CH618164A5 - Process for the preparation of novel 1-(2',4',6'-trihydroxphenyl)-1,2-propanedione compounds substituted in the 3-position - Google Patents

Process for the preparation of novel 1-(2',4',6'-trihydroxphenyl)-1,2-propanedione compounds substituted in the 3-position Download PDF

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Publication number
CH618164A5
CH618164A5 CH771375A CH771375A CH618164A5 CH 618164 A5 CH618164 A5 CH 618164A5 CH 771375 A CH771375 A CH 771375A CH 771375 A CH771375 A CH 771375A CH 618164 A5 CH618164 A5 CH 618164A5
Authority
CH
Switzerland
Prior art keywords
compound
formula
compounds
och
hours
Prior art date
Application number
CH771375A
Other languages
German (de)
English (en)
Inventor
Rolf Dr Med Madaus
Guenter Dr Rer Nat Halbach
Vet Wilfried Dr Med Trost
Original Assignee
Madaus & Co Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Madaus & Co Dr filed Critical Madaus & Co Dr
Publication of CH618164A5 publication Critical patent/CH618164A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/201,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH771375A 1974-06-14 1975-06-13 Process for the preparation of novel 1-(2',4',6'-trihydroxphenyl)-1,2-propanedione compounds substituted in the 3-position CH618164A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2428680A DE2428680C2 (de) 1974-06-14 1974-06-14 1-(2',4',6'-Trihydroxyphenyl)-propandion-(1,2)-Verbindungen, Verfahren zu deren Herstellung und Arzneimittel, die diese Verbindungen enthalten

Publications (1)

Publication Number Publication Date
CH618164A5 true CH618164A5 (en) 1980-07-15

Family

ID=5918092

Family Applications (1)

Application Number Title Priority Date Filing Date
CH771375A CH618164A5 (en) 1974-06-14 1975-06-13 Process for the preparation of novel 1-(2',4',6'-trihydroxphenyl)-1,2-propanedione compounds substituted in the 3-position

Country Status (15)

Country Link
US (1) US4168318A (fi)
JP (1) JPS5111755A (fi)
AT (1) AT348521B (fi)
BE (1) BE830154A (fi)
CA (1) CA1049021A (fi)
CH (1) CH618164A5 (fi)
DE (1) DE2428680C2 (fi)
ES (1) ES438537A1 (fi)
FI (1) FI63755C (fi)
FR (1) FR2274297A1 (fi)
GB (1) GB1504758A (fi)
IT (1) IT1054625B (fi)
NL (1) NL7506998A (fi)
SE (1) SE418400B (fi)
ZA (1) ZA753829B (fi)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2840467A1 (de) * 1978-09-16 1980-03-20 Madaus & Co Dr 3,4-dihydroxizimtaldehydderivat, dessen herstellung und arzneimittel
AU3444099A (en) * 1998-04-29 1999-11-16 Choongwae Pharmaceutical Co., Ltd. Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases
US6693126B2 (en) 2000-10-27 2004-02-17 Choongwae Pharm. Co., Ltd. Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB966866A (en) * 1960-12-13 1964-08-19 Angeli Inst Spa 2-benzodioxan-methyl hydrazines and their hydrazones
US3117978A (en) * 1961-01-25 1964-01-14 Lakeside Lab Inc 1, 4-benzodioxane-2-carboxamides
DE1518042C3 (de) * 1965-11-11 1975-04-10 Merck Patent Gmbh, 6100 Darmstadt 1,4-Benzodioxanderivate und Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
DE1923082C3 (de) * 1969-05-06 1985-08-22 Dr. Madaus & Co, 5000 Koeln Verfahren zur Gewinnung von Polyhydroxyphenylchromanonen (Silymarin I-IV) und Arzneimittel enthaltend das Polyhydroxyphenylchromanon (Silymarin I-IV = Silymarin I-IV-Gruppe)Gemisch
GB1307390A (en) * 1970-09-24 1973-02-21 Ward Blenkinsop & Co Ltd Benzodioxanes

Also Published As

Publication number Publication date
ZA753829B (en) 1976-06-30
US4168318A (en) 1979-09-18
CA1049021A (en) 1979-02-20
SE418400B (sv) 1981-05-25
FI751575A (fi) 1975-12-15
FR2274297B1 (fi) 1983-02-18
NL7506998A (nl) 1975-12-16
IT1054625B (it) 1981-11-30
BE830154A (fr) 1975-12-12
SE7506729L (sv) 1975-12-15
FR2274297A1 (fr) 1976-01-09
FI63755B (fi) 1983-04-29
AT348521B (de) 1979-02-26
FI63755C (fi) 1983-08-10
DE2428680A1 (de) 1976-01-02
JPS5111755A (en) 1976-01-30
ATA458875A (de) 1978-07-15
ES438537A1 (es) 1977-01-16
JPS5538948B2 (fi) 1980-10-07
DE2428680C2 (de) 1983-02-17
GB1504758A (en) 1978-03-22

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Legal Events

Date Code Title Description
PFA Name/firm changed

Owner name: DR. MADAUS GMBH & CO.

PUE Assignment

Owner name: MADAUS AG

PL Patent ceased