CA2028830A1 - Dispositif relie a un inhalateur - Google Patents

Dispositif relie a un inhalateur

Info

Publication number
CA2028830A1
CA2028830A1 CA2028830A CA2028830A CA2028830A1 CA 2028830 A1 CA2028830 A1 CA 2028830A1 CA 2028830 A CA2028830 A CA 2028830A CA 2028830 A CA2028830 A CA 2028830A CA 2028830 A1 CA2028830 A1 CA 2028830A1
Authority
CA
Canada
Prior art keywords
inhaler
inhalation
connection
airflow
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2028830A
Other languages
English (en)
Other versions
CA2028830C (fr
Inventor
Jan Anders Roland Andersson
Nils Goran Nilsson
Per-Olof Stefan Fagerstrom
Thomas Mikael Wendel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Draco AB
Original Assignee
Jan Anders Roland Andersson
Nils Goran Nilsson
Per-Olof Stefan Fagerstrom
Thomas Mikael Wendel
Aktiebolaget Draco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jan Anders Roland Andersson, Nils Goran Nilsson, Per-Olof Stefan Fagerstrom, Thomas Mikael Wendel, Aktiebolaget Draco filed Critical Jan Anders Roland Andersson
Publication of CA2028830A1 publication Critical patent/CA2028830A1/fr
Application granted granted Critical
Publication of CA2028830C publication Critical patent/CA2028830C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0418Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3375Acoustical, e.g. ultrasonic, measuring means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/43General characteristics of the apparatus making noise when used correctly
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/14Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Electrodes Of Semiconductors (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
  • Saccharide Compounds (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • External Artificial Organs (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne un dispositif pour inhalateur, destiné à mesurer et à enregistrer l'inhalation d'un patient. Ledit dispositifest destiné à une utilisation dans des médications par exemple dans des tests cliniques, dans lesquels il est nécessaire de pouvoir procéder à un contrôle a posteriori, afin de savoir si le patient a pris des médicaments selon la prescription établie. Ledit dispositif comprend une unité électronique, disposée dans ledit inhalateur, permettant d'enregistrer le temps de chaque posologie des médicaments dudit inhalateur. On a prévu un détecteur (16, 32, 36) dans ledit inhalateur, disposé dans un passage d'écoulement d'air de l'inhalation, ledit détecteur détectant l'écoulement d'air de l'inhalation dans ledit inhalateur, ainsi que la quantité de médicament disponible lors de l'inhalation, de sorte qu'une combinaison de ces deux valeurs détectées détermine si et comment l'inhalation effectuée, doit être enregistrée dans ladite unité électronique (11, 33, 35).
CA 2028830 1989-03-07 1990-03-02 Dispositif relie a un inhalateur Expired - Lifetime CA2028830C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE8900793-4 1989-03-07
SE8900793A SE466684B (sv) 1989-03-07 1989-03-07 Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
PCT/SE1990/000137 WO1990010470A1 (fr) 1989-03-07 1990-03-02 Dispositif pour inhalateur

Publications (2)

Publication Number Publication Date
CA2028830A1 true CA2028830A1 (fr) 1990-09-08
CA2028830C CA2028830C (fr) 2000-02-08

Family

ID=20375263

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2028830 Expired - Lifetime CA2028830C (fr) 1989-03-07 1990-03-02 Dispositif relie a un inhalateur

Country Status (16)

Country Link
US (1) US5331953A (fr)
EP (1) EP0387222B1 (fr)
JP (1) JP2927541B2 (fr)
KR (1) KR0135309B1 (fr)
AT (1) ATE91911T1 (fr)
AU (1) AU613264B2 (fr)
CA (1) CA2028830C (fr)
DE (1) DE69002353T2 (fr)
DK (1) DK0387222T3 (fr)
ES (1) ES2042267T3 (fr)
FI (1) FI102948B1 (fr)
IE (1) IE64129B1 (fr)
NO (1) NO175289C (fr)
PT (1) PT93347B (fr)
SE (1) SE466684B (fr)
WO (1) WO1990010470A1 (fr)

Families Citing this family (223)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1240750B (it) * 1990-04-12 1993-12-17 Chiesi Farma Spa Dispositivo per la somministrazione di sostanze medicamentose in polvere
AU9089591A (en) * 1990-12-17 1992-07-22 Minnesota Mining And Manufacturing Company Inhaler
IT1248059B (it) * 1991-06-14 1995-01-05 Miat Spa Insufflatore multidose per farmaci in polvere
ES2141108T3 (es) * 1991-07-02 2000-03-16 Inhale Inc Metodo y dispositivo para proporcionar medicamentos en aerosol.
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
EP0610240A1 (fr) * 1991-09-26 1994-08-17 Schering Corporation Inhalateur pour medicaments en aerosol
US5363842A (en) * 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
DE59307510D1 (de) * 1992-05-29 1997-11-13 Ggu Gesundheits Umweltforsch Vorrichtung zur erzeugung inhalierbarer wirkstoffpartikel
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
GB2273660B (en) * 1992-09-11 1996-07-17 Aid Medic Ltd Drug delivery arrangement
MY115140A (en) * 1992-12-18 2003-04-30 Schering Corp Inhaler for powdered medications
AU6167894A (en) * 1993-01-29 1994-08-15 Miris Medical Corporation Intrapulmonary delivery of hormones
US5505195A (en) * 1993-09-16 1996-04-09 Medtrac Technologies Inc. Dry powder inhalant device with dosage and air flow monitor
US5505192A (en) * 1993-11-12 1996-04-09 New-Med Corporation Dispenser monitoring system
DE4422710C1 (de) * 1994-06-29 1995-09-14 Boehringer Ingelheim Kg Inhalationsgerät mit einem Elektronikmodul zur Funktionsüberwachung
US6390088B1 (en) 1993-12-13 2002-05-21 Boehringer Ingelheim Kg Aerosol inhaler
DE4400084C2 (de) * 1994-01-04 2001-08-02 Softec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester in einem Luftstrom fein verteilter Form
ES2218543T3 (es) 1994-03-07 2004-11-16 Nektar Therapeutics Procedimiento y preparacion para la administracion de insulina por via pulmonar.
US6051256A (en) * 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
SE9401020D0 (sv) * 1994-03-25 1994-03-25 Astra Ab Method and apparatus in connection with an inhaler
US5839429A (en) * 1994-03-25 1998-11-24 Astra Aktiebolag Method and apparatus in connection with an inhaler
AU124387S (en) * 1994-03-25 1995-08-11 Astra Ab Training device for an inhaler
AU697676B2 (en) 1994-09-21 1998-10-15 Nektar Therapeutics Apparatus and methods for dispersing dry powder medicaments
DE69507321T2 (de) * 1994-10-24 1999-07-15 Powderject Res Ltd Nadellose spritze
DE4440734A1 (de) * 1994-11-15 1996-05-23 Bayer Ag Abscheidesystem für einen Pulverinhalator
US5507278A (en) * 1994-11-18 1996-04-16 Karell; Manuel L. Tongue-guard for inhaler
US5495848A (en) * 1994-11-25 1996-03-05 Nellcar Puritan Bennett Monitoring system for delivery of therapeutic gas
US5622163A (en) * 1994-11-29 1997-04-22 Iep Group, Inc. Counter for fluid dispensers
US5544647A (en) * 1994-11-29 1996-08-13 Iep Group, Inc. Metered dose inhalator
SE9404140D0 (sv) * 1994-11-29 1994-11-29 Astra Ab Dose indicating device
DE19500764C2 (de) * 1995-01-13 2001-09-27 Sofotec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form
US5758637A (en) * 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US6085740A (en) 1996-02-21 2000-07-11 Aerogen, Inc. Liquid dispensing apparatus and methods
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
SE9502800D0 (sv) * 1995-08-10 1995-08-10 Astra Ab Disposable inhaler
JP3317823B2 (ja) 1995-08-11 2002-08-26 株式会社ユニシアジェックス 投薬器
US5649554A (en) * 1995-10-16 1997-07-22 Philip Morris Incorporated Electrical lighter with a rotatable tobacco supply
US5724986A (en) * 1995-11-06 1998-03-10 Jones Medical Instrument Co. Casing and spirometer for metered dose inhaler
EP0865302B1 (fr) * 1995-12-07 2000-05-31 Jago Pharma Ag Inhalateur fournissant des doses multiples d'une poudre seche pharmacologique
US7131441B1 (en) 1995-12-07 2006-11-07 Skyepharma Ag Inhaler for multiple dosed administration of a pharmacological dry powder
RU2195965C2 (ru) * 1996-02-21 2003-01-10 Шеринг Корпорейшн Устройство для ингаляции порошка
US5890490A (en) * 1996-11-29 1999-04-06 Aylsworth; Alonzo C. Therapeutic gas flow monitoring system
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
GB9700226D0 (en) * 1997-01-08 1997-02-26 Glaxo Group Ltd Inhalation device
SE9700948D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler X
SE9700940D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler IV
SE9700938D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler II and a method of construction thereof
TW469832U (en) * 1997-03-14 2001-12-21 Astra Ab Inhalation device
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5911219A (en) * 1997-04-18 1999-06-15 Aylsworth; Alonzo C. Therapeutic gas flow meter and monitor
TW533865U (en) 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
CA2212430A1 (fr) * 1997-08-07 1999-02-07 George Volgyesi Appareil inhalateur
NZ504021A (en) * 1997-10-17 2003-04-29 Systemic Pulmonary Delivery Lt Method and apparatus for delivering aerosolized medication having air discharged through air tube directly into plume of aerosolized medication
IT238038Y1 (it) * 1997-11-12 2000-09-29 Miat Spa Erogatore multidose di una sostanza in polvere o in grani,del tipo incui l'approntamento di una dose comporta la rotazione di un alberino
US6142339A (en) 1998-01-16 2000-11-07 1263152 Ontario Inc. Aerosol dispensing device
DE69918267T2 (de) 1998-01-16 2005-07-28 1263152 Ontario Inc., London Anzeigevorrichtung zur verwendung mit einer abgabevorrichtung
US6358058B1 (en) 1998-01-30 2002-03-19 1263152 Ontario Inc. Aerosol dispensing inhaler training device
JP3488620B2 (ja) * 1998-02-05 2004-01-19 株式会社日立ユニシアオートモティブ 吸入式投薬器
AU138849S (en) * 1998-03-30 1999-11-22 Astra Ab Inhaler with cap
SE9801114D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
US6082358A (en) 1998-05-05 2000-07-04 1263152 Ontario Inc. Indicating device for aerosol container
US6336453B1 (en) 1999-04-30 2002-01-08 Trudell Medical International Indicating device for aerosol container
US6729330B2 (en) 1998-05-05 2004-05-04 Trudell Medical International Indicating device for aerosol container
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
AU2003231650B2 (en) * 1998-06-12 2004-12-02 Microdose Therapeutx, Inc. Metering, packaging and delivery of pharmaceuticals and drugs
US6152130A (en) * 1998-06-12 2000-11-28 Microdose Technologies, Inc. Inhalation device with acoustic control
CA2334590C (fr) * 1998-06-12 2009-08-18 Microdose Technologies, Inc. Dosage, emballage et administration de substances pharmaceutiques et de medicaments
US6142146A (en) * 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device
US6260549B1 (en) 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
AU5970899A (en) 1998-08-28 2000-03-21 Glaxo Group Limited Dispenser
US6223744B1 (en) 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
US6546927B2 (en) 2001-03-13 2003-04-15 Aerogen, Inc. Methods and apparatus for controlling piezoelectric vibration
US6745760B2 (en) 2001-05-15 2004-06-08 Trudell Medical International Medicament applicator
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
EP1450885B1 (fr) 2001-09-28 2015-04-22 Kurve Technology, Inc. Nebuliseur nasal
US7360536B2 (en) 2002-01-07 2008-04-22 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
JP4761709B2 (ja) 2002-01-15 2011-08-31 エアロジェン,インコーポレイテッド エアロゾル発生器を作動するための方法およびシステム
ES2425392T3 (es) 2002-03-20 2013-10-15 Mannkind Corporation Cartucho para un aparato de inhalación
US7004164B2 (en) 2002-03-21 2006-02-28 Trudell Medical International Indicating device for aerosol container
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
US7582284B2 (en) * 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US6830046B2 (en) 2002-04-29 2004-12-14 Hewlett-Packard Development Company, L.P. Metered dose inhaler
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
AU2003249623A1 (en) 2002-05-09 2003-12-12 Kurve Technology, Inc. Particle dispersion chamber for nasal nebulizer
US20030221687A1 (en) * 2002-05-09 2003-12-04 William Kaigler Medication and compliance management system and method
ES2572770T3 (es) 2002-05-20 2016-06-02 Novartis Ag Aparato para proporcionar pulverización para tratamiento médico y métodos
EP2497513B8 (fr) * 2002-09-16 2015-12-16 Sanofi SA Inhalateur de substances en poudre, en particulier de substances médicales
US6886557B2 (en) * 2002-10-31 2005-05-03 Hewlett-Packard Development Company, L.P. Inhalation device and method for delivering variable amounts of different components
US7275534B2 (en) * 2003-01-31 2007-10-02 Hewlett-Packard Development Company, L.P. Medicament ejector with ejection port servicing
US7726303B2 (en) * 2003-02-25 2010-06-01 Hewlett-Packard Development Company, L.P. Controlled medicament ejection
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
GB2398065A (en) * 2003-10-16 2004-08-11 Bespak Plc Dispensing apparatus
US7621273B2 (en) 2003-10-28 2009-11-24 Trudell Medical International Indicating device with warning dosage indicator
US7100530B2 (en) 2003-12-15 2006-09-05 Trudell Medical International, Inc. Dose indicating device
US7467630B2 (en) * 2004-02-11 2008-12-23 Hewlett-Packard Development Company, L.P. Medicament dispenser
US7481213B2 (en) * 2004-02-11 2009-01-27 Hewlett-Packard Development Company, L.P. Medicament dispenser
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
JP4682554B2 (ja) * 2004-07-30 2011-05-11 横浜ゴム株式会社 シーリング材組成物
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
PL1791542T3 (pl) 2004-08-23 2015-11-30 Mannkind Corp Sole diketopiperazyny do dostarczania leków
US7543582B2 (en) 2004-09-20 2009-06-09 Trudell Medical International Dose indicating device with display elements attached to container
ATE452671T1 (de) 2004-10-21 2010-01-15 Novo Nordisk As Injektionsvorrichtung mit einem prozessor zur sammlung von ausstossinformationen
EP1827537B1 (fr) 2004-10-21 2019-08-14 Novo Nordisk A/S Dispositif de délivrance d'un médicament avec un détecteur délivrant un signal indicatif d'une dose éjectée.
CN101810901B (zh) 2005-01-20 2013-07-24 特鲁德尔医学国际公司 分配装置
US20090050139A1 (en) * 2005-03-30 2009-02-26 Canon Kabushiki Kaisha Liquid medicine ejection device
US8912908B2 (en) 2005-04-28 2014-12-16 Proteus Digital Health, Inc. Communication system with remote activation
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
US8836513B2 (en) 2006-04-28 2014-09-16 Proteus Digital Health, Inc. Communication system incorporated in an ingestible product
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
EP2460475A3 (fr) 2005-05-03 2013-02-27 The University of Western Ontario Dispositif buccal et kit pour une utilisation en association avec celui-ci
US9108211B2 (en) 2005-05-25 2015-08-18 Nektar Therapeutics Vibration systems and methods
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
EP2497484A3 (fr) 2006-02-22 2012-11-07 MannKind Corporation Procédé pour améliorer les propriétés pharmaceutiques de microparticules comprenant de la dicétopipérazine et un agent actif
KR100638340B1 (ko) * 2006-03-15 2006-10-27 송인호 낙곡 회수용 흡입기
AU2007228715B2 (en) 2006-03-20 2011-11-17 Novo Nordisk A/S Electronic module for mechanical medication delivery devices
JP5241714B2 (ja) 2006-07-07 2013-07-17 プロテウス デジタル ヘルス, インコーポレイテッド スマートな非経口送達システム
US8141550B2 (en) 2006-08-01 2012-03-27 Trudell Medical International Dispensing device
US20080058772A1 (en) * 2006-08-31 2008-03-06 Robertson Timothy L Personal paramedic
MX2009008582A (es) 2007-02-11 2009-10-30 Map Pharmaceuticals Inc Metodo para la administracion terapeutica de dihidroergotamina para permitir un rapido alivio de la migraña mientras se minimiza el perfil de efectos secundarios.
US7907477B2 (en) * 2007-03-02 2011-03-15 Scott Puzia Bottle cap medication timer
US9270025B2 (en) 2007-03-09 2016-02-23 Proteus Digital Health, Inc. In-body device having deployable antenna
US8261738B2 (en) * 2007-07-24 2012-09-11 Respironics Respiratory Drug Delivery (Uk) Ltd. Apparatus and method for maintaining consistency for aerosol drug delivery treatments
WO2009055733A1 (fr) 2007-10-25 2009-04-30 Proteus Biomedical, Inc. Système d'informations d'orifice de transfert de fluide
EP2058025B1 (fr) * 2007-11-09 2014-09-03 Hitachi Ltd. Appareil d'administration de médicament en poudre
WO2009067463A1 (fr) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Dispositifs d'évaluation de structures de transport de fluides associées au corps
ES2394589T3 (es) 2007-12-14 2013-02-04 Aerodesigns, Inc Suministro de productos alimenticios transformables en aerosol
US10004657B2 (en) 2008-02-08 2018-06-26 The University Of Western Ontario Method of brain activation
CN102099000B (zh) 2008-04-15 2015-07-22 特鲁德尔医学国际公司 吞咽空气脉冲疗法口器及其使用方法
US8082873B2 (en) 2008-05-05 2011-12-27 Trudell Medical International Drive mechanism for an indicating device
US8087548B2 (en) * 2008-05-14 2012-01-03 S.C. Johnson & Son, Inc. Spray products with particles and improved valve for inverted dispensing without clogging
US8181591B1 (en) 2008-05-23 2012-05-22 Trudell Medical International Domed actuator for indicating device
DK2570147T3 (da) 2008-06-13 2018-01-29 Mannkind Corp Tørpulverinhalator og system til lægemiddelindgivelse
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
US8517009B2 (en) 2008-07-13 2013-08-27 Map Pharmaceuticals, Inc. Methods and apparatus for delivering aerosolized medication
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8540633B2 (en) 2008-08-13 2013-09-24 Proteus Digital Health, Inc. Identifier circuits for generating unique identifiable indicators and techniques for producing same
AU2009286377A1 (en) * 2008-08-25 2010-03-04 Koninklijke Philips Electronics N.V. Respiratory drug delivery apparatus which provides audio instructions
CA2905402C (fr) 2008-10-22 2017-02-28 Trudell Medical International Systeme modulaire d'administration d'aerosol
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (fr) 2009-03-11 2017-06-27 Mannkind Corporation Appareil, systeme et procede de mesure de resistance d'un inhalateur
US8540664B2 (en) 2009-03-25 2013-09-24 Proteus Digital Health, Inc. Probablistic pharmacokinetic and pharmacodynamic modeling
WO2010129288A2 (fr) 2009-04-28 2010-11-11 Proteus Biomedical, Inc. Marqueurs d'évènement comestibles à haute fiabilité et leurs procédés d'utilisation
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (fr) 2009-11-03 2011-05-12 Mannkind Corporation Appareil et methode de simulation d'efforts d'inhalation
WO2011083377A1 (fr) * 2010-01-07 2011-07-14 Koninklijke Philips Electronics N.V. Appareil d'administration d'un médicament pour voies respiratoires comprenant un dispositif de rétroaction et d'observance
SG189763A1 (en) 2010-02-01 2013-05-31 Proteus Digital Health Inc Two-wrist data gathering system
MX2012008922A (es) 2010-02-01 2012-10-05 Proteus Digital Health Inc Sistema de recoleccion de datos.
US8517729B2 (en) 2010-03-04 2013-08-27 The University of Western Ontario and Trudell Medical International Oral mouthpiece and method for the use thereof
AU2011237612B2 (en) 2010-04-07 2016-05-12 Otsuka Pharmaceutical Co., Ltd. Miniature ingestible device
US20130172690A1 (en) * 2010-04-11 2013-07-04 Proteus Digital Health, Inc. Apparatus, system and method for detection and delivery of a medicinal dose
GB201006901D0 (en) 2010-04-26 2010-06-09 Sagentia Ltd Device for monitoring status and use of an inhalation or nasal drug delivery device
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
WO2012071280A2 (fr) 2010-11-22 2012-05-31 Proteus Biomedical, Inc. Dispositif ingérable avec produit pharmaceutique
US9555200B2 (en) 2011-03-15 2017-01-31 Novartis Ag Inhaler
DK2689359T3 (da) * 2011-03-24 2021-02-08 Sanofi Aventis Deutschland Apparat og fremgangsmåde til påvisning af en aktiveringshandling, der kan udføres med en medicinsk anordning
MY180552A (en) 2011-04-01 2020-12-02 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (fr) 2011-06-17 2012-12-20 Mannkind Corporation Microparticules de dicétopipérazine de capacité élevée
WO2015112603A1 (fr) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Produit ingérable pouvant être mâché et système de communication associé
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
WO2013016784A1 (fr) * 2011-08-04 2013-02-07 Victor Esteve Inhalateur de poudre sèche
WO2013036881A2 (fr) * 2011-09-07 2013-03-14 Syphase, Llc Dispositif d'inhalation de poudre sèche
WO2013063160A1 (fr) 2011-10-24 2013-05-02 Mannkind Corporation Procédés et compositions pour traiter la douleur
US10283014B2 (en) 2012-04-04 2019-05-07 Jbcb Holdings, Llc Smart packaging and display system
US9767708B2 (en) 2012-04-04 2017-09-19 Genia Medical Inc. Medicament training device and system
CA3176610A1 (fr) 2012-06-25 2014-01-03 Gecko Health Innovations, Inc. Dispositifs, systemes et procedes pour surveillance de l'adhesion et interaction de patient
CA2878457C (fr) 2012-07-12 2021-01-19 Mannkind Corporation Systemes et procedes de liberation de medicament en poudre seche
RU2015105699A (ru) 2012-07-23 2016-09-10 Протеус Диджитал Хелс, Инк. Способы получения проглатываемых маркеров событий, содержащих проглатываемый компонент
US10029056B2 (en) * 2012-08-29 2018-07-24 The Provost, Fellows, Foundation Scholars, & The Other Members Of Board, Of The College Of The Holy & Undivided Trinity Of Queen Elizabeth Near Dublin System and method for monitoring use of a device
JP5869736B2 (ja) 2012-10-18 2016-02-24 プロテウス デジタル ヘルス, インコーポレイテッド 通信デバイス用の電源において電力消失およびブロードキャスト電力を適応的に最適化するための装置、システム、および方法
GB2507104A (en) * 2012-10-19 2014-04-23 Nicoventures Holdings Ltd Electronic inhalation device
WO2014066856A1 (fr) 2012-10-26 2014-05-01 Mannkind Corporation Compositions et procédés de vaccin antigrippal inhalable
TWI659994B (zh) 2013-01-29 2019-05-21 美商普羅托斯數位健康公司 高度可膨脹之聚合型薄膜及包含彼之組成物
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
EP2967956A4 (fr) 2013-03-15 2017-03-22 Trudell Medical International Embout buccal oral et son procédé d'utilisation
JP5941240B2 (ja) 2013-03-15 2016-06-29 プロテウス デジタル ヘルス, インコーポレイテッド 金属検出器装置、システム、および方法
WO2014204511A2 (fr) 2013-06-18 2014-12-24 Isonea Limited Surveillance d'observance pour inhalateurs d'asthme
US20160166766A1 (en) * 2013-07-12 2016-06-16 Oscillari Llc Acoustic based drug delivery monitor
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
CA2920488C (fr) 2013-08-05 2022-04-26 Mannkind Corporation Appareil d'insufflation et procedes
EP3038687B1 (fr) 2013-08-28 2019-02-27 Gecko Health Innovations, Inc. Dispositifs pour un contrôle du respect de l'observance, et dispositifs pour surveiller l'utilisation de distributeurs de produits consommables
US10828434B2 (en) * 2013-08-30 2020-11-10 Adherium (Nz) Limited Compliance monitor for a medicament inhaler
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
US11424017B2 (en) 2013-10-19 2022-08-23 Aptargroup, Inc. Respiratory system and method that monitors medication flow
US10019555B2 (en) 2013-10-19 2018-07-10 Cohero Health, Inc. Interactive respiratory device usage tracking system
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
PL3789066T3 (pl) * 2014-03-03 2023-03-20 Adherium (Nz) Limited Monitor prawidłowości podawania leku do urządzenia dostarczającego suchy sproszkowany lek
RU2664624C2 (ru) * 2014-03-25 2018-08-21 Конинклейке Филипс Н.В. Ингалятор с двумя микрофонами для обнаружения вдыхаемого потока
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
SE538399C2 (sv) * 2014-04-03 2016-06-14 Iconovo Ab Torrpulverinhalator
SE538400C2 (sv) * 2014-04-03 2016-06-14 Iconovo Ab Torrpulverinhalator
SE539930C2 (sv) * 2014-04-03 2018-01-23 Iconovo Ab Torrpulverinhalator
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
KR20160098719A (ko) * 2015-02-11 2016-08-19 엘지전자 주식회사 약통을 위한 디지털 캡 및 모바일 디바이스의 제어 방법
EP3058970A1 (fr) 2015-02-19 2016-08-24 Sanofi-Aventis Deutschland GmbH Dispositif de collecte de données destiné à être fixé à un dispositif d'injection
ES2805230T5 (es) 2015-06-09 2023-11-24 Sanofi Aventis Deutschland Aparato de recopilación de datos para su fijación a un dispositivo de inyección
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
GB201517089D0 (en) 2015-09-28 2015-11-11 Nicoventures Holdings Ltd Vaping heat map system and method for electronic vapour provision systems
DE102015119617A1 (de) 2015-11-13 2017-05-18 Alfred Von Schuckmann Handbetätigbarer Inhalator
US10894142B2 (en) 2016-03-24 2021-01-19 Trudell Medical International Respiratory care system with electronic indicator
EP3442627B1 (fr) 2016-04-12 2021-09-01 Biocorp Production S.A. Dispositif additionnel d'aérosol-doseur
US10512921B2 (en) * 2016-05-09 2019-12-24 Funai Electric Co., Ltd. Maintenance apparatus for vaporizing device
CN109475711B (zh) 2016-05-19 2022-04-15 曼金德公司 用于检测和监控吸入的装置、系统和方法
CA3020577C (fr) 2016-05-19 2023-08-01 Trudell Medical International Chambre de retenue a valve intelligente
EP3984579A1 (fr) 2016-07-08 2022-04-20 Trudell Medical International Dispositif intelligent à pression expiratoire positive oscillante
BR112019000861B1 (pt) 2016-07-22 2020-10-27 Proteus Digital Health, Inc dispositivo eletrônico
CA3041041A1 (fr) 2016-10-26 2018-05-03 Proteus Digital Health, Inc. Procedes de preparation de capsules avec des marqueurs d'evenement ingerables
CA3036631A1 (fr) 2016-12-09 2018-06-14 Trudell Medical International Nebuliseur intelligent
US10989803B1 (en) 2017-08-21 2021-04-27 Massachusetts Institute Of Technology Security protocol for motion tracking systems
US11666801B2 (en) 2018-01-04 2023-06-06 Trudell Medical International Smart oscillating positive expiratory pressure device
BR112020016528A2 (pt) * 2018-03-26 2020-12-15 Philip Morris Products S.A. Inalador com elemento de suporte poroso com abertura
US11071836B2 (en) 2018-03-29 2021-07-27 Reciprocal Labs Corporation Single dose inhaler monitoring attachment
WO2019215471A1 (fr) 2018-05-11 2019-11-14 Biocorp Production S.A. Inhalateur doseur portatif
US11395890B2 (en) 2018-06-04 2022-07-26 Trudell Medical International Smart valved holding chamber
JP2022547826A (ja) 2019-08-27 2022-11-16 トゥルーデル メディカル インターナショナル 振動型呼気陽圧器具

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
IT941426B (it) * 1971-07-17 1973-03-01 Isf Spa Inalatore a camera di turbinio per sostanze medicamentose polveriformi
US4109656A (en) * 1977-02-07 1978-08-29 Sybron Corporation Apparatus for use with insufflators
IL58720A (en) * 1979-01-11 1984-02-29 Scherico Ltd Inhalation device
GB2063075B (en) * 1979-11-07 1983-11-09 Sterwin Ag Dose indicator for inhalers
US4484577A (en) * 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
NZ209900A (en) * 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
FI88112C (fi) * 1985-07-30 1993-04-13 Glaxo Group Ltd Anordning foer administrering av laekemedel till patienter
GB2191032B (en) * 1986-04-25 1990-05-16 Glaxo Group Ltd Indicating device
US4830022A (en) * 1987-07-27 1989-05-16 Medical Engineering And Development, Inc. Animal monitoring system
US4984158A (en) * 1988-10-14 1991-01-08 Hillsman Dean Metered dose inhaler biofeedback training and evaluation system
US5020527A (en) * 1990-02-20 1991-06-04 Texax-Glynn Corporation Inhaler device with counter/timer means
US5042467A (en) * 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device

Also Published As

Publication number Publication date
DK0387222T3 (da) 1993-08-30
AU613264B2 (en) 1991-07-25
WO1990010470A1 (fr) 1990-09-20
IE900765L (en) 1990-09-07
ES2042267T3 (es) 1993-12-01
EP0387222A1 (fr) 1990-09-12
JP2927541B2 (ja) 1999-07-28
SE8900793L (sv) 1990-09-08
PT93347B (pt) 1998-05-29
SE8900793D0 (sv) 1989-03-07
NO904809L (no) 1990-11-05
NO175289C (no) 1994-09-28
KR0135309B1 (ko) 1998-04-23
NO904809D0 (no) 1990-11-05
NO175289B (no) 1994-06-20
US5331953A (en) 1994-07-26
DE69002353D1 (de) 1993-09-02
KR920700050A (ko) 1992-02-19
DE69002353T2 (de) 1993-12-02
EP0387222B1 (fr) 1993-07-28
JPH03504457A (ja) 1991-10-03
SE466684B (sv) 1992-03-23
ATE91911T1 (de) 1993-08-15
CA2028830C (fr) 2000-02-08
IE64129B1 (en) 1995-07-12
AU5271090A (en) 1990-10-09
FI905521A0 (fi) 1990-11-07
FI102948B (fi) 1999-03-31
PT93347A (pt) 1990-11-07
FI102948B1 (fi) 1999-03-31

Similar Documents

Publication Publication Date Title
CA2028830A1 (fr) Dispositif relie a un inhalateur
EP0220860A3 (fr) Ruban de mesure destiné à la détermination immédiate de grandeurs physiologiques et de paramètres de traitement physique
WO2004067083A3 (fr) Systeme de defibrillation destine a des milieux non medicaux
Crosby et al. A small-dose iron tolerance test as an indicator of mild iron deficiency
HORST et al. COGSCREEN- Personal computer-based tests of cognitive function for occupational medical certification
Larsson et al. Breath‐by‐breath determination of inspiratory occlusion pressure
Chowienczyk et al. Electronic diary to record physiological measurements
Svendsen et al. Comparison of two aerosols containing both fenoterol and ipratropium in a high (Duovent®) and low (Berodual®) concentration, respectively
McHenry Jr et al. Comparison of the effects of intravenous papaverine hydrochloride and oral pavabid HP capsulets on regional cerebral blood flow in normal individuals
Wedding et al. Training options in behavioral medicine and clinical neuropsychology.
Elufimova et al. Side effects of antituberculous drugs and their diagnosis with the Shelley test in children.
Strimlan et al. Correct height measurement for pulmonary function testing parameters
Ulett Food allergy: Cytotoxic testing and the central nervous system.
Hendley et al. Antitussive Effect of Guaifenesin
Wassner Patient Care for Safety.
Bloodworth Detection of drug abuse presenting as psychiatric illness.
Falliers Antitussive Effect of Guaifenesin
Gualtieri The problem of tardive dyskinesia litigation.
Bassetti et al. Rifampicin's Tolerance in Paediatrics.
WO2003010557A1 (fr) Radiametre
Robinson The testicular scan: use in diagnosis and management of acute epididymitis: Vordermark JS, Buck AS, Brown SR, et al JAMA 245: 2512–2514 June 1981
Mitchiner Blood carboxyhaemoglobin and cyanide levels in fire survivors: Clark CJ, Campbell D, Reid WH Lancet 1: 1332–1335 Jun 1981
Strambi Accidental Radiation Injuries: Whole-Body Radiation Syndromes
Larremore The effects of nitroglycerin on cerebrospinal fluid pressure in awake and anesthetized humans: Shuji D, Matsumoto M, Takahashi T Anesthesiology 54: 511–514 Jun 1981
Cohen Utilization of the Fateful Forty-Three in New Jersey.

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry