CA2789738C - Immunoglobulin g fc region binding polypeptide - Google Patents

Immunoglobulin g fc region binding polypeptide Download PDF

Info

Publication number
CA2789738C
CA2789738C CA2789738A CA2789738A CA2789738C CA 2789738 C CA2789738 C CA 2789738C CA 2789738 A CA2789738 A CA 2789738A CA 2789738 A CA2789738 A CA 2789738A CA 2789738 C CA2789738 C CA 2789738C
Authority
CA
Canada
Prior art keywords
igg
binding
polypeptide
binding polypeptide
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2789738A
Other languages
English (en)
French (fr)
Other versions
CA2789738A1 (en
Inventor
Lars Abrahmsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytiva Bioprocess R&D AB
Original Assignee
Cytiva Bioprocess R&D AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytiva Bioprocess R&D AB filed Critical Cytiva Bioprocess R&D AB
Publication of CA2789738A1 publication Critical patent/CA2789738A1/en
Application granted granted Critical
Publication of CA2789738C publication Critical patent/CA2789738C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033—Membrane, sheet, cloth, pad, lamellar or mat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
CA2789738A 2010-03-08 2011-03-07 Immunoglobulin g fc region binding polypeptide Active CA2789738C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10155835.1 2010-03-08
EP10155835 2010-03-08
PCT/EP2011/053362 WO2011110515A1 (en) 2010-03-08 2011-03-07 Immunoglobulin g fc region binding polypeptide

Publications (2)

Publication Number Publication Date
CA2789738A1 CA2789738A1 (en) 2011-09-15
CA2789738C true CA2789738C (en) 2021-03-09

Family

ID=43927858

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2789738A Active CA2789738C (en) 2010-03-08 2011-03-07 Immunoglobulin g fc region binding polypeptide

Country Status (8)

Country Link
US (1) US9175067B2 (enExample)
EP (2) EP2977088B1 (enExample)
JP (1) JP5951509B2 (enExample)
CN (2) CN107686513A (enExample)
CA (1) CA2789738C (enExample)
DK (2) DK2977088T3 (enExample)
ES (1) ES2641896T3 (enExample)
WO (1) WO2011110515A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120165650A1 (en) * 2010-12-22 2012-06-28 General Electric Company Her2 binders
WO2015189431A1 (en) * 2014-06-13 2015-12-17 Affibody Ab New polypeptide
WO2015189430A1 (en) * 2014-06-13 2015-12-17 Affibody Ab New polypeptide
ES2977457T3 (es) * 2014-12-17 2024-08-23 Cytiva Bioprocess R & D Ab Polipéptidos de unión a la cadena ligera kappa modificados
KR20240110106A (ko) * 2015-01-12 2024-07-12 애피바디 에이비 Il-17a-결합 폴리펩티드
WO2017054033A1 (en) * 2015-10-02 2017-04-06 The Macfarlane Burnet Institute For Medical Research And Public Health Ltd Binding assays and method for probing antibody function with fc binding multimers
US11008365B2 (en) 2016-09-01 2021-05-18 National Institute Of Advanced Industrial Science And Technology Polypeptide exhibiting affinity to antibodies forming non-native three-dimensional structure
UY37651A (es) * 2017-03-31 2018-10-31 Swedish Orphan Biovitrum Ab Publ Polipéptido de unión al il-1r-i
GB201717446D0 (en) 2017-10-24 2017-12-06 Evox Therapeutics Ltd Affinity purification of engineering extracellular vesicles
EP3708667B1 (en) * 2017-11-09 2025-01-01 Tosoh Corporation Immunoglobulin-binding protein
AU2019380620B2 (en) * 2018-11-12 2022-05-26 Navigo Proteins Gmbh Novel triple-helical polypeptides lacking binding affinity for the Fc domain of immunoglobulin and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8505922D0 (sv) * 1985-12-13 1985-12-13 Kabigen Ab Construction of an igg binding protein to facilitate downstream processing using protein engineering
US7709209B2 (en) * 2002-03-25 2010-05-04 Ge Healthcare Bio-Sciences Ab Protein ligands
US20050147962A1 (en) 2002-11-19 2005-07-07 Wagstrom Christopher R. Display of dimeric proteins on phage
BRPI0406605B8 (pt) * 2003-11-13 2021-05-25 Hanmi Holdings Co Ltd conjugado de proteína, método para a preparação do mesmo e composição farmacêutica para intensificar a duração e estabilidade in vivo de um polipeptídeo fisiologicamente ativo
DE08786222T1 (de) * 2007-07-31 2010-11-25 Affibody Ab Neue albuminbindende zusammensetzungen, verfahren und anwendungen
EP2077272A1 (en) * 2007-12-21 2009-07-08 Affibody AB Polypeptide libraries with a predetermined scaffold
EP2072525A1 (en) * 2007-12-21 2009-06-24 Affibody AB New polypeptides having affinity for HER2
US9238810B2 (en) 2008-06-05 2016-01-19 Affibody Ab Polypeptide

Also Published As

Publication number Publication date
EP2977088B1 (en) 2017-08-02
DK2977088T3 (en) 2017-10-09
CA2789738A1 (en) 2011-09-15
EP2977088A1 (en) 2016-01-27
US20130203962A1 (en) 2013-08-08
CN107686513A (zh) 2018-02-13
ES2641896T3 (es) 2017-11-14
JP2013528567A (ja) 2013-07-11
EP2544785B1 (en) 2015-09-30
JP5951509B2 (ja) 2016-07-13
US9175067B2 (en) 2015-11-03
WO2011110515A1 (en) 2011-09-15
CN102811782A (zh) 2012-12-05
EP2544785A1 (en) 2013-01-16
DK2544785T3 (en) 2016-01-18

Similar Documents

Publication Publication Date Title
EP2544785B1 (en) Immunoglobulin g fc region binding polypeptide
EP2495253B1 (en) Novel immunoglobulin-binding proteins with improved specificity
JP6856938B2 (ja) 新規な免疫グロブリン結合タンパク質およびアフィニティ精製におけるそれらの使用
JP6184463B2 (ja) 免疫グロブリンに親和性を有するタンパク質および免疫グロブリン結合性アフィニティーリガンド
CN109071616B (zh) 链霉亲和素突变蛋白及其使用方法
EP2288617B1 (en) Polypeptide
CN121914229A (zh) 突变的免疫球蛋白-结合多肽
CA2891820A1 (en) Streptavidin muteins and methods of using them
CN102892885B (zh) IgA结合性肽以及利用其的IgA的纯化
WO2012133342A1 (ja) 免疫グロブリン結合性新規ポリペプチド
JP2013528567A5 (enExample)
US20180170973A1 (en) Immunoglobulin-binding modified protein
WO2019187602A1 (ja) 改変型免疫グロブリンκ鎖可変領域結合性ペプチド
SG190913A1 (en) Modified tamavidin
JPWO2018180205A1 (ja) 免疫グロブリン精製用アフィニティー分離マトリックス
US20230212218A1 (en) Novel immunoglobulin binding polypeptides
CN121449700A (zh) 一种免疫球蛋白结合蛋白及其应用
WO2019187603A1 (ja) 免疫グロブリンｇ結合性ペプチド

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20160209

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 14TH ANNIV.) - STANDARD

Year of fee payment: 14

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250211

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20250211

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250211

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 15TH ANNIV.) - STANDARD

Year of fee payment: 15

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20260210

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20260210