CA1305058C - Parenteral suspension containing diclofenac - Google Patents

Parenteral suspension containing diclofenac

Info

Publication number
CA1305058C
CA1305058C CA000557536A CA557536A CA1305058C CA 1305058 C CA1305058 C CA 1305058C CA 000557536 A CA000557536 A CA 000557536A CA 557536 A CA557536 A CA 557536A CA 1305058 C CA1305058 C CA 1305058C
Authority
CA
Canada
Prior art keywords
diclofenac
salt
dry formulation
preparation
micronised
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000557536A
Other languages
English (en)
French (fr)
Inventor
Leo Geller
Peter Glanzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of CA1305058C publication Critical patent/CA1305058C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
CA000557536A 1987-01-30 1988-01-28 Parenteral suspension containing diclofenac Expired - Lifetime CA1305058C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH350/87A CH673395A5 (ko) 1987-01-30 1987-01-30
CH350/87-4 1987-01-30

Publications (1)

Publication Number Publication Date
CA1305058C true CA1305058C (en) 1992-07-14

Family

ID=4185019

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000557536A Expired - Lifetime CA1305058C (en) 1987-01-30 1988-01-28 Parenteral suspension containing diclofenac

Country Status (26)

Country Link
JP (1) JPS63192716A (ko)
KR (1) KR880008808A (ko)
AT (1) AT397460B (ko)
AU (1) AU612343B2 (ko)
BE (1) BE1000442A4 (ko)
CA (1) CA1305058C (ko)
CH (1) CH673395A5 (ko)
DE (1) DE3802357A1 (ko)
DK (1) DK45588A (ko)
ES (1) ES2008420A6 (ko)
FI (1) FI880368A (ko)
FR (1) FR2611498B1 (ko)
GB (1) GB2201089B (ko)
GR (1) GR880100041A (ko)
IE (1) IE60453B1 (ko)
IT (1) IT1224241B (ko)
LU (1) LU87115A1 (ko)
MY (1) MY102662A (ko)
NL (1) NL8800231A (ko)
NO (1) NO880403L (ko)
NZ (1) NZ223343A (ko)
PH (1) PH23652A (ko)
PT (1) PT86644B (ko)
SE (1) SE8800228L (ko)
YU (1) YU15488A (ko)
ZA (1) ZA88638B (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH675537A5 (ko) * 1988-03-25 1990-10-15 Ciba Geigy Ag
MX9201782A (es) * 1991-04-19 1992-10-01 Sandoz Ag Particulas de sustancias biologicamente activas, sustancialmente insolubles en agua, proceso para su produccion y composicion farmaceutica que las contiene.
DE4140185C2 (de) * 1991-12-05 1996-02-01 Alfatec Pharma Gmbh Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140183C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Flurbiprofen enthaltendes Arzneimittel
GB9212450D0 (en) * 1992-06-11 1992-07-22 Indena Spa New derivatives of non-steroidal anti-inflammatory,analgesic and/or antipyretic substances,their use and pharmaceutical formulations containing them
ZA949182B (en) * 1993-12-02 1995-07-26 South African Druggists Ltd Pharmaceutical composition
US6447806B1 (en) 1999-02-25 2002-09-10 Novartis Ag Pharmaceutical compositions comprised of stabilized peptide particles
FR2793418B1 (fr) * 1999-05-11 2001-07-27 Synthelabo Formulations galeniques d'agents antithrombotiques pour administration sous-cutanee
GB0207529D0 (en) * 2002-04-02 2002-05-08 Norbrook Lab Ltd Injectable veterinary composition for small animals
JO3352B1 (ar) * 2005-06-17 2019-03-13 Apr Applied Pharma Res Sa صيغ دايكلوفيناك وطرق استخدامه

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1373913A (en) * 1970-12-17 1974-11-13 Glaxo Lab Ltd Pharmaceutical compositions
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
DE3324193A1 (de) * 1983-07-05 1985-01-17 Troponwerke Gmbh & Co Kg Depot-antiphlogistika
DE3328401A1 (de) * 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren Injizierbare loesung zur behandlung von entzuendungen
EP0152379A3 (de) * 1984-02-15 1986-10-29 Ciba-Geigy Ag Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5002940A (en) * 1984-11-06 1991-03-26 Ciba-Geigy Corporation Solid drug formulations and stable suspensions
DE3446873A1 (de) * 1984-12-21 1986-07-10 Merckle Gmbh Fluessige diclofenac-zubereitungen
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
DE3607339A1 (de) * 1986-03-06 1987-09-10 Merck Patent Gmbh Pharmazeutische zubereitung

Also Published As

Publication number Publication date
IE60453B1 (en) 1994-07-13
PT86644B (pt) 1992-01-31
LU87115A1 (fr) 1989-03-08
DE3802357A1 (de) 1988-08-11
DK45588A (da) 1988-07-31
ES2008420A6 (es) 1989-07-16
PH23652A (en) 1989-09-27
SE8800228L (sv) 1988-07-31
NZ223343A (en) 1990-03-27
FR2611498A1 (fr) 1988-09-09
MY102662A (en) 1992-08-17
NL8800231A (nl) 1988-08-16
KR880008808A (ko) 1988-09-13
GB2201089A (en) 1988-08-24
PT86644A (pt) 1988-02-01
CH673395A5 (ko) 1990-03-15
IT8847557A0 (it) 1988-08-21
GB8801737D0 (en) 1988-02-24
AU612343B2 (en) 1991-07-11
JPS63192716A (ja) 1988-08-10
NO880403L (no) 1988-08-01
FI880368A (fi) 1988-07-31
GB2201089B (en) 1990-05-16
YU15488A (en) 1989-10-31
AU1110288A (en) 1988-08-04
NO880403D0 (no) 1988-01-29
ZA88638B (en) 1989-10-25
GR880100041A (el) 1988-12-16
IE880250L (en) 1988-07-30
FI880368A0 (fi) 1988-01-27
BE1000442A4 (fr) 1988-12-06
DK45588D0 (da) 1988-01-29
IT1224241B (it) 1990-09-26
ATA18588A (de) 1993-09-15
SE8800228D0 (sv) 1988-01-25
FR2611498B1 (fr) 1991-06-14
AT397460B (de) 1994-04-25

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