ES2162867T3 - Metodo de fabricacion de formas de dosificacion de farmacos liofilizados. - Google Patents

Metodo de fabricacion de formas de dosificacion de farmacos liofilizados.

Info

Publication number
ES2162867T3
ES2162867T3 ES94923921T ES94923921T ES2162867T3 ES 2162867 T3 ES2162867 T3 ES 2162867T3 ES 94923921 T ES94923921 T ES 94923921T ES 94923921 T ES94923921 T ES 94923921T ES 2162867 T3 ES2162867 T3 ES 2162867T3
Authority
ES
Spain
Prior art keywords
pct
therapeutic agent
sec
tablet
xanthan gum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94923921T
Other languages
English (en)
Inventor
Sang K Wong
Patrick Kearney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent Pharma Solutions Inc
Original Assignee
Catalent Pharma Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalent Pharma Solutions Inc filed Critical Catalent Pharma Solutions Inc
Application granted granted Critical
Publication of ES2162867T3 publication Critical patent/ES2162867T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

EN LA PRESENTE INVENCION SE PRESENTA UNA TECNICA MEJORADA PARA LA PREPARACION DE UN COMPRIMIDO FARMACEUTICO DE DISTRIBUCION RAPIDA DE UN AGENTE TERAPEUTICO GRANULAR QUE TIENE TANTO UNA SOLUBILIDAD RELATIVAMENTE BAJA COMO UN TAMAÑO DE LAS PARTICULAS RELATIVAMENTE GRANDE. SE AÑADE GOMA DE XANTANO A UNA MEZCLA LIQUIDA DE SOLVENTE, COMPONENTES DE SOPORTE Y EL AGENTE TERAPEUTICO GRANULAR. LA GOMA DE XANTANO NO SOLO FACILITA LA SUSPENSION DEL AGENTE TERAPEUTICO GRANULAR EN LA MEZCLA LIQUIDA SINO QUE, SORPRENDENTEMENTE, LO HACE SIN QUE LAS PROPIEDADES DE DISPERSION Y TEXTURA DEL COMPRIMIDO SE VEAN AFECTADAS EN LA BOCA DEL PACIENTE TRAS SU ADMINISTRACION.
ES94923921T 1993-07-09 1994-07-08 Metodo de fabricacion de formas de dosificacion de farmacos liofilizados. Expired - Lifetime ES2162867T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8903493A 1993-07-09 1993-07-09

Publications (1)

Publication Number Publication Date
ES2162867T3 true ES2162867T3 (es) 2002-01-16

Family

ID=22215166

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94923921T Expired - Lifetime ES2162867T3 (es) 1993-07-09 1994-07-08 Metodo de fabricacion de formas de dosificacion de farmacos liofilizados.

Country Status (9)

Country Link
US (1) US5631023A (es)
EP (1) EP0804170B1 (es)
JP (1) JP3233638B2 (es)
AT (1) ATE208615T1 (es)
AU (1) AU691195B2 (es)
CA (1) CA2166891C (es)
DE (1) DE69429119T2 (es)
ES (1) ES2162867T3 (es)
WO (1) WO1995001782A2 (es)

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CA2166891C (en) 2001-07-03
ATE208615T1 (de) 2001-11-15
EP0804170B1 (en) 2001-11-14
CA2166891A1 (en) 1995-01-19
DE69429119T2 (de) 2002-07-18
JP3233638B2 (ja) 2001-11-26
JPH09502622A (ja) 1997-03-18
DE69429119D1 (de) 2001-12-20
WO1995001782A2 (en) 1995-01-19
AU691195B2 (en) 1998-05-14
US5631023A (en) 1997-05-20
AU7397394A (en) 1995-02-06
WO1995001782A3 (en) 1995-03-09
EP0804170A2 (en) 1997-11-05

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