CA2516291A1 - Forme de dosage presentant une matrice en saccharide - Google Patents

Forme de dosage presentant une matrice en saccharide Download PDF

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Publication number
CA2516291A1
CA2516291A1 CA002516291A CA2516291A CA2516291A1 CA 2516291 A1 CA2516291 A1 CA 2516291A1 CA 002516291 A CA002516291 A CA 002516291A CA 2516291 A CA2516291 A CA 2516291A CA 2516291 A1 CA2516291 A1 CA 2516291A1
Authority
CA
Canada
Prior art keywords
dosage form
allergen
form according
solid dosage
active substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002516291A
Other languages
English (en)
Other versions
CA2516291C (fr
Inventor
Christian Gauguin Houghton
Annette Roemmelmayer Lundegaard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALK Abello AS
Original Assignee
Alk-Abello A/S
Christian Gauguin Houghton
Annette Roemmelmayer Lundegaard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alk-Abello A/S, Christian Gauguin Houghton, Annette Roemmelmayer Lundegaard filed Critical Alk-Abello A/S
Publication of CA2516291A1 publication Critical patent/CA2516291A1/fr
Application granted granted Critical
Publication of CA2516291C publication Critical patent/CA2516291C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2516291A 2003-02-28 2004-02-24 Forme de dosage presentant une matrice en saccharide Expired - Fee Related CA2516291C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200300318 2003-02-28
DKPA200300318 2003-02-28
US46538303P 2003-04-25 2003-04-25
US60/465,383 2003-04-25
PCT/DK2004/000119 WO2004075875A1 (fr) 2003-02-28 2004-02-24 Forme de dosage presentant une matrice en saccharide

Publications (2)

Publication Number Publication Date
CA2516291A1 true CA2516291A1 (fr) 2004-09-10
CA2516291C CA2516291C (fr) 2012-02-14

Family

ID=32929063

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2516291A Expired - Fee Related CA2516291C (fr) 2003-02-28 2004-02-24 Forme de dosage presentant une matrice en saccharide

Country Status (9)

Country Link
EP (1) EP1599185A1 (fr)
JP (1) JP4688787B2 (fr)
KR (1) KR101136573B1 (fr)
AU (1) AU2004216559B2 (fr)
CA (1) CA2516291C (fr)
HK (1) HK1089083A1 (fr)
MX (1) MXPA05009079A (fr)
PL (1) PL210707B1 (fr)
WO (1) WO2004075875A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9731018B2 (en) 2011-09-16 2017-08-15 Ferring B.V. Fast dissolving pharmaceutical composition
US10023335B2 (en) 2010-03-29 2018-07-17 Ferring B.V. Fast dissolving pharmaceutical composition
US10086078B2 (en) 2010-03-29 2018-10-02 Ferring B.V. Fast dissolving pharmaceutical composition

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060210590A1 (en) 2005-02-03 2006-09-21 Alk-Abello A/S Minor allergen control to increase safety of immunotherapy
AU2006299310A1 (en) 2005-10-04 2007-04-12 Alk-Abello A/S Solid vaccine formulation
PL2493457T3 (pl) 2009-10-30 2018-01-31 Ix Biopharma Ltd Szybko rozpuszczalna stała postać dawkowana
JP5800527B2 (ja) * 2010-03-30 2015-10-28 日東電工株式会社 安定化医薬組成物、安定化医薬組成物溶液製剤、フィルム状製剤及びフィルム状製剤の製造方法
MY164204A (en) * 2010-11-04 2017-11-30 Norgine Bv Formulations comprising polyethylene glycol
JP2012240975A (ja) * 2011-05-20 2012-12-10 Nitto Denko Corp 医薬組成物及びゼリー状製剤
JP2012240978A (ja) * 2011-05-20 2012-12-10 Nitto Denko Corp 医薬組成物及びゼリー状製剤
ES2940686T3 (es) * 2013-03-14 2023-05-10 Nestle Sa Fabricación de formulaciones de cacahuete para la desensibilización oral
EP2952200A1 (fr) 2014-06-04 2015-12-09 Alk-Abelló A/S Allergène pour le traitement prophylactique d'une allergie
GB2545880A (en) 2015-10-20 2017-07-05 Glide Pharmaceutical Tech Ltd Solid formulation
CN111432804A (zh) * 2017-11-27 2020-07-17 帝斯曼知识产权资产管理有限公司 冻干的多微粒固体剂型
JP6592791B1 (ja) * 2018-01-29 2019-10-23 株式会社リタファーマ 医薬製剤及びその製造方法
CN113966229A (zh) 2019-05-10 2022-01-21 爱沐疗法公司 用于改善花生过敏患者的生活质量的方法
CN116891827B (zh) * 2023-09-08 2024-01-30 山东康华生物医疗科技股份有限公司 一种nk细胞活性激活体系

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD107208A1 (fr) 1973-06-04 1974-07-20
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
FR2609895B1 (fr) 1987-01-28 1991-06-28 Bruttmann Georges Nouvelles formes galeniques d'allergenes pour administration par voie per- et sub-linguale
US5558880A (en) 1989-12-22 1996-09-24 Janssen Pharmaceutica Inc. Pharmaceutical and other dosage forms
US5215756A (en) 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
US6337082B1 (en) 1991-10-25 2002-01-08 Biovail Tech Ltd Saccharide-based matrix
US5343762A (en) 1992-10-05 1994-09-06 Rosemount Inc. Vortex flowmeter
US5343672A (en) 1992-12-01 1994-09-06 Scherer Ltd R P Method for manufacturing freeze dried dosages in a multilaminate blister pack
BR9405996A (pt) * 1993-03-11 1995-12-19 Secretech Inc Mucoadesivos poliméricos na distribuição de imunógenos em superfícies mucosais
US6010719A (en) * 1997-09-16 2000-01-04 Universiteit Gent Freeze-dried disintegrating tablets
GB9722682D0 (en) * 1997-10-27 1997-12-24 Scherer Ltd R P Pharmaceutical products
US20020197321A1 (en) 1997-10-27 2002-12-26 Harry Seager Solid dispersing vaccine composition for oral delivery
KR20010041918A (ko) 1998-03-16 2001-05-25 알크-아벨로 에이/에스 돌연변이 재조합체 알러젠
GB9901819D0 (en) * 1999-01-27 1999-03-17 Scherer Corp R P Pharmaceutical compositions
FR2790387B1 (fr) 1999-03-01 2001-05-18 Prographarm Laboratoires Comprime orodispersible presentant une faible friabilite et son procede de preparation
FR2791569B1 (fr) * 1999-03-31 2003-05-09 Pf Medicament Composition ou structure microporeuse expansee isotrope a dissolution rapide a usage pharmaceutique, veterinaire, dietetique, alimentaire ou cosmetique et son procede d'obtention
US20060073188A1 (en) * 1999-03-31 2006-04-06 Pierre Fabre Medicament Fast-dissolving isotropic expanded microporous composition or structure for pharmaceutical, veterinary, dietetic, food or cosmetic use and method for obtaining same
GB9908014D0 (en) 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
ES2605109T3 (es) * 1999-08-24 2017-03-13 Abic Biological Laboratories Ltd. Composición de vacuna y procedimiento de uso de la misma
US6264981B1 (en) * 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
DE19951970A1 (de) * 1999-10-28 2001-05-03 Bionetworks Gmbh Arzneimittel für die Toleranzinduktion
GB0020089D0 (en) 2000-08-15 2000-10-04 Smithkline Beecham Biolog Vaccine Composition
DE60136653D1 (de) 2000-11-16 2009-01-02 Alk Abello As Mutante allergene
US6733781B2 (en) * 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
ITMI20010571A1 (it) * 2001-03-19 2002-09-19 Grisotech S A Vaccini assorbibili per via trans-mucosale
PL212139B1 (pl) 2002-05-16 2012-08-31 Alk Abello As Zrekombinowany alergen, zastosowanie zrekombinowanego alergenu, kompozycja zawierająca dwa lub więcej wariantów zrekombinowanych zmutowanych alergenów, zastosowanie takiej kompozycji, kompozycja farmaceutyczna zawierająca zrekombinowany alergen lub wymienioną kompozycję, zastosowanie zrekombinowanego alergenu, kompozycji lub kompozycji farmaceutycznej, sposób przygotowania kompozycji farmaceutycznej, sposób przygotowania zrekombinowanego alergenu, sposób przygotowania biblioteki zrekombinowanego alergenu, sekwencja DNA kodująca zrekombinowany alergen, wektor ekspresyjny obejmujący wymienione DNA, komórka gospodarza zawierająca taki wektor ekspresyjny, sposób produkcji zrekombinowanego mutanta alergenu, oraz oznaczenie diagnostyczne do oceny odpowiedniości, bezpieczeństwa lub wyniku terapii

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10023335B2 (en) 2010-03-29 2018-07-17 Ferring B.V. Fast dissolving pharmaceutical composition
US10086078B2 (en) 2010-03-29 2018-10-02 Ferring B.V. Fast dissolving pharmaceutical composition
US9731018B2 (en) 2011-09-16 2017-08-15 Ferring B.V. Fast dissolving pharmaceutical composition

Also Published As

Publication number Publication date
MXPA05009079A (es) 2006-05-19
KR101136573B1 (ko) 2012-04-23
PL210707B1 (pl) 2012-02-29
WO2004075875A1 (fr) 2004-09-10
HK1089083A1 (en) 2006-11-24
KR20050105491A (ko) 2005-11-04
AU2004216559B2 (en) 2010-05-27
PL378543A1 (pl) 2006-05-02
JP2006519187A (ja) 2006-08-24
WO2004075875A8 (fr) 2004-12-29
AU2004216559A1 (en) 2004-09-10
CA2516291C (fr) 2012-02-14
EP1599185A1 (fr) 2005-11-30
JP4688787B2 (ja) 2011-05-25

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20170224