DK2544785T3 - Immunoglobulin G Fc region binding polypeptide - Google Patents

Immunoglobulin G Fc region binding polypeptide Download PDF

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Publication number
DK2544785T3
DK2544785T3 DK11707162.1T DK11707162T DK2544785T3 DK 2544785 T3 DK2544785 T3 DK 2544785T3 DK 11707162 T DK11707162 T DK 11707162T DK 2544785 T3 DK2544785 T3 DK 2544785T3
Authority
DK
Denmark
Prior art keywords
amino acid
polypeptide
igg
binding
leu
Prior art date
Application number
DK11707162.1T
Other languages
Danish (da)
English (en)
Inventor
Lars Abrahmsén
Original Assignee
Ge Healthcare Bio Sciences Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Bio Sciences Ab filed Critical Ge Healthcare Bio Sciences Ab
Application granted granted Critical
Publication of DK2544785T3 publication Critical patent/DK2544785T3/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033—Membrane, sheet, cloth, pad, lamellar or mat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK11707162.1T 2010-03-08 2011-03-07 Immunoglobulin G Fc region binding polypeptide DK2544785T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10155835 2010-03-08
PCT/EP2011/053362 WO2011110515A1 (en) 2010-03-08 2011-03-07 Immunoglobulin g fc region binding polypeptide

Publications (1)

Publication Number Publication Date
DK2544785T3 true DK2544785T3 (en) 2016-01-18

Family

ID=43927858

Family Applications (2)

Application Number Title Priority Date Filing Date
DK11707162.1T DK2544785T3 (en) 2010-03-08 2011-03-07 Immunoglobulin G Fc region binding polypeptide
DK15181524.8T DK2977088T3 (en) 2010-03-08 2011-03-07 IMMUNOGLOBULIN G FC REGION BINDING POLYPEPTIDE

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK15181524.8T DK2977088T3 (en) 2010-03-08 2011-03-07 IMMUNOGLOBULIN G FC REGION BINDING POLYPEPTIDE

Country Status (8)

Country Link
US (1) US9175067B2 (enExample)
EP (2) EP2544785B1 (enExample)
JP (1) JP5951509B2 (enExample)
CN (2) CN102811782A (enExample)
CA (1) CA2789738C (enExample)
DK (2) DK2544785T3 (enExample)
ES (1) ES2641896T3 (enExample)
WO (1) WO2011110515A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120165650A1 (en) 2010-12-22 2012-06-28 General Electric Company Her2 binders
WO2015189431A1 (en) * 2014-06-13 2015-12-17 Affibody Ab New polypeptide
US10669314B2 (en) 2014-06-13 2020-06-02 Affibody Ab Polypeptide
WO2016113246A1 (en) 2015-01-12 2016-07-21 Affibody Ab Il-17a-binding polypeptides
US20180284130A1 (en) * 2015-10-02 2018-10-04 The Macfarlane Burnet Institute For Medical Research And Publichealth Ltd Binding assays and method for probing antibody function with fc binding multimers
JP6818305B2 (ja) * 2016-09-01 2021-01-20 国立研究開発法人産業技術総合研究所 非天然型立体構造を形成した抗体に親和性を示すポリペプチド
UY37651A (es) * 2017-03-31 2018-10-31 Swedish Orphan Biovitrum Ab Publ Polipéptido de unión al il-1r-i
GB201717446D0 (en) * 2017-10-24 2017-12-06 Evox Therapeutics Ltd Affinity purification of engineering extracellular vesicles
JP7306270B2 (ja) * 2017-11-09 2023-07-11 東ソー株式会社 免疫グロブリン結合性タンパク質
JP7591284B2 (ja) * 2018-11-12 2024-11-28 ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツング 免疫グロブリンＦｃドメインに対する結合親和性を持たない新規三重らせんポリペプチド及び同ポリペプチドの使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8505922D0 (sv) * 1985-12-13 1985-12-13 Kabigen Ab Construction of an igg binding protein to facilitate downstream processing using protein engineering
US7709209B2 (en) * 2002-03-25 2010-05-04 Ge Healthcare Bio-Sciences Ab Protein ligands
US20050147962A1 (en) * 2002-11-19 2005-07-07 Wagstrom Christopher R. Display of dimeric proteins on phage
EP2239273B1 (en) * 2003-11-13 2013-10-09 Hanmi Science Co., Ltd. A pharmaceutical composition comprosing an immunoglobulin fc as a carrier
CN104710518A (zh) * 2007-07-31 2015-06-17 阿菲博迪公司 新白蛋白结合组合物、方法及应用
EP2077272A1 (en) 2007-12-21 2009-07-08 Affibody AB Polypeptide libraries with a predetermined scaffold
EP2072525A1 (en) * 2007-12-21 2009-06-24 Affibody AB New polypeptides having affinity for HER2
US9238810B2 (en) * 2008-06-05 2016-01-19 Affibody Ab Polypeptide

Also Published As

Publication number Publication date
EP2977088B1 (en) 2017-08-02
EP2977088A1 (en) 2016-01-27
US20130203962A1 (en) 2013-08-08
US9175067B2 (en) 2015-11-03
CA2789738C (en) 2021-03-09
EP2544785A1 (en) 2013-01-16
CA2789738A1 (en) 2011-09-15
CN102811782A (zh) 2012-12-05
JP2013528567A (ja) 2013-07-11
JP5951509B2 (ja) 2016-07-13
CN107686513A (zh) 2018-02-13
WO2011110515A1 (en) 2011-09-15
ES2641896T3 (es) 2017-11-14
EP2544785B1 (en) 2015-09-30
DK2977088T3 (en) 2017-10-09

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