BRPI0815595B8 - composição antifúngica para administração oral, que é autoemulsificante em contato com uma fase aquosa, seu uso e produto farmacêutico - Google Patents

composição antifúngica para administração oral, que é autoemulsificante em contato com uma fase aquosa, seu uso e produto farmacêutico

Info

Publication number
BRPI0815595B8
BRPI0815595B8 BRPI0815595A BRPI0815595A BRPI0815595B8 BR PI0815595 B8 BRPI0815595 B8 BR PI0815595B8 BR PI0815595 A BRPI0815595 A BR PI0815595A BR PI0815595 A BRPI0815595 A BR PI0815595A BR PI0815595 B8 BRPI0815595 B8 BR PI0815595B8
Authority
BR
Brazil
Prior art keywords
emulsifying
self
contact
aqueous phase
oral administration
Prior art date
Application number
BRPI0815595A
Other languages
English (en)
Inventor
Bucher Christian
Marchaud Delphine
Dubois Estelle
Ditzinger Günter
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Publication of BRPI0815595A2 publication Critical patent/BRPI0815595A2/pt
Publication of BRPI0815595A8 publication Critical patent/BRPI0815595A8/pt
Publication of BRPI0815595B1 publication Critical patent/BRPI0815595B1/pt
Publication of BRPI0815595B8 publication Critical patent/BRPI0815595B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

composição antifúngica. a presente invenção refere-se a uma composição farmacêutica para administração oral, que é autoemulsificante por contato com uma fase 5 aquosa, em particular, fluidos gastrointestinais, e que compreende: (a) um composto antifungicamente ativo de fórmula (i) (i) na qual r1, r2 e r3 são independentemente entre si hidrogênio, f ou cl, ou um sal de adição de ácido farmaceuticamente aceitável dele; (b) um veículo compreendendo um componente solubilizador para o componente antifungicamente eficaz (a).
BRPI0815595A 2007-08-21 2008-08-20 composição antifúngica para administração oral, que é autoemulsificante em contato com uma fase aquosa, seu uso e produto farmacêutico BRPI0815595B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07114652.6 2007-08-21
EP07114652 2007-08-21
PCT/EP2008/060905 WO2009024590A2 (en) 2007-08-21 2008-08-20 Antifungal composition

Publications (4)

Publication Number Publication Date
BRPI0815595A2 BRPI0815595A2 (pt) 2015-03-03
BRPI0815595A8 BRPI0815595A8 (pt) 2018-06-19
BRPI0815595B1 BRPI0815595B1 (pt) 2021-02-09
BRPI0815595B8 true BRPI0815595B8 (pt) 2021-05-25

Family

ID=38656753

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0815595A BRPI0815595B8 (pt) 2007-08-21 2008-08-20 composição antifúngica para administração oral, que é autoemulsificante em contato com uma fase aquosa, seu uso e produto farmacêutico

Country Status (15)

Country Link
US (1) US8536208B2 (pt)
EP (1) EP2192893B1 (pt)
JP (1) JP5576279B2 (pt)
KR (1) KR101493546B1 (pt)
CN (1) CN101784259B (pt)
AU (1) AU2008290536B2 (pt)
BR (1) BRPI0815595B8 (pt)
CA (1) CA2697328C (pt)
ES (1) ES2551125T3 (pt)
HK (1) HK1141742A1 (pt)
MX (1) MX2010001730A (pt)
PL (1) PL2192893T3 (pt)
PT (1) PT2192893E (pt)
WO (1) WO2009024590A2 (pt)
ZA (1) ZA201000925B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2856699A1 (en) * 2011-12-02 2013-06-06 Colgate-Palmolive Company Oral care composition comprising isobutyl magnolol
PT3471702T (pt) * 2016-06-20 2022-03-17 Capretto Ehf Formulação termoestável de substâncias biologicamente ativas
CN105943500B (zh) * 2016-07-08 2019-01-04 河南省立眼科医院 一种含有艾沙康唑的眼用纳米胶束抗真菌溶液
WO2018219804A1 (en) * 2017-06-02 2018-12-06 Bayer Pharma Aktiengesellschaft Self-microemulsifying drug delivery systems
WO2023219465A1 (ko) * 2022-05-12 2023-11-16 주식회사 지뉴브 안정한 액상 제약 제제

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054136A (en) 1993-09-30 2000-04-25 Gattefosse S.A. Orally administrable composition capable of providing enhanced bioavailability when ingested
NZ270418A (en) 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
WO1999045008A1 (en) 1998-03-06 1999-09-10 F. Hoffmann-La Roche Ag 3-[4-(4-cyanophenyl)thiazol-2-y)]-1-(1h-1,2,4-triazol-1-yl)-butan-2-ol derivatives having antifungal activity
EP1075252A2 (en) * 1998-05-07 2001-02-14 ELAN CORPORATION, Plc Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems
CA2388320C (en) 1999-11-02 2009-12-15 Basilea Pharmaceutica Ag N-substituted carbamoyloxyalkyl-azolium derivatives
JP2001302544A (ja) * 1999-12-10 2001-10-31 Takeda Chem Ind Ltd 経口用医薬組成物
US20030072807A1 (en) * 2000-12-22 2003-04-17 Wong Joseph Chung-Tak Solid particulate antifungal compositions for pharmaceutical use
FR2827770B1 (fr) * 2001-07-27 2005-08-19 Gattefosse Ets Sa Composition pharmaceutique a usage oral comprenant un principe actif susceptible de subir un important effet de premier passage intestinal
US20050186142A1 (en) * 2002-10-25 2005-08-25 Foamix Ltd. Kit and composition of imidazole with enhanced bioavailability
EP1498123A1 (en) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Emulsifying systems containing azetidine derivatives
FR2861992B1 (fr) * 2003-11-10 2007-07-20 Sanofi Synthelabo Composition pharmaceutique destinee a l'administration orale d'un derive de pyrazole-3-carboxamide.
JP2007515458A (ja) * 2003-12-23 2007-06-14 テイボテク・フアーマシユーチカルズ・リミテツド Ｈｉｖプロテアーゼ阻害剤の自己ミクロ乳化性薬剤送達システム
FR2873585B1 (fr) * 2004-07-27 2006-11-17 Aventis Pharma Sa Nouvelles formulations galeniques de principes actifs
RU2007123366A (ru) * 2004-11-24 2008-12-27 Мерк Энд Ко. Жидкие и полутвердые фармацевтические препаративные формы для перорального введения замещенного амида
WO2007038796A1 (en) * 2005-09-29 2007-04-05 Repros Therapeutics Inc. Formulations with improved bioavailability, comprising a steroid derivative and a polyglycolysed glyceride
JP2009514890A (ja) * 2005-11-07 2009-04-09 マーティ・ファーマシューティカルズ・インク テトラヒドロカンナビノールの改良された送達

Also Published As

Publication number Publication date
KR20100064370A (ko) 2010-06-14
KR101493546B1 (ko) 2015-02-16
CN101784259B (zh) 2013-03-27
MX2010001730A (es) 2010-03-10
WO2009024590A3 (en) 2009-06-04
PL2192893T3 (pl) 2015-12-31
CN101784259A (zh) 2010-07-21
ES2551125T3 (es) 2015-11-16
JP5576279B2 (ja) 2014-08-20
WO2009024590A2 (en) 2009-02-26
JP2010536826A (ja) 2010-12-02
PT2192893E (pt) 2015-11-09
HK1141742A1 (en) 2010-11-19
US20110281918A1 (en) 2011-11-17
AU2008290536A1 (en) 2009-02-26
EP2192893A2 (en) 2010-06-09
CA2697328A1 (en) 2009-02-26
BRPI0815595B1 (pt) 2021-02-09
BRPI0815595A2 (pt) 2015-03-03
US8536208B2 (en) 2013-09-17
AU2008290536B2 (en) 2012-02-09
EP2192893B1 (en) 2015-08-19
CA2697328C (en) 2015-08-11
ZA201000925B (en) 2010-10-27
BRPI0815595A8 (pt) 2018-06-19

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 09/02/2021, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/08/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF