CA2693081A1 - Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique - Google Patents
Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique Download PDFInfo
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- CA2693081A1 CA2693081A1 CA2693081A CA2693081A CA2693081A1 CA 2693081 A1 CA2693081 A1 CA 2693081A1 CA 2693081 A CA2693081 A CA 2693081A CA 2693081 A CA2693081 A CA 2693081A CA 2693081 A1 CA2693081 A1 CA 2693081A1
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract
Cette invention, selon des modes de réalisation, porte sur des procédés, des systèmes et un appareil pour déterminer si une aneuploïdie chromosomique foetale existe à partir d'un échantillon biologique obtenu auprès d'une femme enceinte. Des molécules d'acide nucléique de l'échantillon biologique sont séquencées, de telle sorte qu'une fraction du génome est séquencée. Des quantités respectives d'un chromosome cliniquement pertinent et de chromosomes de fond sont déterminées à partir des résultats du séquençage. Un paramètre issu de ces quantités (par exemple, un rapport) est comparé à une ou à plusieurs valeurs limites, permettant ainsi de déterminer une classification quant à l'existence d'une aneuploïdie chromosomique ftale.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2900927A CA2900927C (fr) | 2007-07-23 | 2008-07-23 | Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95143807P | 2007-07-23 | 2007-07-23 | |
US60/951,438 | 2007-07-23 | ||
PCT/GB2008/002530 WO2009013496A1 (fr) | 2007-07-23 | 2008-07-23 | Diagnostic d'une aneuploïdie chromosomique fœtale à l'aide d'un séquençage génomique |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2900927A Division CA2900927C (fr) | 2007-07-23 | 2008-07-23 | Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2693081A1 true CA2693081A1 (fr) | 2009-01-29 |
CA2693081C CA2693081C (fr) | 2016-01-26 |
Family
ID=39798126
Family Applications (10)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3029497A Active CA3029497C (fr) | 2007-07-23 | 2008-07-23 | Determination d'un desequilibre de sequences d'acide nucleique |
CA3127930A Pending CA3127930A1 (fr) | 2007-07-23 | 2008-07-23 | Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique |
CA3076159A Active CA3076159C (fr) | 2007-07-23 | 2008-07-23 | Analyse d'adn tumoral dans un echantillon acellulaire |
CA3176319A Pending CA3176319A1 (fr) | 2007-07-23 | 2008-07-23 | Analyse d'adn tumoral dans un echantillon acellulaire |
CA2693081A Active CA2693081C (fr) | 2007-07-23 | 2008-07-23 | Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique |
CA3076142A Active CA3076142C (fr) | 2007-07-23 | 2008-07-23 | Analyse d'adn tumoral dans un echantillon acellulaire |
CA2900927A Active CA2900927C (fr) | 2007-07-23 | 2008-07-23 | Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique |
CA3009992A Active CA3009992C (fr) | 2007-07-23 | 2008-07-23 | Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique |
CA3200589A Pending CA3200589A1 (fr) | 2007-07-23 | 2008-07-23 | Determination d'un desequilibre de sequences d'acide nucleique |
CA2694007A Active CA2694007C (fr) | 2007-07-23 | 2008-07-23 | Determination d'un desequilibre de sequences d'acide nucleique |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3029497A Active CA3029497C (fr) | 2007-07-23 | 2008-07-23 | Determination d'un desequilibre de sequences d'acide nucleique |
CA3127930A Pending CA3127930A1 (fr) | 2007-07-23 | 2008-07-23 | Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique |
CA3076159A Active CA3076159C (fr) | 2007-07-23 | 2008-07-23 | Analyse d'adn tumoral dans un echantillon acellulaire |
CA3176319A Pending CA3176319A1 (fr) | 2007-07-23 | 2008-07-23 | Analyse d'adn tumoral dans un echantillon acellulaire |
Family Applications After (5)
Application Number | Title | Priority Date | Filing Date |
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CA2900927A Active CA2900927C (fr) | 2007-07-23 | 2008-07-23 | Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique |
CA3009992A Active CA3009992C (fr) | 2007-07-23 | 2008-07-23 | Diagnostic d'une aneuploidie chromosomique foetale a l'aide d'un sequencage genomique |
CA3200589A Pending CA3200589A1 (fr) | 2007-07-23 | 2008-07-23 | Determination d'un desequilibre de sequences d'acide nucleique |
CA2694007A Active CA2694007C (fr) | 2007-07-23 | 2008-07-23 | Determination d'un desequilibre de sequences d'acide nucleique |
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JP (16) | JP5519500B2 (fr) |
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US10662474B2 (en) | 2010-01-19 | 2020-05-26 | Verinata Health, Inc. | Identification of polymorphic sequences in mixtures of genomic DNA by whole genome sequencing |
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