CA3010505A1 - Methods for improving milk production by administration of microbial consortia - Google Patents

Methods for improving milk production by administration of microbial consortia Download PDF

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Publication number
CA3010505A1
CA3010505A1 CA3010505A CA3010505A CA3010505A1 CA 3010505 A1 CA3010505 A1 CA 3010505A1 CA 3010505 A CA3010505 A CA 3010505A CA 3010505 A CA3010505 A CA 3010505A CA 3010505 A1 CA3010505 A1 CA 3010505A1
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CA
Canada
Prior art keywords
ascusb
composition
increase
microbial
milk
Prior art date
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Pending
Application number
CA3010505A
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English (en)
French (fr)
Inventor
Mallory EMBREE
Luke PICKING
Grant GOGUL
Janna TARASOVA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Native Microbials Inc
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Ascus Biosciences Inc
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Application filed by Ascus Biosciences Inc filed Critical Ascus Biosciences Inc
Publication of CA3010505A1 publication Critical patent/CA3010505A1/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/37Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/28Silicates, e.g. perlites, zeolites or bentonites
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K40/00Shaping or working-up of animal feeding-stuffs
    • A23K40/30Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • A23K40/35Making capsules specially adapted for ruminants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/10Feeding-stuffs specially adapted for particular animals for ruminants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L31/00Edible extracts or preparations of fungi; Preparation or treatment thereof
    • A23L31/10Yeasts or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/064Saccharomycetales, e.g. baker's yeast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/748Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Animal Husbandry (AREA)
  • Molecular Biology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Birds (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
CA3010505A 2016-01-07 2017-01-06 Methods for improving milk production by administration of microbial consortia Pending CA3010505A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201662276142P 2016-01-07 2016-01-07
US62/276,142 2016-01-07
US201662276531P 2016-01-08 2016-01-08
US62/276,531 2016-01-08
US201662334816P 2016-05-11 2016-05-11
US62/334,816 2016-05-11
US201662415908P 2016-11-01 2016-11-01
US62/415,908 2016-11-01
PCT/US2017/012573 WO2017120495A1 (en) 2016-01-07 2017-01-06 Methods for improving milk production by administration of microbial consortia

Publications (1)

Publication Number Publication Date
CA3010505A1 true CA3010505A1 (en) 2017-07-13

Family

ID=59274021

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3010505A Pending CA3010505A1 (en) 2016-01-07 2017-01-06 Methods for improving milk production by administration of microbial consortia

Country Status (12)

Country Link
US (13) US9993507B2 (enExample)
EP (1) EP3400285B1 (enExample)
JP (2) JP7082058B2 (enExample)
CN (1) CN109757107A (enExample)
AU (2) AU2017206051B2 (enExample)
CA (1) CA3010505A1 (enExample)
CL (1) CL2018001846A1 (enExample)
MX (2) MX392304B (enExample)
NZ (1) NZ743958A (enExample)
RU (1) RU2018128578A (enExample)
UY (1) UY37069A (enExample)
WO (1) WO2017120495A1 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014141274A1 (en) 2013-03-14 2014-09-18 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Microbial compositions comprising rumen microflora and uses thereof
US10851399B2 (en) 2015-06-25 2020-12-01 Native Microbials, Inc. Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
MX388995B (es) 2015-06-25 2025-03-20 Native Microbials Inc Métodos, aparatos y sistemas para analizar cepas de microorganismos de comunidades heterogéneas complejas, predecir e indentificar sus relaciones funcionales e interacciones y seleccionar y sintetizar conjuntos microbianos basados en estos.
US9938558B2 (en) 2015-06-25 2018-04-10 Ascus Biosciences, Inc. Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
NZ743958A (en) 2016-01-07 2023-07-28 Native Microbials Inc Methods for improving milk production by administration of microbial consortia
BR122022006025B1 (pt) 2016-04-26 2023-05-16 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Método para determinar eficiência alimentar ou produção de metano de animal ruminante
US11015154B2 (en) * 2016-11-09 2021-05-25 The Regents Of The University Of California Methods for identifying interactions amongst microorganisms
CN110352250A (zh) 2016-12-28 2019-10-18 埃斯库斯生物科技股份公司 用于通过示踪剂分析法对复杂异质群落进行微生物株系分析、确定其功能关系及相互作用以及合成包括给药微生物群集和接种微生物群集的微生物群集的方法、设备和系统
AU2017386658A1 (en) 2016-12-28 2019-07-25 Native Microbials, Inc. Methods, apparatuses, and systems for analyzing complete microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and identifying and synthesizing bioreactive modificators based thereon
WO2018201049A1 (en) 2017-04-28 2018-11-01 Ascus Biosciences, Inc. Methods for supporting grain intensive and/or energy intensive diets in ruminants with a synthetic bioensemble of microbes
WO2018217764A1 (en) * 2017-05-22 2018-11-29 Kansas State University Research Foundation Microbiome transplantation
CN107389656A (zh) * 2017-07-31 2017-11-24 江南大学 拉曼光谱表征反复冻融过程中牛肉脂肪品质变化的方法
US11066929B2 (en) * 2017-08-15 2021-07-20 Saudi Arabian Oil Company Identifying oil and gas reservoirs with oxygen isotopes
EP3453395B1 (en) * 2017-09-08 2023-10-18 Deutsches Rheuma-Forschungszentrum Berlin Anaeroplasmatales for use in the treatment or prevention of an inflammatory disorder of the digestive system
KR102061738B1 (ko) 2018-04-30 2020-01-02 이성재 깻묵을 이용하는 배합사료의 제조방법
US11242544B2 (en) * 2018-07-11 2022-02-08 Wisconsin Alumni Research Foundation Microbiomes and methods for producing medium-chain fatty acids from organic substrates
EP3757594B1 (en) * 2018-11-02 2022-08-17 LG Energy Solution, Ltd. Current sensor diagnosing apparatus and method
CN111317032A (zh) * 2018-12-14 2020-06-23 内蒙古蒙牛乳业(集团)股份有限公司 液态乳制品及其制备方法
EP3931300A4 (en) * 2019-02-28 2022-11-23 Native Microbials, Inc. METHODS, DEVICES AND SYSTEMS FOR IMPROVING YIELD IN MICROBIAL PRESERVATION BY RESCUE AND SERIAL PASSAGE OF PRESERVED CELLS
US11427865B2 (en) * 2019-07-12 2022-08-30 California Institute Of Technology Absolute quantification of nucleic acids and related methods and systems
US12173361B2 (en) * 2019-07-12 2024-12-24 California Institute Of Technology Rodent model and related device, compositions, methods and systems
WO2021011662A2 (en) * 2019-07-15 2021-01-21 Native Micro Bials, Inc. Compositions and methods for broiler health and performance
MX2022000802A (es) 2019-07-30 2022-02-16 Kobiolabs Inc Kit para predecir o diagnosticar enfermedad de higado graso no alcoholico, y metodo para diagnosticar enfermedad de higado graso no alcoholico.
CN110628862A (zh) * 2019-09-24 2019-12-31 哈尔滨工业大学 一种废水梯级能源回收的自聚集颗粒污泥构建方法
CN110846246A (zh) * 2019-11-06 2020-02-28 广东省生物资源应用研究所 一种具有氨氮降解功能的细菌初步筛选方法
WO2021138571A1 (en) * 2019-12-31 2021-07-08 Assembly Biosciences, Inc. Compositions comprising bacterial species and methods related thereto
US20230138227A1 (en) * 2020-02-25 2023-05-04 Karoll Andriettee GONZALEZ PIZARRO Group of microorganisms composed by lactobacillus sp strain k03d08, bacillus sp strain k03b01 and kazachstania sp strain k03k02g and its compositions; a process for obtaining casein-free dairy derivative containing short-chain fatty acids and hydroxylated short-chain fatty acids generated by the metabolism of the group of microorganisms
WO2021202804A1 (en) * 2020-03-31 2021-10-07 Native Microbials, Inc. Improving milk production and compositional characteristics with novel ruminococcus bovis
CA3201057A1 (en) 2020-12-08 2022-06-16 Mark Christopher LAY Improvements to devices and methods for delivery of substances to animals
CN112458025B (zh) * 2020-12-15 2023-06-20 上海海洋大学 一株深海亚硫酸杆菌在诱导厚壳贻贝稚贝附着中的应用
US20220240542A1 (en) * 2021-01-29 2022-08-04 Zivo Bioscience, Inc. Maturation of immune and metabolic processes via algal biomass and/or related material administered to animals
AR125444A1 (es) * 2021-04-22 2023-07-19 Native Microbials Inc Composiciones y métodos para mejorar el rendimiento lácteo y las características composicionales de los lácteos en rumiantes
US20240269205A1 (en) * 2021-06-07 2024-08-15 Farida Hanna Campbell Multi-virus anti-infectivity and pro-immunity assembly
CN113493752B (zh) * 2021-07-15 2022-05-06 长江大学 一株铁还原菌Tessaracoccus oleiagri DH10菌株及其应用
EP4380374A4 (en) 2021-07-30 2025-01-01 Loam Bio Pty Ltd METHOD FOR REDUCING METHANE PRODUCTION IN RUMINANTS
US20240226045A9 (en) * 2022-10-25 2024-07-11 Balchem Corporation Rumen-protected compositions and methods of making the same
AU2023372349B2 (en) 2022-11-02 2025-07-03 Ruminant Biotech Corp Limited Devices and methods for delivering methane inhibiting compounds to animals
WO2024173808A1 (en) * 2023-02-17 2024-08-22 Duke University Microbiome-derived compositions and methods for the prevention and treatment of viral infections
WO2024229172A2 (en) * 2023-05-01 2024-11-07 Native Microbials, Inc. Compositions and methods for reducing enteric methane emission in ruminants
WO2025184454A1 (en) * 2024-02-28 2025-09-04 Raison, Llc Microbial compositions and methods for improving ruminant digestion
CN118374388B (zh) * 2024-04-11 2024-11-01 中国农业科学院饲料研究所 一株发酵氨基酸球菌及其改善瘤胃发酵的应用
CN119432677B (zh) * 2024-12-19 2025-05-27 西北农林科技大学 一株能够提高反刍动物产奶量及乳脂率的布氏普氏菌b14及其应用
CN119736409B (zh) * 2024-12-31 2025-11-28 西北农林科技大学 一种与反刍动物的泌乳性能相关的瘤胃微生物标志物及其应用
CN120449457B (zh) * 2025-04-25 2025-11-07 华北电力大学 捕食强化梯级固定生物膜污水处理工艺双环境-三组分耦合方法

Family Cites Families (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3484243A (en) 1966-07-07 1969-12-16 Feed Service Corp Liquid animal feed compositions and process for preparing same
SE441009B (sv) 1982-03-08 1985-09-02 Kjell Nilsson Sett att immobilisera levande biomaterial i perlformiga polymerer
US4559298A (en) 1982-11-23 1985-12-17 American National Red Cross Cryopreservation of biological materials in a non-frozen or vitreous state
FI84874C (fi) 1989-11-02 1992-02-10 Valio Meijerien Foerfarande foer inkapsling av biologiskt aktiva aemnen, enligt metoden framstaelld kapsel, dess anvaendning och foder innehaollande den.
US5200399A (en) 1990-09-14 1993-04-06 Boyce Thompson Institute For Plant Research, Inc. Method of protecting biological materials from destructive reactions in the dry state
US5292523A (en) 1991-12-11 1994-03-08 Nippon Kayaku Kabushiki Kaisha Method for growth promotion of animals and powder compositions containing killed microbial cells of bacteria belonging to genus clostridium
NZ253866A (en) * 1992-06-16 1997-05-26 Stolle Res & Dev The use of hyperimmune milk to retard or delay physiological aging and increase longevity
JP2917818B2 (ja) 1993-07-21 1999-07-12 鐘淵化学工業株式会社 家畜類又は家禽類から得られる肉又は脂肪の鮮度保持力を増大させる方法
JP4074659B2 (ja) 1993-08-06 2008-04-09 バイオテック エイエスエイ 酵母菌グルカンを含有する動物飼料
US5733568A (en) 1993-12-03 1998-03-31 Lafor Laboratories Limited Micro-encapsulated lactobacilli for medical applications
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5534271A (en) 1994-11-16 1996-07-09 Nutrition Physiology Process for improving the utilization of feedstuffs by ruminants
US6214337B1 (en) 1995-04-18 2001-04-10 Biotec Asa Animal feeds comprising yeast glucan
US20050158699A1 (en) 1995-06-07 2005-07-21 Kadkade Prakash G. Cryopreservation of plant cells
US5900262A (en) 1995-09-20 1999-05-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Fermented formula feed, its production, and uses
GB9620209D0 (en) 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
US5776753A (en) 1997-06-11 1998-07-07 Incyte Pharmaceuticals, Inc. Human peroxisomal thioesterase
AU753327B2 (en) 1997-07-11 2002-10-17 Dragon Pacific Limited Methods and probiotics for improving starch utilisation and preventing over-production of acid in the rumen or gut of animals
GB9914412D0 (en) 1999-06-22 1999-08-18 Worrall Eric E Method for the preservation of viruses,bacteria and biomolecules
US6440447B1 (en) 1999-06-22 2002-08-27 Land O'lakes, Inc. Method and composition for enhancing milk production
CA2382061A1 (en) 1999-08-19 2001-02-22 Victor Bronshtein Preservation of bacterial cells at ambient temperatures
US6274320B1 (en) 1999-09-16 2001-08-14 Curagen Corporation Method of sequencing a nucleic acid
US6613520B2 (en) 2000-04-10 2003-09-02 Matthew Ashby Methods for the survey and genetic analysis of populations
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
JP2005508647A (ja) 2001-11-12 2005-04-07 マーズ インコーポレイテッド 食品
US7427408B2 (en) 2002-06-06 2008-09-23 The Regents Of The University Of California Quorum sensing and biofilm formation
CA2492805C (en) 2002-07-18 2015-05-12 Agricultural Research Council Megasphaera elsdenii strain and its uses
US7488503B1 (en) 2003-03-31 2009-02-10 Mccormick & Company, Inc. Encapsulation compositions and processes for preparing the same
US20050239706A1 (en) 2003-10-31 2005-10-27 Washington University In St. Louis Modulation of fiaf and the gastrointestinal microbiota as a means to control energy storage in a subject
WO2005052138A1 (en) 2003-11-19 2005-06-09 Wisconsin Alumni Research Foundation Cryopreservation of pluripotent stem cells
US8110214B2 (en) 2003-12-23 2012-02-07 Land O'lakes Purina Feed Llc Method and composition for enhancing milk production and milk component concentrations
US7750890B2 (en) 2004-05-11 2010-07-06 The Chamberlain Group, Inc. Movable barrier operator system display method and apparatus
CN1298236C (zh) * 2004-05-25 2007-02-07 中国农业大学 小肽与有益微生物合生元饲料添加剂及其用途
EP2567708A3 (en) 2004-06-02 2013-10-16 Victor Bronshtein Preservation by vaporization
US20060127530A1 (en) 2004-12-10 2006-06-15 Axelrod Glen S Avian feed
DE102005020457A1 (de) * 2005-04-29 2006-11-02 Westfaliasurge Gmbh Verwendung nicht-pathogener, sporenbildender Bakterien
BRPI0611492B1 (pt) 2005-05-31 2021-10-13 Mars, Incorporated Bifidobactéria probiótica felina
JP5214464B2 (ja) * 2005-12-28 2013-06-19 アドバンスド バイオニュートリション コーポレーション 多糖類、糖類およびポリオール類の乾燥マトリックスを含む、ガラス形態の、プロバイオティクス細菌用送達媒体およびその製造方法
CN101415342B (zh) 2006-03-31 2013-07-17 日本制纸化学株式会社 饮食用组合物
WO2008076975A1 (en) 2006-12-18 2008-06-26 Advanced Bionutrition Corporation A dry food product containing live probiotic
US20080299098A1 (en) 2007-04-24 2008-12-04 Chea-Yun Se Broad-Spectrum Antibacterial and Antifungal Activity of Lactobacillus Johnsonii D115
US8349252B2 (en) 2007-06-27 2013-01-08 University Of North Carolina At Charlotte Vitrified composition which preserves biological materials
CN101519638B (zh) * 2008-02-27 2011-05-18 中国科学院微生物研究所 一种生产酒精的方法及其专用克鲁斯假丝酵母菌株
PL2105129T3 (pl) 2008-03-24 2018-04-30 Intervet International B.V. Szczepionki w kapsułkach do szczepienia doustnego i wzmocnienia dla ryb i innych zwierząt
WO2010015580A1 (en) 2008-08-04 2010-02-11 Dsm Ip Assets B.V. Production of beadlets comprising probiotic compounds
JP5410708B2 (ja) 2008-08-11 2014-02-05 クロスフィールドバイオ株式会社 新属シャーペア(Sharpea)属に属する微生物および微生物製剤並びに経口組成物
US9803250B2 (en) 2008-11-26 2017-10-31 Fred Hutchinson Cancer Research Center Broad range PCR-based compositions and methods for the detection and identification of fungal pathogens
ES2732833T3 (es) 2009-03-26 2019-11-26 Advanced Bionutrition Corp Microencapsulación de sustancias bioactivas y métodos de obtención de la misma
CA2986751A1 (en) 2009-03-27 2010-09-30 Intervet International B.V. Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish
AU2010254235B2 (en) 2009-05-26 2015-04-02 Advanced Bionutrition Corporation Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making
KR101255050B1 (ko) 2009-07-14 2013-04-16 씨제이제일제당 (주) 신규한 락토바실러스 플란타룸 및 이를 포함하는 조성물
WO2011022660A1 (en) 2009-08-21 2011-02-24 Puretech Ventures, Llc Methods of diagnosing and treating microbiome-associated disease using interaction network parameters
US8449916B1 (en) 2009-11-06 2013-05-28 Iowa State University Research Foundation, Inc. Antimicrobial compositions and methods
CN102651973A (zh) 2009-12-18 2012-08-29 希尔氏宠物营养品公司 包含益生菌的宠物食物组合物及其制造和使用方法
CA2785815C (en) 2010-01-28 2018-04-24 Advanced Bionutrition Corporation Dry glassy composition comprising a bioactive material
US7888062B1 (en) 2010-02-01 2011-02-15 Microbios, Inc. Process and composition for the manufacture of a microbial-based product
US8951512B2 (en) 2010-05-04 2015-02-10 New York University Methods for treating bone disorders by characterizing and restoring mammalian bacterial microbiota
KR20110124976A (ko) * 2010-05-12 2011-11-18 일동제약주식회사 장내 유해세균 억제능과 면역 증강작용을 하는 클로스트리디움 부티리쿰 아이디씨씨 9207 백미 발효물
US9206680B2 (en) 2010-06-16 2015-12-08 Taxon Biosciences Inc Compositions and methods for identifying and modifying carbonaceous compositions
WO2012077038A1 (en) 2010-12-06 2012-06-14 Degama Berrier Ltd. Composition and method for improving stability and extending shelf life of probiotic bacteria and food products thereof
RU2458527C1 (ru) 2010-12-30 2012-08-20 Общество с ограниченной ответственностью "БИОТРОФ" Способ получения препарата для кормления сельскохозяйственных животных и птицы и способ приготовления корма на его основе
GB201102865D0 (en) 2011-02-18 2011-04-06 Danisco Feed additive composition
WO2012122522A2 (en) 2011-03-09 2012-09-13 Washington University Cultured collection of gut microbial community
US20140171339A1 (en) 2011-06-06 2014-06-19 The University Of North Carolina At Chapel Hill Methods and kits for detecting adenomas, colorectal cancer, and uses thereof
EP3569690B1 (en) 2011-12-01 2024-08-28 The University of Tokyo Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
CN104363769B (zh) 2012-02-28 2016-08-24 康奈尔大学 益生菌组合物和方法
CN102533621B (zh) 2012-03-01 2015-04-22 中国农业大学 一种酵母培养物在促进纤维素分解菌增殖中的应用
US9562271B2 (en) 2012-04-20 2017-02-07 T2 Biosystems, Inc. Compositions and methods for detection of Candida species
KR101451272B1 (ko) 2012-05-15 2014-10-16 (주)바이오토피아 희토 원소가 축적된 피치아 커드리아브제비 la30 균체 및 이의 제조방법
US9551021B2 (en) 2012-05-18 2017-01-24 Washington University Methods and compositions for detecting pathogenic bacteria
CN102899272B (zh) 2012-10-16 2014-07-09 中国农业大学 一种诱导细菌进入活的非可培养状态的方法
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
CN103053860B (zh) * 2013-01-31 2014-03-26 济南百事得牧业科技有限公司 一种含有毕赤酵母的奶牛饲料及其生产方法
KR102222273B1 (ko) 2013-02-04 2021-03-08 세레스 테라퓨틱스, 인코포레이티드 조성물 및 방법
US9909180B2 (en) 2013-02-04 2018-03-06 The Board Of Trustees Of The Leland Stanford Junior University Measurement and comparison of immune diversity by high-throughput sequencing
WO2014141274A1 (en) 2013-03-14 2014-09-18 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Microbial compositions comprising rumen microflora and uses thereof
US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
MX372592B (es) 2013-06-26 2020-04-20 Indigo Ag Inc Poblaciones endofitas derivadas de semillas, composiciones y metodos de uso
WO2015023461A2 (en) 2013-08-06 2015-02-19 The Trustees Of The University Of Pennsylvania Influenza nucleic acid molecules and vaccines made therefrom
IN2013MU03532A (enExample) 2013-11-08 2015-09-25 Hindustan Petroleum Corp Ltd
CN104694533A (zh) 2013-12-09 2015-06-10 江苏命码生物科技有限公司 沙门氏菌的非编码性rna及其鉴定和应用
US10287637B2 (en) 2014-01-25 2019-05-14 uBiome, Inc. Method and system for microbiome analysis
CN113249435B (zh) 2014-06-26 2024-09-03 10X基因组学有限公司 分析来自单个细胞或细胞群体的核酸的方法
US11227667B2 (en) 2014-07-11 2022-01-18 Matatu, Inc. Use of a gut microbiome as a predictor of animal growth or health
WO2016011511A1 (en) 2014-07-25 2016-01-28 The University Of Queensland Bacillus amyloliquefaciens probiotic compositions, methods of production, and methods of use
HRP20230358T1 (hr) 2014-08-06 2023-06-09 Envera Lic, Llc Pripravci bakterijskih spora za industrijske uporabe
US10357157B2 (en) 2014-10-21 2019-07-23 uBiome, Inc. Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
CN104611273B (zh) 2015-02-11 2017-10-31 成都与康科技有限公司 丁酸梭菌ucn‑12菌株及其组合物和应用
HK1246373A1 (zh) 2015-02-27 2018-09-07 Alere Inc. 微生物群诊断
KR101773059B1 (ko) 2015-03-26 2017-08-31 한국생명공학연구원 면역 증진 및 항바이러스 활성을 가지는 클로스트리디움 부티리쿰 균주 및 이의 용도
CN104814278A (zh) 2015-04-15 2015-08-05 江苏师范大学 一种提高奶牛产奶量的微生态制剂
US10865434B2 (en) 2015-04-21 2020-12-15 General Automation Lab Technologies Inc. High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications
EP3285926B1 (en) 2015-04-21 2022-03-02 General Automation Lab Technologies Inc. Kit and method for high throughput microbiology applications
US10851399B2 (en) 2015-06-25 2020-12-01 Native Microbials, Inc. Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
US9938558B2 (en) 2015-06-25 2018-04-10 Ascus Biosciences, Inc. Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon
MX388995B (es) 2015-06-25 2025-03-20 Native Microbials Inc Métodos, aparatos y sistemas para analizar cepas de microorganismos de comunidades heterogéneas complejas, predecir e indentificar sus relaciones funcionales e interacciones y seleccionar y sintetizar conjuntos microbianos basados en estos.
NZ743958A (en) 2016-01-07 2023-07-28 Native Microbials Inc Methods for improving milk production by administration of microbial consortia
CN108777967B (zh) 2016-01-29 2021-12-17 艾姆瓦克化学公司 微生物聚生体
WO2017139690A1 (en) 2016-02-11 2017-08-17 10X Genomics, Inc. Cell population analysis using single nucleotide polymorphisms from single cell transcriptomes
CN109874294B (zh) 2016-04-15 2023-06-20 原生微生物股份有限公司 通过施用微生物聚生体或其纯化菌株来提高禽类的农业生产的方法
BR122022006025B1 (pt) 2016-04-26 2023-05-16 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Método para determinar eficiência alimentar ou produção de metano de animal ruminante
US10428370B2 (en) 2016-09-15 2019-10-01 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
JP2020507308A (ja) 2016-12-28 2020-03-12 アスカス バイオサイエンシーズ, インコーポレイテッド 複雑な不均一コミュニティの微生物株の解析、その機能的関連性及び相互作用の決定、ならびにそれに基づく診断及び生物学的状態の管理、のための方法、装置、及びシステム
CN110352250A (zh) 2016-12-28 2019-10-18 埃斯库斯生物科技股份公司 用于通过示踪剂分析法对复杂异质群落进行微生物株系分析、确定其功能关系及相互作用以及合成包括给药微生物群集和接种微生物群集的微生物群集的方法、设备和系统
AU2017386658A1 (en) 2016-12-28 2019-07-25 Native Microbials, Inc. Methods, apparatuses, and systems for analyzing complete microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and identifying and synthesizing bioreactive modificators based thereon
WO2018201049A1 (en) 2017-04-28 2018-11-01 Ascus Biosciences, Inc. Methods for supporting grain intensive and/or energy intensive diets in ruminants with a synthetic bioensemble of microbes
CN107173587B (zh) 2017-07-06 2020-08-28 浙江亚林生物科技股份有限公司 一种含有富硒铁皮石斛益生菌的复合饲料及其制备方法
KR101934400B1 (ko) 2017-07-12 2019-03-25 씨제이제일제당 주식회사 바실러스 서브틸리스 및 바실러스 리체니포미스를 포함하는 사료 첨가제, 상기 첨가제를 포함하는 사료 조성물 및 상기 사료첨가제의 제조 방법
WO2019075028A1 (en) 2017-10-12 2019-04-18 Syngenta Participations Ag ENHANCED ANIMAL FEEDING COMPOSITIONS AND METHODS OF USE
EP3931300A4 (en) 2019-02-28 2022-11-23 Native Microbials, Inc. METHODS, DEVICES AND SYSTEMS FOR IMPROVING YIELD IN MICROBIAL PRESERVATION BY RESCUE AND SERIAL PASSAGE OF PRESERVED CELLS
WO2021202804A1 (en) 2020-03-31 2021-10-07 Native Microbials, Inc. Improving milk production and compositional characteristics with novel ruminococcus bovis
EP4228412A4 (en) 2020-10-16 2024-11-20 Native Microbials, Inc. METHODS FOR MANAGING INTENSIVE GRAIN-RICH DIETS IN RUMINANTS INCLUDING ADMINISTRATION OF CHORDICOCCUS SP
AR125444A1 (es) 2021-04-22 2023-07-19 Native Microbials Inc Composiciones y métodos para mejorar el rendimiento lácteo y las características composicionales de los lácteos en rumiantes

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