CA1032927A - Process for the preparation of new estrone-derived haptens - Google Patents

Process for the preparation of new estrone-derived haptens

Info

Publication number
CA1032927A
CA1032927A CA202,616A CA202616A CA1032927A CA 1032927 A CA1032927 A CA 1032927A CA 202616 A CA202616 A CA 202616A CA 1032927 A CA1032927 A CA 1032927A
Authority
CA
Canada
Prior art keywords
formule
composé
que
groupement
représente
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA202,616A
Other languages
English (en)
French (fr)
Other versions
CA202616S (en
Inventor
Vesperto Torelli
Andre Pierdet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of CA1032927A publication Critical patent/CA1032927A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/823—Immunogenic carrier or carrier per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA202,616A 1973-06-18 1974-06-17 Process for the preparation of new estrone-derived haptens Expired CA1032927A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7322114A FR2235949B1 (sv) 1973-06-18 1973-06-18

Publications (1)

Publication Number Publication Date
CA1032927A true CA1032927A (en) 1978-06-13

Family

ID=9121104

Family Applications (1)

Application Number Title Priority Date Filing Date
CA202,616A Expired CA1032927A (en) 1973-06-18 1974-06-17 Process for the preparation of new estrone-derived haptens

Country Status (16)

Country Link
US (1) US3922292A (sv)
JP (4) JPS5827280B2 (sv)
AT (1) AT343295B (sv)
BE (1) BE816457A (sv)
BR (1) BR7404979D0 (sv)
CA (1) CA1032927A (sv)
DE (1) DE2429040C2 (sv)
DK (1) DK322274A (sv)
ES (3) ES427318A1 (sv)
FR (1) FR2235949B1 (sv)
GB (2) GB1478356A (sv)
IE (1) IE41524B1 (sv)
LU (1) LU70329A1 (sv)
NL (1) NL7408041A (sv)
SE (1) SE402461B (sv)
ZA (1) ZA743841B (sv)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2277821A1 (fr) * 1974-07-10 1976-02-06 Roussel Uclaf Nouveaux haptenes derives de la progesterone, leur procede de preparation et leur application a la fabrication d'antigenes
FR2377419A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 11b-substitues 1,3,5 (10) trieniques, leur procede de preparation et leur application comme medicament
FR2377417A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides substitues en 11b, ainsi que leur procede de preparation
FR2377418A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments
NL7701384A (nl) * 1977-02-10 1978-08-14 Akzo Nv Werkwijze voor het bereiden van nieuwe steroiden van de oestraanreeks.
GB8327256D0 (en) * 1983-10-12 1983-11-16 Ici Plc Steroid derivatives
DE3572177D1 (de) 1984-10-19 1989-09-14 Nihon Mediphysics Co Ltd Imunoassay for estriol-3-sulfate
FR2665901B2 (fr) * 1989-02-24 1994-07-29 Roussel Uclaf Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments.
FR2643638B1 (fr) * 1989-02-24 1991-06-14 Roussel Uclaf Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
DE69128820T2 (de) * 1990-08-14 1998-06-10 Hoechst Marion Roussel Inc Neue 19-Nor Steroide, die eine Amid tragende Gruppe in der 11-Beta-Stelle haben, ihre Herstellung, ihre Verwendung als Medikamente und pharmazeutische Präparate davon
JPH059418U (ja) * 1991-07-12 1993-02-09 広島アルミニウム工業株式会社 電磁コンロ用発熱器
JPH07297707A (ja) * 1994-04-27 1995-11-10 Nec Corp 位相同期発振回路
EP0954317B1 (en) 1996-04-09 2007-06-06 The University Of Edinburgh Use of 7 apha-substituted steroids to treat neuropsychiatric disorders
DE602005023877D1 (de) * 2004-07-27 2010-11-11 Sicor Inc Verfahren zur herstellung von 7-alpha-alkylierte 19-norsteroide
US7910755B2 (en) * 2004-09-29 2011-03-22 Harbor Biosciences, Inc. Stem cell expansion and uses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3211756A (en) * 1963-07-23 1965-10-12 Searle & Co 3-hydroxyimino-17alpha-(lower alkyl)-5alpha-androstan-17beta-ols and the optionally substituted 3-acyloxyimino and 3-alkoxyimino derivatives corresponding
DE1668682A1 (de) * 1967-03-14 1971-09-23 Searle & Co Gegebenenfalls in 17-Stellung alkylierte 11,13ss-Dialkylgona-1,3,5(10)-trien-3,17ss-diole und deren Ester

Also Published As

Publication number Publication date
LU70329A1 (sv) 1975-03-06
ATA504374A (de) 1977-09-15
AU7014874A (en) 1975-12-18
FR2235949B1 (sv) 1978-03-17
ES427318A1 (es) 1976-09-16
FR2235949A1 (sv) 1975-01-31
JPS5934200B2 (ja) 1984-08-21
BR7404979D0 (pt) 1975-01-21
DE2429040A1 (de) 1975-01-09
ES448013A1 (es) 1977-07-01
JPS6241719B2 (sv) 1987-09-04
BE816457A (fr) 1974-12-17
JPS5890597A (ja) 1983-05-30
IE41524B1 (en) 1980-01-30
IE41524L (en) 1974-12-18
JPS601200A (ja) 1985-01-07
SE7407108L (sv) 1974-12-19
JPS5827280B2 (ja) 1983-06-08
GB1478356A (en) 1977-06-29
SE402461B (sv) 1978-07-03
DE2429040C2 (de) 1985-10-31
GB1478357A (en) 1977-06-29
ES448012A1 (es) 1977-07-01
JPS5036451A (sv) 1975-04-05
NL7408041A (sv) 1974-12-20
JPS5890600A (ja) 1983-05-30
US3922292A (en) 1975-11-25
AT343295B (de) 1978-05-26
DK322274A (sv) 1975-02-10
ZA743841B (en) 1976-01-28
JPS5838440B2 (ja) 1983-08-23

Similar Documents

Publication Publication Date Title
CA1032927A (en) Process for the preparation of new estrone-derived haptens
CA2121692A1 (fr) Nouveaux derives du lupane, leur preparation et les compositions pharmaceutiques qui les contiennent
CA2238845C (fr) Nouveaux derives de 2,3,5-trimethyl-4-hydroxy anilides, leur preparation et leur application en therapeutique
CH644365A5 (fr) Octahydro-pyrazolo(3,4-g)quinoleines.
FR2485021A1 (fr) Nouveaux sterols 15-oxygenes
EP0558416B1 (fr) Nouveaux stéroides comportant en position 17 un radical méthylène lactone, leur procédé et des intermédiaires de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant
CA1260459A (fr) Procede de preparation de nouveaux steroides substitues en position 10 par un radical comportant une double ou une triple liaison
US5175320A (en) Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
AU605575B2 (en) 17 beta-(cyclopropyloxy) androst-5-en-3 beta-ol and related compounds useful as c17-20 lyase inhibitors
EP0056000B1 (fr) Dérivés 17/(alkoxycarbonyle) (formamido) méthylène/stéroides et leur préparation
CA1026318A (en) Preparation process for spirolactone steroids
CH652726A5 (fr) Derives steroides 17-oxazolines, leur procede de preparation et leur utilisation a la preparation de corticosteroides.
CA1046502A (en) Process for the preparation of new haptens derived from testosterone
CA1140110A (fr) Procede de preparation de nouveaux derives de l'androst-4-ene
EP0574317A1 (fr) Nouveau procédé de préparation de composés stéroides 20-céto 21alpha-hydroxy et intermédiaires
CA1146531A (fr) Procede de preparation de nouveaux derives 2,2- dimethyl 19-nor steroides
EP0192288B1 (fr) Nouveaux dérivés stéroides portant en 17 un radical nitrométhylène, Leur application à la préparation de produits biologiquement actifs
FR2533928A1 (fr) Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments
CA1121341A (fr) PROCEDE DE PREPARATION DE NOUVEAUX DERIVES STEROIDES 17 SPIROSULTINES, LES.gamma.-HYDROXY ACIDES CORRESPONDANTS
EP0275728A1 (fr) Nouveaux produits stéroîdes comportant, en position 23, un radical sulfinyle, leur procédé de préparation, leur application à la préparation de produits de la série des 20-cétoprégnanes et des intermédiaires de cette application
CA2098069A1 (fr) Nicotinates de diacylglycerols leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2496669A1 (fr) Nouveaux derives steroides 3-ceto4 ou1-4 substitues en position 7, leur procede de preparation et leur application comme medicaments
US5274088A (en) Method for the preparation of (25r)-26-aminocholesterol
KR100500498B1 (ko) 에스트로겐혼합물의황산화방법
CA2037092C (en) Bile acid unsaturated derivatives, processes for the preparation thereof and pharmaceutical compositions containing them