CA2559408C - Carboline derivatives useful in the inhibition of angiogenesis - Google Patents
Carboline derivatives useful in the inhibition of angiogenesis Download PDFInfo
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- CA2559408C CA2559408C CA2559408A CA2559408A CA2559408C CA 2559408 C CA2559408 C CA 2559408C CA 2559408 A CA2559408 A CA 2559408A CA 2559408 A CA2559408 A CA 2559408A CA 2559408 C CA2559408 C CA 2559408C
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- compound
- optionally substituted
- alkyl
- alkoxy
- halogen
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Landscapes
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| US60/552,725 | 2004-03-15 | ||
| PCT/US2005/008481 WO2005089764A1 (en) | 2004-03-15 | 2005-03-15 | Carboline derivatives useful in the inhibition of angiogenesis |
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| CA2559408A1 CA2559408A1 (en) | 2005-09-29 |
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| US9068234B2 (en) | 2003-01-21 | 2015-06-30 | Ptc Therapeutics, Inc. | Methods and agents for screening for compounds capable of modulating gene expression |
| US8426194B2 (en) * | 2003-01-21 | 2013-04-23 | Ptc Therapeutics, Inc. | Methods and agents for screening for compounds capable of modulating VEGF expression |
| EP1604011A4 (en) | 2003-01-21 | 2009-12-09 | Ptc Therapeutics Inc | METHODS FOR IDENTIFYING COMPOUNDS THAT MODULATE THE EXPRESSION OF DEPENDENT GENES FROM A NON-TRANSLATED REGION, AND METHODS OF USING SAME |
| JP4671123B2 (ja) * | 2003-06-23 | 2011-04-13 | 小野薬品工業株式会社 | 新規三環性複素環化合物 |
| US7767689B2 (en) * | 2004-03-15 | 2010-08-03 | Ptc Therapeutics, Inc. | Carboline derivatives useful in the treatment of cancer |
| US8076353B2 (en) | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Inhibition of VEGF translation |
| US8076352B2 (en) * | 2004-03-15 | 2011-12-13 | Ptc Therapeutics, Inc. | Administration of carboline derivatives useful in the treatment of cancer and other diseases |
| PL1737461T3 (pl) | 2004-03-15 | 2013-05-31 | Ptc Therapeutics Inc | Pochodne karbolinowe użyteczne w hamowaniu angiogenezy |
| JP2008508356A (ja) * | 2004-08-02 | 2008-03-21 | スミスクライン ビーチャム コーポレーション | Ｈｐｖ感染に有用な化合物 |
| DK1829874T3 (da) | 2004-12-22 | 2014-05-12 | Ono Pharmaceutical Co | Tricyklisk forbindelse og anvendelse deraf |
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