BRPI0715746B8 - composto ou sal farmaceuticamente aceitável do mesmo e composição farmacêutica os compreendendo - Google Patents

composto ou sal farmaceuticamente aceitável do mesmo e composição farmacêutica os compreendendo

Info

Publication number
BRPI0715746B8
BRPI0715746B8 BRPI0715746A BRPI0715746A BRPI0715746B8 BR PI0715746 B8 BRPI0715746 B8 BR PI0715746B8 BR PI0715746 A BRPI0715746 A BR PI0715746A BR PI0715746 A BRPI0715746 A BR PI0715746A BR PI0715746 B8 BRPI0715746 B8 BR PI0715746B8
Authority
BR
Brazil
Prior art keywords
compound
treating
pharmaceutical composition
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
BRPI0715746A
Other languages
English (en)
Portuguese (pt)
Inventor
Labrecque Denis
Johnstone Shawn
Brown William
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39033277&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0715746(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BRPI0715746A2 publication Critical patent/BRPI0715746A2/pt
Publication of BRPI0715746B1 publication Critical patent/BRPI0715746B1/pt
Publication of BRPI0715746B8 publication Critical patent/BRPI0715746B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0715746A 2006-08-11 2007-08-10 composto ou sal farmaceuticamente aceitável do mesmo e composição farmacêutica os compreendendo BRPI0715746B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83724906P 2006-08-11 2006-08-11
US60/837249 2006-08-11
PCT/SE2007/000720 WO2008018827A1 (en) 2006-08-11 2007-08-10 Benzimidazole derivatives useful in treatment of vallinoid receptor trpv1 related disorders

Publications (3)

Publication Number Publication Date
BRPI0715746A2 BRPI0715746A2 (pt) 2013-07-16
BRPI0715746B1 BRPI0715746B1 (pt) 2020-09-24
BRPI0715746B8 true BRPI0715746B8 (pt) 2021-05-25

Family

ID=39033277

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0715746A BRPI0715746B8 (pt) 2006-08-11 2007-08-10 composto ou sal farmaceuticamente aceitável do mesmo e composição farmacêutica os compreendendo

Country Status (25)

Country Link
US (2) US7906654B2 (enExample)
EP (1) EP2051967B1 (enExample)
JP (1) JP5140077B2 (enExample)
KR (1) KR101412881B1 (enExample)
CN (2) CN101522637A (enExample)
AR (1) AR062299A1 (enExample)
AU (1) AU2007282186B2 (enExample)
BR (1) BRPI0715746B8 (enExample)
CA (1) CA2660529C (enExample)
CL (1) CL2007002343A1 (enExample)
CO (1) CO6150176A2 (enExample)
ES (1) ES2533971T3 (enExample)
IL (1) IL196672A0 (enExample)
MX (1) MX2009001496A (enExample)
MY (1) MY147649A (enExample)
NO (1) NO20091054L (enExample)
NZ (1) NZ575416A (enExample)
PE (1) PE20081315A1 (enExample)
RU (1) RU2458055C2 (enExample)
SG (1) SG173360A1 (enExample)
TW (1) TWI433839B (enExample)
UA (1) UA96764C2 (enExample)
UY (1) UY30533A1 (enExample)
WO (1) WO2008018827A1 (enExample)
ZA (1) ZA200900961B (enExample)

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SE0301446D0 (sv) 2003-05-16 2003-05-16 Astrazeneca Ab New Compounds
AR058705A1 (es) 2005-12-23 2008-02-20 Astrazeneca Ab Compuestos de bencimidazol como inhibidores del receptor vaniloide 1 (vr1)
TWI433839B (zh) * 2006-08-11 2014-04-11 Neomed Inst 新穎的苯并咪唑衍生物290
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
ES2539290T3 (es) 2008-04-18 2015-06-29 Daewoong Pharmaceutical Co., Ltd. Un derivado novedoso de benzoxazina bencimidazol, una composición farmacéutica que comprende el mismo y su uso
KR101293384B1 (ko) 2010-10-13 2013-08-05 주식회사 대웅제약 신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도
US8716226B2 (en) 2012-07-18 2014-05-06 Saint Louis University 3,5 phenyl-substituted beta amino acid derivatives as integrin antagonists
EP2875021B1 (en) 2012-07-18 2017-08-23 Saint Louis University Beta amino acid derivatives as integrin antagonists
JO3719B1 (ar) 2014-11-20 2021-01-31 Takeda Pharmaceuticals Co 4- أوكسو-4،3- داي هيدرو-3،2،1- بنزوترايازينات كمواد ضابطة لأجل gpr139
CN107001541B (zh) 2014-12-08 2019-11-26 罗门哈斯公司 聚烯烃添加剂、抗垂挂聚烯烃以及其制备方法
JP2018052817A (ja) * 2015-01-21 2018-04-05 大日本住友製薬株式会社 新規ベンズイミダゾール誘導体およびその医薬用途
RU2729518C2 (ru) 2015-12-30 2020-08-07 Сент-Луис Юниверсити Мета-азациклические производные аминобензойной кислоты в качестве антагонистов пан-интегрина
CA3125655A1 (en) * 2019-01-08 2020-07-16 Neomed Institute - Institut Neomed Crystalline forms of (s)-2-(7-cyano-1h-benzimidazol-1 yl)- n-{1-[4-(1-cyano-1-methylethyl)phenyl]ethyl}acetamide
CA3150508A1 (en) 2019-09-16 2021-03-25 Holger Monenschein Azole-fused pyridazin-3(2h)-one derivatives
RU2755206C1 (ru) 2020-05-20 2021-09-14 Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) Средство пролонгированного анальгетического действия и лекарственный препарат на его основе
CN117623972A (zh) * 2022-08-17 2024-03-01 上海慧聚药业有限公司 非离子型造影剂中间体的合成

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SE0301446D0 (sv) * 2003-05-16 2003-05-16 Astrazeneca Ab New Compounds
SE0301701D0 (sv) * 2003-06-10 2003-06-10 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
KR100738784B1 (ko) 2003-09-03 2007-07-12 화이자 인코포레이티드 5-ｈｔ4 수용체 효능 활성을 갖는 벤즈이미다졸론
JP4775259B2 (ja) 2004-03-31 2011-09-21 味の素株式会社 アニリン誘導体
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AR058705A1 (es) 2005-12-23 2008-02-20 Astrazeneca Ab Compuestos de bencimidazol como inhibidores del receptor vaniloide 1 (vr1)
TWI433839B (zh) 2006-08-11 2014-04-11 Neomed Inst 新穎的苯并咪唑衍生物290

Also Published As

Publication number Publication date
MX2009001496A (es) 2009-02-18
EP2051967B1 (en) 2014-12-31
US20080221188A1 (en) 2008-09-11
KR20090035701A (ko) 2009-04-10
AR062299A1 (es) 2008-10-29
AU2007282186B2 (en) 2011-07-07
CN101792436A (zh) 2010-08-04
CN101522637A (zh) 2009-09-02
AU2007282186A1 (en) 2008-02-14
US7906654B2 (en) 2011-03-15
UY30533A1 (es) 2008-03-31
BRPI0715746B1 (pt) 2020-09-24
WO2008018827A8 (en) 2009-02-19
PE20081315A1 (es) 2008-11-08
US20110137045A1 (en) 2011-06-09
CA2660529A1 (en) 2008-02-14
CA2660529C (en) 2014-10-21
TWI433839B (zh) 2014-04-11
IL196672A0 (en) 2009-11-18
RU2009103675A (ru) 2010-09-20
RU2458055C2 (ru) 2012-08-10
JP2010500345A (ja) 2010-01-07
EP2051967A1 (en) 2009-04-29
BRPI0715746A2 (pt) 2013-07-16
US8093402B2 (en) 2012-01-10
KR101412881B1 (ko) 2014-06-26
CL2007002343A1 (es) 2008-04-04
NZ575416A (en) 2011-10-28
WO2008018827A1 (en) 2008-02-14
CO6150176A2 (es) 2010-04-20
UA96764C2 (ru) 2011-12-12
SG173360A1 (en) 2011-08-29
ES2533971T3 (es) 2015-04-16
NO20091054L (no) 2009-03-09
MY147649A (en) 2012-12-31
ZA200900961B (en) 2010-07-28
EP2051967A4 (en) 2011-06-29
JP5140077B2 (ja) 2013-02-06
TW200817338A (en) 2008-04-16

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