ATE208615T1 - Verfahren zur herstellung von gefriergetrockneten arzneistoffdosierungsformen - Google Patents

Verfahren zur herstellung von gefriergetrockneten arzneistoffdosierungsformen

Info

Publication number
ATE208615T1
ATE208615T1 AT94923921T AT94923921T ATE208615T1 AT E208615 T1 ATE208615 T1 AT E208615T1 AT 94923921 T AT94923921 T AT 94923921T AT 94923921 T AT94923921 T AT 94923921T AT E208615 T1 ATE208615 T1 AT E208615T1
Authority
AT
Austria
Prior art keywords
pct
therapeutic agent
dosage forms
sec
tablet
Prior art date
Application number
AT94923921T
Other languages
English (en)
Inventor
Sang K Wong
Patrick Kearney
Original Assignee
Scherer Corp R P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherer Corp R P filed Critical Scherer Corp R P
Application granted granted Critical
Publication of ATE208615T1 publication Critical patent/ATE208615T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
AT94923921T 1993-07-09 1994-07-08 Verfahren zur herstellung von gefriergetrockneten arzneistoffdosierungsformen ATE208615T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8903493A 1993-07-09 1993-07-09
PCT/US1994/007618 WO1995001782A2 (en) 1993-07-09 1994-07-08 Method for making freeze dried drug dosage forms

Publications (1)

Publication Number Publication Date
ATE208615T1 true ATE208615T1 (de) 2001-11-15

Family

ID=22215166

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94923921T ATE208615T1 (de) 1993-07-09 1994-07-08 Verfahren zur herstellung von gefriergetrockneten arzneistoffdosierungsformen

Country Status (9)

Country Link
US (1) US5631023A (de)
EP (1) EP0804170B1 (de)
JP (1) JP3233638B2 (de)
AT (1) ATE208615T1 (de)
AU (1) AU691195B2 (de)
CA (1) CA2166891C (de)
DE (1) DE69429119T2 (de)
ES (1) ES2162867T3 (de)
WO (1) WO1995001782A2 (de)

Families Citing this family (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5457895A (en) * 1993-10-01 1995-10-17 R. P. Scherer Corporation Method of identifying freeze-dried dosage forms
US5837287A (en) * 1994-10-28 1998-11-17 R P Scherer Corporation Process for preparing solid pharmaceutical dosage forms
US6465016B2 (en) * 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
JP4563516B2 (ja) 1997-02-20 2010-10-13 マサチューセッツ インスティテュート オブ テクノロジー 迅速分散性を示す投与剤形、その使用法並びにその製造方法
US20040023948A1 (en) * 1997-03-24 2004-02-05 Green Richard David Fast-dispersing dosage form containing 5-HT1 agonists
US5976577A (en) * 1997-07-11 1999-11-02 Rp Scherer Corporation Process for preparing fast dispersing solid oral dosage form
ATE323467T1 (de) * 1997-07-25 2006-05-15 Alpex Pharma Sa Verfahren zur herstellung eines granulates, geeignet zur herstellung schnell-freisetzender, im mund löslicher tabletten
TW527195B (en) 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
EP1079808B1 (de) 1998-05-29 2004-02-11 Skyepharma Canada Inc. Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben
SE9803240D0 (sv) 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
US8236352B2 (en) * 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
US20040013613A1 (en) * 2001-05-18 2004-01-22 Jain Rajeev A Rapidly disintegrating solid oral dosage form
HUP0105089A3 (en) * 1998-11-20 2002-09-30 Skyepharma Canada Inc Compositions containing the active ingredient in form dispersible phospholipid stabilized microparticles
US6552024B1 (en) 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
GB9901819D0 (en) * 1999-01-27 1999-03-17 Scherer Corp R P Pharmaceutical compositions
GB9908014D0 (en) * 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
US20040115134A1 (en) * 1999-06-22 2004-06-17 Elan Pharma International Ltd. Novel nifedipine compositions
US6284270B1 (en) 1999-08-04 2001-09-04 Drugtech Corporation Means for creating a mass having structural integrity
WO2001021154A2 (en) * 1999-09-21 2001-03-29 Rtp Pharma Inc. Surface modified particulate compositions of biologically active substances
BR0007360A (pt) * 1999-12-23 2001-08-14 Johnson & Johnson Composição de liberação controlada
US6316029B1 (en) 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
EP1301177A2 (de) * 2000-07-10 2003-04-16 Therics, Inc. Verfahren und materialien zur steuerung der wanderung einer binderflüssigkeit in ein pulver
IN192750B (de) * 2000-12-15 2004-05-15 Ranbaxy Lab Ltd
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
US6814978B2 (en) * 2000-12-29 2004-11-09 Mcneil-Ppc, Inc. Process for preparing a soft tablet
EP1413331B1 (de) * 2001-01-26 2007-10-03 Schering Corporation Kombinationen vom PPAR-Aktivator Fenofibrat mit dem Hemmer der Sterol-Absorption Ezetimibe zur Behandlung von kardiovaskulären Indikationen
US6509040B1 (en) 2001-06-22 2003-01-21 R.P. Scherer Corporation Fast dispersing dosage forms essentially free of mammalian gelatin
EP1423116A1 (de) * 2001-08-14 2004-06-02 Biotie Therapies Corp. Verfahren zur behandlung von alkoholismus oder alkoholmissbrauch
ES2292848T3 (es) 2001-10-12 2008-03-16 Elan Pharma International Limited Composiciones que tienen una combinacion de caracteristicas de liberacion inmediata y liberacion controlada.
EP1485296B1 (de) * 2002-02-13 2011-07-20 Michael K. Weibel Arzneimitteldosenform und -herstellungsverfahren
EP1487419A2 (de) * 2002-03-20 2004-12-22 Elan Pharma International Limited Schnell auflösende dosierformen mit verringerter sprödigkeit
US20030215498A1 (en) * 2002-05-17 2003-11-20 Harland Ronald S. Rapidly disintegrating comressed tablets comprising biologically active compounds
US20040029843A1 (en) * 2002-06-20 2004-02-12 Orapharma, Inc. Rapidly disintegrating formulations for treating or preventing mucositis
US20040156895A1 (en) * 2002-11-12 2004-08-12 Elan Pharma International Ltd. Solid dosage forms comprising pullulan
AU2003298319A1 (en) 2002-12-03 2004-06-23 Celltran Limited Pharmaceutical compositions of cell lysate and processes for the production and use thereof
EP1601668B1 (de) * 2003-03-07 2008-08-27 Schering Corporation Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
ATE418551T1 (de) * 2003-03-07 2009-01-15 Schering Corp Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
US20040234579A1 (en) * 2003-05-22 2004-11-25 Mark D. Finke, Inc. Dietary supplements and methods of preparing and administering dietary supplements
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
EP2322195A2 (de) 2003-11-10 2011-05-18 Reprise Biopharmaceutics, LLC Pharmazeutische Zusammensetzungen mit niedrigen Dosen von Desmopressin
DE20321887U1 (de) 2003-11-10 2012-01-20 Allergan, Inc. Arzneimittel umfassend niedrige Dosierungen von Desmopressin
MX2007003032A (es) 2004-09-21 2007-05-21 Hypnion Inc Analogos de loxapina y metodos de uso de los mismos.
WO2007019345A1 (en) 2005-08-04 2007-02-15 Sirtris Pharmaceuticals, Inc. Imidazopyridine derivatives as sirtuin modulating agents
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
US8048449B2 (en) * 2005-12-27 2011-11-01 Jubilant Organosys Ltd. Mouth dissolving pharmaceutical composition and process for preparing the same
US20070243248A1 (en) * 2006-04-14 2007-10-18 Cherukuri S Rao Rapidly disintegrating solid oral dosage form of liquid dispersions
WO2007130373A2 (en) * 2006-05-01 2007-11-15 Capricorn Pharma, Inc. Novel triptan formulations and methods for making them
WO2007143676A2 (en) * 2006-06-05 2007-12-13 Verus Pharmaceuticals, Inc. Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
WO2007143674A2 (en) * 2006-06-05 2007-12-13 Verus Pharmaceuticals, Inc. Methods for buccal, lingual or sublingual dosing regimens of epinephrine for the treatment of allergic emergencies
AR061485A1 (es) * 2006-06-15 2008-08-27 Serenex Inc Composiciones estabilizadas de tetraciclina
ES2500165T3 (es) 2006-06-29 2014-09-30 Kinex Pharmaceuticals, Llc Composiciones de biarilo y métodos para modular una cascada de quinasas
WO2008140772A2 (en) * 2007-05-08 2008-11-20 Hercules Incorporated Robust rapid disintegration tablet formulation
WO2009002084A2 (en) * 2007-06-27 2008-12-31 Hanmi Pharm. Co., Ltd. Method for preparing rapidly disintegrating formulation for oral administration and apparatus for preparing and packing the same
US20090060983A1 (en) * 2007-08-30 2009-03-05 Bunick Frank J Method And Composition For Making An Orally Disintegrating Dosage Form
CN101932319A (zh) 2007-10-20 2010-12-29 金克斯医药品有限公司 用于调控激酶级联的药物组合物以其使用方法
EP2217213B1 (de) * 2007-10-31 2017-05-24 Johnson & Johnson Consumer Inc. Im mund zerfallende dosierform
US20090226522A1 (en) * 2008-02-28 2009-09-10 Howes Simon A M Process to minimize polymorphism
US9072688B2 (en) * 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9060926B2 (en) * 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8793075B2 (en) 2008-10-31 2014-07-29 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US20100111834A1 (en) * 2008-10-31 2010-05-06 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Compositions and methods for therapeutic delivery with frozen particles
US8858912B2 (en) * 2008-10-31 2014-10-14 The Invention Science Fund I, Llc Frozen compositions and methods for piercing a substrate
US8762067B2 (en) * 2008-10-31 2014-06-24 The Invention Science Fund I, Llc Methods and systems for ablation or abrasion with frozen particles and comparing tissue surface ablation or abrasion data to clinical outcome data
US20100111857A1 (en) 2008-10-31 2010-05-06 Boyden Edward S Compositions and methods for surface abrasion with frozen particles
US8725420B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8545857B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US8603494B2 (en) * 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US8414356B2 (en) * 2008-10-31 2013-04-09 The Invention Science Fund I, Llc Systems, devices, and methods for making or administering frozen particles
US8545856B2 (en) * 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US9072799B2 (en) 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8545855B2 (en) * 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8721583B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US9050070B2 (en) * 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8788211B2 (en) * 2008-10-31 2014-07-22 The Invention Science Fund I, Llc Method and system for comparing tissue ablation or abrasion data to data related to administration of a frozen particle composition
US8731841B2 (en) * 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8603495B2 (en) * 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US9060931B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US20100111845A1 (en) * 2008-10-31 2010-05-06 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Compositions and methods for therapeutic delivery with frozen particles
US8731840B2 (en) * 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9050317B2 (en) * 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8409376B2 (en) 2008-10-31 2013-04-02 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8551505B2 (en) * 2008-10-31 2013-10-08 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9060934B2 (en) * 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8731842B2 (en) * 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
KR101075556B1 (ko) * 2008-11-21 2011-10-20 씨제이제일제당 (주) 구강내 속붕해정 및 그 제조방법
US8545879B2 (en) 2009-08-31 2013-10-01 Wilmington Pharmaceuticals, Llc Fast disintegrating compositions of meloxicam
US8807979B2 (en) 2009-09-24 2014-08-19 Mcneil-Ppc, Inc. Machine for the manufacture of dosage forms utilizing radiofrequency energy
US20110070286A1 (en) * 2009-09-24 2011-03-24 Andreas Hugerth Process for the manufacture of nicotine-comprising chewing gum and nicotine-comprising chewing gum manufactured according to said process
US8313768B2 (en) 2009-09-24 2012-11-20 Mcneil-Ppc, Inc. Manufacture of tablet having immediate release region and sustained release region
US8858210B2 (en) 2009-09-24 2014-10-14 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
TR201002084A1 (tr) 2010-03-19 2011-10-21 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Oral yolla dağılan donepezil tablet formülasyonları ve hazırlama yöntemi
EP2377522B1 (de) 2010-04-15 2013-01-16 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Formulierungen von im Mund zerfallenden Mirtazapintabletten und Herstellungsverfahren dafür.
EP2611781A1 (de) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Schnelllösliche darreichungsformen von 5-ht2c-agonisten
WO2012056319A1 (en) 2010-10-27 2012-05-03 Dynamix Pharmaceuticals Ltd. Sulfonamides for the modulation of pkm2
US8987271B2 (en) 2010-12-22 2015-03-24 Eutropics Pharmaceuticals, Inc. 2,2′-biphenazine compounds and methods useful for treating disease
EP2684167B1 (de) 2011-03-08 2020-09-09 Eutropics Pharmaceuticals, Inc. Zusammensetzungen und verfahren zur behandlung von erkrankungen
WO2012160447A1 (en) 2011-05-25 2012-11-29 Dynamix Pharmaceuticals Ltd. 3, 5 -diphenyl- substituted pyrazolines for the treatment of cancer, proliferative, inflammatory or autoimmune diseases
US8937065B2 (en) 2011-06-07 2015-01-20 Clevexel Pharma Compositions and methods for modulating a kinase
EP2609911A1 (de) 2011-12-29 2013-07-03 Sanovel Ilac Sanayi ve Ticaret A.S. Neuartiges Verfahren zur Herstellung von oral zerfallenden Flurbiprofen-Formulierungen
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
WO2013192423A2 (en) 2012-06-20 2013-12-27 Eutropics Pharmaceuticals, Inc. Methods and compositions useful for treating diseases involving bcl-2 family proteins with quinoline derivatives
CN105263907B (zh) 2012-08-30 2018-11-20 阿西纳斯公司 作为蛋白质酪氨酸激酶调节剂的n-(3-氟苄基)-2-(5-(4-吗啉代苯基)吡啶-2-基)乙酰胺
AU2014228861B2 (en) 2013-03-15 2018-05-24 Aprecia Pharmaceuticals LLC Rapidly dispersible dosage form of topiramate
CA2906107C (en) 2013-03-15 2021-08-24 Aprecia Pharmaceuticals Company Rapidly dispersible dosage form of oxcarbazepine
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
CA2906029C (en) 2013-03-15 2017-09-05 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
JP6505721B2 (ja) 2014-01-10 2019-04-24 ジョンソン・アンド・ジョンソン・コンシューマー・インコーポレイテッド 高周波及び損失性被覆粒子を使用した錠剤の製造プロセス
CA2961445C (en) 2014-09-17 2019-03-26 Babu Padmanabhan Effervescent composition and method of making it
MX368838B (es) 2014-11-21 2019-10-18 Biohaven Pharm Holding Co Ltd Administracion sublingual de riluzol.
US11219594B2 (en) 2015-12-12 2022-01-11 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
CN105663065A (zh) * 2016-04-01 2016-06-15 曾岚 一种含疏水性活性物质的冻干舌下片剂及其制备方法
RS62935B1 (sr) 2016-05-20 2022-03-31 Biohaven Therapeutics Ltd Primena riluzola, prolekova riluzola ili analoga riluzola sa imunoterapijama za lečenje kancera
TWI755418B (zh) 2016-08-12 2022-02-21 美商亞瑟尼克斯公司 聯芳組成物和調控激酶級聯之方法
CA3045043A1 (en) 2016-12-31 2018-07-05 Bioxcel Therapeutics, Inc. Use of sublingual dexmedetomidine for the treatment of agitation
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
US10238600B2 (en) 2017-04-13 2019-03-26 Richard C. Fuisz Package, system and methods for custody and control of drugs, and method and composition for making an oral soluble film, containing at least one active agent
US9901545B1 (en) 2017-04-13 2018-02-27 Richard C. Fuisz Method and composition for making an oral soluble film, containing at least one active agent
CZ307916B6 (cs) 2017-05-08 2019-08-21 mcePharma s. r. o. Orodispergovatelná tableta s biodostupným kurkuminem a její použití
JP6572257B2 (ja) * 2017-05-16 2019-09-04 大塚製薬株式会社 アリピプラゾールの経口速溶性組成物
EP3706739A4 (de) 2017-11-12 2021-08-04 Biohaven Pharmaceutical Holding Company Ltd. Verwendung von riluzolprodrugs zur behandlung von ataxien
CN115154440A (zh) 2018-06-27 2022-10-11 比奥克斯塞尔医疗股份有限公司 含右美托咪定的膜制剂及其制造方法
US20220016074A1 (en) 2018-11-21 2022-01-20 Rosemont Pharmaceuticals Limited Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability
BR112022000992A2 (pt) 2019-07-19 2022-06-14 Arx Llc Regimes de tratamento de dexmedetomidina não sedantes
CA3183295A1 (en) 2020-06-26 2021-12-30 Jaedeok Yoo Rapidly-orodispersible tablets having an interior cavity
US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
CA1097233A (en) * 1977-07-20 1981-03-10 George K. E. Gregory Packages
GB2111423B (en) * 1981-12-02 1985-06-26 Wyeth John & Brother Ltd Making quick-dissolving pills
IE53696B1 (en) * 1981-12-02 1989-01-18 Wyeth John & Brother Ltd Solid shaped articles
EP0084705B1 (de) * 1981-12-11 1987-01-14 JOHN WYETH & BROTHER LIMITED Verfahren zur Herstellung von festen Formgegenständen
ES8703865A2 (es) * 1985-06-28 1987-03-16 Barisintex Sa Perfeccionamientos en la patente de invencion n.544661 por: procedimiento de preparazcion de ascorbatos antagonistas h2-receptores.
US4758589A (en) * 1985-12-23 1988-07-19 Smithkline Beckman Corporation Tetraphosphine-coordinated gold(I) complexes
HU196775B (en) * 1986-08-05 1989-01-30 Richter Gedeon Vegyeszet Process for production of morfologically unique new modifications of famotidin and medical compositions containing such substances
JPS6368516A (ja) * 1986-09-10 1988-03-28 Lion Corp 口腔組成物
GB8706176D0 (en) * 1987-03-16 1987-04-23 Wellcome Found Therapeutic nucleosides
NO882037L (no) * 1987-06-22 1988-12-23 Marga Para La Investigacion Sa Famotidin, polymerte former og fremstilling derav.
US5275823A (en) * 1989-04-27 1994-01-04 Smith Kline & French Laboratories Ltd. Pharmaceutical compositions
US4946684A (en) * 1989-06-20 1990-08-07 American Home Products Corporation Fast dissolving dosage forms
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
US5188825A (en) * 1989-12-28 1993-02-23 Iles Martin C Freeze-dried dosage forms and methods for preparing the same
US5075114A (en) * 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
JP2640292B2 (ja) * 1990-11-22 1997-08-13 富士写真フイルム株式会社 静電記録フイルム
JPH0515319A (ja) * 1990-12-14 1993-01-26 Sunstar Inc 水難溶性塩類の分散法およびそれを分散してなる飲用組成物
US5178867A (en) * 1991-08-19 1993-01-12 Alza Corporation Dosage form for delivering drug in short-time period
US5622717A (en) * 1991-12-17 1997-04-22 Fuisz Technologies Ltd. Ulcer prevention method using a melt-spun hydrogel

Also Published As

Publication number Publication date
CA2166891C (en) 2001-07-03
CA2166891A1 (en) 1995-01-19
WO1995001782A3 (en) 1995-03-09
ES2162867T3 (es) 2002-01-16
AU691195B2 (en) 1998-05-14
EP0804170B1 (de) 2001-11-14
DE69429119T2 (de) 2002-07-18
DE69429119D1 (de) 2001-12-20
WO1995001782A2 (en) 1995-01-19
US5631023A (en) 1997-05-20
JP3233638B2 (ja) 2001-11-26
AU7397394A (en) 1995-02-06
JPH09502622A (ja) 1997-03-18
EP0804170A2 (de) 1997-11-05

Similar Documents

Publication Publication Date Title
ATE208615T1 (de) Verfahren zur herstellung von gefriergetrockneten arzneistoffdosierungsformen
ATE213164T1 (de) Verwendung von nona- und dekapeptiden zur herstellung eines arzneimittels zur bekämpfung von aids
IL111077A (en) Pyridine derivatives processes for the preparation thereof and pharmaceutical compositions containing them
AU7880991A (en) A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols
AU1537095A (en) Therapeutic agents containing thyroid hormones
PL325825A1 (en) Microemulsion for use as a carrier for administering active compounds
EP1077070A3 (de) Orale Darreichungsform
DE3687501D1 (de) Verwendung von gamma-linolensaeure und verwandten verbindungen zur herstellung eines arneimittels zur behandlung von komplikationen bei diabetes mellitus.
DE3684409D1 (de) Verwendung von gamma-linolensaeure und verwandten verbindungen zur herstellung eubnes arzneimittels zur behandlung von endometriose.
EP0221041A3 (de) Benzimidazolderivate, Verfahren zu deren Herstellung und ihre pharmazeutische Verwendung
HU912064D0 (en) Process for the production of aralyphic n-substituted amino-alcane-phosphine acids and medical preparations containing them
ZA948669B (en) New pyrazine carboxamide derivatives the preparation thereof and their use in pharmaceutical compositions
HUP0104702A2 (hu) Klosztridium toxinszármazékok alkalmazása horkolási zajok elnyomására szolgáló gyógyászati készítmények előállítására
JPS6470415A (en) Skin permeable remedy system
HUT52040A (en) Process for producing diaryl-derivatives and pharmaceutical compositions containing them
PL321567A1 (en) Oral administration forms containing a beta-lactame antibiotic
ATE221772T1 (de) Verfahren und apparat zur herstellung von schnelllöslichen dosierungseinheiten und daraus erhältliches produkt
GR3007981T3 (de)
CA2163197A1 (en) Tri(platinum) complexes
KR960700701A (ko) 파라세타몰 및 l-시스테인 또는 이것의 전구물질을 함유하는 약제조성물(pharmaceutical compositions comprising paracetamol and l-cysteine or a precursor thereof)
JPH08157362A (ja) 油性物質含有固形製剤の製法
DE69102143D1 (de) Spiramycin enthaltende arzneimittel und verfahren zu deren herstellung.
JP2616822B2 (ja) カルシウム製剤
GB8804188D0 (en) Pharmaceutical compositions
JPH0769877A (ja) 分枝鎖アミノ酸を有効成分とする経口投与薬

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties