BRPI0606252A8 - processo para a preparação de 10,11 - dihidro-10-hidroxi-5h-dibenz/b,f/azepino-5-carboxamida, processo para a preparação de 10,11-dihidro-10-oxo-5h-dibenz/b,f/azepino-5-carboxamida e processo para a preparação de 10-acetoxi-10,11-dihidro-5h-dibenz/b,f/azepino-5-carboxamida - Google Patents
processo para a preparação de 10,11 - dihidro-10-hidroxi-5h-dibenz/b,f/azepino-5-carboxamida, processo para a preparação de 10,11-dihidro-10-oxo-5h-dibenz/b,f/azepino-5-carboxamida e processo para a preparação de 10-acetoxi-10,11-dihidro-5h-dibenz/b,f/azepino-5-carboxamidaInfo
- Publication number
- BRPI0606252A8 BRPI0606252A8 BRPI0606252A BRPI0606252A BRPI0606252A8 BR PI0606252 A8 BRPI0606252 A8 BR PI0606252A8 BR PI0606252 A BRPI0606252 A BR PI0606252A BR PI0606252 A BRPI0606252 A BR PI0606252A BR PI0606252 A8 BRPI0606252 A8 BR PI0606252A8
- Authority
- BR
- Brazil
- Prior art keywords
- dibenz
- dihydro
- azepine
- carboxamide
- preparation
- Prior art date
Links
- ZFXVFMBOFIEPII-UHFFFAOYSA-N 1h-azepine-4-carboxamide Chemical compound NC(=O)C1=CC=CNC=C1 ZFXVFMBOFIEPII-UHFFFAOYSA-N 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 7
- 238000007142 ring opening reaction Methods 0.000 abstract 2
- PGAKBXJPZAOAKB-UHFFFAOYSA-N 1h-azepine-3-carboxamide Chemical compound NC(=O)C1=CNC=CC=C1 PGAKBXJPZAOAKB-UHFFFAOYSA-N 0.000 abstract 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Epoxy Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0500815.6 | 2005-01-14 | ||
GB0500815A GB2422149A (en) | 2005-01-14 | 2005-01-14 | Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide |
PCT/PT2006/000002 WO2006075925A2 (en) | 2005-01-14 | 2006-01-13 | Method for preparation of 10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azepine-5-carboxamide |
Publications (4)
Publication Number | Publication Date |
---|---|
BRPI0606252A2 BRPI0606252A2 (pt) | 2009-06-09 |
BRPI0606252A8 true BRPI0606252A8 (pt) | 2018-03-13 |
BRPI0606252B1 BRPI0606252B1 (pt) | 2020-12-08 |
BRPI0606252B8 BRPI0606252B8 (pt) | 2021-05-25 |
Family
ID=34224635
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0606252A BRPI0606252B8 (pt) | 2005-01-14 | 2006-01-13 | processo para a preparação de 10,11 - dihidro-10-hidroxi-5h-dibenz/b,f/azepino-5-carboxamida, processo para a preparação de 10,11-dihidro-10-oxo-5h-dibenz/b,f/azepino-5-carboxamida e processo para a preparação de 10-acetoxi-10,11-dihidro-5h-dibenz/b,f/azepino-5-carboxamida |
Country Status (19)
Country | Link |
---|---|
US (1) | US7834177B2 (pt) |
EP (1) | EP1846376B1 (pt) |
JP (1) | JP5634660B2 (pt) |
KR (1) | KR20070107036A (pt) |
CN (1) | CN101142191B (pt) |
AR (1) | AR052874A1 (pt) |
AU (1) | AU2006205280A1 (pt) |
BR (1) | BRPI0606252B8 (pt) |
CA (1) | CA2594869C (pt) |
CY (1) | CY1114858T1 (pt) |
DK (1) | DK1846376T3 (pt) |
ES (1) | ES2441794T3 (pt) |
GB (1) | GB2422149A (pt) |
MX (1) | MX2007008499A (pt) |
PL (1) | PL1846376T3 (pt) |
PT (1) | PT1846376E (pt) |
RU (1) | RU2418789C2 (pt) |
SI (1) | SI1846376T1 (pt) |
WO (1) | WO2006075925A2 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2422149A (en) | 2005-01-14 | 2006-07-19 | Portela & Ca Sa | Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide |
GB0515690D0 (en) | 2005-07-29 | 2005-09-07 | Portela & Ca Sa | Asymmetric catalytic reduction |
MX2008013675A (es) | 2006-04-26 | 2009-03-06 | Supernus Pharmaceuticals Inc | Preparaciones de liberacion controlada de oxcarbacepina que tienen perfil de liberacion sigmoidal. |
WO2008027557A2 (en) | 2006-08-31 | 2008-03-06 | Spherics, Inc. | Topiramate compositions and methods of enhancing its bioavailability |
JP5489719B2 (ja) | 2006-11-17 | 2014-05-14 | スパーナス ファーマシューティカルズ インコーポレイテッド | トピラマートの徐放性配合物 |
GB0700773D0 (en) | 2007-01-15 | 2007-02-21 | Portela & Ca Sa | Drug therapies |
US8372431B2 (en) | 2007-10-26 | 2013-02-12 | Bial-Portela & C.A., S.A. | Pharmaceutical composition comprising licarbazepine acetate |
RU2012106827A (ru) | 2009-07-27 | 2013-09-10 | БИАЛ-ПОРТЕЛА энд КА., С.А. | Применение производных 5н-дибенз/в, f/азепин-5-карбоксамида для лечения фибромиалгии |
WO2011117885A1 (en) * | 2010-03-23 | 2011-09-29 | Intas Pharmaceuticals Limited | Process for preparation of enantiomers of licarbazepine |
US20150065704A1 (en) | 2011-07-13 | 2015-03-05 | Ketan Hirpara | Process for the preparation and purification of eslicarbazepine acetate and intermediates thereof |
WO2014049550A1 (en) | 2012-09-26 | 2014-04-03 | Ranbaxy Laboratories Limited | Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate |
CN106699661B (zh) * | 2016-11-22 | 2019-04-09 | 大连理工大学 | 一种二苯并[c,e]氮杂-5,7(6H)-二酮化合物的制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE789320A (fr) | 1971-09-30 | 1973-03-27 | Takeda Chemical Industries Ltd | Derives de dibenzoxirenazepine |
CH633271A5 (en) | 1978-04-18 | 1982-11-30 | Ciba Geigy Ag | Process for the rearrangement of 10,11-epoxy-10,11-dihydro-5H-dibenz[b,f]azepines to give 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepines |
CH642950A5 (en) | 1979-10-30 | 1984-05-15 | Ciba Geigy Ag | Process for the preparation of 10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide |
HUT63390A (en) | 1991-12-27 | 1993-08-30 | Alkaloida Vegyeszeti Gyar | Improved process for producing 5-carbamoyl-10-oxo-10,11-dihydro-5h-dibenz/b,f/azepine |
IT1272897B (it) | 1995-01-13 | 1997-07-01 | I F C Iniziative Finanziaarie | Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide |
PT101732B (pt) * | 1995-06-30 | 1997-12-31 | Portela & Ca Sa | Novas di-hidrodibenzo<b,f>azepinas substituidas processo para a sua preparacao composicoes farmaceuticas que as contem e utilizacao dos novos compostos na preparacao de composicoes farmaceuticas empregues em doencas do sistema nervoso |
IT1283594B1 (it) | 1996-04-12 | 1998-04-22 | Trifarma Srl | Derivati della 5h-dibenz- (b,f)-azepin-5-carbossiammide, loro preparazione e uso come sostanze ad azione medicinale |
AT408224B (de) | 1999-03-15 | 2001-09-25 | Dsm Fine Chem Austria Gmbh | Verfahren zur herstellung von oxcarbazepin |
GB0112812D0 (en) * | 2001-05-25 | 2001-07-18 | Portela & Ca Sa | Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom |
GB2422149A (en) | 2005-01-14 | 2006-07-19 | Portela & Ca Sa | Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide |
-
2005
- 2005-01-14 GB GB0500815A patent/GB2422149A/en not_active Withdrawn
-
2006
- 2006-01-13 BR BRPI0606252A patent/BRPI0606252B8/pt not_active IP Right Cessation
- 2006-01-13 US US11/813,938 patent/US7834177B2/en active Active
- 2006-01-13 PL PL06700407T patent/PL1846376T3/pl unknown
- 2006-01-13 ES ES06700407.7T patent/ES2441794T3/es active Active
- 2006-01-13 MX MX2007008499A patent/MX2007008499A/es not_active Application Discontinuation
- 2006-01-13 EP EP06700407.7A patent/EP1846376B1/en active Active
- 2006-01-13 DK DK06700407.7T patent/DK1846376T3/da active
- 2006-01-13 CN CN200680008363.3A patent/CN101142191B/zh not_active Expired - Fee Related
- 2006-01-13 WO PCT/PT2006/000002 patent/WO2006075925A2/en active Application Filing
- 2006-01-13 RU RU2007130909/04A patent/RU2418789C2/ru active
- 2006-01-13 AR ARP060100152A patent/AR052874A1/es unknown
- 2006-01-13 JP JP2007551215A patent/JP5634660B2/ja not_active Expired - Fee Related
- 2006-01-13 KR KR1020077018422A patent/KR20070107036A/ko not_active Application Discontinuation
- 2006-01-13 SI SI200631719T patent/SI1846376T1/sl unknown
- 2006-01-13 PT PT67004077T patent/PT1846376E/pt unknown
- 2006-01-13 AU AU2006205280A patent/AU2006205280A1/en not_active Abandoned
- 2006-01-13 CA CA2594869A patent/CA2594869C/en active Active
-
2014
- 2014-01-07 CY CY20141100011T patent/CY1114858T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
GB2422149A (en) | 2006-07-19 |
EP1846376B1 (en) | 2013-10-09 |
DK1846376T3 (da) | 2014-01-20 |
RU2007130909A (ru) | 2009-02-20 |
JP5634660B2 (ja) | 2014-12-03 |
US20080139807A1 (en) | 2008-06-12 |
CA2594869C (en) | 2014-12-23 |
JP2008526960A (ja) | 2008-07-24 |
WO2006075925A2 (en) | 2006-07-20 |
AU2006205280A1 (en) | 2006-07-20 |
CN101142191B (zh) | 2011-07-06 |
AR052874A1 (es) | 2007-04-11 |
SI1846376T1 (sl) | 2014-03-31 |
GB0500815D0 (en) | 2005-02-23 |
BRPI0606252B8 (pt) | 2021-05-25 |
US7834177B2 (en) | 2010-11-16 |
MX2007008499A (es) | 2007-09-07 |
CA2594869A1 (en) | 2006-07-20 |
ES2441794T3 (es) | 2014-02-06 |
WO2006075925A3 (en) | 2006-08-24 |
KR20070107036A (ko) | 2007-11-06 |
CN101142191A (zh) | 2008-03-12 |
PL1846376T3 (pl) | 2014-03-31 |
RU2418789C2 (ru) | 2011-05-20 |
EP1846376A2 (en) | 2007-10-24 |
PT1846376E (pt) | 2014-01-10 |
BRPI0606252B1 (pt) | 2020-12-08 |
CY1114858T1 (el) | 2016-12-14 |
BRPI0606252A2 (pt) | 2009-06-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0606252A8 (pt) | processo para a preparação de 10,11 - dihidro-10-hidroxi-5h-dibenz/b,f/azepino-5-carboxamida, processo para a preparação de 10,11-dihidro-10-oxo-5h-dibenz/b,f/azepino-5-carboxamida e processo para a preparação de 10-acetoxi-10,11-dihidro-5h-dibenz/b,f/azepino-5-carboxamida | |
AR059122A1 (es) | Produccion de olefinas livianas a traves de dimetileter | |
CL2009001038S1 (es) | Luminaria formada por un cuerpo cilindrico que posee en su cara superior un cuerpo troncoconico de 23u. de alto; desde el manto aparece una pieza semi anular desde la que emerge un paralelepipedo recto que remata en una zona cilindrica hueca. | |
ECSP066539A (es) | Derivados 1-amino-2-oxi sustituidos del tetrahidronaftaleno, procedimiento para su preparación y su uso como antiinflamatorio | |
BRPI0508398A (pt) | caixa de embalagem | |
EA201200059A1 (ru) | Расширяющая матрица и способ формообразования емкостей | |
BRPI0411268B8 (pt) | processo para a preparação de compostos 3-aril butil-amina substituído | |
AR051572A1 (es) | Produccion de gas libre mediante conversion de hidratos de gas | |
AR057305A1 (es) | Proceso para la preparacion de derivados de sulfamida | |
BR0110695B1 (pt) | processo para a produÇço de isopropanol de pureza ultra-alta. | |
NI200500164A (es) | Nueva difenilazetidinona con caracteristicas fisiologicas mejoradas, correspondiente metodo de produccion, medicamentos que contienen dicho compuesto y su uso. | |
BRPI1011532A2 (pt) | processo para produzir uma corrente de gá de síntese purificada de uma corrente de gás de síntese de alimentação,e , uso do gás de síntese mais purificado. | |
BRPI0516022A (pt) | tubulação composta tendo pelo menos uma peça terminal metálica e método de manufaturamento de tal tubulação | |
AR052967A1 (es) | Un protector para los extremos de un elemento tubular y elemento tubular que lo comprende | |
BRPI0515186A (pt) | derivados de alquilideno-tetrahidronaftaleno, processo para a sua produção e seu uso como antiinflamatório | |
AR051341A1 (es) | Proceso para la preparacion de derivados de [1,4,5]-oxadiazepina | |
BRPI0513165A (pt) | catalisador para a produção de uma cicloolefina por hidrogenação parcial de um hidrocarboneto aromático monocìclico, e, processo de produção do mesmo | |
ES2169575T3 (es) | Soporte de datos con un estado fundamental reproducible de datos basicos y procedimiento para su realizacion. | |
BR0210019A (pt) | Processo para a preparação de um composto | |
BRPI0410619A (pt) | processo para a produção de um flange de conexão anular, e, flange de conexão anular | |
DE602006005240D1 (de) | Herstellungsverfahren für aztreonam | |
ATE424630T1 (de) | Wellenleiterübergang und herstellungsverfahren dafür | |
TW200716555A (en) | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | |
GT200600010A (es) | Procedimientos para la preparacion de alcoholes aminoetoxibencilicos | |
UY29400A1 (es) | Base libre de lercanidipina. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: BIAL-PORTELA AND CA, S.A. (PT) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/12/2020, OBSERVADAS AS CONDICOES LEGAIS. |
|
B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 13/01/2006 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 18A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2757 DE 07-11-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |