CN102811782A - 免疫球蛋白G Fc区结合多肽 - Google Patents

免疫球蛋白G Fc区结合多肽 Download PDF

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Publication number
CN102811782A
CN102811782A CN2011800128442A CN201180012844A CN102811782A CN 102811782 A CN102811782 A CN 102811782A CN 2011800128442 A CN2011800128442 A CN 2011800128442A CN 201180012844 A CN201180012844 A CN 201180012844A CN 102811782 A CN102811782 A CN 102811782A
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CN
China
Prior art keywords
polypeptide
igg
combines
amino acid
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011800128442A
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English (en)
Chinese (zh)
Inventor
L.阿布拉姆森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
Original Assignee
GE Healthcare Bio Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Bio Sciences Corp filed Critical GE Healthcare Bio Sciences Corp
Priority to CN201710866126.0A priority Critical patent/CN107686513A/zh
Publication of CN102811782A publication Critical patent/CN102811782A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033—Membrane, sheet, cloth, pad, lamellar or mat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
CN2011800128442A 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽 Pending CN102811782A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710866126.0A CN107686513A (zh) 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10155835.1 2010-03-08
EP10155835 2010-03-08
PCT/EP2011/053362 WO2011110515A1 (en) 2010-03-08 2011-03-07 Immunoglobulin g fc region binding polypeptide

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201710866126.0A Division CN107686513A (zh) 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽

Publications (1)

Publication Number Publication Date
CN102811782A true CN102811782A (zh) 2012-12-05

Family

ID=43927858

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2011800128442A Pending CN102811782A (zh) 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽
CN201710866126.0A Pending CN107686513A (zh) 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201710866126.0A Pending CN107686513A (zh) 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽

Country Status (8)

Country Link
US (1) US9175067B2 (enExample)
EP (2) EP2544785B1 (enExample)
JP (1) JP5951509B2 (enExample)
CN (2) CN102811782A (enExample)
CA (1) CA2789738C (enExample)
DK (2) DK2977088T3 (enExample)
ES (1) ES2641896T3 (enExample)
WO (1) WO2011110515A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111315887A (zh) * 2017-11-09 2020-06-19 东曹株式会社 免疫球蛋白结合性蛋白质
CN111344012A (zh) * 2017-10-24 2020-06-26 医福斯治疗有限公司 工程改造的细胞外囊泡的亲和纯化
CN112969708A (zh) * 2018-11-12 2021-06-15 纳维格蛋白质有限公司 缺乏免疫球蛋白fc结构域结合亲和力的新三螺旋多肽及其用途

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120165650A1 (en) 2010-12-22 2012-06-28 General Electric Company Her2 binders
EP3154564B1 (en) 2014-06-13 2019-08-21 Affibody AB New polypeptide
KR102399024B1 (ko) * 2014-06-13 2022-05-17 애피바디 에이비 신규 폴리펩티드
KR20240110106A (ko) * 2015-01-12 2024-07-12 애피바디 에이비 Il-17a-결합 폴리펩티드
EP3356829A4 (en) * 2015-10-02 2019-02-27 The Macfarlane Burnet Institute For Medical Research And Public Health Ltd BINDING TESTS AND METHOD FOR PROBING ANTIBODY FUNCTION WITH FC BINDING MULTIMES
US11008365B2 (en) 2016-09-01 2021-05-18 National Institute Of Advanced Industrial Science And Technology Polypeptide exhibiting affinity to antibodies forming non-native three-dimensional structure
UY37651A (es) 2017-03-31 2018-10-31 Swedish Orphan Biovitrum Ab Publ Polipéptido de unión al il-1r-i

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143844A (en) * 1985-12-13 1992-09-01 Kabigen Ab Construction of an igg binding protein to facilitate downstream processing using protein engineering
WO2009016043A2 (en) * 2007-07-31 2009-02-05 Affibody Ab New albumin binding compositions, methods and uses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7709209B2 (en) * 2002-03-25 2010-05-04 Ge Healthcare Bio-Sciences Ab Protein ligands
US20050147962A1 (en) 2002-11-19 2005-07-07 Wagstrom Christopher R. Display of dimeric proteins on phage
BRPI0406606A (pt) * 2003-11-13 2005-12-06 Hanmi Pharm Ind Co Ltd Composição farmacêutica compreendendo uma região fc de imunoglobulina como um veìculo
EP2077272A1 (en) 2007-12-21 2009-07-08 Affibody AB Polypeptide libraries with a predetermined scaffold
EP2072525A1 (en) * 2007-12-21 2009-06-24 Affibody AB New polypeptides having affinity for HER2
JP5677943B2 (ja) 2008-06-05 2015-02-25 アフィボディ・アーベーＡｆｆｉｂｏｄｙ Ａｂ ポリペプチド

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143844A (en) * 1985-12-13 1992-09-01 Kabigen Ab Construction of an igg binding protein to facilitate downstream processing using protein engineering
WO2009016043A2 (en) * 2007-07-31 2009-02-05 Affibody Ab New albumin binding compositions, methods and uses

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
徐容等: "噬菌体展示protein A及protein L Ig结合单结构域随机组合文库及Ig亲和筛选", 《生物化学与生物物理进展》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111344012A (zh) * 2017-10-24 2020-06-26 医福斯治疗有限公司 工程改造的细胞外囊泡的亲和纯化
CN111344012B (zh) * 2017-10-24 2023-12-22 医福斯治疗有限公司 工程改造的细胞外囊泡的亲和纯化
US11975070B2 (en) 2017-10-24 2024-05-07 Evox Therapeutics Ltd Affinity purification of engineered extracellular vesicles
CN111315887A (zh) * 2017-11-09 2020-06-19 东曹株式会社 免疫球蛋白结合性蛋白质
CN111315887B (zh) * 2017-11-09 2024-02-06 东曹株式会社 免疫球蛋白结合性蛋白质
CN112969708A (zh) * 2018-11-12 2021-06-15 纳维格蛋白质有限公司 缺乏免疫球蛋白fc结构域结合亲和力的新三螺旋多肽及其用途

Also Published As

Publication number Publication date
JP2013528567A (ja) 2013-07-11
US20130203962A1 (en) 2013-08-08
US9175067B2 (en) 2015-11-03
EP2544785A1 (en) 2013-01-16
ES2641896T3 (es) 2017-11-14
CA2789738A1 (en) 2011-09-15
DK2977088T3 (en) 2017-10-09
EP2977088A1 (en) 2016-01-27
JP5951509B2 (ja) 2016-07-13
EP2977088B1 (en) 2017-08-02
DK2544785T3 (en) 2016-01-18
WO2011110515A1 (en) 2011-09-15
CN107686513A (zh) 2018-02-13
CA2789738C (en) 2021-03-09
EP2544785B1 (en) 2015-09-30

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SE01 Entry into force of request for substantive examination
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Effective date of registration: 20160824

Address after: uppsala

Applicant after: GE HEALTHCARE BIO-SCIENCES AB

Address before: uppsala

Applicant before: GE Health Bio-science Co., Ltd.

RJ01 Rejection of invention patent application after publication

Application publication date: 20121205

RJ01 Rejection of invention patent application after publication