CA2884000C - Method for culturing mesenchymal stem cells - Google Patents
Method for culturing mesenchymal stem cells Download PDFInfo
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- CA2884000C CA2884000C CA2884000A CA2884000A CA2884000C CA 2884000 C CA2884000 C CA 2884000C CA 2884000 A CA2884000 A CA 2884000A CA 2884000 A CA2884000 A CA 2884000A CA 2884000 C CA2884000 C CA 2884000C
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- stem cells
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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| WO2015170347A2 (en) * | 2014-05-09 | 2015-11-12 | Reelabs Private Limited | Foetal polymix of mesenchymal stem cells under hypoxic conditions for the treatment of clinical disorders |
| JP6519727B2 (ja) * | 2014-09-17 | 2019-05-29 | 国立大学法人山口大学 | 間葉系幹細胞の培養方法、および肝機能障害用治療剤の製造方法 |
| US11000694B2 (en) | 2014-10-24 | 2021-05-11 | The Board Of Trustees Of The University Of Illinois | Use of lasers for treating and reversing fibrosis |
| JP6494756B2 (ja) * | 2014-10-29 | 2019-04-03 | アール バイオ カンパニー リミテッドＲ Ｂｉｏ Ｃｏ．， Ｌｔｄ． | 幹細胞培養のための培地組成物 |
| TWI740812B (zh) * | 2015-01-05 | 2021-10-01 | 國立陽明大學 | 用於治療肝臟疾病的間葉幹細胞 |
| JP2018512061A (ja) * | 2015-02-20 | 2018-05-10 | ナショナル ヤン−ミン ユニバーシティ | 骨関節炎処置のための間葉幹細胞の使用 |
| WO2016184427A1 (zh) * | 2015-05-21 | 2016-11-24 | 中国科学院上海生命科学研究院 | 低氧处理的间充质干细胞及其应用 |
| WO2017155325A1 (ko) * | 2016-03-09 | 2017-09-14 | 울산대학교 산학협력단 | Jak1 억제제를 유효성분으로 포함하는 줄기세포의 증식, 분화 촉진 또는 노화 억제용 조성물 |
| KR102737245B1 (ko) * | 2016-03-31 | 2024-12-02 | 샌바이오, 인크. | 줄기 세포 배양 및 치료를 위한 배지, 방법, 세포 및 분비 인자 |
| WO2018226640A1 (en) * | 2017-06-05 | 2018-12-13 | The Regents Of The University Of The University Of California | Compositions for treating retinal diseases and methods for making and using them |
| CA3068685A1 (en) | 2017-06-27 | 2019-01-03 | Ajinomoto Co., Inc. | Riboflavin derivative-containing medium |
| CN107384858A (zh) * | 2017-08-17 | 2017-11-24 | 成都康景生物科技有限公司 | 一种缺氧耐受型间充质干细胞的制备方法及其应用 |
| CN109666631A (zh) * | 2017-10-17 | 2019-04-23 | 澳门大学 | 增强干细胞活性的培养方法、应用以及用于治疗中枢神经疾病的制剂、制备方法及治疗方法 |
| CN109706115B (zh) * | 2017-10-26 | 2023-05-30 | 中国医科大学 | 一种小鼠骨髓间充质干细胞细胞系的构建方法 |
| CN108359637B (zh) * | 2018-02-14 | 2021-09-28 | 浙江生创精准医疗科技有限公司 | 一种宫血干细胞快速扩增的方法 |
| CN109517786B (zh) * | 2018-10-18 | 2022-06-17 | 广州元帅生物科技有限公司 | 一种具有修复功能的多能干细胞制剂及其应用 |
| US20220348880A1 (en) * | 2019-08-30 | 2022-11-03 | The Texas A&M University System | Xenogen-Free Mesenchymal Stem Cell Compositions and Methods of Use |
| WO2022004938A1 (ko) * | 2020-06-30 | 2022-01-06 | 주식회사 미래셀바이오 | 유사 중간엽 줄기세포의 제조방법 |
| CN112147340B (zh) * | 2020-09-30 | 2024-03-08 | 北京银丰鼎诚生物工程技术有限公司 | 一种神经干细胞免疫调节功能的检测方法 |
| CN112375733B (zh) * | 2020-11-03 | 2022-09-02 | 中国人民解放军陆军军医大学第一附属医院 | 可增进间充质干细胞干细胞性的植物血凝素及其在间充质干细胞扩增培养中的应用 |
| KR102435452B1 (ko) * | 2020-11-11 | 2022-09-07 | 이엔셀 주식회사 | 노화가 감소되고 줄기세포능이 보존된 초기 중간엽 줄기세포, 및 그 배양방법 |
| CN113502261B (zh) * | 2021-07-16 | 2023-08-29 | 上海东方星际干细胞科技有限公司 | 一种能高效分化成脂的规模化3d低氧间充质干细胞培养体系 |
| CN116218770B (zh) * | 2022-12-30 | 2023-11-24 | 苏州科为康生物医药科技有限公司 | 一种间充质干细胞的制备方法和应用 |
| CN117660325B (zh) * | 2024-01-31 | 2024-04-19 | 苏州科为康生物医药科技有限公司 | 一种制备脐带血msc的培养基及其方法 |
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| ES2672815T3 (es) * | 2001-10-18 | 2018-06-18 | Lifecell Corporation | Remodelación de tejidos y órganos |
| CN1281739C (zh) | 2002-02-19 | 2006-10-25 | 美迪宝斯特有限公司 | 从脐带血中分离并扩大培养间充质干细胞/祖细胞及将脐带血来源的间充质干细胞/祖细胞分化成各种间充质组织的方法 |
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| WO2005028678A2 (en) * | 2003-06-06 | 2005-03-31 | Wyeth | Methods and materials for identifying agents which modulate bone remodeling and agents identified thereby |
| JP2006055106A (ja) | 2004-08-23 | 2006-03-02 | National Institute Of Advanced Industrial & Technology | ヒト血清培地を用いるヒト骨髄由来間葉系幹細胞培養法 |
| EP2471904B1 (en) * | 2005-12-29 | 2018-10-24 | Celularity, Inc. | Placental stem cell populations |
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| EP2687220A3 (en) * | 2007-02-12 | 2014-05-14 | Anthrogenesis Corporation | Treatment of inflammatory diseases using placental stem cells |
| US8114668B2 (en) * | 2007-05-14 | 2012-02-14 | Cardiac Pacemakers, Inc. | Composition for cold storage of stem cells |
| JP5349474B2 (ja) * | 2007-07-20 | 2013-11-20 | ドングク・ユニヴァーシティー・インダストリー−アカデミック・コーオペレーション・ファンデーション | 間葉系幹細胞を利用して毛乳頭組職を製造する方法 |
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| ES2352046T3 (es) * | 2007-09-21 | 2011-02-15 | Universität Leipzig | Medio de cultivo celular y procedimiento de cultivo de células madre y células progenitor. |
| US20100330047A1 (en) * | 2009-06-26 | 2010-12-30 | Life & Light Ltd. | Mesenchymal Stem Cells Grown Under Hypoxic Conditions: Compositions, Methods and Uses Therefor |
| KR101243276B1 (ko) * | 2009-10-08 | 2013-03-13 | 서울대학교병원 | 인간 지방 줄기세포의 고활성을 유도하는 방법 및 배지 |
| PT2602310T (pt) * | 2010-08-03 | 2020-03-11 | Univ Sapporo Medical | Sistema de cultura de células de medula óssea que contém autossoro, método de cultura de células de medula óssea que contém autossoro, e método para produzir composição medicinal compreendendo células de medula óssea cultivadas com autossoro como ingrediente ativo |
| US20120052577A1 (en) | 2010-08-31 | 2012-03-01 | The Regents Of The University Of California | Culture system for stem cell propagation and neural and oligodendrocyte specification |
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| EP2893001A4 (en) | 2016-03-09 |
| KR101532556B1 (ko) | 2015-06-30 |
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| AU2013309642A1 (en) | 2015-03-26 |
| CN104781394B (zh) | 2017-12-12 |
| CN104781394A (zh) | 2015-07-15 |
| CA2884000A1 (en) | 2014-03-06 |
| JP2015532596A (ja) | 2015-11-12 |
| EP2893001A1 (en) | 2015-07-15 |
| WO2014035215A1 (en) | 2014-03-06 |
| PT2893001T (pt) | 2019-12-09 |
| DK2893001T3 (da) | 2019-12-02 |
| KR20140030703A (ko) | 2014-03-12 |
| US20150284686A1 (en) | 2015-10-08 |
| ES2755802T3 (es) | 2020-04-23 |
| US9580687B2 (en) | 2017-02-28 |
| PL2893001T3 (pl) | 2020-03-31 |
| US20190218517A1 (en) | 2019-07-18 |
| EP2893001B1 (en) | 2019-10-30 |
| AU2013309642B2 (en) | 2018-10-25 |
| IN2015DN01737A (enExample) | 2015-05-29 |
| JP6478243B2 (ja) | 2019-03-06 |
| US11332715B2 (en) | 2022-05-17 |
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