CA1211059A - RECOMBINANT PLASMID CONTAINING HUMAN INTERFERON-.beta. GENE - Google Patents

RECOMBINANT PLASMID CONTAINING HUMAN INTERFERON-.beta. GENE

Info

Publication number
CA1211059A
CA1211059A CA000418366A CA418366A CA1211059A CA 1211059 A CA1211059 A CA 1211059A CA 000418366 A CA000418366 A CA 000418366A CA 418366 A CA418366 A CA 418366A CA 1211059 A CA1211059 A CA 1211059A
Authority
CA
Canada
Prior art keywords
dna
beta
plasm
human interferon
promoter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000418366A
Other languages
English (en)
French (fr)
Inventor
Seiga Itoh
Tatsunari Nishi
Tamio Mizukami
Tadashi Matsumoto
Tetsuo Oka
Tadatsugu Taniguchi
Haruo Sugano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japanese Foundation for Cancer Research
KH Neochem Co Ltd
Original Assignee
Japanese Foundation for Cancer Research
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japanese Foundation for Cancer Research, Kyowa Hakko Kogyo Co Ltd filed Critical Japanese Foundation for Cancer Research
Application granted granted Critical
Publication of CA1211059A publication Critical patent/CA1211059A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/142—Interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
CA000418366A 1981-12-25 1982-12-22 RECOMBINANT PLASMID CONTAINING HUMAN INTERFERON-.beta. GENE Expired CA1211059A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP213193/81 1981-12-25
JP56213193A JPS58110600A (ja) 1981-12-25 1981-12-25 ヒトβ型インタ−フエロン遺伝子を含む組みかえ体プラスミド

Publications (1)

Publication Number Publication Date
CA1211059A true CA1211059A (en) 1986-09-09

Family

ID=16635072

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000418366A Expired CA1211059A (en) 1981-12-25 1982-12-22 RECOMBINANT PLASMID CONTAINING HUMAN INTERFERON-.beta. GENE

Country Status (5)

Country Link
US (1) US4686191A (enExample)
EP (1) EP0083069B1 (enExample)
JP (1) JPS58110600A (enExample)
CA (1) CA1211059A (enExample)
DE (1) DE3277307D1 (enExample)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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JPS60188077A (ja) * 1984-03-09 1985-09-25 Teruhiko Beppu 仔牛プロキモシンｃＤΝＡの全配列を有する新規な発現プラスミド
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NO176799C (no) 1986-12-23 1995-05-31 Kyowa Hakko Kogyo Kk DNA som koder for et polypeptid, rekombinant plasmid som koder for og kan uttrykke et polypeptid og fremgangsmåte for fremstilling av dette polypeptid
DE4128319A1 (de) * 1991-08-27 1993-03-04 Bioferon Biochem Substanz Neues rekombinantes human-ifn-beta, verfahren zu dessen herstellung und dieses enthaltende pharmazeutische zubereitungen
US5723125A (en) * 1995-12-28 1998-03-03 Tanox Biosystems, Inc. Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
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EP1085090B1 (en) 1998-06-02 2011-12-14 Nihon University IgA NEPHROPATHY-ASSOCIATED DNA
US7431921B2 (en) * 1999-08-27 2008-10-07 Maxygen Aps Interferon beta-like molecules
US7144574B2 (en) 1999-08-27 2006-12-05 Maxygen Aps Interferon β variants and conjugates
US6531122B1 (en) * 1999-08-27 2003-03-11 Maxygen Aps Interferon-β variants and conjugates
EP1295939A4 (en) 2000-06-15 2005-02-02 Kyowa Hakko Kogyo Kk INSULIN SIMILAR GROWTH FACTOR BINDING PROTEIN
FR2810674A1 (fr) * 2000-06-22 2001-12-28 Pf Medicament Construction modifiee en amont du codon d'initiation pour la surexpression de proteines recombinantes
US20020169290A1 (en) * 2000-11-02 2002-11-14 Claus Bornaes New multimeric interferon beta polypeptides
JP3765574B2 (ja) * 2001-02-22 2006-04-12 三菱化学株式会社 逆向き反復配列を含む組み換え遺伝子及びその利用
EP1366075B1 (en) 2001-02-27 2009-05-27 Maxygen Aps New interferon beta-like molecules
US20040117868A1 (en) * 2002-01-29 2004-06-17 Jun Imamura Protein participating in restoration from cytoplasmic male sterility to fertility and gene encoding the same
AU2002251533B2 (en) 2001-04-25 2006-09-28 Institut National De La Recherche Agronomique Protein involved in restoration of cytoplasmic male sterility to fertility and gene encoding the protein and gene
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WO2003027296A1 (en) * 2001-09-20 2003-04-03 Plantech Research Institute GENES PARTICIPATING IN THE SYNTHESIS OF FATTY ACID HAVING trans-11-, cis-13- CONDJUGATED DOUBLE BOND AND UTILIZATION THEREOF
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ES2329566T3 (es) 2002-05-08 2009-11-27 Kyowa Hakko Bio Co., Ltd Procedimiento para la produccion de citidina 5'-difosfato colina.
JP4171256B2 (ja) * 2002-07-18 2008-10-22 三菱化学株式会社 パピローマウイルスベクターを用いたＲＮＡｉ表現型を有する非ヒト哺乳動物の作製方法
EP1923464A1 (en) 2002-08-30 2008-05-21 Japan Science and Technology Agency Ligase of a hyperthermostable bacterium and chip using the same
JP2004180641A (ja) * 2002-12-06 2004-07-02 Gencom Co ＲＮＡｉ表現型を有する非ヒト哺乳動物の作製方法
WO2004058960A1 (ja) 2002-12-26 2004-07-15 Kyowa Hakko Kogyo Co., Ltd. ジペプチドの製造法
WO2004078965A1 (ja) * 2003-03-05 2004-09-16 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 大腸菌における異種蛋白質の製造方法
BRPI0507169A (pt) 2004-02-02 2007-06-26 Ambrx Inc polipeptìdeos do hormÈnio de crescimento humano modificados e seu usos
UY29544A1 (es) * 2005-05-19 2006-12-29 Schering Ag Tratamiento de enfermedades usando un sistema mejorado de expresión regulada
US20070179113A1 (en) * 2005-05-19 2007-08-02 Schering Aktiengesellachaft GM-CSF gene therapy for Crohn's disease using an improved regulated expression system
DOP2006000117A (es) * 2005-05-19 2007-11-30 Schering Ag Terapia génica de interferon-beta usando un sistema mejorado de expresión regulada
US20080076729A1 (en) * 2005-05-19 2008-03-27 Schering Aktiengesellachaft Interferon-beta gene therapy using an improved, regulated expression system
EP1930344A4 (en) 2005-09-29 2008-12-31 Shionogi & Co POLYPEPTIDE HAVING ANTI-ANGIOGENIC ACTIVITY
JP5631534B2 (ja) 2005-11-29 2014-11-26 協和発酵バイオ株式会社 新規蛋白質および該蛋白質をコードするｄｎａ
WO2007066698A1 (ja) 2005-12-06 2007-06-14 Kyowa Hakko Kogyo Co., Ltd. 抗ｐｅｒｐ遺伝子組換え抗体
ES2382207T3 (es) 2005-12-27 2012-06-06 Kyowa Hakko Bio Co., Ltd. Procedimiento para la producción de L-glutamina
KR20090029227A (ko) 2006-06-06 2009-03-20 교와 핫꼬 기린 가부시키가이샤 헤파린 결합 상피세포 증식 인자 유사 증식 인자에 결합하는 모노클로날 항체
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US20100075343A1 (en) 2007-01-25 2010-03-25 Motoo Yamasaki Novel peptides
WO2008114733A1 (ja) 2007-03-16 2008-09-25 Kyowa Hakko Kirin Co., Ltd. 抗Claudin-4抗体
US20100113354A1 (en) 2007-03-29 2010-05-06 Yasufumi Sato Therapeutic agent comprising vasohibin
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WO2008126784A1 (ja) 2007-04-06 2008-10-23 Kyowa Hakko Bio Co., Ltd. グルタチオンおよびγ-グルタミルシステインの製造法
CN101675071B (zh) * 2007-05-02 2014-06-18 Ambrx公司 经修饰干扰素β多肽和其用途
JP5550041B2 (ja) 2007-09-27 2014-07-16 塩野義製薬株式会社 チトクロームｐ４５０を用いたアダマンタン水酸化体の製造方法
CA2707689A1 (en) 2007-12-05 2009-06-11 Kyowa Hakko Kirin Co., Ltd. Monoclonal antibody capable of binding to heparin-binding epidermal growth factor-like growth factor
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US8268592B2 (en) 2008-07-17 2012-09-18 Kyowa Hakko Kirin Co., Ltd Anti-system ASC amino acid transporter 2 (ASCT2) antibody
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ES2602459T3 (es) 2008-12-26 2017-02-21 Kyowa Hakko Kirin Co., Ltd. Anticuerpo anti-CD4
WO2010090330A1 (ja) 2009-02-09 2010-08-12 協和発酵バイオ株式会社 Ｌ－アミノ酸の製造法
JP5694921B2 (ja) 2009-04-20 2015-04-01 協和発酵キリン株式会社 アミノ酸変異が導入されたＩｇＧ２を有する抗体
CN103079644B (zh) 2010-06-11 2017-02-15 协和发酵麒麟株式会社 抗tim‑3抗体
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CA2874117C (en) 2012-07-02 2021-10-12 Kyowa Hakko Kirin Co., Ltd. Pharmaceutical agent comprising anti-bmp9 antibody as active ingredient for treatment of anemia such as renal anemia and cancer anemia
CN104884617B (zh) 2012-12-07 2019-02-19 协和发酵麒麟株式会社 抗folr1抗体
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CN113260745A (zh) 2019-01-09 2021-08-13 丝芭博株式会社 改造丝心蛋白
WO2020158877A1 (ja) 2019-01-31 2020-08-06 Ｓｐｉｂｅｒ株式会社 組換えタンパク質の製造方法
WO2020230901A1 (ja) 2019-05-15 2020-11-19 協和キリン株式会社 Ｃｄ４０とｇｐｃ３に結合するバイスペシフィック抗体
CA3140385A1 (en) 2019-05-15 2020-11-19 Kyowa Kirin Co., Ltd. Bispecific antibody binding to cd40 and fap
US20240279696A1 (en) 2019-12-16 2024-08-22 Kyowa Hakko Bio Co., Ltd. Microorganism having modified lactose permease, and method for producing lactose-containing oligosaccharide
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US20230128695A1 (en) 2020-03-16 2023-04-27 Spiber Inc. Synthetic Polymer and Method for Producing Same, Molding Material, and Molded Body
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US20260002181A1 (en) 2022-06-30 2026-01-01 Kirin Holdings Kabushiki Kaisha Method for producing 4-(aminomethyl)cyclohexane-1-carboxylic acid
CN119677855A (zh) 2022-08-10 2025-03-21 协和麒麟株式会社 抗fgf23抗体或该抗体片段
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Also Published As

Publication number Publication date
DE3277307D1 (en) 1987-10-22
US4686191A (en) 1987-08-11
EP0083069B1 (en) 1987-09-16
JPH0134599B2 (enExample) 1989-07-20
EP0083069A3 (en) 1984-03-28
JPS58110600A (ja) 1983-07-01
EP0083069A2 (en) 1983-07-06

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