CA2259583C - Azolo triazines and pyrimidines - Google Patents

Azolo triazines and pyrimidines Download PDF

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Publication number
CA2259583C
CA2259583C CA002259583A CA2259583A CA2259583C CA 2259583 C CA2259583 C CA 2259583C CA 002259583 A CA002259583 A CA 002259583A CA 2259583 A CA2259583 A CA 2259583A CA 2259583 C CA2259583 C CA 2259583C
Authority
CA
Canada
Prior art keywords
alkyl
compound
formula
nhch
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002259583A
Other languages
English (en)
French (fr)
Other versions
CA2259583A1 (en
Inventor
Liqi He
Paul Joseph Gilligan
Argyrios Georgios Arvanitis
Robert John Chorvat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Pharma Co
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Priority to CA002532925A priority Critical patent/CA2532925C/en
Priority claimed from US08/899,242 external-priority patent/US6124289A/en
Priority claimed from PCT/US1997/013072 external-priority patent/WO1998003510A1/en
Publication of CA2259583A1 publication Critical patent/CA2259583A1/en
Application granted granted Critical
Publication of CA2259583C publication Critical patent/CA2259583C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Detergent Compositions (AREA)
  • Coloring (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CA002259583A 1996-07-24 1997-07-23 Azolo triazines and pyrimidines Expired - Lifetime CA2259583C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002532925A CA2532925C (en) 1996-07-24 1997-07-23 Azolo triazines and pyrimidines

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US2329096P 1996-07-24 1996-07-24
US68604796A 1996-07-24 1996-07-24
US60/686,047 1996-07-24
US60/023,290 1996-07-24
US08/899,242 US6124289A (en) 1996-07-24 1997-07-23 Azolo triazines and pyrimidines
PCT/US1997/013072 WO1998003510A1 (en) 1996-07-24 1997-07-23 AZOLO TRIAZINES AND PYRIMIDINES
US08/899,242 1997-07-23

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002532925A Division CA2532925C (en) 1996-07-24 1997-07-23 Azolo triazines and pyrimidines

Publications (2)

Publication Number Publication Date
CA2259583A1 CA2259583A1 (en) 1998-01-29
CA2259583C true CA2259583C (en) 2009-11-17

Family

ID=27362048

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002259583A Expired - Lifetime CA2259583C (en) 1996-07-24 1997-07-23 Azolo triazines and pyrimidines

Country Status (15)

Country Link
JP (2) JP4704521B2 (zh)
CN (3) CN1104432C (zh)
AR (1) AR049583A2 (zh)
BR (1) BR9710544A (zh)
CA (1) CA2259583C (zh)
CZ (1) CZ299451B6 (zh)
EA (1) EA004403B1 (zh)
EE (1) EE04316B1 (zh)
HR (1) HRP970413A2 (zh)
IL (4) IL127871A0 (zh)
NO (1) NO315610B1 (zh)
NZ (1) NZ333777A (zh)
PL (1) PL195762B1 (zh)
SI (1) SI9720045B (zh)
SK (1) SK286461B6 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1368094T3 (da) * 2001-03-13 2007-07-02 Bristol Myers Squibb Pharma Co 4-(2-Butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl)-pyrazolo[1,5-a]-1,3,5-triazin, dens enantiomerer og farmaceutisk acceptable salte som corticotropin-frigivende faktor-receptor- ligander
WO2004110454A1 (ja) * 2003-06-13 2004-12-23 Ishihara Sangyo Kaisha, Ltd. アデノシンＡ2ａ受容体アゴニストの投与が必要な疾患を治療又は予防するための組成物
US7329662B2 (en) * 2003-10-03 2008-02-12 Hoffmann-La Roche Inc. Pyrazolo-pyridine
GB0519957D0 (en) * 2005-09-30 2005-11-09 Sb Pharmco Inc Chemical compound
KR101088239B1 (ko) * 2006-09-20 2011-11-30 일라이 릴리 앤드 캄파니 Ｃｒｆ１ 수용체 길항제로서의 티아졸 피라졸로피리미딘
CN103694242B (zh) * 2013-12-10 2016-01-06 昆明翔昊科技有限公司 吡唑并嘧啶类化合物及其药物组合物和其在制药中的应用
CN112479956A (zh) * 2019-07-30 2021-03-12 杭州阿诺生物医药科技有限公司 一种用于制备腺苷受体抑制剂中间体的方法
KR20240023691A (ko) 2020-08-12 2024-02-22 스프루스 바이오사이언시스 인코포레이티드 다낭성 난소 증후군을 치료하기 위한 방법 및 조성물
US11708372B2 (en) 2021-11-19 2023-07-25 Spruce Biosciences, Inc. Crystalline composition of tildacerfont and methods of use and preparation thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3995039A (en) * 1975-05-27 1976-11-30 Merck & Co., Inc. Pyrazolo [1,5-a] [1,3,5] triazines
JPS6157587A (ja) * 1984-08-29 1986-03-24 Shionogi & Co Ltd 縮合複素環誘導体および抗潰瘍剤
US4824834A (en) * 1986-10-31 1989-04-25 Otsuka Pharmaceutical Company, Limited Pyrazolotriazine compounds
JP2691317B2 (ja) * 1989-08-25 1997-12-17 株式会社大塚製薬工場 ４―ヒドロキシ―８―（３―低級アルコキシ―４―フェニルスルフィニルフェニル）ピラゾロ〔１，５―ａ〕―１，３，５―トリアジン光学活性体の塩類及びその製造方法
WO1992006096A1 (en) * 1990-10-09 1992-04-16 Otsuka Pharmaceutical Co., Ltd. Pyrimidine derivative, production thereof, and androgen inhibitor
DK0591528T3 (da) * 1991-04-22 1999-08-23 Otsuka Pharma Co Ltd Pyrazolo[1,5-a]pyrimidinderivat og antiinflammatorisk middel, der indeholder dette
US5356897A (en) * 1991-09-09 1994-10-18 Fujisawa Pharmaceutical Co., Ltd. 3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines

Also Published As

Publication number Publication date
CN1225637A (zh) 1999-08-11
JP2005097257A (ja) 2005-04-14
SK286461B6 (sk) 2008-10-07
PL195762B1 (pl) 2007-10-31
NZ333777A (en) 2000-07-28
CZ299451B6 (cs) 2008-07-30
CN1327793A (zh) 2001-12-26
CN1388126A (zh) 2003-01-01
PL331523A1 (en) 1999-07-19
EA004403B1 (ru) 2004-04-29
CN1250223C (zh) 2006-04-12
CN1104432C (zh) 2003-04-02
NO990264D0 (no) 1999-01-21
JP2002513382A (ja) 2002-05-08
AR049583A2 (es) 2006-08-16
NO315610B3 (no) 2003-09-29
SK9799A3 (sk) 2005-04-01
JP4704521B2 (ja) 2011-06-15
EE9900019A (et) 1999-08-16
IL127871A (en) 2010-04-29
CA2259583A1 (en) 1998-01-29
EE04316B1 (et) 2004-06-15
HRP970413A2 (en) 1998-10-31
CZ18499A3 (cs) 1999-11-17
EA199900158A1 (ru) 1999-10-28
NO990264L (no) 1999-03-10
JP4194539B2 (ja) 2008-12-10
IL127871A0 (en) 1999-10-28
IL164513A0 (en) 2005-12-18
SI9720045B (sl) 2008-02-29
IL150163A (en) 2010-12-30
IL164513A (en) 2010-04-29
BR9710544A (pt) 1999-08-17
NO315610B1 (no) 2003-09-29
SI9720045A (sl) 1999-10-31

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Effective date: 20170724