BRPI0907087A2 - ácidos nucleicos de fórmula (i) (nuglxmgnnv)a e derivados dos mesmos como um agente imunoestimulante/adjuvante - Google Patents
ácidos nucleicos de fórmula (i) (nuglxmgnnv)a e derivados dos mesmos como um agente imunoestimulante/adjuvanteInfo
- Publication number
- BRPI0907087A2 BRPI0907087A2 BRPI0907087-7A BRPI0907087A BRPI0907087A2 BR PI0907087 A2 BRPI0907087 A2 BR PI0907087A2 BR PI0907087 A BRPI0907087 A BR PI0907087A BR PI0907087 A2 BRPI0907087 A2 BR PI0907087A2
- Authority
- BR
- Brazil
- Prior art keywords
- derivatives
- nucleic acids
- formula
- immunostimulating
- adjuvant
- Prior art date
Links
- 239000002671 adjuvant Substances 0.000 title abstract 4
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 239000003795 chemical substances by application Substances 0.000 title abstract 3
- 230000003308 immunostimulating effect Effects 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000003022 immunostimulating agent Substances 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08001827 | 2008-01-31 | ||
EP08001827.8 | 2008-01-31 | ||
PCT/EP2009/000546 WO2009095226A2 (en) | 2008-01-31 | 2009-01-28 | Nucleic acids of formula (i) (nuglxmgnnv)a and derivatives thereof as an immunostimulating agent/adjuvant |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0907087A2 true BRPI0907087A2 (pt) | 2019-03-06 |
BRPI0907087B1 BRPI0907087B1 (pt) | 2021-08-17 |
Family
ID=40578060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0907087-7A BRPI0907087B1 (pt) | 2008-01-31 | 2009-01-28 | Molécula de rna, composição farmacêutica e seus usos no tratamento de doenças |
Country Status (19)
Country | Link |
---|---|
US (4) | US9226959B2 (pt) |
EP (3) | EP3346005A1 (pt) |
JP (1) | JP5721441B2 (pt) |
KR (1) | KR101483715B1 (pt) |
CN (1) | CN101932707B (pt) |
AU (1) | AU2009210266B2 (pt) |
BR (1) | BRPI0907087B1 (pt) |
CA (1) | CA2710534C (pt) |
DK (1) | DK2176408T5 (pt) |
ES (1) | ES2537703T3 (pt) |
HR (1) | HRP20150528T2 (pt) |
HU (1) | HUE025027T2 (pt) |
MX (1) | MX2010008468A (pt) |
PL (1) | PL2176408T3 (pt) |
PT (1) | PT2176408E (pt) |
RU (1) | RU2545701C2 (pt) |
SG (1) | SG188104A1 (pt) |
SI (1) | SI2176408T1 (pt) |
WO (1) | WO2009095226A2 (pt) |
Families Citing this family (216)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9393315B2 (en) | 2011-06-08 | 2016-07-19 | Nitto Denko Corporation | Compounds for targeting drug delivery and enhancing siRNA activity |
ES2647452T3 (es) | 2006-08-08 | 2017-12-21 | Rheinische Friedrich-Wilhelms-Universität Bonn | Estructura y uso de oligonucleótidos 5' fosfato |
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