AU498418B2 - Erythromycin derivatives and pharmaceuticals - Google Patents

Erythromycin derivatives and pharmaceuticals

Info

Publication number
AU498418B2
AU498418B2 AU12722/76A AU1272276A AU498418B2 AU 498418 B2 AU498418 B2 AU 498418B2 AU 12722/76 A AU12722/76 A AU 12722/76A AU 1272276 A AU1272276 A AU 1272276A AU 498418 B2 AU498418 B2 AU 498418B2
Authority
AU
Australia
Prior art keywords
pharmaceuticals
erythromycin derivatives
erythromycin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU12722/76A
Other languages
English (en)
Other versions
AU1272276A (en
Inventor
R. Wolton E. Wetzel B. Gueth H. Lechner U. Reuter W Maier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25768725&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU498418(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE2515075A external-priority patent/DE2515075C2/de
Priority claimed from DE19762606030 external-priority patent/DE2606030A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of AU1272276A publication Critical patent/AU1272276A/en
Application granted granted Critical
Publication of AU498418B2 publication Critical patent/AU498418B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU12722/76A 1975-04-07 1976-04-06 Erythromycin derivatives and pharmaceuticals Expired AU498418B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2515075A DE2515075C2 (de) 1975-04-07 1975-04-07 Erythromycinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DEDE82515 1975-04-07
DE19762606030 DE2606030A1 (de) 1976-02-14 1976-02-14 Neue erythromycinderivate und verfahren zu ihrer herstellung
DEDE82606 1976-02-19

Publications (2)

Publication Number Publication Date
AU1272276A AU1272276A (en) 1977-10-13
AU498418B2 true AU498418B2 (en) 1979-03-15

Family

ID=25768725

Family Applications (1)

Application Number Title Priority Date Filing Date
AU12722/76A Expired AU498418B2 (en) 1975-04-07 1976-04-06 Erythromycin derivatives and pharmaceuticals

Country Status (29)

Country Link
US (1) US4048306A (en, 2012)
JP (1) JPS51128991A (en, 2012)
AT (1) AT342770B (en, 2012)
AU (1) AU498418B2 (en, 2012)
BG (1) BG27380A3 (en, 2012)
CA (1) CA1060005A (en, 2012)
CH (2) CH621800A5 (en, 2012)
CS (1) CS196304B2 (en, 2012)
DD (1) DD125218A5 (en, 2012)
DK (1) DK138656C (en, 2012)
ES (2) ES446737A1 (en, 2012)
FI (1) FI63244C (en, 2012)
FR (1) FR2306703A1 (en, 2012)
GB (1) GB1520963A (en, 2012)
GR (1) GR60374B (en, 2012)
HU (1) HU175186B (en, 2012)
IE (1) IE43598B1 (en, 2012)
IL (1) IL49359A (en, 2012)
LU (2) LU88563I2 (en, 2012)
MX (1) MX3277E (en, 2012)
NL (1) NL180107C (en, 2012)
NO (1) NO141411C (en, 2012)
NZ (1) NZ180529A (en, 2012)
PL (1) PL101880B1 (en, 2012)
PT (1) PT64977B (en, 2012)
RO (1) RO68441B (en, 2012)
SE (1) SE425566B (en, 2012)
SU (1) SU682134A3 (en, 2012)
YU (1) YU87676A (en, 2012)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU586262B2 (en) * 1985-07-10 1989-07-06 Dr. Karl Thomae Gmbh Solid pharmaceutical preparation

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847242A (en) 1985-03-12 1989-07-11 Beecham Group P.L.C. 11-ether derivatives of erythromycins
US5110800A (en) * 1986-02-18 1992-05-05 Eli Lilly And Company Derivatives of erythromycylamine
US4945080A (en) * 1987-05-26 1990-07-31 Eli Lilly And Company Dirithromycin metabolite
US5075289A (en) * 1988-06-07 1991-12-24 Abbott Laboratories 9-r-azacyclic erythromycin antibiotics
US5403923A (en) * 1990-11-28 1995-04-04 Taisho Pharmaceutical Co., Ltd. 6-0-methylerythromycin A derivatives
ZA922777B (en) * 1991-04-29 1993-10-15 Lilly Co Eli Pharmaceutical formulation containing dirithromycin
US5556839A (en) * 1991-04-29 1996-09-17 Eli Lilly And Company Form II Dirithromycin
ZA927328B (en) * 1991-09-30 1994-03-24 Lilly Co Eli One step process for production of dirithromycin
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
DE4410637C1 (de) * 1994-03-26 1995-09-21 Boehringer Ingelheim Vetmed Injizierbare Lösungen von Dirithromycin
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
WO1999021867A1 (fr) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6565882B2 (en) 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6541014B2 (en) 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6436906B1 (en) 2001-04-02 2002-08-20 Enanta Pharmaceuticals, Inc. 9-amino-14-membered macrolides derived from leucomycins
EP1648415A4 (en) 2003-07-21 2011-11-16 Middlebrook Pharmaceuticals Inc ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION
JP2006528190A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
AU2004264939A1 (en) 2003-08-11 2005-02-24 Middlebrook Pharmaceuticals, Inc. Robust pellet
WO2005016278A2 (en) 2003-08-12 2005-02-24 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
US8246996B2 (en) * 2003-08-29 2012-08-21 Shionogi Inc. Antibiotic product, use and formulation thereof
CA2538064C (en) 2003-09-15 2013-12-17 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2008505124A (ja) 2004-07-02 2008-02-21 アドバンシス ファーマスーティカル コーポレイション パルス送達用錠剤
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) * 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660376A (en) * 1970-09-30 1972-05-02 Lilly Co Eli N-arylidene erythromycylamines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU586262B2 (en) * 1985-07-10 1989-07-06 Dr. Karl Thomae Gmbh Solid pharmaceutical preparation

Also Published As

Publication number Publication date
JPS62158B2 (en, 2012) 1987-01-06
FR2306703B1 (en, 2012) 1979-10-12
GB1520963A (en) 1978-08-09
ES456567A1 (es) 1978-03-01
PT64977A (de) 1976-05-01
NL180107B (nl) 1986-08-01
BG27380A3 (bg) 1979-10-12
HU175186B (hu) 1980-05-28
GR60374B (en) 1978-05-23
DK138656B (da) 1978-10-09
NO141411C (no) 1980-03-05
ATA149976A (de) 1977-08-15
IL49359A0 (en) 1976-06-30
MX3277E (es) 1980-08-15
ES446737A1 (es) 1977-10-16
JPS51128991A (en) 1976-11-10
AU1272276A (en) 1977-10-13
CA1060005A (en) 1979-08-07
US4048306A (en) 1977-09-13
CS196304B2 (en) 1980-03-31
RO68441A (ro) 1983-04-29
DK145276A (da) 1976-10-08
SE425566B (sv) 1982-10-11
PL101880B1 (pl) 1979-02-28
FI63244C (fi) 1983-05-10
FI63244B (fi) 1983-01-31
CH621800A5 (en, 2012) 1981-02-27
PT64977B (de) 1978-04-03
AT342770B (de) 1978-04-25
IL49359A (en) 1979-07-25
SU682134A3 (ru) 1979-08-25
FI760845A7 (en, 2012) 1976-10-08
NZ180529A (en) 1978-09-20
DK138656C (da) 1979-04-02
NO141411B (no) 1979-11-26
DD125218A5 (de) 1977-04-06
LU74702A1 (en, 2012) 1977-06-03
RO68441B (ro) 1983-04-30
FR2306703A1 (fr) 1976-11-05
NL7603569A (nl) 1976-10-11
NO761172L (en, 2012) 1976-10-08
IE43598L (en) 1976-10-07
LU88563I2 (fr) 1995-03-21
SE7604052L (sv) 1976-10-08
CH624413A5 (en, 2012) 1981-07-31
IE43598B1 (en) 1981-04-08
NL180107C (nl) 1987-01-02
YU87676A (en) 1982-08-31

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