CA2959220A1 - Mutant csgg pores - Google Patents
Mutant csgg pores Download PDFInfo
- Publication number
- CA2959220A1 CA2959220A1 CA2959220A CA2959220A CA2959220A1 CA 2959220 A1 CA2959220 A1 CA 2959220A1 CA 2959220 A CA2959220 A CA 2959220A CA 2959220 A CA2959220 A CA 2959220A CA 2959220 A1 CA2959220 A1 CA 2959220A1
- Authority
- CA
- Canada
- Prior art keywords
- pore
- csgg
- iii
- viii
- vii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/22—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a Strep-tag
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/116—Nucleic acid detection characterized by the use of physical, structural and functional properties electrical properties of nucleic acids, e.g. impedance, conductivity or resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/60—Detection means characterised by use of a special device
- C12Q2565/631—Detection means characterised by use of a special device being a biochannel or pore
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1415455.3 | 2014-09-01 | ||
| GB201415455A GB201415455D0 (en) | 2014-09-01 | 2014-09-01 | Protein pores and sensing applications |
| GB1422079.2 | 2014-12-11 | ||
| GB201422079 | 2014-12-11 | ||
| GBGB1506489.2A GB201506489D0 (en) | 2014-09-01 | 2015-04-16 | Protein pores for sensing applications |
| GB1506489.2 | 2015-04-16 | ||
| GB1506754.9 | 2015-04-21 | ||
| GBGB1506754.9A GB201506754D0 (en) | 2015-04-21 | 2015-04-21 | Mutant pore |
| GB1508287.8 | 2015-05-14 | ||
| GBGB1508287.8A GB201508287D0 (en) | 2015-05-14 | 2015-05-14 | Mutant pores |
| GB1511203.0 | 2015-06-25 | ||
| GBGB1511203.0A GB201511203D0 (en) | 2015-06-25 | 2015-06-25 | Mutant pore |
| GB1515240.8 | 2015-08-27 | ||
| GBGB1515240.8A GB201515240D0 (en) | 2015-08-27 | 2015-08-27 | Mutant pore |
| PCT/EP2015/069965 WO2016034591A2 (en) | 2014-09-01 | 2015-09-01 | Mutant pores |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2959220A1 true CA2959220A1 (en) | 2016-03-10 |
Family
ID=55440449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2959220A Pending CA2959220A1 (en) | 2014-09-01 | 2015-09-01 | Mutant csgg pores |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US10400014B2 (enExample) |
| EP (2) | EP3224274B1 (enExample) |
| JP (4) | JP7161291B2 (enExample) |
| KR (3) | KR102851011B1 (enExample) |
| CN (7) | CN117164683A (enExample) |
| AU (1) | AU2015310913B2 (enExample) |
| CA (1) | CA2959220A1 (enExample) |
| WO (1) | WO2016034591A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117106038A (zh) * | 2017-06-30 | 2023-11-24 | 弗拉芒区生物技术研究所 | 新颖蛋白孔 |
Families Citing this family (131)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0905140D0 (en) | 2009-03-25 | 2009-05-06 | Isis Innovation | Method |
| EP3848706B1 (en) | 2011-05-27 | 2023-07-19 | Oxford Nanopore Technologies PLC | Coupling method |
| BR112014001699A2 (pt) | 2011-07-25 | 2017-06-13 | Oxford Nanopore Tech Ltd | método para sequenciar de um polinucleotídeo alvo de filamento duplo, kit, métodos para preparar um polinucleotídeo alvo de filamento duplo para sequenciamento e para sequenciar um polinucleotídeo alvo de filamento duplo, e, aparelho |
| KR20140090633A (ko) | 2011-10-21 | 2014-07-17 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 포어 및 hel308 헬리카제를 사용하여 표적 폴리뉴클레오티드를 특성화하는 방법 |
| GB201202519D0 (en) | 2012-02-13 | 2012-03-28 | Oxford Nanopore Tech Ltd | Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules |
| CA2869546C (en) | 2012-04-10 | 2020-07-21 | Oxford Nanopore Technologies Limited | Mutant lysenin pores |
| JP6614972B2 (ja) | 2012-07-19 | 2019-12-04 | オックスフォード ナノポール テクノロジーズ リミテッド | 修飾ヘリカーゼ |
| EP2875154B1 (en) | 2012-07-19 | 2017-08-23 | Oxford Nanopore Technologies Limited | SSB method for characterising a nucleic acid |
| GB201222928D0 (en) | 2012-12-19 | 2013-01-30 | Oxford Nanopore Tech Ltd | Analysis of a polynucleotide |
| AU2014224432B2 (en) | 2013-03-08 | 2019-10-24 | Oxford Nanopore Technologies Limited | Enzyme stalling method |
| GB201313477D0 (en) | 2013-07-29 | 2013-09-11 | Univ Leuven Kath | Nanopore biosensors for detection of proteins and nucleic acids |
| CN118086476A (zh) | 2013-10-18 | 2024-05-28 | 牛津纳米孔科技公开有限公司 | 经修饰的酶 |
| GB201406155D0 (en) | 2014-04-04 | 2014-05-21 | Oxford Nanopore Tech Ltd | Method |
| WO2015110813A1 (en) | 2014-01-22 | 2015-07-30 | Oxford Nanopore Technologies Limited | Method for attaching one or more polynucleotide binding proteins to a target polynucleotide |
| EP3137490B1 (en) | 2014-05-02 | 2021-01-27 | Oxford Nanopore Technologies Limited | Mutant pores |
| GB201417712D0 (en) | 2014-10-07 | 2014-11-19 | Oxford Nanopore Tech Ltd | Method |
| WO2016034591A2 (en) | 2014-09-01 | 2016-03-10 | Vib Vzw | Mutant pores |
| EP3204511B1 (en) | 2014-10-07 | 2021-07-28 | Oxford Nanopore Technologies Limited | Mutant pores |
| EP4397972A3 (en) | 2014-10-16 | 2024-10-09 | Oxford Nanopore Technologies PLC | Alignment mapping estimation |
| GB201502809D0 (en) | 2015-02-19 | 2015-04-08 | Oxford Nanopore Tech Ltd | Mutant pore |
| GB201502810D0 (en) | 2015-02-19 | 2015-04-08 | Oxford Nanopore Tech Ltd | Method |
| WO2016166232A1 (en) | 2015-04-14 | 2016-10-20 | Katholieke Universiteit Leuven | Nanopores with internal protein adaptors |
| GB201508669D0 (en) | 2015-05-20 | 2015-07-01 | Oxford Nanopore Tech Ltd | Methods and apparatus for forming apertures in a solid state membrane using dielectric breakdown |
| WO2017004504A1 (en) | 2015-07-02 | 2017-01-05 | The University Of Massachusetts | Membrane and droplet-interface bilayer systems and methods |
| JP7237586B2 (ja) | 2015-12-08 | 2023-03-13 | カトリック ユニヴェルシテット ルーヴェン カーユー ルーヴェン リサーチ アンド ディベロップメント | 修飾ナノポア、それを含む組成物およびその使用 |
| AU2017225374B2 (en) | 2016-03-02 | 2020-03-05 | Oxford Nanopore Technologies Limited | Mutant pore |
| CA3020203A1 (en) | 2016-04-06 | 2017-10-12 | Oxford Nanopore Technologies Limited | Mutant pore |
| GB201609221D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
| GB201609220D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
| CN109196116B (zh) | 2016-05-25 | 2022-09-27 | 牛津纳米孔科技公开有限公司 | 一种表征靶多核苷酸的方法 |
| GB201611770D0 (en) | 2016-07-06 | 2016-08-17 | Oxford Nanopore Tech | Microfluidic device |
| GB201616590D0 (en) | 2016-09-29 | 2016-11-16 | Oxford Nanopore Technologies Limited | Method |
| GB201617886D0 (en) | 2016-10-21 | 2016-12-07 | Oxford Nanopore Technologies Limited | Method |
| GB201619930D0 (en) | 2016-11-24 | 2017-01-11 | Oxford Nanopore Tech | Apparatus and methods for controlling insertion of a membrane channel into a membrane |
| GB201620450D0 (en) | 2016-12-01 | 2017-01-18 | Oxford Nanopore Tech Ltd | Method |
| EP3580228B1 (en) | 2017-02-10 | 2021-07-28 | Oxford Nanopore Technologies Limited | Modified nanopores, compositions comprising the same, and uses thereof |
| WO2018170362A2 (en) * | 2017-03-16 | 2018-09-20 | The Penn State Research Foundation | Versatile display scaffolds for proteins |
| GB201707140D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Method |
| GB201707122D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Pore |
| GB201707138D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Machine learning analysis of nanopore measurements |
| EP3957990A1 (en) | 2017-06-29 | 2022-02-23 | President and Fellows of Harvard College | Deterministic stepping of polymers through a nanopore |
| EP4303317A3 (en) * | 2017-10-23 | 2024-04-24 | F. Hoffmann-La Roche AG | Removing and reinserting protein nanopores in a membrane using osmotic imbalance |
| GB2568895B (en) | 2017-11-29 | 2021-10-27 | Oxford Nanopore Tech Ltd | Microfluidic device |
| GB2569630B (en) | 2017-12-21 | 2022-10-12 | Sharp Life Science Eu Ltd | Droplet Interfaces in Electro-wetting Devices |
| GB201801768D0 (en) | 2018-02-02 | 2018-03-21 | Oxford Nanopore Tech Ltd | Synthesis method |
| GB2574048B (en) | 2018-05-24 | 2021-06-16 | Oxford Nanopore Tech Ltd | Nanopore sensor component with electrostatic discharge protection |
| US12269037B2 (en) | 2018-05-24 | 2025-04-08 | Oxford Nanopore Technologies Plc | Droplet interfaces in electro-wetting devices |
| GB201808556D0 (en) | 2018-05-24 | 2018-07-11 | Oxford Nanopore Tech Ltd | Method |
| GB201809323D0 (en) | 2018-06-06 | 2018-07-25 | Oxford Nanopore Tech Ltd | Method |
| KR20210025046A (ko) * | 2018-06-08 | 2021-03-08 | 가부시키가이샤 모달리스 | 개변된 Cas9 단백질 및 그의 용도 |
| GB201812615D0 (en) | 2018-08-02 | 2018-09-19 | Ucl Business Plc | Membrane bound nucleic acid nanopores |
| GB201814369D0 (en) | 2018-09-04 | 2018-10-17 | Oxford Nanopore Tech Ltd | Method for determining a polymersequence |
| CN112823392B (zh) * | 2018-10-12 | 2024-09-03 | 生命科技股份有限公司 | 用于评估微卫星不稳定性状态的方法和系统 |
| GB201818216D0 (en) | 2018-11-08 | 2018-12-26 | Oxford Nanopore Tech Ltd | Pore |
| CN113195736A (zh) * | 2018-11-08 | 2021-07-30 | 牛津纳米孔科技公司 | 孔 |
| JP7520833B2 (ja) | 2018-11-28 | 2024-07-23 | オックスフォード ナノポール テクノロジーズ ピーエルシー | 感知システムおよび動作方法 |
| GB201819378D0 (en) | 2018-11-28 | 2019-01-09 | Oxford Nanopore Tech Ltd | Analysis of nanopore signal using a machine-learning technique |
| GB201821155D0 (en) | 2018-12-21 | 2019-02-06 | Oxford Nanopore Tech Ltd | Method |
| CN111499705B (zh) * | 2019-01-30 | 2023-08-08 | 深圳市梅丽纳米孔科技有限公司 | 一种突变NfpAB纳米孔、测试系统及制作方法与应用 |
| US11789006B2 (en) | 2019-03-12 | 2023-10-17 | Oxford Nanopore Technologies Plc | Nanopore sensing device, components and method of operation |
| GB2580988B (en) | 2019-03-19 | 2022-04-13 | Oxford Nanopore Tech Ltd | Current measurement apparatus, molecular entity sensing apparatus, method of measuring a current, method of sensing a molecular entity |
| AU2020272997A1 (en) * | 2019-04-09 | 2021-10-21 | Oxford Nanopore Technologies Plc | Pore |
| GB201907244D0 (en) | 2019-05-22 | 2019-07-03 | Oxford Nanopore Tech Ltd | Method |
| GB201907246D0 (en) | 2019-05-22 | 2019-07-03 | Oxford Nanopore Tech Ltd | Method |
| GB201907243D0 (en) | 2019-05-22 | 2019-07-03 | Oxford Nanopore Tech Ltd | Sensing interactions between molecular entities and nanapores |
| US11926819B2 (en) | 2019-05-28 | 2024-03-12 | The Regents Of The University Of California | Methods of adding polymers to ribonucleic acids |
| GB201915480D0 (en) | 2019-10-25 | 2019-12-11 | Oxford Nanopore Tech Ltd | Improved nanopore sensing device, components and method of manufacture |
| GB201917060D0 (en) | 2019-11-22 | 2020-01-08 | Oxford Nanopore Tech Ltd | Method |
| AU2020395930A1 (en) | 2019-12-02 | 2022-05-26 | Oxford Nanopore Technologies Plc | Method of characterising a target polypeptide using a nanopore |
| GB201917742D0 (en) | 2019-12-04 | 2020-01-15 | Oxford Nanopore Tech Ltd | Method |
| CN115605612A (zh) * | 2020-03-25 | 2023-01-13 | 通用测序技术公司（Us） | 直接连接到纳米间隙装置的酶突变体 |
| GB202004944D0 (en) | 2020-04-03 | 2020-05-20 | King S College London | Method |
| GB202016874D0 (en) | 2020-10-23 | 2020-12-09 | Oxford Nanopore Tech Ltd | Nanopore support structure and manufacture thereof |
| US20230295712A1 (en) | 2020-06-18 | 2023-09-21 | Oxford Nanopore Technologies Plc | A method of selectively characterising a polynucleotide using a detector |
| GB202009349D0 (en) | 2020-06-18 | 2020-08-05 | Oxford Nanopore Tech Ltd | Method |
| CN115968410A (zh) | 2020-06-18 | 2023-04-14 | 牛津纳米孔科技公开有限公司 | 表征移动穿过纳米孔的多核苷酸的方法 |
| WO2022013551A1 (en) | 2020-07-17 | 2022-01-20 | Oxford Nanopore Technologies Limited | Nanopore sensing device |
| CN116368095A (zh) | 2020-07-22 | 2023-06-30 | 牛津纳米孔科技公开有限公司 | 固态纳米孔形成 |
| WO2022243692A1 (en) | 2021-05-19 | 2022-11-24 | Oxford Nanopore Technologies Plc | Methods for complement strand sequencing |
| GB202107192D0 (en) | 2021-05-19 | 2021-06-30 | Oxford Nanopore Tech Ltd | Method |
| GB202107354D0 (en) | 2021-05-24 | 2021-07-07 | Oxford Nanopore Tech Ltd | Method |
| US20240352516A1 (en) * | 2021-08-18 | 2024-10-24 | Qitan Technology Ltd., Chengdu | Mutant of pore protein monomer, protein pore, and use thereof |
| CN113651876B (zh) * | 2021-08-18 | 2024-02-02 | 成都齐碳科技有限公司 | 孔蛋白单体的突变体、蛋白孔及其应用 |
| CN113480620B (zh) * | 2021-08-18 | 2024-02-06 | 成都齐碳科技有限公司 | 孔蛋白单体的突变体、蛋白孔及其应用 |
| US20250136647A1 (en) * | 2021-08-18 | 2025-05-01 | Qitan Technology Ltd., Chengdu | Mutant of porin monomer, protein pore and application thereof |
| GB2610380A (en) | 2021-08-23 | 2023-03-08 | Cambridge Entpr Ltd | Nucleic acid detection |
| GB202112235D0 (en) | 2021-08-26 | 2021-10-13 | Oxford Nanopore Tech Ltd | Nanopore |
| CN113735948B (zh) * | 2021-09-28 | 2024-02-02 | 成都齐碳科技有限公司 | 孔蛋白单体的突变体、蛋白孔及其应用 |
| GB202113935D0 (en) | 2021-09-29 | 2021-11-10 | Cambridge Entpr Ltd | Nucleic acid characterisation |
| CN113896776B (zh) * | 2021-10-12 | 2024-02-06 | 成都齐碳科技有限公司 | 孔蛋白单体的突变体、蛋白孔及其应用 |
| CN113754743B (zh) * | 2021-10-12 | 2024-02-02 | 成都齐碳科技有限公司 | 孔蛋白单体的突变体、蛋白孔及其应用 |
| CN113912683B (zh) * | 2021-10-12 | 2024-02-06 | 成都齐碳科技有限公司 | 孔蛋白单体的突变体、蛋白孔及其应用 |
| CN113773373B (zh) * | 2021-10-12 | 2024-02-06 | 成都齐碳科技有限公司 | 孔蛋白单体的突变体、蛋白孔及其应用 |
| JP2024542960A (ja) | 2021-11-29 | 2024-11-19 | オックスフォード ナノポール テクノロジーズ ピーエルシー | ナノ細孔測定信号分析 |
| GB202118906D0 (en) | 2021-12-23 | 2022-02-09 | Oxford Nanopore Tech Ltd | Method |
| GB202118908D0 (en) | 2021-12-23 | 2022-02-09 | Oxford Nanopore Tech Ltd | Method |
| GB202205617D0 (en) | 2022-04-14 | 2022-06-01 | Oxford Nanopore Tech Plc | Novel modified protein pores and enzymes |
| CN114957412B (zh) * | 2022-04-28 | 2024-09-17 | 清华大学 | 一种新型孔蛋白单体及其应用 |
| AU2023270700A1 (en) | 2022-05-17 | 2024-10-31 | Oxford Nanopore Technologies Plc | Method and adaptors |
| GB202207267D0 (en) | 2022-05-18 | 2022-06-29 | Oxford Nanopore Tech Plc | Calibration and profiling of a nanopore array device |
| GB202211607D0 (en) | 2022-08-09 | 2022-09-21 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
| EP4569331A1 (en) | 2022-08-09 | 2025-06-18 | Oxford Nanopore Technologies PLC | De novo pores |
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| CA3020203A1 (en) | 2016-04-06 | 2017-10-12 | Oxford Nanopore Technologies Limited | Mutant pore |
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| CN110914290A (zh) | 2017-06-30 | 2020-03-24 | 弗拉芒区生物技术研究所 | 新颖蛋白孔 |
| CN113195736A (zh) | 2018-11-08 | 2021-07-30 | 牛津纳米孔科技公司 | 孔 |
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2015
- 2015-09-01 WO PCT/EP2015/069965 patent/WO2016034591A2/en not_active Ceased
- 2015-09-01 JP JP2017512039A patent/JP7161291B2/ja active Active
- 2015-09-01 CN CN202311131390.1A patent/CN117164683A/zh active Pending
- 2015-09-01 US US15/507,947 patent/US10400014B2/en active Active
- 2015-09-01 CA CA2959220A patent/CA2959220A1/en active Pending
- 2015-09-01 CN CN201580059505.8A patent/CN107207570A/zh active Pending
- 2015-09-01 CN CN202311131934.4A patent/CN117164684A/zh active Pending
- 2015-09-01 CN CN202210259153.2A patent/CN114605507B/zh active Active
- 2015-09-01 CN CN202510056986.2A patent/CN119899249A/zh active Pending
- 2015-09-01 KR KR1020237027865A patent/KR102851011B1/ko active Active
- 2015-09-01 EP EP15759438.3A patent/EP3224274B1/en active Active
- 2015-09-01 EP EP22150770.0A patent/EP4053150A1/en active Pending
- 2015-09-01 KR KR1020177008588A patent/KR20170042794A/ko not_active Ceased
- 2015-09-01 CN CN202311128619.6A patent/CN117164682A/zh active Pending
- 2015-09-01 KR KR1020257028018A patent/KR20250130441A/ko active Pending
- 2015-09-01 AU AU2015310913A patent/AU2015310913B2/en active Active
- 2015-09-01 CN CN202311730120.2A patent/CN117700500B/zh active Active
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2019
- 2019-07-25 US US16/522,591 patent/US11034734B2/en active Active
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- 2020-12-09 JP JP2020204136A patent/JP2021078500A/ja active Pending
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- 2021-03-08 US US17/194,821 patent/US12275761B2/en active Active
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- 2022-08-25 JP JP2022133867A patent/JP2022177005A/ja active Pending
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- 2024-05-27 JP JP2024085524A patent/JP2024122996A/ja active Pending
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- 2025-03-03 US US19/069,041 patent/US20260015392A1/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117106038A (zh) * | 2017-06-30 | 2023-11-24 | 弗拉芒区生物技术研究所 | 新颖蛋白孔 |
| CN117106038B (zh) * | 2017-06-30 | 2025-12-09 | 弗拉芒区生物技术研究所 | 新颖蛋白孔 |
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