JP2006519187A5 - - Google Patents
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- Publication number
- JP2006519187A5 JP2006519187A5 JP2006501528A JP2006501528A JP2006519187A5 JP 2006519187 A5 JP2006519187 A5 JP 2006519187A5 JP 2006501528 A JP2006501528 A JP 2006501528A JP 2006501528 A JP2006501528 A JP 2006501528A JP 2006519187 A5 JP2006519187 A5 JP 2006519187A5
- Authority
- JP
- Japan
- Prior art keywords
- dosage form
- allergen
- form according
- solid dosage
- unit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002009 allergen Effects 0.000 claims 31
- 239000002552 dosage form Substances 0.000 claims 31
- 239000007909 solid dosage form Substances 0.000 claims 17
- 239000000126 substance Substances 0.000 claims 11
- 239000003795 chemical substances by application Substances 0.000 claims 9
- 229960004784 ALLERGENS Drugs 0.000 claims 8
- 229960005486 vaccines Drugs 0.000 claims 6
- 239000005913 Maltodextrin Substances 0.000 claims 5
- 229920002774 Maltodextrin Polymers 0.000 claims 5
- 229940035034 maltodextrin Drugs 0.000 claims 5
- 229920002245 Dextrose equivalent Polymers 0.000 claims 4
- 239000003094 microcapsule Substances 0.000 claims 4
- 206010020751 Hypersensitivity Diseases 0.000 claims 3
- 210000002200 Mouth Mucosa Anatomy 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 3
- 230000000172 allergic Effects 0.000 claims 3
- 201000008937 atopic dermatitis Diseases 0.000 claims 3
- 238000004166 bioassay Methods 0.000 claims 3
- 239000008187 granular material Substances 0.000 claims 3
- 239000011159 matrix material Substances 0.000 claims 3
- 238000005259 measurement Methods 0.000 claims 3
- 229920001223 polyethylene glycol Polymers 0.000 claims 3
- 238000002360 preparation method Methods 0.000 claims 3
- 239000007787 solid Substances 0.000 claims 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 2
- FBPFZTCFMRRESA-KAZBKCHUSA-N D-Mannitol Natural products OC[C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KAZBKCHUSA-N 0.000 claims 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N Mannitol Chemical group OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 2
- 239000007891 compressed tablet Substances 0.000 claims 2
- 239000006185 dispersion Substances 0.000 claims 2
- 239000008393 encapsulating agent Substances 0.000 claims 2
- 238000005538 encapsulation Methods 0.000 claims 2
- 238000007710 freezing Methods 0.000 claims 2
- 229940046528 grass pollen Drugs 0.000 claims 2
- 239000000594 mannitol Substances 0.000 claims 2
- 235000010355 mannitol Nutrition 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000000600 sorbitol Substances 0.000 claims 2
- 229940069428 ANTACIDS Drugs 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 210000000214 Mouth Anatomy 0.000 claims 1
- 231100000611 Venom Toxicity 0.000 claims 1
- 210000001048 Venoms Anatomy 0.000 claims 1
- 239000012190 activator Substances 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 230000000240 adjuvant Effects 0.000 claims 1
- 201000005794 allergic hypersensitivity disease Diseases 0.000 claims 1
- 239000003159 antacid agent Substances 0.000 claims 1
- 230000001458 anti-acid Effects 0.000 claims 1
- 230000000111 anti-oxidant Effects 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 238000003556 assay method Methods 0.000 claims 1
- 239000003086 colorant Substances 0.000 claims 1
- 230000003750 conditioning Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 150000002016 disaccharides Chemical class 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 239000000428 dust Substances 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000013355 food flavoring agent Nutrition 0.000 claims 1
- 235000003599 food sweetener Nutrition 0.000 claims 1
- 239000008202 granule composition Substances 0.000 claims 1
- 230000000984 immunochemical Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 150000002772 monosaccharides Chemical group 0.000 claims 1
- 230000003232 mucoadhesive Effects 0.000 claims 1
- -1 mucoadhesives Substances 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 230000002335 preservative Effects 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000008247 solid mixture Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000003765 sweetening agent Substances 0.000 claims 1
- 239000006068 taste-masking agent Substances 0.000 claims 1
- 239000002562 thickening agent Substances 0.000 claims 1
- 229940046536 tree pollen allergenic extracts Drugs 0.000 claims 1
- 150000004043 trisaccharides Chemical class 0.000 claims 1
- 239000002435 venom Substances 0.000 claims 1
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200300318 | 2003-02-28 | ||
DKPA200300318 | 2003-02-28 | ||
US46538303P | 2003-04-25 | 2003-04-25 | |
US60/465,383 | 2003-04-25 | ||
PCT/DK2004/000119 WO2004075875A1 (fr) | 2003-02-28 | 2004-02-24 | Forme de dosage presentant une matrice en saccharide |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2006519187A JP2006519187A (ja) | 2006-08-24 |
JP2006519187A5 true JP2006519187A5 (fr) | 2007-04-12 |
JP4688787B2 JP4688787B2 (ja) | 2011-05-25 |
Family
ID=32929063
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006501528A Expired - Fee Related JP4688787B2 (ja) | 2003-02-28 | 2004-02-24 | 糖類マトリックスを有する剤形 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1599185A1 (fr) |
JP (1) | JP4688787B2 (fr) |
KR (1) | KR101136573B1 (fr) |
AU (1) | AU2004216559B2 (fr) |
CA (1) | CA2516291C (fr) |
HK (1) | HK1089083A1 (fr) |
MX (1) | MXPA05009079A (fr) |
PL (1) | PL210707B1 (fr) |
WO (1) | WO2004075875A1 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060210590A1 (en) | 2005-02-03 | 2006-09-21 | Alk-Abello A/S | Minor allergen control to increase safety of immunotherapy |
KR20080059289A (ko) | 2005-10-04 | 2008-06-26 | 알크-아벨로 에이/에스 | 고체 백신 제형 |
CN107811980B (zh) | 2009-10-30 | 2021-06-18 | Ix 生物医药有限公司 | 快速溶解固体剂型 |
RU2566269C2 (ru) | 2010-03-29 | 2015-10-20 | Ферринг Б.В. | Быстрорастворимая фармацевтическая композиция |
JO3112B1 (ar) | 2010-03-29 | 2017-09-20 | Ferring Bv | تركيبة دوائية سريعة التحلل |
JP5800527B2 (ja) * | 2010-03-30 | 2015-10-28 | 日東電工株式会社 | 安定化医薬組成物、安定化医薬組成物溶液製剤、フィルム状製剤及びフィルム状製剤の製造方法 |
JP5872573B2 (ja) * | 2010-11-04 | 2016-03-01 | ノージン ビーブイ | ポリエチレングリコール含有製剤 |
JP2012240975A (ja) * | 2011-05-20 | 2012-12-10 | Nitto Denko Corp | 医薬組成物及びゼリー状製剤 |
JP2012240978A (ja) * | 2011-05-20 | 2012-12-10 | Nitto Denko Corp | 医薬組成物及びゼリー状製剤 |
KR20140061438A (ko) | 2011-09-16 | 2014-05-21 | 훼링 비.브이. | 속용성 약학 조성물 |
DK3482771T3 (da) * | 2013-03-14 | 2023-03-20 | Nestle Sa | Fremstilling af jordnøddeformuleringer til oral desensibilisering |
US9492535B2 (en) | 2013-03-14 | 2016-11-15 | Aimmune Therapeutics, Inc. | Peanut formulations and uses thereof |
EP2952200A1 (fr) | 2014-06-04 | 2015-12-09 | Alk-Abelló A/S | Allergène pour le traitement prophylactique d'une allergie |
GB2545880A (en) | 2015-10-20 | 2017-07-05 | Glide Pharmaceutical Tech Ltd | Solid formulation |
CN111432804A (zh) * | 2017-11-27 | 2020-07-17 | 帝斯曼知识产权资产管理有限公司 | 冻干的多微粒固体剂型 |
WO2019146777A1 (fr) * | 2018-01-29 | 2019-08-01 | 株式会社リタファーマ | Formulation pharmaceutique et son procédé de production |
CA3137295A1 (fr) | 2019-05-10 | 2020-11-19 | Aimmune Therapeutics, Inc. | Procedes d'amelioration de la qualite de vie d'un patient souffrant d'allergie a l'arachide |
CN116891827B (zh) * | 2023-09-08 | 2024-01-30 | 山东康华生物医疗科技股份有限公司 | 一种nk细胞活性激活体系 |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD107208A1 (fr) | 1973-06-04 | 1974-07-20 | ||
GB1548022A (en) * | 1976-10-06 | 1979-07-04 | Wyeth John & Brother Ltd | Pharmaceutial dosage forms |
IE45770B1 (en) * | 1976-10-06 | 1982-11-17 | Wyeth John & Brother Ltd | Pharmaceutical dosage forms |
FR2609895B1 (fr) | 1987-01-28 | 1991-06-28 | Bruttmann Georges | Nouvelles formes galeniques d'allergenes pour administration par voie per- et sub-linguale |
US5558880A (en) | 1989-12-22 | 1996-09-24 | Janssen Pharmaceutica Inc. | Pharmaceutical and other dosage forms |
US5215756A (en) | 1989-12-22 | 1993-06-01 | Gole Dilip J | Preparation of pharmaceutical and other matrix systems by solid-state dissolution |
US6337082B1 (en) | 1991-10-25 | 2002-01-08 | Biovail Tech Ltd | Saccharide-based matrix |
US5343762A (en) | 1992-10-05 | 1994-09-06 | Rosemount Inc. | Vortex flowmeter |
US5343672A (en) * | 1992-12-01 | 1994-09-06 | Scherer Ltd R P | Method for manufacturing freeze dried dosages in a multilaminate blister pack |
EP0688205A1 (fr) * | 1993-03-11 | 1995-12-27 | Secretech, Inc. | Mucoadhesifs polymeres utilises dans l'administration d'immunogenes par la surface de muqueuses |
US6010719A (en) * | 1997-09-16 | 2000-01-04 | Universiteit Gent | Freeze-dried disintegrating tablets |
GB9722682D0 (en) | 1997-10-27 | 1997-12-24 | Scherer Ltd R P | Pharmaceutical products |
US20020197321A1 (en) | 1997-10-27 | 2002-12-26 | Harry Seager | Solid dispersing vaccine composition for oral delivery |
IL138339A0 (en) | 1998-03-16 | 2001-10-31 | Alk Abello As | Mutant recombinant allergens |
GB9901819D0 (en) * | 1999-01-27 | 1999-03-17 | Scherer Corp R P | Pharmaceutical compositions |
FR2790387B1 (fr) | 1999-03-01 | 2001-05-18 | Prographarm Laboratoires | Comprime orodispersible presentant une faible friabilite et son procede de preparation |
FR2791569B1 (fr) | 1999-03-31 | 2003-05-09 | Pf Medicament | Composition ou structure microporeuse expansee isotrope a dissolution rapide a usage pharmaceutique, veterinaire, dietetique, alimentaire ou cosmetique et son procede d'obtention |
US20060073188A1 (en) * | 1999-03-31 | 2006-04-06 | Pierre Fabre Medicament | Fast-dissolving isotropic expanded microporous composition or structure for pharmaceutical, veterinary, dietetic, food or cosmetic use and method for obtaining same |
GB9908014D0 (en) | 1999-04-08 | 1999-06-02 | Scherer Corp R P | Pharmaceutical compositions |
TR200200477T2 (tr) * | 1999-08-24 | 2002-06-21 | Teva Pharmaceutical Industries Limited | Bir aşı kompozisyonu ve kullanım yöntemi. |
US6264981B1 (en) * | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
DE19951970A1 (de) * | 1999-10-28 | 2001-05-03 | Bionetworks Gmbh | Arzneimittel für die Toleranzinduktion |
GB0020089D0 (en) | 2000-08-15 | 2000-10-04 | Smithkline Beecham Biolog | Vaccine Composition |
NZ525820A (en) | 2000-11-16 | 2005-01-28 | Alk Abello As | Mutant allergens |
US6733781B2 (en) * | 2000-12-06 | 2004-05-11 | Wyeth | Fast dissolving tablet |
ITMI20010571A1 (it) * | 2001-03-19 | 2002-09-19 | Grisotech S A | Vaccini assorbibili per via trans-mucosale |
WO2003096869A2 (fr) | 2002-05-16 | 2003-11-27 | Alk Abelló A/S | Mutants allergenes |
-
2004
- 2004-02-24 MX MXPA05009079A patent/MXPA05009079A/es active IP Right Grant
- 2004-02-24 WO PCT/DK2004/000119 patent/WO2004075875A1/fr active Search and Examination
- 2004-02-24 CA CA2516291A patent/CA2516291C/fr not_active Expired - Fee Related
- 2004-02-24 EP EP04713847A patent/EP1599185A1/fr not_active Withdrawn
- 2004-02-24 AU AU2004216559A patent/AU2004216559B2/en not_active Ceased
- 2004-02-24 KR KR1020057015834A patent/KR101136573B1/ko not_active IP Right Cessation
- 2004-02-24 JP JP2006501528A patent/JP4688787B2/ja not_active Expired - Fee Related
- 2004-02-24 PL PL378543A patent/PL210707B1/pl unknown
-
2006
- 2006-08-25 HK HK06109448.3A patent/HK1089083A1/xx not_active IP Right Cessation
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