CA2516291C - Forme de dosage presentant une matrice en saccharide - Google Patents

Forme de dosage presentant une matrice en saccharide Download PDF

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Publication number
CA2516291C
CA2516291C CA2516291A CA2516291A CA2516291C CA 2516291 C CA2516291 C CA 2516291C CA 2516291 A CA2516291 A CA 2516291A CA 2516291 A CA2516291 A CA 2516291A CA 2516291 C CA2516291 C CA 2516291C
Authority
CA
Canada
Prior art keywords
allergen
dosage form
solid dosage
form according
allergens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2516291A
Other languages
English (en)
Other versions
CA2516291A1 (fr
Inventor
Christian Gauguin Houghton
Annette Roemmelmayer Lundegaard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ALK Abello AS
Original Assignee
ALK Abello AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ALK Abello AS filed Critical ALK Abello AS
Publication of CA2516291A1 publication Critical patent/CA2516291A1/fr
Application granted granted Critical
Publication of CA2516291C publication Critical patent/CA2516291C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2516291A 2003-02-28 2004-02-24 Forme de dosage presentant une matrice en saccharide Expired - Fee Related CA2516291C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200300318 2003-02-28
DKPA200300318 2003-02-28
US46538303P 2003-04-25 2003-04-25
US60/465,383 2003-04-25
PCT/DK2004/000119 WO2004075875A1 (fr) 2003-02-28 2004-02-24 Forme de dosage presentant une matrice en saccharide

Publications (2)

Publication Number Publication Date
CA2516291A1 CA2516291A1 (fr) 2004-09-10
CA2516291C true CA2516291C (fr) 2012-02-14

Family

ID=32929063

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2516291A Expired - Fee Related CA2516291C (fr) 2003-02-28 2004-02-24 Forme de dosage presentant une matrice en saccharide

Country Status (9)

Country Link
EP (1) EP1599185A1 (fr)
JP (1) JP4688787B2 (fr)
KR (1) KR101136573B1 (fr)
AU (1) AU2004216559B2 (fr)
CA (1) CA2516291C (fr)
HK (1) HK1089083A1 (fr)
MX (1) MXPA05009079A (fr)
PL (1) PL210707B1 (fr)
WO (1) WO2004075875A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060210590A1 (en) 2005-02-03 2006-09-21 Alk-Abello A/S Minor allergen control to increase safety of immunotherapy
US20090155351A1 (en) 2005-10-04 2009-06-18 Alk-Abello A/S Solid Vaccine Formulation
TR201902233T4 (tr) 2009-10-30 2019-03-21 Ix Biopharma Ltd Hızlı çözünen katı dozaj formu.
JO3112B1 (ar) 2010-03-29 2017-09-20 Ferring Bv تركيبة دوائية سريعة التحلل
AU2011234637B2 (en) 2010-03-29 2013-08-29 Ferring B.V. A fast dissolving pharmaceutical composition
JP5800527B2 (ja) * 2010-03-30 2015-10-28 日東電工株式会社 安定化医薬組成物、安定化医薬組成物溶液製剤、フィルム状製剤及びフィルム状製剤の製造方法
AU2011324995B2 (en) * 2010-11-04 2015-12-24 Norgine Bv Formulations comprising polyethylene glycol
JP2012240975A (ja) * 2011-05-20 2012-12-10 Nitto Denko Corp 医薬組成物及びゼリー状製剤
JP2012240978A (ja) * 2011-05-20 2012-12-10 Nitto Denko Corp 医薬組成物及びゼリー状製剤
EP2755632A1 (fr) 2011-09-16 2014-07-23 Ferring BV Composition pharmaceutique à dissolution rapide
DK3482771T3 (da) * 2013-03-14 2023-03-20 Nestle Sa Fremstilling af jordnøddeformuleringer til oral desensibilisering
WO2014159609A1 (fr) 2013-03-14 2014-10-02 Allergen Research Corporation Préparations à base d'arachide et leurs utilisations
EP2952200A1 (fr) 2014-06-04 2015-12-09 Alk-Abelló A/S Allergène pour le traitement prophylactique d'une allergie
GB2545880A (en) 2015-10-20 2017-07-05 Glide Pharmaceutical Tech Ltd Solid formulation
CN111432804A (zh) * 2017-11-27 2020-07-17 帝斯曼知识产权资产管理有限公司 冻干的多微粒固体剂型
JP6592791B1 (ja) * 2018-01-29 2019-10-23 株式会社リタファーマ 医薬製剤及びその製造方法
US11229673B2 (en) 2019-05-10 2022-01-25 Société des Produits Nestlé S.A. Methods for improving the quality of life of a patient with a peanut allergy
CN116891827B (zh) * 2023-09-08 2024-01-30 山东康华生物医疗科技股份有限公司 一种nk细胞活性激活体系

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD107208A1 (fr) 1973-06-04 1974-07-20
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
IE45770B1 (en) * 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
FR2609895B1 (fr) 1987-01-28 1991-06-28 Bruttmann Georges Nouvelles formes galeniques d'allergenes pour administration par voie per- et sub-linguale
US5558880A (en) 1989-12-22 1996-09-24 Janssen Pharmaceutica Inc. Pharmaceutical and other dosage forms
US5215756A (en) 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
US6337082B1 (en) 1991-10-25 2002-01-08 Biovail Tech Ltd Saccharide-based matrix
US5343762A (en) 1992-10-05 1994-09-06 Rosemount Inc. Vortex flowmeter
US5343672A (en) * 1992-12-01 1994-09-06 Scherer Ltd R P Method for manufacturing freeze dried dosages in a multilaminate blister pack
BR9405996A (pt) * 1993-03-11 1995-12-19 Secretech Inc Mucoadesivos poliméricos na distribuição de imunógenos em superfícies mucosais
US6010719A (en) * 1997-09-16 2000-01-04 Universiteit Gent Freeze-dried disintegrating tablets
US20020197321A1 (en) 1997-10-27 2002-12-26 Harry Seager Solid dispersing vaccine composition for oral delivery
GB9722682D0 (en) * 1997-10-27 1997-12-24 Scherer Ltd R P Pharmaceutical products
AU749749B2 (en) 1998-03-16 2002-07-04 Alk-Abello A/S Mutant recombinant allergens
GB9901819D0 (en) 1999-01-27 1999-03-17 Scherer Corp R P Pharmaceutical compositions
FR2790387B1 (fr) 1999-03-01 2001-05-18 Prographarm Laboratoires Comprime orodispersible presentant une faible friabilite et son procede de preparation
FR2791569B1 (fr) * 1999-03-31 2003-05-09 Pf Medicament Composition ou structure microporeuse expansee isotrope a dissolution rapide a usage pharmaceutique, veterinaire, dietetique, alimentaire ou cosmetique et son procede d'obtention
US20060073188A1 (en) * 1999-03-31 2006-04-06 Pierre Fabre Medicament Fast-dissolving isotropic expanded microporous composition or structure for pharmaceutical, veterinary, dietetic, food or cosmetic use and method for obtaining same
GB9908014D0 (en) 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
US6541001B1 (en) * 1999-08-24 2003-04-01 Teva Pharmaceutical Industries, Ltd. Vaccine composition and method of using the same
US6264981B1 (en) * 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
DE19951970A1 (de) * 1999-10-28 2001-05-03 Bionetworks Gmbh Arzneimittel für die Toleranzinduktion
GB0020089D0 (en) 2000-08-15 2000-10-04 Smithkline Beecham Biolog Vaccine Composition
JP2004521618A (ja) 2000-11-16 2004-07-22 アルカベロ アクチェセルスカプ 新規変異体アレルゲン
US6733781B2 (en) * 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
ITMI20010571A1 (it) * 2001-03-19 2002-09-19 Grisotech S A Vaccini assorbibili per via trans-mucosale
AU2003223934A1 (en) 2002-05-16 2003-12-02 Alk Abello A/S Recombinant bet. v. 1. allergen mutants, methods and process thereof

Also Published As

Publication number Publication date
JP4688787B2 (ja) 2011-05-25
EP1599185A1 (fr) 2005-11-30
MXPA05009079A (es) 2006-05-19
PL210707B1 (pl) 2012-02-29
JP2006519187A (ja) 2006-08-24
AU2004216559B2 (en) 2010-05-27
PL378543A1 (pl) 2006-05-02
CA2516291A1 (fr) 2004-09-10
KR101136573B1 (ko) 2012-04-23
KR20050105491A (ko) 2005-11-04
WO2004075875A1 (fr) 2004-09-10
WO2004075875A8 (fr) 2004-12-29
AU2004216559A1 (en) 2004-09-10
HK1089083A1 (en) 2006-11-24

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EEER Examination request
MKLA Lapsed

Effective date: 20170224