CA1300141C - Piperazine derivatives and process for the preparation thereof - Google Patents

Piperazine derivatives and process for the preparation thereof

Info

Publication number
CA1300141C
CA1300141C CA000559846A CA559846A CA1300141C CA 1300141 C CA1300141 C CA 1300141C CA 000559846 A CA000559846 A CA 000559846A CA 559846 A CA559846 A CA 559846A CA 1300141 C CA1300141 C CA 1300141C
Authority
CA
Canada
Prior art keywords
compound
formula
process according
general formula
stands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000559846A
Other languages
English (en)
French (fr)
Inventor
Zoltan Budai
Livia Nee Boros Gregor
Tibor Mezei
Eva J. Nee Juhasz Tajthy
Klara Nee Esses Reiter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egis Pharmaceuticals PLC
Original Assignee
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU71787A external-priority patent/HU198204B/hu
Priority claimed from HU71887A external-priority patent/HU198477B/hu
Priority claimed from HU71687A external-priority patent/HU197313B/hu
Application filed by Egis Pharmaceuticals PLC filed Critical Egis Pharmaceuticals PLC
Application granted granted Critical
Publication of CA1300141C publication Critical patent/CA1300141C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA000559846A 1987-02-25 1988-02-25 Piperazine derivatives and process for the preparation thereof Expired - Lifetime CA1300141C (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
HU71787A HU198204B (en) 1987-02-25 1987-02-25 Process for production of derivatives of piperasine
HU717/87 1987-02-25
HU71887A HU198477B (en) 1987-02-25 1987-02-25 Process for producing pyrimidinyl piperazine derivatives
HU716/87 1987-02-25
HU71687A HU197313B (en) 1987-02-25 1987-02-25 Process for producing 8-azaspiro <4.5> decane-7,9-dione-8-propine-/2/
HU718/87 1987-02-25

Publications (1)

Publication Number Publication Date
CA1300141C true CA1300141C (en) 1992-05-05

Family

ID=27269942

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000559846A Expired - Lifetime CA1300141C (en) 1987-02-25 1988-02-25 Piperazine derivatives and process for the preparation thereof

Country Status (20)

Country Link
KR (1) KR880009955A (zh)
CN (1) CN88100923A (zh)
AT (1) AT395851B (zh)
BE (1) BE1001464A3 (zh)
CA (1) CA1300141C (zh)
CH (1) CH677924A5 (zh)
CS (1) CS274423B2 (zh)
DE (1) DE3806009C2 (zh)
DK (1) DK99388A (zh)
ES (1) ES2009236A6 (zh)
FI (1) FI880895A (zh)
FR (1) FR2615853B1 (zh)
GB (1) GB2201417B (zh)
GR (1) GR1002245B (zh)
IL (1) IL85545A (zh)
IT (1) IT1217342B (zh)
NL (1) NL8800484A (zh)
PL (1) PL152958B1 (zh)
SE (1) SE8800651L (zh)
YU (1) YU46441B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU217129B (hu) * 1993-07-16 1999-11-29 EGIS Gyógyszergyár Rt. Eljárás nagy tisztaságú buspiron gyógyászati hatóanyag előállítására
KR950014099A (ko) * 1993-11-10 1995-06-15 장기하 N-(2-피리미딜)피페라지닐 부틸아미드의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE300422B (zh) * 1964-07-03 1968-04-29 Astra Ab
DE1545543B1 (de) * 1964-07-03 1970-01-22 Astra Apotekarnes Kem Fab 4-Aminobutinylimide,ihre Salze und Verfahren zu deren Herstellung
US3354178A (en) * 1965-04-09 1967-11-21 Sterling Drug Inc Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
JPS6310786A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd 新規イミド誘導体およびその製造法
JPS6310760A (ja) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd イミド誘導体の新規製造法

Also Published As

Publication number Publication date
SE8800651D0 (sv) 1988-02-25
FI880895A (fi) 1988-08-26
IL85545A0 (en) 1988-08-31
GR1002245B (en) 1996-04-22
FR2615853B1 (fr) 1991-01-04
CH677924A5 (zh) 1991-07-15
CN88100923A (zh) 1988-09-28
IL85545A (en) 1992-05-25
CS122288A2 (en) 1990-08-14
DE3806009C2 (de) 1996-09-12
ATA47688A (de) 1992-08-15
DK99388A (da) 1988-08-26
BE1001464A3 (fr) 1989-11-07
GB8804385D0 (en) 1988-03-23
AT395851B (de) 1993-03-25
YU36288A (en) 1989-10-31
DK99388D0 (da) 1988-02-25
NL8800484A (nl) 1988-09-16
PL270815A1 (en) 1989-04-03
FR2615853A1 (fr) 1988-12-02
ES2009236A6 (es) 1989-09-16
GB2201417B (en) 1990-10-31
YU46441B (sh) 1993-10-20
GR880100108A (el) 1988-12-16
FI880895A0 (fi) 1988-02-25
KR880009955A (ko) 1988-10-06
GB2201417A (en) 1988-09-01
PL152958B1 (en) 1991-02-28
IT1217342B (it) 1990-03-22
IT8819545A0 (it) 1988-02-25
SE8800651L (sv) 1988-08-26
CS274423B2 (en) 1991-04-11
DE3806009A1 (de) 1988-09-08

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