CS122288A2 - Method of 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl) butyl)-8-aza-spiro (4,5)-decane-7,9-dione preparation - Google Patents

Method of 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl) butyl)-8-aza-spiro (4,5)-decane-7,9-dione preparation

Info

Publication number
CS122288A2
CS122288A2 CS881222A CS122288A CS122288A2 CS 122288 A2 CS122288 A2 CS 122288A2 CS 881222 A CS881222 A CS 881222A CS 122288 A CS122288 A CS 122288A CS 122288 A2 CS122288 A2 CS 122288A2
Authority
CS
Czechoslovakia
Prior art keywords
aza
decane
piperazinyl
spiro
pyrimidinyl
Prior art date
Application number
CS881222A
Other languages
Czech (cs)
Other versions
CS274423B2 (en
Inventor
Zoltan Dr Budai
Livia Gregor
Tibor Dr Mezei
Klara Dr Reiter
Eva J Tajthy
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU71787A external-priority patent/HU198204B/en
Priority claimed from HU71687A external-priority patent/HU197313B/en
Priority claimed from HU71887A external-priority patent/HU198477B/en
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of CS122288A2 publication Critical patent/CS122288A2/en
Publication of CS274423B2 publication Critical patent/CS274423B2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS122288A 1987-02-25 1988-02-25 Method of 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl) butyl)-8-aza-spiro (4,5)-decane-7,9-dione preparation CS274423B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU71787A HU198204B (en) 1987-02-25 1987-02-25 Process for production of derivatives of piperasine
HU71687A HU197313B (en) 1987-02-25 1987-02-25 Process for producing 8-azaspiro <4.5> decane-7,9-dione-8-propine-/2/
HU71887A HU198477B (en) 1987-02-25 1987-02-25 Process for producing pyrimidinyl piperazine derivatives

Publications (2)

Publication Number Publication Date
CS122288A2 true CS122288A2 (en) 1990-08-14
CS274423B2 CS274423B2 (en) 1991-04-11

Family

ID=27269942

Family Applications (1)

Application Number Title Priority Date Filing Date
CS122288A CS274423B2 (en) 1987-02-25 1988-02-25 Method of 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl) butyl)-8-aza-spiro (4,5)-decane-7,9-dione preparation

Country Status (20)

Country Link
KR (1) KR880009955A (en)
CN (1) CN88100923A (en)
AT (1) AT395851B (en)
BE (1) BE1001464A3 (en)
CA (1) CA1300141C (en)
CH (1) CH677924A5 (en)
CS (1) CS274423B2 (en)
DE (1) DE3806009C2 (en)
DK (1) DK99388A (en)
ES (1) ES2009236A6 (en)
FI (1) FI880895A (en)
FR (1) FR2615853B1 (en)
GB (1) GB2201417B (en)
GR (1) GR1002245B (en)
IL (1) IL85545A (en)
IT (1) IT1217342B (en)
NL (1) NL8800484A (en)
PL (1) PL152958B1 (en)
SE (1) SE8800651L (en)
YU (1) YU46441B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU217129B (en) * 1993-07-16 1999-11-29 EGIS Gyógyszergyár Rt. Process for the preparation of buspiron as therapeutical active ingredient of high purity
KR950014099A (en) * 1993-11-10 1995-06-15 장기하 Method for preparing N- (2-pyrimidyl) piperazinyl butylamide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545543B1 (en) * 1964-07-03 1970-01-22 Astra Apotekarnes Kem Fab 4-aminobutinylimides, their salts and processes for their preparation
SE300422B (en) * 1964-07-03 1968-04-29 Astra Ab
US3354178A (en) * 1965-04-09 1967-11-21 Sterling Drug Inc Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides
BE759371A (en) * 1969-11-24 1971-05-24 Bristol Myers Co HETEROCYCLICAL AZASPIRODECANEDIONES AND METHODS FOR THEIR PREPARATION
JPS6310786A (en) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd Novel imide derivative and production thereof
JPS6310760A (en) * 1986-07-01 1988-01-18 Sumitomo Pharmaceut Co Ltd Novel production of imide derivative

Also Published As

Publication number Publication date
DK99388D0 (en) 1988-02-25
YU36288A (en) 1989-10-31
GR880100108A (en) 1988-12-16
CN88100923A (en) 1988-09-28
DE3806009A1 (en) 1988-09-08
BE1001464A3 (en) 1989-11-07
PL270815A1 (en) 1989-04-03
GB8804385D0 (en) 1988-03-23
ATA47688A (en) 1992-08-15
IL85545A (en) 1992-05-25
DE3806009C2 (en) 1996-09-12
FR2615853A1 (en) 1988-12-02
IT8819545A0 (en) 1988-02-25
YU46441B (en) 1993-10-20
AT395851B (en) 1993-03-25
KR880009955A (en) 1988-10-06
GR1002245B (en) 1996-04-22
FI880895A0 (en) 1988-02-25
SE8800651D0 (en) 1988-02-25
NL8800484A (en) 1988-09-16
FI880895A (en) 1988-08-26
GB2201417A (en) 1988-09-01
PL152958B1 (en) 1991-02-28
CA1300141C (en) 1992-05-05
ES2009236A6 (en) 1989-09-16
SE8800651L (en) 1988-08-26
IL85545A0 (en) 1988-08-31
DK99388A (en) 1988-08-26
GB2201417B (en) 1990-10-31
IT1217342B (en) 1990-03-22
CH677924A5 (en) 1991-07-15
FR2615853B1 (en) 1991-01-04
CS274423B2 (en) 1991-04-11

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