) JPS51128991A (en, 2012)
AT (1) AT342770B (en, 2012)
AU (1) AU498418B2 (en, 2012)
BG (1) BG27380A3 (en, 2012)
CA (1) CA1060005A (en, 2012)
CH (2) CH621800A5 (en, 2012)
CS (1) CS196304B2 (en, 2012)
DD (1) DD125218A5 (en, 2012)
DK (1) DK138656C (en, 2012)
ES (2) ES446737A1 (en, 2012)
FI (1) FI63244C (en, 2012)
FR (1) FR2306703A1 (en, 2012)
GB (1) GB1520963A (en, 2012)
GR (1) GR60374B (en, 2012)
HU (1) HU175186B (en, 2012)
IE (1) IE43598B1 (en, 2012)
IL (1) IL49359A (en, 2012)
LU (2) LU88563I2 (en, 2012)
MX (1) MX3277E (en, 2012)
NL (1) NL180107C (en, 2012)
NO (1) NO141411C (en, 2012)
NZ (1) NZ180529A (en, 2012)
PL (1) PL101880B1 (en, 2012)
PT (1) PT64977B (en, 2012)
RO (1) RO68441B (en, 2012)
SE (1) SE425566B (en, 2012)
SU (1) SU682134A3 (en, 2012)
YU (1) YU87676A (en, 2012)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847242A (en) 1985-03-12 1989-07-11 Beecham Group P.L.C. 11-ether derivatives of erythromycins
DE3524572A1 (de) * 1985-07-10 1987-01-15 Thomae Gmbh Dr K Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung
US5110800A (en) * 1986-02-18 1992-05-05 Eli Lilly And Company Derivatives of erythromycylamine
US4945080A (en) * 1987-05-26 1990-07-31 Eli Lilly And Company Dirithromycin metabolite
US5075289A (en) * 1988-06-07 1991-12-24 Abbott Laboratories 9-r-azacyclic erythromycin antibiotics
US5403923A (en) * 1990-11-28 1995-04-04 Taisho Pharmaceutical Co., Ltd. 6-0-methylerythromycin A derivatives
ZA922777B (en) * 1991-04-29 1993-10-15 Lilly Co Eli Pharmaceutical formulation containing dirithromycin
US5556839A (en) * 1991-04-29 1996-09-17 Eli Lilly And Company Form II Dirithromycin
ZA927328B (en) * 1991-09-30 1994-03-24 Lilly Co Eli One step process for production of dirithromycin
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
DE4410637C1 (de) * 1994-03-26 1995-09-21 Boehringer Ingelheim Vetmed Injizierbare Lösungen von Dirithromycin
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
WO1999021867A1 (fr) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6541014B2 (en) 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6436906B1 (en) 2001-04-02 2002-08-20 Enanta Pharmaceuticals, Inc. 9-amino-14-membered macrolides derived from leucomycins
EP1648415A4 (en) 2003-07-21 2011-11-16 Middlebrook Pharmaceuticals Inc ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION
JP2006528190A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
AU2004264939A1 (en) 2003-08-11 2005-02-24 Middlebrook Pharmaceuticals, Inc. Robust pellet
WO2005016278A2 (en) 2003-08-12 2005-02-24 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
US8246996B2 (en) * 2003-08-29 2012-08-21 Shionogi Inc. Antibiotic product, use and formulation thereof
CA2538064C (en) 2003-09-15 2013-12-17 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2008505124A (ja) 2004-07-02 2008-02-21 アドバンシス ファーマスーティカル コーポレイション パルス送達用錠剤
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) * 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660376A (en) * 1970-09-30 1972-05-02 Lilly Co Eli N-arylidene erythromycylamines

Also Published As

Publication number Publication date
JPS62158B2 (en, 2012) 1987-01-06
FR2306703B1 (en, 2012) 1979-10-12
GB1520963A (en) 1978-08-09
ES456567A1 (es) 1978-03-01
PT64977A (de) 1976-05-01
NL180107B (nl) 1986-08-01
BG27380A3 (bg) 1979-10-12
HU175186B (hu) 1980-05-28
GR60374B (en) 1978-05-23
DK138656B (da) 1978-10-09
NO141411C (no) 1980-03-05
ATA149976A (de) 1977-08-15
IL49359A0 (en) 1976-06-30
MX3277E (es) 1980-08-15
ES446737A1 (es) 1977-10-16
JPS51128991A (en) 1976-11-10
AU1272276A (en) 1977-10-13
CA1060005A (en) 1979-08-07
US4048306A (en) 1977-09-13
CS196304B2 (en) 1980-03-31
RO68441A (ro) 1983-04-29
DK145276A (da) 1976-10-08
SE425566B (sv) 1982-10-11
PL101880B1 (pl) 1979-02-28
FI63244C (fi) 1983-05-10
FI63244B (fi) 1983-01-31
CH621800A5 (en, 2012) 1981-02-27
PT64977B (de) 1978-04-03
AT342770B (de) 1978-04-25
IL49359A (en) 1979-07-25
SU682134A3 (ru) 1979-08-25
AU498418B2 (en) 1979-03-15
FI760845A7 (en, 2012) 1976-10-08
NZ180529A (en) 1978-09-20
DK138656C (da) 1979-04-02
NO141411B (no) 1979-11-26
DD125218A5 (de) 1977-04-06
LU74702A1 (en, 2012) 1977-06-03
RO68441B (ro) 1983-04-30
FR2306703A1 (fr) 1976-11-05
NL7603569A (nl) 1976-10-11
NO761172L (en, 2012) 1976-10-08
IE43598L (en) 1976-10-07
LU88563I2 (fr) 1995-03-21
SE7604052L (sv) 1976-10-08
IE43598B1 (en) 1981-04-08
NL180107C (nl) 1987-01-02
YU87676A (en) 1982-08-31

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PL Patent ceased