CA2281473C - Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same - Google Patents

Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same Download PDF

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Publication number
CA2281473C
CA2281473C CA002281473A CA2281473A CA2281473C CA 2281473 C CA2281473 C CA 2281473C CA 002281473 A CA002281473 A CA 002281473A CA 2281473 A CA2281473 A CA 2281473A CA 2281473 C CA2281473 C CA 2281473C
Authority
CA
Canada
Prior art keywords
dosage form
binder
active ingredients
moisture
bulk material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002281473A
Other languages
English (en)
French (fr)
Other versions
CA2281473A1 (en
Inventor
Jaedeok Yoo
Sandeep Kumar
Donald C. Monkhouse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Therics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therics Inc filed Critical Therics Inc
Publication of CA2281473A1 publication Critical patent/CA2281473A1/en
Application granted granted Critical
Publication of CA2281473C publication Critical patent/CA2281473C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002281473A 1997-02-20 1998-02-20 Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same Expired - Lifetime CA2281473C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3888397P 1997-02-20 1997-02-20
US3828497P 1997-02-20 1997-02-20
US60/038,284 1997-02-20
US60/038,883 1997-02-20
PCT/US1998/003256 WO1998036738A1 (en) 1997-02-20 1998-02-20 Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same

Publications (2)

Publication Number Publication Date
CA2281473A1 CA2281473A1 (en) 1998-08-27
CA2281473C true CA2281473C (en) 2007-01-16

Family

ID=26715043

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002281473A Expired - Lifetime CA2281473C (en) 1997-02-20 1998-02-20 Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same

Country Status (9)

Country Link
US (3) US6471992B1 (enExample)
EP (1) EP0973507B1 (enExample)
JP (3) JP4563516B2 (enExample)
AT (1) ATE421318T1 (enExample)
AU (1) AU736912B2 (enExample)
CA (1) CA2281473C (enExample)
DE (1) DE69840495D1 (enExample)
ES (1) ES2318869T3 (enExample)
WO (1) WO1998036738A1 (enExample)

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* Cited by examiner, † Cited by third party
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Also Published As

Publication number Publication date
US20120207929A1 (en) 2012-08-16
JP4563516B2 (ja) 2010-10-13
US9463160B2 (en) 2016-10-11
EP0973507A4 (en) 2006-08-23
JP2010120938A (ja) 2010-06-03
EP0973507B1 (en) 2009-01-21
US9114072B2 (en) 2015-08-25
JP2009215305A (ja) 2009-09-24
JP2001512488A (ja) 2001-08-21
WO1998036738A1 (en) 1998-08-27
AU6331498A (en) 1998-09-09
US6471992B1 (en) 2002-10-29
US20030133975A1 (en) 2003-07-17
ATE421318T1 (de) 2009-02-15
EP0973507A1 (en) 2000-01-26
DE69840495D1 (de) 2009-03-12
CA2281473A1 (en) 1998-08-27
ES2318869T3 (es) 2009-05-01
AU736912B2 (en) 2001-08-02
JP5091910B2 (ja) 2012-12-05

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