CA2608965C - Dispositif d'analyse quantitative de profil de metabolite - Google Patents

Dispositif d'analyse quantitative de profil de metabolite Download PDF

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Publication number
CA2608965C
CA2608965C CA2608965A CA2608965A CA2608965C CA 2608965 C CA2608965 C CA 2608965C CA 2608965 A CA2608965 A CA 2608965A CA 2608965 A CA2608965 A CA 2608965A CA 2608965 C CA2608965 C CA 2608965C
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insert
sample
analysis
drug
biological sample
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CA2608965A
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CA2608965A1 (fr
Inventor
Steven Lewis Ramsay
Wolfgang Guggenbichler
Klaus Michael Weinberger
Armin Graber
Wolfgang Markus Stoeggl
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Biocrates Life Sciences AG
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Biocrates Life Sciences AG
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5038—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving detection of metabolites per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30—Data warehousing; Computing architectures
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Evolutionary Biology (AREA)
  • Databases & Information Systems (AREA)
  • Medical Informatics (AREA)
  • Bioethics (AREA)
  • Toxicology (AREA)
  • Quality & Reliability (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

L'invention concerne un dispositif, notamment un dispositif de préparation d'échantillon destiné à l'analyse quantitative d'un médicament et/ou d'un profil de métabolite dans un échantillon biologique. En outre, cette invention concerne un insert destiné à un tel dispositif imprimé d'au moins un standard interne, dans le standard interne lui-même, et un nécessaire comprenant le dispositif. Par ailleurs, cette invention concerne un appareil contenant ce dispositif, et un procédé destiné à l'analyse quantitative d'un médicament et/ou d'un profil de métabolite dans un échantillon biologique au moyen dudit dispositif.
CA2608965A 2005-06-30 2006-06-29 Dispositif d'analyse quantitative de profil de metabolite Active CA2608965C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US69498405P 2005-06-30 2005-06-30
US69498305P 2005-06-30 2005-06-30
US60/694,984 2005-06-30
US60/694,983 2005-06-30
PCT/EP2006/006328 WO2007003344A2 (fr) 2005-06-30 2006-06-29 Dispositif d'analyse quantitative de profil de metabolite

Publications (2)

Publication Number Publication Date
CA2608965A1 CA2608965A1 (fr) 2007-01-11
CA2608965C true CA2608965C (fr) 2014-08-19

Family

ID=36783737

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2608965A Active CA2608965C (fr) 2005-06-30 2006-06-29 Dispositif d'analyse quantitative de profil de metabolite
CA2608963A Active CA2608963C (fr) 2005-06-30 2006-06-29 Appareil et procede d'analyse d'un profil de metabolites

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2608963A Active CA2608963C (fr) 2005-06-30 2006-06-29 Appareil et procede d'analyse d'un profil de metabolites

Country Status (16)

Country Link
US (2) US8116983B2 (fr)
EP (2) EP1897014B1 (fr)
JP (2) JP5155160B2 (fr)
KR (1) KR100967573B1 (fr)
CN (1) CN100594501C (fr)
AU (1) AU2006265381B2 (fr)
BR (1) BRPI0613478B8 (fr)
CA (2) CA2608965C (fr)
DK (2) DK1897014T3 (fr)
ES (1) ES2452025T3 (fr)
IL (1) IL187470A (fr)
IN (1) IN2014DN02241A (fr)
NO (1) NO339319B1 (fr)
NZ (1) NZ563431A (fr)
RU (1) RU2391672C2 (fr)
WO (2) WO2007003344A2 (fr)

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EP1875401B1 (fr) 2014-03-05
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US20070003965A1 (en) 2007-01-04
KR20080025092A (ko) 2008-03-19
US8265877B2 (en) 2012-09-11
BRPI0613478A2 (pt) 2012-01-17
AU2006265381A1 (en) 2007-01-11
BRPI0613478B8 (pt) 2021-07-27
IN2014DN02241A (fr) 2015-07-10
WO2007003343A1 (fr) 2007-01-11
CN101208697A (zh) 2008-06-25
NO339319B1 (no) 2016-11-28
WO2007003344A3 (fr) 2007-04-26
IL187470A0 (en) 2008-03-20
CN100594501C (zh) 2010-03-17
JP5155160B2 (ja) 2013-02-27
US20070004044A1 (en) 2007-01-04
CA2608963A1 (fr) 2007-01-11
EP1875401A2 (fr) 2008-01-09
CA2608965A1 (fr) 2007-01-11
NO20080559L (no) 2008-01-30
JP2008547031A (ja) 2008-12-25
EP1897014A1 (fr) 2008-03-12
RU2391672C2 (ru) 2010-06-10
ES2452025T3 (es) 2014-03-31
DK1897014T3 (en) 2014-03-10
JP2008547030A (ja) 2008-12-25
BRPI0613478B1 (pt) 2019-07-09
JP4829297B2 (ja) 2011-12-07
IL187470A (en) 2015-02-26
CA2608963C (fr) 2014-08-26
KR100967573B1 (ko) 2010-07-05
US8116983B2 (en) 2012-02-14
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