BRPI0907087A2 - ácidos nucleicos de fórmula (i) (nuglxmgnnv)a e derivados dos mesmos como um agente imunoestimulante/adjuvante - Google Patents

ácidos nucleicos de fórmula (i) (nuglxmgnnv)a e derivados dos mesmos como um agente imunoestimulante/adjuvante

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Publication number
BRPI0907087A2
BRPI0907087A2 BRPI0907087-7A BRPI0907087A BRPI0907087A2 BR PI0907087 A2 BRPI0907087 A2 BR PI0907087A2 BR PI0907087 A BRPI0907087 A BR PI0907087A BR PI0907087 A2 BRPI0907087 A2 BR PI0907087A2
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BR
Brazil
Prior art keywords
derivatives
nucleic acids
formula
immunostimulating
adjuvant
Prior art date
Application number
BRPI0907087-7A
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English (en)
Inventor
Kramps Thomas
Voss Söhnke
Probst Jochen
Hoerr Ingmar
Original Assignee
Curevac Gmbh
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Publication date
Application filed by Curevac Gmbh filed Critical Curevac Gmbh
Publication of BRPI0907087A2 publication Critical patent/BRPI0907087A2/pt
Publication of BRPI0907087B1 publication Critical patent/BRPI0907087B1/pt

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Abstract

ácidos nucleicos de fórmula (i) (ne-g1xmg„n„)a e derivados dos mesmos como um agente munoestimulante/adjuvante". a presente invenção refere-se a ácidos nucleicos da fórmula ge- ral (i): (nug,xmgnn„)a e derivados dos mesmos como um agente imunoesti-mulante / adjuvante e a composições contendo os mesmos, opcionalmente compreendendo um adjuvante adicional. a presente invenção além disso se refere a uma composição farmacêutica ou a uma vacina, cada uma contendo ácidos nucleicos de fórmula (i) acima e/ou derivados dos mesmos como um agente imunoestimulante, e opcionalmente no mínimo um componente far-maceuticamente ativo adicional, por exemplo, um agente antigênico. a pre-sente invenção se refere igualmente ao uso da composição farmacêutica ou da vacina para o tratamento de doenças cancerígenas, doenças infecciosas, alergias e doenças autoimunes, e etc. igualmente, a presente invenção inclui o uso de ácidos nucleicos da fórmula geral (i): (nugixmgnn„)a e/ou derivados dos mesmos para a preparação de uma composição farmacêutica para o tratamento de semelhantes doenças.
BRPI0907087-7A 2008-01-31 2009-01-28 Molécula de rna, composição farmacêutica e seus usos no tratamento de doenças BRPI0907087B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08001827 2008-01-31
EP08001827.8 2008-01-31
PCT/EP2009/000546 WO2009095226A2 (en) 2008-01-31 2009-01-28 Nucleic acids of formula (i) (nuglxmgnnv)a and derivatives thereof as an immunostimulating agent/adjuvant

Publications (2)

Publication Number Publication Date
BRPI0907087A2 true BRPI0907087A2 (pt) 2019-03-06
BRPI0907087B1 BRPI0907087B1 (pt) 2021-08-17

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US (4) US9226959B2 (pt)
EP (3) EP3346005A1 (pt)
JP (1) JP5721441B2 (pt)
KR (1) KR101483715B1 (pt)
CN (1) CN101932707B (pt)
AU (1) AU2009210266B2 (pt)
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CA (1) CA2710534C (pt)
DK (1) DK2176408T5 (pt)
ES (1) ES2537703T3 (pt)
HR (1) HRP20150528T2 (pt)
HU (1) HUE025027T2 (pt)
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PL (1) PL2176408T3 (pt)
PT (1) PT2176408E (pt)
RU (1) RU2545701C2 (pt)
SG (1) SG188104A1 (pt)
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