CH558362A - Verfahren zur herstellung von endoaethano-tetrahydrothebainen bzw. -oripavinen. - Google Patents

Verfahren zur herstellung von endoaethano-tetrahydrothebainen bzw. -oripavinen.

Info

Publication number
CH558362A
CH558362A CH861766A CH861766A CH558362A CH 558362 A CH558362 A CH 558362A CH 861766 A CH861766 A CH 861766A CH 861766 A CH861766 A CH 861766A CH 558362 A CH558362 A CH 558362A
Authority
CH
Switzerland
Prior art keywords
sep
endoethano
hydroxy
formula
propyl
Prior art date
Application number
CH861766A
Other languages
German (de)
English (en)
Original Assignee
Reckitt & Colmann Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt & Colmann Prod Ltd filed Critical Reckitt & Colmann Prod Ltd
Priority to CH359670A priority Critical patent/CH551415A/de
Publication of CH558362A publication Critical patent/CH558362A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
    • C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
    • C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH861766A 1965-06-15 1966-06-15 Verfahren zur herstellung von endoaethano-tetrahydrothebainen bzw. -oripavinen. CH558362A (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH359670A CH551415A (de) 1965-06-15 1966-06-15 Verfahren zur herstellung von heterocyclischen verbindungen.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB25289/65A GB1136214A (en) 1965-06-15 1965-06-15 Thebaine and oripavine derivatives

Publications (1)

Publication Number Publication Date
CH558362A true CH558362A (de) 1975-01-31

Family

ID=10225305

Family Applications (1)

Application Number Title Priority Date Filing Date
CH861766A CH558362A (de) 1965-06-15 1966-06-15 Verfahren zur herstellung von endoaethano-tetrahydrothebainen bzw. -oripavinen.

Country Status (14)

Country Link
AT (1) AT272530B (no)
BE (1) BE682551A (no)
BR (1) BR6680359D0 (no)
CH (1) CH558362A (no)
DE (1) DE1620206A1 (no)
DK (1) DK115926B (no)
ES (1) ES327925A1 (no)
FI (1) FI49724C (no)
FR (1) FR6395M (no)
GB (1) GB1136214A (no)
LU (1) LU51306A1 (no)
NL (1) NL6608255A (no)
NO (1) NO119590B (no)
SE (1) SE325276B (no)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003095458A1 (en) * 2002-05-10 2003-11-20 Reckitt Benckiser Healthcare (Uk) Limited Microbial n- and o-demethylation of a thebaine derivative

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2554816B1 (fr) * 1983-11-16 1986-09-26 Sanofi Sa Nouveau derive de la nororipavine presentant a la fois une activite agoniste et antagoniste des recepteurs morphiniques
KR100204659B1 (ko) * 1996-05-28 1999-06-15 강재헌 신규한 부프레노핀계 진통제용 화합물
AUPQ968300A0 (en) 2000-08-25 2000-09-21 Glaxo Wellcome Australia Ltd Chemical methods
GB0421687D0 (en) † 2004-09-30 2004-11-03 Johnson Matthey Plc Preparation of opiate analgesics
CA2614223A1 (en) 2005-02-24 2006-08-31 Dr Pharma Nova, Llc A registry method and control system for dea schedule ii-v medicines
DE102006054731B4 (de) 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
CN103450206A (zh) * 2008-07-30 2013-12-18 普渡制药公司 丁丙诺啡类似物
EP2342207B1 (en) 2008-09-30 2015-11-11 Mallinckrodt LLC Processes for the alkylation of norbuprenorphine with reduced impurity formation
WO2010121369A1 (en) 2009-04-24 2010-10-28 Brock University Processes for the preparation of morphinane and morphinone compounds
GB201111775D0 (en) 2011-07-08 2011-08-24 Univ Bath Compounds and uses thereof
MX352795B (es) 2011-12-12 2017-12-07 Lts Lohmann Therapie Systeme Ag Sistema de administracion transdermica que comprende buprenorfina.
EP2877155B1 (en) 2012-07-26 2020-10-28 Camurus AB Opioid formulations
EP2931729B1 (en) * 2012-12-07 2019-02-06 Purdue Pharma LP Buprenorphine analogs as opiod receptor modulators
GB2529789A (en) 2013-06-04 2016-03-02 Lohmann Therapie Syst Lts Transdermal Delivery system
CA3238849A1 (en) 2021-12-16 2023-06-22 Arevipharma Gmbh Method of making buprenorphine and precursor compounds thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003095458A1 (en) * 2002-05-10 2003-11-20 Reckitt Benckiser Healthcare (Uk) Limited Microbial n- and o-demethylation of a thebaine derivative
US7267968B2 (en) 2002-05-10 2007-09-11 Reckitt Benekiser Healthcare (Uk) Limited Microbial n-and o-demethylation of a thebaine derivative

Also Published As

Publication number Publication date
FR6395M (no) 1968-10-21
SE325276B (no) 1970-06-29
BR6680359D0 (pt) 1973-12-26
AT272530B (de) 1969-07-10
LU51306A1 (no) 1966-08-16
DK115926B (da) 1969-11-24
NO119590B (no) 1970-06-08
FI49724B (no) 1975-06-02
DE1620206A1 (de) 1970-03-19
ES327925A1 (es) 1967-04-01
NL6608255A (no) 1966-12-16
GB1136214A (en) 1968-12-11
FI49724C (fi) 1975-09-10
BE682551A (no) 1966-11-14

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