CA2332331A1 - Traitement de tumeurs humaines a l'aide d'un rayonnement et d'inhibiteurs de tyrosine kinases de recepteurs du facteur de croissance - Google Patents

Traitement de tumeurs humaines a l'aide d'un rayonnement et d'inhibiteurs de tyrosine kinases de recepteurs du facteur de croissance Download PDF

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Publication number
CA2332331A1
CA2332331A1 CA002332331A CA2332331A CA2332331A1 CA 2332331 A1 CA2332331 A1 CA 2332331A1 CA 002332331 A CA002332331 A CA 002332331A CA 2332331 A CA2332331 A CA 2332331A CA 2332331 A1 CA2332331 A1 CA 2332331A1
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CA
Canada
Prior art keywords
egfr
family
radiation
antibodies
receptor tyrosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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CA002332331A
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English (en)
Inventor
Francisco Robert
Mansoor N. Saleh
Donald Jay Buchsbaum
Harlan W. Waksal
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UAB Research Foundation
ImClone LLC
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Individual
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Publication of CA2332331A1 publication Critical patent/CA2332331A1/fr
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne un procédé servant à inhiber la croissance de tumeurs chez des patients humains, qui comporte l'étape consistant à traiter les patients humains à l'aide d'une quantité efficace de rayonnement combiné à un inhibiteur de tyrosine kinase de récepteurs protéinique non radiomarqué, la surexpression de celle-ci pouvant entraîner la formation de tumeurs.
CA002332331A 1998-05-15 1999-05-14 Traitement de tumeurs humaines a l'aide d'un rayonnement et d'inhibiteurs de tyrosine kinases de recepteurs du facteur de croissance Abandoned CA2332331A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US8561398P 1998-05-15 1998-05-15
US7961298A 1998-05-15 1998-05-15
US60/085,613 1998-05-15
US09/079,612 1998-05-15
US20613898A 1998-12-07 1998-12-07
US09/206,138 1998-12-07
PCT/US1999/010741 WO1999060023A1 (fr) 1998-05-15 1999-05-14 Traitement de tumeurs humaines a l'aide d'un rayonnement et d'inhibiteurs de tyrosine kinases de recepteurs du facteur de croissance

Publications (1)

Publication Number Publication Date
CA2332331A1 true CA2332331A1 (fr) 1999-11-25

Family

ID=27373511

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002332331A Abandoned CA2332331A1 (fr) 1998-05-15 1999-05-14 Traitement de tumeurs humaines a l'aide d'un rayonnement et d'inhibiteurs de tyrosine kinases de recepteurs du facteur de croissance

Country Status (14)

Country Link
EP (1) EP1080113A4 (fr)
JP (1) JP2002515511A (fr)
KR (1) KR20010071271A (fr)
CN (1) CN1314917A (fr)
AU (1) AU4079999A (fr)
BR (1) BR9910511A (fr)
CA (1) CA2332331A1 (fr)
CZ (1) CZ20004224A3 (fr)
HK (1) HK1040720A1 (fr)
IL (1) IL139707A0 (fr)
MX (1) MXPA00011248A (fr)
PL (1) PL348634A1 (fr)
SK (1) SK17282000A3 (fr)
WO (1) WO1999060023A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9085622B2 (en) 2010-09-03 2015-07-21 Glaxosmithkline Intellectual Property Development Limited Antigen binding proteins

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Publication number Priority date Publication date Assignee Title
US9085622B2 (en) 2010-09-03 2015-07-21 Glaxosmithkline Intellectual Property Development Limited Antigen binding proteins

Also Published As

Publication number Publication date
AU4079999A (en) 1999-12-06
CZ20004224A3 (cs) 2002-02-13
MXPA00011248A (es) 2004-09-06
IL139707A0 (en) 2002-02-10
WO1999060023A1 (fr) 1999-11-25
CN1314917A (zh) 2001-09-26
PL348634A1 (en) 2002-06-03
HK1040720A1 (zh) 2002-06-21
SK17282000A3 (sk) 2002-04-04
KR20010071271A (ko) 2001-07-28
EP1080113A4 (fr) 2002-04-17
BR9910511A (pt) 2001-11-20
JP2002515511A (ja) 2002-05-28
EP1080113A1 (fr) 2001-03-07

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