CA1336905C - Pyrido [3,2,1,ij]-1,3,4-benzoxadiazine derivatives - Google Patents

Pyrido [3,2,1,ij]-1,3,4-benzoxadiazine derivatives

Info

Publication number
CA1336905C
CA1336905C CA000546674A CA546674A CA1336905C CA 1336905 C CA1336905 C CA 1336905C CA 000546674 A CA000546674 A CA 000546674A CA 546674 A CA546674 A CA 546674A CA 1336905 C CA1336905 C CA 1336905C
Authority
CA
Canada
Prior art keywords
methyl
oxo
fluoro
dihydro
pyrido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000546674A
Other languages
English (en)
French (fr)
Inventor
Masahiro Aoki
Miyako Kamata
Tatsuo Ohtsuka
Nobuo Shimma
Kazuteru Yokose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1336905C publication Critical patent/CA1336905C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA000546674A 1986-09-12 1987-09-11 Pyrido [3,2,1,ij]-1,3,4-benzoxadiazine derivatives Expired - Lifetime CA1336905C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP86112619 1986-09-12
EP86112619.1 1986-09-12

Publications (1)

Publication Number Publication Date
CA1336905C true CA1336905C (en) 1995-09-05

Family

ID=8195410

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000546674A Expired - Lifetime CA1336905C (en) 1986-09-12 1987-09-11 Pyrido [3,2,1,ij]-1,3,4-benzoxadiazine derivatives

Country Status (22)

Country Link
JP (3) JPH0696578B2 (es)
KR (1) KR960002857B1 (es)
CN (1) CN1017800B (es)
AT (1) AT389119B (es)
AU (1) AU602534B2 (es)
CA (1) CA1336905C (es)
CZ (1) CZ281195B6 (es)
DK (1) DK173330B1 (es)
DZ (1) DZ1124A1 (es)
FI (1) FI86428C (es)
HU (1) HU199481B (es)
IE (1) IE61624B1 (es)
IL (1) IL83814A (es)
MC (1) MC1850A1 (es)
MX (1) MX8302A (es)
NO (1) NO169125C (es)
NZ (1) NZ221681A (es)
PH (1) PH23930A (es)
PT (1) PT85686B (es)
SK (1) SK278990B6 (es)
ZA (1) ZA876636B (es)
ZW (1) ZW16387A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006248354B2 (en) * 2005-05-19 2011-11-03 Daiichi Sankyo Company, Limited Tri- or tetra-substituted-3-aminopyrrolidine derivatives

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW16387A1 (en) * 1986-09-12 1988-05-25 Hoffmann La Roche Tricyclic compounds
EP1757598A4 (en) 2004-05-13 2010-07-21 Daiichi Seiyaku Co SUBSTITUTED PYRROLIDINE DERIVATIVE
CN101443314B (zh) 2006-03-13 2014-04-09 杏林制药株式会社 作为gsk-3抑制剂的氨基喹诺酮类
JP5426552B2 (ja) 2007-09-11 2014-02-26 杏林製薬株式会社 Ｇｓｋ−３阻害剤としてのシアノアミノキノロン及びテトラゾロアミノキノロン
MX2010002662A (es) 2007-09-12 2010-04-09 Activx Biosciences Inc Aminoquinolonas espirociclicas como inhibidores de gsk-3.
FR2928150A1 (fr) * 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
EP2145891A1 (en) * 2008-07-09 2010-01-20 Vetoquinol S.A. 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
WO2010104205A1 (en) 2009-03-11 2010-09-16 Kyorin Pharmaceutical Co., Ltd. 7-cycloalkylaminoquinolones as gsk-3 inhibitors
CN107522718B (zh) * 2017-09-14 2019-11-08 浙江国邦药业有限公司 一种马波沙星的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW16387A1 (en) * 1986-09-12 1988-05-25 Hoffmann La Roche Tricyclic compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006248354B2 (en) * 2005-05-19 2011-11-03 Daiichi Sankyo Company, Limited Tri- or tetra-substituted-3-aminopyrrolidine derivatives

Also Published As

Publication number Publication date
KR960002857B1 (ko) 1996-02-27
ATA263887A (de) 1989-03-15
SK660487A3 (en) 1998-05-06
DK173330B1 (da) 2000-07-24
NO169125B (no) 1992-02-03
FI86428C (fi) 1992-08-25
MC1850A1 (fr) 1988-09-30
IL83814A (en) 1991-09-16
IE872444L (en) 1988-03-12
CN87106838A (zh) 1988-05-11
HUT47294A (en) 1989-02-28
DK477287A (da) 1988-03-13
JPH07138262A (ja) 1995-05-30
FI86428B (fi) 1992-05-15
JPH0826030B2 (ja) 1996-03-13
NO873816L (no) 1988-03-14
PT85686B (pt) 1990-05-31
KR880003954A (ko) 1988-06-01
NO873816D0 (no) 1987-09-11
HU199481B (en) 1990-02-28
SK278990B6 (sk) 1998-05-06
JPS63132891A (ja) 1988-06-04
AU602534B2 (en) 1990-10-18
CN1017800B (zh) 1992-08-12
AU7811487A (en) 1988-03-17
ZA876636B (en) 1988-07-27
CZ660487A3 (en) 1996-04-17
IE61624B1 (en) 1994-11-16
JPH07138256A (ja) 1995-05-30
ZW16387A1 (en) 1988-05-25
DK477287D0 (da) 1987-09-11
FI873940A (fi) 1988-03-13
CZ281195B6 (cs) 1996-07-17
PH23930A (en) 1990-01-23
JPH0819120B2 (ja) 1996-02-28
PT85686A (en) 1987-10-01
NO169125C (no) 1992-05-13
AT389119B (de) 1989-10-25
FI873940A0 (fi) 1987-09-11
JPH0696578B2 (ja) 1994-11-30
NZ221681A (en) 1990-12-21
DZ1124A1 (fr) 2004-09-13
MX8302A (es) 1993-12-01

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