CA2121499C - Liquid aspirating method - Google Patents
Liquid aspirating methodInfo
- Publication number
- CA2121499C CA2121499C CA002121499A CA2121499A CA2121499C CA 2121499 C CA2121499 C CA 2121499C CA 002121499 A CA002121499 A CA 002121499A CA 2121499 A CA2121499 A CA 2121499A CA 2121499 C CA2121499 C CA 2121499C
- Authority
- CA
- Canada
- Prior art keywords
- aspirating
- nozzle tip
- red blood
- volume
- blood plasma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 48
- 238000000034 method Methods 0.000 title claims description 39
- 238000012544 monitoring process Methods 0.000 claims description 3
- 210000003743 erythrocyte Anatomy 0.000 abstract description 51
- 210000004369 blood Anatomy 0.000 abstract description 33
- 239000008280 blood Substances 0.000 abstract description 33
- 210000002381 plasma Anatomy 0.000 description 62
- 230000008569 process Effects 0.000 description 24
- 206010003504 Aspiration Diseases 0.000 description 23
- 238000012360 testing method Methods 0.000 description 20
- 238000000576 coating method Methods 0.000 description 16
- 239000011248 coating agent Substances 0.000 description 14
- 239000003085 diluting agent Substances 0.000 description 14
- 238000007865 diluting Methods 0.000 description 7
- 230000004520 agglutination Effects 0.000 description 4
- 238000005119 centrifugation Methods 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 210000000265 leukocyte Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 210000000601 blood cell Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
- G01N35/109—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N2035/1025—Fluid level sensing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
Landscapes
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3271482A JP2515938B2 (ja) | 1991-10-18 | 1991-10-18 | 液体の吸引方法 |
| JP271482/91 | 1991-10-18 | ||
| PCT/JP1992/001344 WO1993008476A1 (en) | 1991-10-18 | 1992-10-15 | Method of sucking liquid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2121499A1 CA2121499A1 (en) | 1993-04-29 |
| CA2121499C true CA2121499C (en) | 1999-12-14 |
Family
ID=17500663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002121499A Expired - Fee Related CA2121499C (en) | 1991-10-18 | 1992-10-15 | Liquid aspirating method |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5488874A (Sortimente) |
| EP (1) | EP0608423B1 (Sortimente) |
| JP (1) | JP2515938B2 (Sortimente) |
| AU (1) | AU664390B2 (Sortimente) |
| CA (1) | CA2121499C (Sortimente) |
| DE (1) | DE69220499T2 (Sortimente) |
| TW (1) | TW221670B (Sortimente) |
| WO (1) | WO1993008476A1 (Sortimente) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06331632A (ja) * | 1993-05-19 | 1994-12-02 | Sutatsuku Syst:Kk | サンプリング分注装置およびその吸入異常判定方法 |
| US6158269A (en) * | 1995-07-13 | 2000-12-12 | Bayer Corporation | Method and apparatus for aspirating and dispensing sample fluids |
| US5750881A (en) * | 1995-07-13 | 1998-05-12 | Chiron Diagnostics Corporation | Method and apparatus for aspirating and dispensing sample fluids |
| US5915282A (en) * | 1995-12-14 | 1999-06-22 | Abbott Laboratories | Fluid handler and method of handling a fluid |
| US5965828A (en) * | 1995-12-14 | 1999-10-12 | Abbott Laboratories | Fluid handler and method of handling a fluid |
| US5723795A (en) * | 1995-12-14 | 1998-03-03 | Abbott Laboratories | Fluid handler and method of handling a fluid |
| JP3492870B2 (ja) | 1996-11-20 | 2004-02-03 | 株式会社日立製作所 | 自動分析装置 |
| US6121049A (en) * | 1997-12-05 | 2000-09-19 | Bayer Corporation | Method of verifying aspirated volume in automatic diagnostic system |
| US6060320A (en) * | 1997-12-05 | 2000-05-09 | Bayer Corporation | Method of verifying aspirated volume in automatic diagnostic system |
| JP2000121511A (ja) * | 1998-10-13 | 2000-04-28 | Hitachi Koki Co Ltd | 自動分離抽出装置及びその制御方法 |
| US6689323B2 (en) * | 1998-10-30 | 2004-02-10 | Agilent Technologies | Method and apparatus for liquid transfer |
| JP4045475B2 (ja) * | 1999-09-06 | 2008-02-13 | 東洋紡績株式会社 | 核酸・蛋白質精製装置 |
| DE19946525A1 (de) * | 1999-09-28 | 2001-05-03 | Fraunhofer Ges Forschung | Vorrichtung zur Aufnahme und Abgabe kleinster Flüssigkeitsmengen |
| US6370942B1 (en) | 2000-05-15 | 2002-04-16 | Dade Behring Inc. | Method for verifying the integrity of a fluid transfer |
| US6393898B1 (en) * | 2000-05-25 | 2002-05-28 | Symyx Technologies, Inc. | High throughput viscometer and method of using same |
| ATE313805T1 (de) * | 2001-03-09 | 2006-01-15 | Hamilton Bonaduz Ag | Verfahren und vorrichtung zur beurteilung eines flüssigkeitsdosierungsvorgangs |
| DE10210908A1 (de) * | 2002-03-05 | 2003-12-04 | Alfred Nordheim | Vorrichtung zum Aufbringen von flüssigen Medien und Verfahren dazu |
| DE102004063358A1 (de) * | 2004-12-23 | 2006-07-06 | Georg-August-Universität Göttingen | Verfahren zur Bestimmung der Viskosität und Viskosimeter |
| US7998751B2 (en) * | 2005-04-26 | 2011-08-16 | Siemens Healthcare Diagnostics Inc. | Method and apparatus for aspirating and dispensing small liquid samples in an automated clinical analyzer |
| US7477997B2 (en) | 2005-12-19 | 2009-01-13 | Siemens Healthcare Diagnostics Inc. | Method for ascertaining interferants in small liquid samples in an automated clinical analyzer |
| DE102005060862B3 (de) * | 2005-12-20 | 2007-06-28 | Stratec Biomedical Systems Ag | Verfahren und Vorrichtung zur Beurteilung eines Dosiervorgangs |
| JP2009025248A (ja) * | 2007-07-23 | 2009-02-05 | Olympus Corp | 自動分析装置及び分注方法 |
| US7634378B2 (en) * | 2007-11-30 | 2009-12-15 | Siemens Healthcare Diagnostics Inc. | Detection of insufficient sample during aspiration with a pipette |
| JP5305794B2 (ja) * | 2008-09-05 | 2013-10-02 | 株式会社東芝 | 自動分析装置 |
| US8307697B2 (en) * | 2010-04-14 | 2012-11-13 | Ortho-Clinical Diagnostics, Inc. | Method for estimating viscosity |
| JP2012021892A (ja) * | 2010-07-15 | 2012-02-02 | Hitachi High-Technologies Corp | 自動分析装置及び分注方法 |
| US9494496B2 (en) | 2011-07-08 | 2016-11-15 | Hitachi High-Technologies Corporation | Solid-phase extraction apparatus and viscosity measurement apparatus |
| JP6635661B2 (ja) * | 2015-02-26 | 2020-01-29 | 株式会社日立ハイテクノロジーズ | 自動分析装置及び試料希釈攪拌方法 |
| GB201601667D0 (en) * | 2016-01-29 | 2016-03-16 | Ge Healthcare Bio Sciences Ab | Improvements in and relating to liquid fraction collectors |
| EP3502656B1 (en) * | 2017-12-22 | 2022-09-21 | Tecan Trading Ag | A pipetting apparatus, a liquid handling system and a method of controlling pipetting |
| JP6946202B2 (ja) * | 2018-01-15 | 2021-10-06 | 株式会社日立ハイテク | 自動分析装置 |
| JP7245135B2 (ja) * | 2019-09-03 | 2023-03-23 | 京セラ株式会社 | プレウォッシュ方法、液体吸引装置及びピペット |
| EP4296684A1 (en) * | 2022-06-20 | 2023-12-27 | Tecan Trading AG | Liquid interface estimation for liquid aspiration |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3999538A (en) * | 1975-05-22 | 1976-12-28 | Buren Philpot V Jun | Method of blood viscosity determination |
| JPS56130658A (en) * | 1980-03-19 | 1981-10-13 | Olympus Optical Co Ltd | Dispenser |
| JPS56164957A (en) * | 1980-05-23 | 1981-12-18 | Aloka Co Ltd | Automatic dispenser |
| JPS5847164U (ja) * | 1981-09-22 | 1983-03-30 | 東亜医用電子株式会社 | 自動希釈装置 |
| JPS58105066A (ja) * | 1981-12-17 | 1983-06-22 | Toshiba Corp | 自動化学分析装置における吸引吐出装置 |
| JPS5980661A (ja) * | 1982-10-29 | 1984-05-10 | Sumitomo Chem Co Ltd | N−フエニルテトラヒドロフタルイミド誘導体、その製造法およびそれを有効成分とする除草剤 |
| JPS60165552A (ja) * | 1984-02-09 | 1985-08-28 | Toshiba Corp | 生化学自動分析装置 |
| JPS60207062A (ja) * | 1984-03-31 | 1985-10-18 | Toshiba Corp | 自動化学分析装置における吸引吐出装置 |
| JPS60224071A (ja) * | 1984-04-20 | 1985-11-08 | Sankyo Co Ltd | 試薬などのピペツテイング方法 |
| JPS6154427A (ja) * | 1984-08-27 | 1986-03-18 | Mitsui Petrochem Ind Ltd | 高粘度液体に好適な自動粘度測定装置 |
| US4675301A (en) * | 1985-04-01 | 1987-06-23 | Eastman Kodak Company | Method for correcting for changes in air pressure above a liquid to be dispensed from a container mounted on a probe |
| JPS6375565A (ja) * | 1986-09-18 | 1988-04-05 | Toshiba Corp | サンプリングモニタ |
| KR920003040B1 (ko) * | 1989-11-27 | 1992-04-13 | 주식회사 에스케이씨 | 자동점도 측정장치 |
| JPH06154427A (ja) * | 1992-11-24 | 1994-06-03 | Mukai Masami | ダイエット支援玩具 |
-
1991
- 1991-10-18 JP JP3271482A patent/JP2515938B2/ja not_active Expired - Lifetime
-
1992
- 1992-10-12 TW TW081108078A patent/TW221670B/zh active
- 1992-10-15 EP EP92921476A patent/EP0608423B1/en not_active Expired - Lifetime
- 1992-10-15 DE DE69220499T patent/DE69220499T2/de not_active Expired - Fee Related
- 1992-10-15 WO PCT/JP1992/001344 patent/WO1993008476A1/ja not_active Ceased
- 1992-10-15 AU AU27718/92A patent/AU664390B2/en not_active Expired - Fee Related
- 1992-10-15 CA CA002121499A patent/CA2121499C/en not_active Expired - Fee Related
- 1992-10-15 US US08/211,802 patent/US5488874A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU664390B2 (en) | 1995-11-16 |
| DE69220499D1 (de) | 1997-07-24 |
| TW221670B (Sortimente) | 1994-03-11 |
| US5488874A (en) | 1996-02-06 |
| EP0608423A4 (en) | 1994-11-23 |
| EP0608423A1 (en) | 1994-08-03 |
| EP0608423B1 (en) | 1997-06-18 |
| WO1993008476A1 (en) | 1993-04-29 |
| JP2515938B2 (ja) | 1996-07-10 |
| CA2121499A1 (en) | 1993-04-29 |
| DE69220499T2 (de) | 1997-10-16 |
| AU2771892A (en) | 1993-05-21 |
| JPH05107253A (ja) | 1993-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |