ES2641896T3 - Polipéptido de unión a la región Fc de la inmunoglobulina G - Google Patents
Polipéptido de unión a la región Fc de la inmunoglobulina G Download PDFInfo
- Publication number
- ES2641896T3 ES2641896T3 ES15181524.8T ES15181524T ES2641896T3 ES 2641896 T3 ES2641896 T3 ES 2641896T3 ES 15181524 T ES15181524 T ES 15181524T ES 2641896 T3 ES2641896 T3 ES 2641896T3
- Authority
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- Spain
- Prior art keywords
- igg
- amino acid
- binding
- polypeptide
- binding polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
- B01J20/28033—Membrane, sheet, cloth, pad, lamellar or mat
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/282—Porous sorbents
- B01J20/285—Porous sorbents based on polymers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
- B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10155835 | 2010-03-08 | ||
| EP10155835 | 2010-03-08 |
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|---|---|
| ES2641896T3 true ES2641896T3 (es) | 2017-11-14 |
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| ES15181524.8T Active ES2641896T3 (es) | 2010-03-08 | 2011-03-07 | Polipéptido de unión a la región Fc de la inmunoglobulina G |
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| US (1) | US9175067B2 (enExample) |
| EP (2) | EP2544785B1 (enExample) |
| JP (1) | JP5951509B2 (enExample) |
| CN (2) | CN102811782A (enExample) |
| CA (1) | CA2789738C (enExample) |
| DK (2) | DK2977088T3 (enExample) |
| ES (1) | ES2641896T3 (enExample) |
| WO (1) | WO2011110515A1 (enExample) |
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| US20120165650A1 (en) | 2010-12-22 | 2012-06-28 | General Electric Company | Her2 binders |
| EP3154564B1 (en) | 2014-06-13 | 2019-08-21 | Affibody AB | New polypeptide |
| KR102399024B1 (ko) * | 2014-06-13 | 2022-05-17 | 애피바디 에이비 | 신규 폴리펩티드 |
| KR20240110106A (ko) * | 2015-01-12 | 2024-07-12 | 애피바디 에이비 | Il-17a-결합 폴리펩티드 |
| EP3356829A4 (en) * | 2015-10-02 | 2019-02-27 | The Macfarlane Burnet Institute For Medical Research And Public Health Ltd | BINDING TESTS AND METHOD FOR PROBING ANTIBODY FUNCTION WITH FC BINDING MULTIMES |
| US11008365B2 (en) | 2016-09-01 | 2021-05-18 | National Institute Of Advanced Industrial Science And Technology | Polypeptide exhibiting affinity to antibodies forming non-native three-dimensional structure |
| UY37651A (es) | 2017-03-31 | 2018-10-31 | Swedish Orphan Biovitrum Ab Publ | Polipéptido de unión al il-1r-i |
| GB201717446D0 (en) | 2017-10-24 | 2017-12-06 | Evox Therapeutics Ltd | Affinity purification of engineering extracellular vesicles |
| EP3708667B1 (en) * | 2017-11-09 | 2025-01-01 | Tosoh Corporation | Immunoglobulin-binding protein |
| EP4349853A3 (en) * | 2018-11-12 | 2024-07-03 | Navigo Proteins Gmbh | Novel triple-helical polypeptides lacking binding affinity for the fc domain of immunoglobulin and uses thereof |
Family Cites Families (8)
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| SE8505922D0 (sv) * | 1985-12-13 | 1985-12-13 | Kabigen Ab | Construction of an igg binding protein to facilitate downstream processing using protein engineering |
| US7709209B2 (en) * | 2002-03-25 | 2010-05-04 | Ge Healthcare Bio-Sciences Ab | Protein ligands |
| US20050147962A1 (en) | 2002-11-19 | 2005-07-07 | Wagstrom Christopher R. | Display of dimeric proteins on phage |
| BRPI0406606A (pt) * | 2003-11-13 | 2005-12-06 | Hanmi Pharm Ind Co Ltd | Composição farmacêutica compreendendo uma região fc de imunoglobulina como um veìculo |
| DE08786222T1 (de) * | 2007-07-31 | 2010-11-25 | Affibody Ab | Neue albuminbindende zusammensetzungen, verfahren und anwendungen |
| EP2077272A1 (en) | 2007-12-21 | 2009-07-08 | Affibody AB | Polypeptide libraries with a predetermined scaffold |
| EP2072525A1 (en) * | 2007-12-21 | 2009-06-24 | Affibody AB | New polypeptides having affinity for HER2 |
| JP5677943B2 (ja) | 2008-06-05 | 2015-02-25 | アフィボディ・アーベーＡｆｆｉｂｏｄｙ Ａｂ | ポリペプチド |
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2011
- 2011-03-07 EP EP11707162.1A patent/EP2544785B1/en active Active
- 2011-03-07 DK DK15181524.8T patent/DK2977088T3/en active
- 2011-03-07 CA CA2789738A patent/CA2789738C/en active Active
- 2011-03-07 JP JP2012556471A patent/JP5951509B2/ja active Active
- 2011-03-07 ES ES15181524.8T patent/ES2641896T3/es active Active
- 2011-03-07 CN CN2011800128442A patent/CN102811782A/zh active Pending
- 2011-03-07 DK DK11707162.1T patent/DK2544785T3/en active
- 2011-03-07 WO PCT/EP2011/053362 patent/WO2011110515A1/en not_active Ceased
- 2011-03-07 CN CN201710866126.0A patent/CN107686513A/zh active Pending
- 2011-03-07 US US13/583,686 patent/US9175067B2/en active Active
- 2011-03-07 EP EP15181524.8A patent/EP2977088B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013528567A (ja) | 2013-07-11 |
| US20130203962A1 (en) | 2013-08-08 |
| US9175067B2 (en) | 2015-11-03 |
| EP2544785A1 (en) | 2013-01-16 |
| CA2789738A1 (en) | 2011-09-15 |
| DK2977088T3 (en) | 2017-10-09 |
| EP2977088A1 (en) | 2016-01-27 |
| JP5951509B2 (ja) | 2016-07-13 |
| EP2977088B1 (en) | 2017-08-02 |
| CN102811782A (zh) | 2012-12-05 |
| DK2544785T3 (en) | 2016-01-18 |
| WO2011110515A1 (en) | 2011-09-15 |
| CN107686513A (zh) | 2018-02-13 |
| CA2789738C (en) | 2021-03-09 |
| EP2544785B1 (en) | 2015-09-30 |
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