CA2869954C - Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof in medical conditions related to modulation of bruton's tyrosine kinase activity - Google Patents
Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof in medical conditions related to modulation of bruton's tyrosine kinase activity Download PDFInfo
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- CA2869954C CA2869954C CA2869954A CA2869954A CA2869954C CA 2869954 C CA2869954 C CA 2869954C CA 2869954 A CA2869954 A CA 2869954A CA 2869954 A CA2869954 A CA 2869954A CA 2869954 C CA2869954 C CA 2869954C
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- Prior art keywords
- dihydro
- pyrrolo
- benzoxazepin
- hydroxymethyl
- crarb
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- 108010029445 Agammaglobulinaemia Tyrosine Kinase Proteins 0.000 title abstract description 9
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- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1573/CHE/2012 | 2012-04-20 | ||
| IN1573CH2012 IN2012CH01573A (instruction) | 2012-04-20 | 2013-04-18 | |
| PCT/IN2013/000259 WO2013157022A1 (en) | 2012-04-20 | 2013-04-18 | Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2869954A1 CA2869954A1 (en) | 2013-10-24 |
| CA2869954C true CA2869954C (en) | 2023-01-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2869954A Active CA2869954C (en) | 2012-04-20 | 2013-04-18 | Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof in medical conditions related to modulation of bruton's tyrosine kinase activity |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9233983B2 (instruction) |
| EP (1) | EP2838898B1 (instruction) |
| JP (1) | JP6182593B2 (instruction) |
| CN (1) | CN104662018B (instruction) |
| AU (1) | AU2013250726B2 (instruction) |
| CA (1) | CA2869954C (instruction) |
| IL (1) | IL235146A (instruction) |
| IN (1) | IN2012CH01573A (instruction) |
| WO (1) | WO2013157022A1 (instruction) |
| ZA (1) | ZA201407341B (instruction) |
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| WO2011146313A1 (en) | 2010-05-19 | 2011-11-24 | The University Of North Carolina At Chapel Hill | Pyrazolopyrimidine compounds for the treatment of cancer |
| BR112014007788A2 (pt) | 2011-10-03 | 2017-04-18 | Univ North Carolina Chapel Hill | compostos de pirrolopirimidina para tratamento do câncer |
| IN2014DN09610A (instruction) | 2012-05-22 | 2015-07-31 | Univ North Carolina | |
| CA2881519A1 (en) | 2012-08-10 | 2014-02-13 | Boehringer Ingelheim International Gmbh | Heteroaromatic compounds as bruton's tyrosine kinase (btk) inhibitors |
| US9562047B2 (en) | 2012-10-17 | 2017-02-07 | The University Of North Carolina At Chapel Hill | Pyrazolopyrimidine compounds for the treatment of cancer |
| WO2014085225A1 (en) | 2012-11-27 | 2014-06-05 | The University Of North Carolina At Chapel Hill | Pyrimidine compounds for the treatment of cancer |
| MX2015012896A (es) * | 2013-03-14 | 2016-06-02 | Abbvie Inc | Inhibidores de pirrolo [2,3-b] piridina cdk9 cinasa. |
| CN104211703B (zh) * | 2013-05-30 | 2018-04-03 | 南京勇山生物科技有限公司 | 一类作为布鲁顿激酶抑制剂的稠杂环化合物 |
| US9512084B2 (en) | 2013-11-29 | 2016-12-06 | Novartis Ag | Amino pyrimidine derivatives |
| US20150291609A1 (en) | 2014-04-11 | 2015-10-15 | The University Of North Carolina At Chapel Hill | Mertk-specific pyrimidine compounds |
| CN105294571B (zh) | 2014-07-03 | 2019-04-23 | 浙江九洲药业股份有限公司 | 一种依鲁替尼中间体及其制备方法和用途 |
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