CA2259583C - Azolo triazines and pyrimidines - Google Patents

Azolo triazines and pyrimidines Download PDF

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Publication number
CA2259583C
CA2259583C CA002259583A CA2259583A CA2259583C CA 2259583 C CA2259583 C CA 2259583C CA 002259583 A CA002259583 A CA 002259583A CA 2259583 A CA2259583 A CA 2259583A CA 2259583 C CA2259583 C CA 2259583C
Authority
CA
Canada
Prior art keywords
alkyl
compound
formula
nhch
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002259583A
Other languages
English (en)
French (fr)
Other versions
CA2259583A1 (en
Inventor
Liqi He
Paul Joseph Gilligan
Argyrios Georgios Arvanitis
Robert John Chorvat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Pharma Co
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Priority to CA002532925A priority Critical patent/CA2532925C/en
Priority claimed from PCT/US1997/013072 external-priority patent/WO1998003510A1/en
Priority claimed from US08/899,242 external-priority patent/US6124289A/en
Publication of CA2259583A1 publication Critical patent/CA2259583A1/en
Application granted granted Critical
Publication of CA2259583C publication Critical patent/CA2259583C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Coloring (AREA)
CA002259583A 1996-07-24 1997-07-23 Azolo triazines and pyrimidines Expired - Lifetime CA2259583C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002532925A CA2532925C (en) 1996-07-24 1997-07-23 Azolo triazines and pyrimidines

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US2329096P 1996-07-24 1996-07-24
US68604796A 1996-07-24 1996-07-24
US60/686,047 1996-07-24
US60/023,290 1996-07-24
US08/899,242 1997-07-23
PCT/US1997/013072 WO1998003510A1 (en) 1996-07-24 1997-07-23 AZOLO TRIAZINES AND PYRIMIDINES
US08/899,242 US6124289A (en) 1996-07-24 1997-07-23 Azolo triazines and pyrimidines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002532925A Division CA2532925C (en) 1996-07-24 1997-07-23 Azolo triazines and pyrimidines

Publications (2)

Publication Number Publication Date
CA2259583A1 CA2259583A1 (en) 1998-01-29
CA2259583C true CA2259583C (en) 2009-11-17

Family

ID=27362048

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002259583A Expired - Lifetime CA2259583C (en) 1996-07-24 1997-07-23 Azolo triazines and pyrimidines

Country Status (15)

Country Link
JP (2) JP4704521B2 (zh)
CN (3) CN1104432C (zh)
AR (1) AR049583A2 (zh)
BR (1) BR9710544A (zh)
CA (1) CA2259583C (zh)
CZ (1) CZ299451B6 (zh)
EA (1) EA004403B1 (zh)
EE (1) EE04316B1 (zh)
HR (1) HRP970413A2 (zh)
IL (4) IL127871A0 (zh)
NO (1) NO315610B3 (zh)
NZ (1) NZ333777A (zh)
PL (1) PL195762B1 (zh)
SI (1) SI9720045B (zh)
SK (1) SK286461B6 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030125330A1 (en) * 2001-03-13 2003-07-03 Gilligan Paul J. 4 - (2-butylamino) - 2, 7-dimethyl-8- (2-methyl-6-methoxypyrid-3-yl) pyrazolo- [1,5-A] - 1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands
WO2004110454A1 (ja) * 2003-06-13 2004-12-23 Ishihara Sangyo Kaisha, Ltd. アデノシンＡ2ａ受容体アゴニストの投与が必要な疾患を治療又は予防するための組成物
US7329662B2 (en) * 2003-10-03 2008-02-12 Hoffmann-La Roche Inc. Pyrazolo-pyridine
GB0519957D0 (en) * 2005-09-30 2005-11-09 Sb Pharmco Inc Chemical compound
US8030304B2 (en) * 2006-09-20 2011-10-04 Eli Lilly And Company Thiazole pyrazolopyrimidines CRF1 receptor antagonists
CN103694242B (zh) * 2013-12-10 2016-01-06 昆明翔昊科技有限公司 吡唑并嘧啶类化合物及其药物组合物和其在制药中的应用
CN112608316B (zh) * 2019-07-30 2022-10-21 厦门宝太生物科技股份有限公司 一种吡唑并三嗪类腺苷受体拮抗剂
BR112023002497A2 (pt) 2020-08-12 2023-05-02 Spruce Biosciences Inc Métodos e composições para tratamento da síndrome dos ovários policísticos
US11708372B2 (en) 2021-11-19 2023-07-25 Spruce Biosciences, Inc. Crystalline composition of tildacerfont and methods of use and preparation thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3995039A (en) * 1975-05-27 1976-11-30 Merck & Co., Inc. Pyrazolo [1,5-a] [1,3,5] triazines
JPS6157587A (ja) * 1984-08-29 1986-03-24 Shionogi & Co Ltd 縮合複素環誘導体および抗潰瘍剤
US4824834A (en) * 1986-10-31 1989-04-25 Otsuka Pharmaceutical Company, Limited Pyrazolotriazine compounds
JP2691317B2 (ja) * 1989-08-25 1997-12-17 株式会社大塚製薬工場 ４―ヒドロキシ―８―（３―低級アルコキシ―４―フェニルスルフィニルフェニル）ピラゾロ〔１，５―ａ〕―１，３，５―トリアジン光学活性体の塩類及びその製造方法
US5420128A (en) * 1990-10-09 1995-05-30 Otsuka Pharmaceutical Co., Ltd. Pyrimidine derivatives, method of manufacturing the same, and androgen inhibitor
KR100191774B1 (ko) * 1991-04-22 1999-06-15 오스카 아끼히꼬 피라졸로[1,5-알파] 피리미딘 유도체 및 이것을 함유하는 항염증제
US5356897A (en) * 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines

Also Published As

Publication number Publication date
NZ333777A (en) 2000-07-28
NO990264L (no) 1999-03-10
JP2005097257A (ja) 2005-04-14
SI9720045A (sl) 1999-10-31
CA2259583A1 (en) 1998-01-29
EE04316B1 (et) 2004-06-15
CZ18499A3 (cs) 1999-11-17
AR049583A2 (es) 2006-08-16
NO990264D0 (no) 1999-01-21
HRP970413A2 (en) 1998-10-31
PL195762B1 (pl) 2007-10-31
CN1250223C (zh) 2006-04-12
EE9900019A (et) 1999-08-16
BR9710544A (pt) 1999-08-17
IL150163A (en) 2010-12-30
SK286461B6 (sk) 2008-10-07
SI9720045B (sl) 2008-02-29
JP2002513382A (ja) 2002-05-08
JP4704521B2 (ja) 2011-06-15
IL164513A0 (en) 2005-12-18
IL164513A (en) 2010-04-29
CN1104432C (zh) 2003-04-02
NO315610B1 (no) 2003-09-29
PL331523A1 (en) 1999-07-19
EA004403B1 (ru) 2004-04-29
CN1225637A (zh) 1999-08-11
IL127871A (en) 2010-04-29
IL127871A0 (en) 1999-10-28
EA199900158A1 (ru) 1999-10-28
CN1327793A (zh) 2001-12-26
SK9799A3 (sk) 2005-04-01
NO315610B3 (no) 2003-09-29
CN1388126A (zh) 2003-01-01
JP4194539B2 (ja) 2008-12-10
CZ299451B6 (cs) 2008-07-30

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Effective date: 20170724