DK2977088T3 - IMMUNOGLOBULIN G FC REGION BINDING POLYPEPTIDE - Google Patents

IMMUNOGLOBULIN G FC REGION BINDING POLYPEPTIDE Download PDF

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Publication number
DK2977088T3
DK2977088T3 DK15181524.8T DK15181524T DK2977088T3 DK 2977088 T3 DK2977088 T3 DK 2977088T3 DK 15181524 T DK15181524 T DK 15181524T DK 2977088 T3 DK2977088 T3 DK 2977088T3
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DK
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Prior art keywords
igg
amino acid
binding
polypeptide
binding polypeptide
Prior art date
Application number
DK15181524.8T
Other languages
Danish (da)
English (en)
Inventor
Lars Abrahmsén
Original Assignee
Ge Healthcare Bioprocess R&D Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Bioprocess R&D Ab filed Critical Ge Healthcare Bioprocess R&D Ab
Application granted granted Critical
Publication of DK2977088T3 publication Critical patent/DK2977088T3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804Affinity chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804Affinity chromatography
    • B01D15/3809Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033Membrane, sheet, cloth, pad, lamellar or mat
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282Porous sorbents
    • B01J20/285Porous sorbents based on polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/3272Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DK15181524.8T 2010-03-08 2011-03-07 IMMUNOGLOBULIN G FC REGION BINDING POLYPEPTIDE DK2977088T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10155835 2010-03-08
EP11707162.1A EP2544785B1 (en) 2010-03-08 2011-03-07 Immunoglobulin g fc region binding polypeptide

Publications (1)

Publication Number Publication Date
DK2977088T3 true DK2977088T3 (en) 2017-10-09

Family

ID=43927858

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15181524.8T DK2977088T3 (en) 2010-03-08 2011-03-07 IMMUNOGLOBULIN G FC REGION BINDING POLYPEPTIDE
DK11707162.1T DK2544785T3 (en) 2010-03-08 2011-03-07 Immunoglobulin G Fc region binding polypeptide

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK11707162.1T DK2544785T3 (en) 2010-03-08 2011-03-07 Immunoglobulin G Fc region binding polypeptide

Country Status (8)

Country Link
US (1) US9175067B2 (enExample)
EP (2) EP2544785B1 (enExample)
JP (1) JP5951509B2 (enExample)
CN (2) CN102811782A (enExample)
CA (1) CA2789738C (enExample)
DK (2) DK2977088T3 (enExample)
ES (1) ES2641896T3 (enExample)
WO (1) WO2011110515A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120165650A1 (en) 2010-12-22 2012-06-28 General Electric Company Her2 binders
EP3154564B1 (en) 2014-06-13 2019-08-21 Affibody AB New polypeptide
KR102399024B1 (ko) * 2014-06-13 2022-05-17 애피바디 에이비 신규 폴리펩티드
KR20240110106A (ko) * 2015-01-12 2024-07-12 애피바디 에이비 Il-17a-결합 폴리펩티드
EP3356829A4 (en) * 2015-10-02 2019-02-27 The Macfarlane Burnet Institute For Medical Research And Public Health Ltd BINDING TESTS AND METHOD FOR PROBING ANTIBODY FUNCTION WITH FC BINDING MULTIMES
US11008365B2 (en) 2016-09-01 2021-05-18 National Institute Of Advanced Industrial Science And Technology Polypeptide exhibiting affinity to antibodies forming non-native three-dimensional structure
UY37651A (es) 2017-03-31 2018-10-31 Swedish Orphan Biovitrum Ab Publ Polipéptido de unión al il-1r-i
GB201717446D0 (en) 2017-10-24 2017-12-06 Evox Therapeutics Ltd Affinity purification of engineering extracellular vesicles
EP3708667B1 (en) * 2017-11-09 2025-01-01 Tosoh Corporation Immunoglobulin-binding protein
EP4349853A3 (en) * 2018-11-12 2024-07-03 Navigo Proteins Gmbh Novel triple-helical polypeptides lacking binding affinity for the fc domain of immunoglobulin and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8505922D0 (sv) * 1985-12-13 1985-12-13 Kabigen Ab Construction of an igg binding protein to facilitate downstream processing using protein engineering
US7709209B2 (en) * 2002-03-25 2010-05-04 Ge Healthcare Bio-Sciences Ab Protein ligands
US20050147962A1 (en) 2002-11-19 2005-07-07 Wagstrom Christopher R. Display of dimeric proteins on phage
BRPI0406606A (pt) * 2003-11-13 2005-12-06 Hanmi Pharm Ind Co Ltd Composição farmacêutica compreendendo uma região fc de imunoglobulina como um veìculo
DE08786222T1 (de) * 2007-07-31 2010-11-25 Affibody Ab Neue albuminbindende zusammensetzungen, verfahren und anwendungen
EP2077272A1 (en) 2007-12-21 2009-07-08 Affibody AB Polypeptide libraries with a predetermined scaffold
EP2072525A1 (en) * 2007-12-21 2009-06-24 Affibody AB New polypeptides having affinity for HER2
JP5677943B2 (ja) 2008-06-05 2015-02-25 アフィボディ・アーベーAffibody Ab ポリペプチド

Also Published As

Publication number Publication date
JP2013528567A (ja) 2013-07-11
US20130203962A1 (en) 2013-08-08
US9175067B2 (en) 2015-11-03
EP2544785A1 (en) 2013-01-16
ES2641896T3 (es) 2017-11-14
CA2789738A1 (en) 2011-09-15
EP2977088A1 (en) 2016-01-27
JP5951509B2 (ja) 2016-07-13
EP2977088B1 (en) 2017-08-02
CN102811782A (zh) 2012-12-05
DK2544785T3 (en) 2016-01-18
WO2011110515A1 (en) 2011-09-15
CN107686513A (zh) 2018-02-13
CA2789738C (en) 2021-03-09
EP2544785B1 (en) 2015-09-30

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