CH618686A5 - - Google Patents
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- Publication number
- CH618686A5 CH618686A5 CH831576A CH831576A CH618686A5 CH 618686 A5 CH618686 A5 CH 618686A5 CH 831576 A CH831576 A CH 831576A CH 831576 A CH831576 A CH 831576A CH 618686 A5 CH618686 A5 CH 618686A5
- Authority
- CH
- Switzerland
- Prior art keywords
- lofepramine
- hydrochloride
- acetate
- solvent
- propyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB28145/75A GB1497306A (en) | 1975-07-03 | 1975-07-03 | Preparation of lofepramine and its hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH618686A5 true CH618686A5 (el) | 1980-08-15 |
Family
ID=10270996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH831576A CH618686A5 (el) | 1975-07-03 | 1976-06-29 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4172074A (el) |
| JP (1) | JPS6014030B2 (el) |
| BE (1) | BE843691A (el) |
| CA (1) | CA1079274A (el) |
| CH (1) | CH618686A5 (el) |
| DE (1) | DE2628558A1 (el) |
| FR (1) | FR2316234A1 (el) |
| GB (1) | GB1497306A (el) |
| IE (1) | IE43255B1 (el) |
| SE (1) | SE7607565L (el) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4108119A1 (de) * | 1991-03-13 | 1992-09-17 | Jellalabad Ltd | Verfahren zur herstellung von 4'-chlor-2-((3-(10,11-dihydro-5h-dibenz(b,f)azepin-5-yl)propyl) methylaminno) acetophenon und seiner salze, die stabilisierungseiner salze, hierbei erhaeltliche produkte und pharmmazeutische zubereitungen, die diese enthalten |
| EP0784476B1 (en) * | 1994-10-05 | 2002-11-06 | Cari Loder | Treatment of multiple sclerosis (ms) and other demyelinating conditions using lofepramine in combination with l-phenylalanine, tyrosine or tryptophan and optionally a vitamin b 12 compound |
| GB2308065B (en) * | 1994-10-05 | 1999-01-13 | Cari Loder | Treatment of multiple sclerosis (MS) and other demyelinating conditions |
| CA2548917C (en) | 2003-12-11 | 2014-09-23 | Sepracor Inc. | Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression |
| AU2005290980A1 (en) * | 2004-10-01 | 2006-04-13 | Neurocure Ltd | Use of pharmaceutical compositions of lofepramine for the treatment of ADHD, CFS, FM and depression |
| CA2614289A1 (en) * | 2005-07-08 | 2007-01-18 | Braincells, Inc. | Methods for identifying agents and conditions that modulate neurogenesis |
| US20070112017A1 (en) | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| MX2008014320A (es) | 2006-05-09 | 2009-03-25 | Braincells Inc | Neurogenesis mediada por el receptor de 5-hidroxitriptamina. |
| US7858611B2 (en) * | 2006-05-09 | 2010-12-28 | Braincells Inc. | Neurogenesis by modulating angiotensin |
| AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| WO2008083204A2 (en) * | 2006-12-28 | 2008-07-10 | Braincells, Inc. | Modulation of neurogenesis by melatoninergic ligands |
| AU2008204800A1 (en) * | 2007-01-11 | 2008-07-17 | Braincells, Inc. | Modulation of neurogenesis with use of modafinil |
| US20110034565A1 (en) | 2008-04-18 | 2011-02-10 | University College Dublin, National University Of Ireland, Dublin | Psycho-pharmaceuticals |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1177525A (en) * | 1967-04-13 | 1970-01-14 | Leo Ab | New Heterocyclic Aminoketones of Therapeutic Interest |
-
1975
- 1975-07-03 GB GB28145/75A patent/GB1497306A/en not_active Expired
-
1976
- 1976-06-21 US US05/697,764 patent/US4172074A/en not_active Expired - Lifetime
- 1976-06-23 CA CA255,508A patent/CA1079274A/en not_active Expired
- 1976-06-25 DE DE19762628558 patent/DE2628558A1/de active Granted
- 1976-06-29 CH CH831576A patent/CH618686A5/de not_active IP Right Cessation
- 1976-07-01 BE BE168562A patent/BE843691A/xx not_active IP Right Cessation
- 1976-07-01 SE SE7607565A patent/SE7607565L/xx unknown
- 1976-07-01 FR FR7620102A patent/FR2316234A1/fr active Granted
- 1976-07-02 IE IE1469/76A patent/IE43255B1/en unknown
- 1976-07-03 JP JP51078518A patent/JPS6014030B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE7607565L (sv) | 1977-01-04 |
| BE843691A (fr) | 1977-01-03 |
| DE2628558A1 (de) | 1977-01-20 |
| DE2628558C2 (el) | 1989-11-16 |
| FR2316234B1 (el) | 1979-06-08 |
| GB1497306A (en) | 1978-01-05 |
| CA1079274A (en) | 1980-06-10 |
| IE43255B1 (en) | 1981-01-14 |
| JPS527982A (en) | 1977-01-21 |
| US4172074A (en) | 1979-10-23 |
| FR2316234A1 (fr) | 1977-01-28 |
| IE43255L (en) | 1977-01-03 |
| JPS6014030B2 (ja) | 1985-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PFA | Name/firm changed |
Owner name: PHARMACIA BIOSYSTEMS AB |
|
| PUE | Assignment |
Owner name: PHARMACIA AKTIEBOLAG |
|
| PL | Patent ceased |