BRPI0413354A - método e dispositivo para intensificar fluxo de agente transdérmico - Google Patents
método e dispositivo para intensificar fluxo de agente transdérmicoInfo
- Publication number
- BRPI0413354A BRPI0413354A BRPI0413354-4A BRPI0413354A BRPI0413354A BR PI0413354 A BRPI0413354 A BR PI0413354A BR PI0413354 A BRPI0413354 A BR PI0413354A BR PI0413354 A BRPI0413354 A BR PI0413354A
- Authority
- BR
- Brazil
- Prior art keywords
- microprojections
- transdermal agent
- microprojection
- agent flux
- enhancing transdermal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B10/0064—Devices for taking samples of body liquids for taking sweat or sebum samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B2010/0009—Testing for drug or alcohol abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Prostheses (AREA)
Abstract
"MéTODO E DISPOSITIVO PARA INTENSIFICAR FLUXO DE AGENTE TRANSDéRMICO". A presente invenção refere-se a um arranjo de microprojeção tendo pelo menos primeira (62) e segunda (64) microprojeções, as primeira e segunda microprojeções tendo faces internas (67a, b) e externas (65a, b), a face interna da primeira microprojeção estando disposta substancialmente paralela à face interna da segunda microprojeção; e um revestimento bio-compatível disposto nas faces internas das primeira e segunda microprojeções, as primeira e segunda microprojeções estando adaptadas para substancialmente restringir o contato do revestimento com o tecido biológico durante a inserção das primeira e segunda microprojeções no tecido.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49261003P | 2003-08-04 | 2003-08-04 | |
PCT/US2004/025169 WO2005016441A1 (en) | 2003-08-04 | 2004-08-03 | Method and device for enhancing transdermal agent flux |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0413354A true BRPI0413354A (pt) | 2006-10-10 |
Family
ID=34193137
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0413354-4A BRPI0413354A (pt) | 2003-08-04 | 2004-08-03 | método e dispositivo para intensificar fluxo de agente transdérmico |
BRPI0413360-9A BRPI0413360A (pt) | 2003-08-04 | 2004-08-03 | método e dispositivo para aumentar o fluxo de agentes transdérmicos |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0413360-9A BRPI0413360A (pt) | 2003-08-04 | 2004-08-03 | método e dispositivo para aumentar o fluxo de agentes transdérmicos |
Country Status (13)
Country | Link |
---|---|
US (2) | US20050049549A1 (pt) |
EP (2) | EP1654030A1 (pt) |
JP (2) | JP2007501071A (pt) |
KR (2) | KR20060115716A (pt) |
CN (2) | CN1863572A (pt) |
AR (2) | AR045205A1 (pt) |
AU (2) | AU2004264319A1 (pt) |
BR (2) | BRPI0413354A (pt) |
CA (2) | CA2534821A1 (pt) |
MX (2) | MXPA06001409A (pt) |
SG (2) | SG130190A1 (pt) |
TW (2) | TW200514596A (pt) |
WO (2) | WO2005016440A1 (pt) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6908453B2 (en) * | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
CN102872526A (zh) | 2002-07-19 | 2013-01-16 | 3M创新有限公司 | 微针装置和微针施用设备 |
TW200514596A (en) * | 2003-08-04 | 2005-05-01 | Alza Corp | Method and device for enhancing transdermal agent flux |
JP2007503268A (ja) * | 2003-08-25 | 2007-02-22 | スリーエム イノベイティブ プロパティズ カンパニー | 免疫応答修飾化合物の送達 |
JP2007523771A (ja) * | 2004-02-23 | 2007-08-23 | スリーエム イノベイティブ プロパティズ カンパニー | マイクロニードルアレイの成形方法 |
JP5007427B2 (ja) * | 2004-05-13 | 2012-08-22 | アルザ コーポレイション | 副甲状腺ホルモン剤の経皮送達のための装置および方法 |
TW200616660A (en) * | 2004-08-11 | 2006-06-01 | Alza Corp | Apparatus and method for transdermal delivery of natriuretic peptides |
RU2407751C2 (ru) | 2004-10-27 | 2010-12-27 | Юниверсити Оф Денвер | Аналоги адренокортикотропного гормона и относящиеся к ним методы |
US8057842B2 (en) | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
AU2005306426B2 (en) * | 2004-11-18 | 2011-04-28 | 3M Innovative Properties Company | Masking method for coating a microneedle array |
WO2006055844A2 (en) | 2004-11-18 | 2006-05-26 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
AU2006230308A1 (en) * | 2005-03-28 | 2006-10-05 | Alza Corporation | Microprojections with capillary control features and method |
WO2007002523A2 (en) * | 2005-06-24 | 2007-01-04 | 3M Innovative Properties Company | Collapsible patch with microneedle array |
US20090130127A1 (en) | 2005-08-01 | 2009-05-21 | Seiji Tokumoto | Adjuvant or Pharmaceutical Preparation for Transdermal or Transmucousal Administration |
US20070078414A1 (en) | 2005-08-05 | 2007-04-05 | Mcallister Devin V | Methods and devices for delivering agents across biological barriers |
EP1948139A4 (en) * | 2005-11-18 | 2012-04-04 | 3M Innovative Properties Co | COATING COMPOSITIONS, COATINGS DERIVED THEREFROM, AND MICRO-NETWORKS COMPRISING SUCH COATINGS |
US7658728B2 (en) * | 2006-01-10 | 2010-02-09 | Yuzhakov Vadim V | Microneedle array, patch, and applicator for transdermal drug delivery |
JPWO2007091608A1 (ja) | 2006-02-10 | 2009-07-02 | 久光製薬株式会社 | マイクロニードル付き経皮薬物投与装置 |
JP5049268B2 (ja) * | 2006-04-07 | 2012-10-17 | 久光製薬株式会社 | マイクロニードルデバイスおよびマイクロニードル付き経皮薬物投与装置 |
US7785301B2 (en) * | 2006-11-28 | 2010-08-31 | Vadim V Yuzhakov | Tissue conforming microneedle array and patch for transdermal drug delivery or biological fluid collection |
JP5275047B2 (ja) | 2007-01-31 | 2013-08-28 | 久光製薬株式会社 | 経皮または経粘膜投与のためのアジュバントおよびこれを含む医薬製剤 |
AU2014200648B2 (en) * | 2007-04-16 | 2015-09-24 | Corium Pharma Solutions, Inc. | Solvent-cast microneedle arrays containing active |
US9114238B2 (en) * | 2007-04-16 | 2015-08-25 | Corium International, Inc. | Solvent-cast microprotrusion arrays containing active ingredient |
CA2988753A1 (en) * | 2007-08-06 | 2009-02-12 | Serenity Pharmaceuticals, Llc | Methods and devices for desmopressin drug delivery |
WO2009048607A1 (en) | 2007-10-10 | 2009-04-16 | Corium International, Inc. | Vaccine delivery via microneedle arrays |
WO2010006186A1 (en) * | 2008-07-09 | 2010-01-14 | Grantadler Corporation | Needle for subcutaneous port |
KR101634836B1 (ko) | 2008-12-26 | 2016-06-29 | 히사미쓰 세이야꾸 가부시키가이샤 | 마이크로 니들 디바이스 |
WO2010124255A2 (en) * | 2009-04-24 | 2010-10-28 | Corium International, Inc. | Methods for manufacturing microprojection arrays |
RU2539991C2 (ru) * | 2009-12-16 | 2015-01-27 | Кронтек Фарма Аб | Впрыскивающие игла и устройство |
JP6327852B2 (ja) | 2010-05-04 | 2018-05-23 | コリウム インターナショナル, インコーポレイテッド | 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス |
CN101961508A (zh) * | 2010-09-30 | 2011-02-02 | 浙江大学 | 一种聚电解质复合涂层的制备方法 |
US20130331792A1 (en) * | 2011-01-18 | 2013-12-12 | The Brigham And Women's Hospital, Inc. | Device and uses thereof |
US20140037694A1 (en) | 2011-02-25 | 2014-02-06 | Hisamitsu Pharmaceutical Co., Inc. | Adjuvant for transdermal or transmucosal administration and pharmaceutical preparation containing same |
CN103717249B (zh) | 2011-06-15 | 2017-03-22 | 克洛恩泰克制药股份公司 | 注射针和装置 |
US9944019B2 (en) * | 2012-05-01 | 2018-04-17 | University of Pittsburgh—of the Commonwealth System of Higher Education | Tip-loaded microneedle arrays for transdermal insertion |
AU2013364053B2 (en) | 2012-12-21 | 2018-08-30 | Corium Pharma Solutions, Inc. | Microarray for delivery of therapeutic agent and methods of use |
BR122020006959B1 (pt) | 2013-03-12 | 2022-04-26 | Corium, Inc | Aplicador de microprojeções |
EP2968119B1 (en) | 2013-03-15 | 2019-09-18 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
JP2016514133A (ja) | 2013-03-15 | 2016-05-19 | コリウム インターナショナル, インコーポレイテッド | ポリマーを含まない微細構造物を含むマイクロアレイ、製造方法および使用方法 |
BR112015022625B1 (pt) | 2013-03-15 | 2023-01-31 | Corium, Inc | Aparelho de microestrutura para entrega de agente terapêutico |
CA2903459C (en) | 2013-03-15 | 2024-02-20 | Corium International, Inc. | Multiple impact microprojection applicators and methods of use |
WO2015009531A1 (en) * | 2013-07-16 | 2015-01-22 | 3M Innovative Properties Company | Article comprising a microneedle |
US10232157B2 (en) * | 2013-07-16 | 2019-03-19 | 3M Innovative Properties Company | Hollow microneedle with beveled tip |
EP3021929B1 (en) * | 2013-07-16 | 2020-02-26 | 3M Innovative Properties Company | Hollow microneedle with bevel opening |
WO2015033959A1 (ja) * | 2013-09-06 | 2015-03-12 | 久光製薬株式会社 | マイクロニードル・シート |
US9993549B2 (en) | 2013-10-31 | 2018-06-12 | Hisamitsu Pharmaceutical Co., Inc. | Adjuvant composition, adjuvant preparation containing same, and kit |
EP2905047A1 (de) | 2014-02-10 | 2015-08-12 | LTS LOHMANN Therapie-Systeme AG | Mikronadelsystem und Verfahren seiner Herstellung |
EP3111987B1 (en) * | 2014-02-27 | 2022-04-20 | Hisamitsu Pharmaceutical Co., Inc. | Microneedle sheet |
US9138191B1 (en) * | 2014-07-09 | 2015-09-22 | Qualcomm Incorporated | Integrated circuit module with lead frame micro-needles |
EP3188714A1 (en) | 2014-09-04 | 2017-07-12 | Corium International, Inc. | Microstructure array, methods of making, and methods of use |
KR102172135B1 (ko) | 2014-12-05 | 2020-10-30 | 히사미쓰 세이야꾸 가부시키가이샤 | 마이크로니들 디바이스 시스템 |
US10441768B2 (en) | 2015-03-18 | 2019-10-15 | University of Pittsburgh—of the Commonwealth System of Higher Education | Bioactive components conjugated to substrates of microneedle arrays |
JP2015192879A (ja) * | 2015-06-19 | 2015-11-05 | ニプロ株式会社 | ワクチン接種針 |
WO2017004067A1 (en) | 2015-06-29 | 2017-01-05 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
US11684763B2 (en) | 2015-10-16 | 2023-06-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices |
WO2017120322A1 (en) | 2016-01-05 | 2017-07-13 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Skin microenvironment targeted delivery for promoting immune and other responses |
JP2019511255A (ja) * | 2016-01-11 | 2019-04-25 | バーンダリ,インク. | マイクロニードル組成物およびそれを使用する方法 |
EP3412331B1 (en) * | 2016-02-04 | 2020-04-29 | Toppan Printing Co., Ltd. | Microneedle |
US10939912B2 (en) * | 2016-03-01 | 2021-03-09 | Kitotech Medical, Inc. | Microstructure-based systems, apparatus, and methods for wound closure |
JP6717638B2 (ja) * | 2016-03-31 | 2020-07-01 | 花王株式会社 | 開孔部を有する微細中空突起具の製造方法 |
WO2017176069A2 (ko) * | 2016-04-07 | 2017-10-12 | 랩앤피플주식회사 | 생체흡수성 금속을 이용한 마이크로 니들 |
KR20170115429A (ko) * | 2016-04-07 | 2017-10-17 | 랩앤피플주식회사 | 생체분해성 금속을 이용한 마이크로 니들 |
CN108403617A (zh) * | 2018-02-24 | 2018-08-17 | 中山大学 | 曲安奈德可溶性微针及其制备方法 |
KR102291392B1 (ko) * | 2018-03-30 | 2021-08-20 | 랩앤피플주식회사 | 멀티형 마이크로 니들 |
CN112351809B (zh) * | 2018-06-26 | 2023-07-14 | 久光制药株式会社 | 微针装置及其制造方法 |
CN110664439B (zh) * | 2019-09-05 | 2021-07-27 | 华中科技大学 | 一种可提取皮肤组织液的微针及其制备方法 |
US11986613B2 (en) | 2020-02-19 | 2024-05-21 | Kitotech Medical, Inc. | Microstructure systems and methods for pain treatment |
CN116723879A (zh) * | 2020-12-30 | 2023-09-08 | 佐治亚科技研究公司 | 用于诱导汗液以进行医学诊断的方法和装置 |
WO2023159181A1 (en) | 2022-02-18 | 2023-08-24 | Kitotech Medical, Inc. | Force modulating deep skin staples and instruments |
Family Cites Families (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE25637E (en) * | 1964-09-08 | Means for vaccinating | ||
US3123212A (en) * | 1964-03-03 | Multiple disposable intracutaneous injector package | ||
US2619962A (en) * | 1948-02-19 | 1952-12-02 | Res Foundation | Vaccination appliance |
US2893392A (en) * | 1958-01-08 | 1959-07-07 | American Cyanamid Co | Article of manufacture for intracutaneous injections |
US3072122A (en) * | 1959-01-15 | 1963-01-08 | Rosenthal Sol Roy | Package for transcutaneous injection |
US3034507A (en) * | 1960-05-10 | 1962-05-15 | American Cyanamid Co | Intracutaneous injection device |
US3221739A (en) * | 1962-03-26 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
US3221740A (en) * | 1962-08-31 | 1965-12-07 | Rosenthal Sol Roy | Injection device |
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
US3678150A (en) * | 1971-07-27 | 1972-07-18 | American Cyanamid Co | Process for improving the stability of ppd, qt and histoplasmin on tine applicators |
BE795384A (fr) * | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
US6559123B1 (en) * | 1985-04-19 | 2003-05-06 | Osi Pharmaceuticals, Inc. | Tissue-derived tumor growth inhibitors, methods of preparation and uses thereof |
SE8501990D0 (sv) * | 1985-04-24 | 1985-04-24 | Pharmacia Ab | Beleggningsforfarande |
US5080646A (en) * | 1988-10-03 | 1992-01-14 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
US5169382A (en) * | 1988-10-03 | 1992-12-08 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
US5147296A (en) * | 1988-10-03 | 1992-09-15 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
EP0429842B1 (en) * | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US5205023A (en) * | 1990-04-18 | 1993-04-27 | Hunter Robert M | Child-resistant buckle and buckle guard combination |
US6586006B2 (en) * | 1994-08-04 | 2003-07-01 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
US6033582A (en) * | 1996-01-22 | 2000-03-07 | Etex Corporation | Surface modification of medical implants |
ZA975326B (en) * | 1996-06-18 | 1998-01-14 | Alza Corp | Device and method for enhancing transdermal flux of agents being delivered or sampled. |
US5741554A (en) * | 1996-07-26 | 1998-04-21 | Bio Dot, Inc. | Method of dispensing a liquid reagent |
US5916524A (en) * | 1997-07-23 | 1999-06-29 | Bio-Dot, Inc. | Dispensing apparatus having improved dynamic range |
US5743960A (en) * | 1996-07-26 | 1998-04-28 | Bio-Dot, Inc. | Precision metered solenoid valve dispenser |
US6918901B1 (en) * | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
KR100572539B1 (ko) * | 1997-12-11 | 2006-04-24 | 알자 코포레이션 | 경피성 작용제 유동률을 증진시키기 위한 장치 |
ATE406935T1 (de) * | 1997-12-11 | 2008-09-15 | Alza Corp | Vorrichtung zur verbesserung des transdermalen flusses von medikamenten |
CA2313698C (en) * | 1997-12-11 | 2008-04-15 | Alza Corporation | Device for enhancing transdermal agent flux |
US6091975A (en) * | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
GB9817662D0 (en) * | 1998-08-13 | 1998-10-07 | Crocker Peter J | Substance delivery |
WO2000012173A1 (en) * | 1998-08-31 | 2000-03-09 | Johnson & Johnson Consumer Companies, Inc. | Electrotransport device comprising blades |
EP1187653B1 (en) * | 1999-06-04 | 2010-03-31 | Georgia Tech Research Corporation | Devices for enhanced microneedle penetration of biological barriers |
US6256533B1 (en) * | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
US6533949B1 (en) * | 2000-08-28 | 2003-03-18 | Nanopass Ltd. | Microneedle structure and production method therefor |
IL155375A0 (en) * | 2000-10-13 | 2003-11-23 | Alza Corp | Microblade array impact applicator |
AU9682801A (en) * | 2000-10-13 | 2002-04-22 | Alza Corp | Apparatus and method for piercing skin with microprotrusions |
HUP0303576A2 (en) * | 2000-10-13 | 2004-01-28 | Alza Corp | Microprotrusion member retainer for impact applicator |
HUP0302924A2 (en) * | 2000-10-26 | 2003-12-29 | Alza Corp | Transdermal drug delivery devices having coated microprotrusions |
US6855372B2 (en) * | 2001-03-16 | 2005-02-15 | Alza Corporation | Method and apparatus for coating skin piercing microprojections |
US20020193729A1 (en) * | 2001-04-20 | 2002-12-19 | Cormier Michel J.N. | Microprojection array immunization patch and method |
CN100349632C (zh) * | 2001-04-20 | 2007-11-21 | 阿尔扎公司 | 具有包含有益药剂的涂层的微小突出物阵列 |
US7429258B2 (en) * | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
US20030199810A1 (en) * | 2001-11-30 | 2003-10-23 | Trautman Joseph Creagan | Methods and apparatuses for forming microprojection arrays |
HUP0402605A2 (hu) * | 2001-12-20 | 2005-06-28 | Alza Corporation | Eszköz mikroszkopikus bemetszések ejtésére állat bőrszövetén |
US20030231984A1 (en) * | 2002-05-07 | 2003-12-18 | Bright Frank V. | Method to rapidly prepare and screen formulations and compositions containing same |
AU2003279641B2 (en) * | 2002-06-28 | 2009-06-18 | Alza Corporation | Transdermal drug delivery devices having coated microprotrusions |
AR042815A1 (es) * | 2002-12-26 | 2005-07-06 | Alza Corp | Dispositivo de suministro de agente activo que tiene miembros compuestos |
EP1638523B8 (en) * | 2003-06-30 | 2013-12-25 | ALZA Corporation | Formulations for coated microprojections containing non-volatile counterions |
TW200514596A (en) * | 2003-08-04 | 2005-05-01 | Alza Corp | Method and device for enhancing transdermal agent flux |
-
2004
- 2004-08-03 TW TW093123148A patent/TW200514596A/zh unknown
- 2004-08-03 JP JP2006522696A patent/JP2007501071A/ja not_active Withdrawn
- 2004-08-03 EP EP04780069A patent/EP1654030A1/en not_active Withdrawn
- 2004-08-03 CA CA002534821A patent/CA2534821A1/en not_active Abandoned
- 2004-08-03 KR KR1020067002472A patent/KR20060115716A/ko not_active Application Discontinuation
- 2004-08-03 MX MXPA06001409A patent/MXPA06001409A/es unknown
- 2004-08-03 BR BRPI0413354-4A patent/BRPI0413354A/pt not_active IP Right Cessation
- 2004-08-03 WO PCT/US2004/025168 patent/WO2005016440A1/en active Application Filing
- 2004-08-03 AU AU2004264319A patent/AU2004264319A1/en not_active Abandoned
- 2004-08-03 KR KR1020067002473A patent/KR20060115717A/ko not_active Application Discontinuation
- 2004-08-03 CN CNA200480028968XA patent/CN1863572A/zh active Pending
- 2004-08-03 AU AU2004264320A patent/AU2004264320A1/en not_active Abandoned
- 2004-08-03 MX MXPA06001414A patent/MXPA06001414A/es unknown
- 2004-08-03 US US10/911,299 patent/US20050049549A1/en not_active Abandoned
- 2004-08-03 TW TW093123149A patent/TW200514593A/zh unknown
- 2004-08-03 SG SG200700812-1A patent/SG130190A1/en unknown
- 2004-08-03 BR BRPI0413360-9A patent/BRPI0413360A/pt not_active IP Right Cessation
- 2004-08-03 US US10/910,889 patent/US20050031676A1/en not_active Abandoned
- 2004-08-03 JP JP2006522695A patent/JP2007501070A/ja not_active Withdrawn
- 2004-08-03 CN CNA2004800289533A patent/CN1863571A/zh active Pending
- 2004-08-03 CA CA002534823A patent/CA2534823A1/en not_active Abandoned
- 2004-08-03 WO PCT/US2004/025169 patent/WO2005016441A1/en active Application Filing
- 2004-08-03 AR ARP040102762A patent/AR045205A1/es not_active Application Discontinuation
- 2004-08-03 SG SG200700813-9A patent/SG130191A1/en unknown
- 2004-08-03 EP EP04780070A patent/EP1656178A1/en not_active Withdrawn
- 2004-08-03 AR ARP040102763A patent/AR045206A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2005016441A1 (en) | 2005-02-24 |
MXPA06001409A (es) | 2006-08-25 |
CA2534821A1 (en) | 2005-02-24 |
EP1654030A1 (en) | 2006-05-10 |
KR20060115717A (ko) | 2006-11-09 |
JP2007501071A (ja) | 2007-01-25 |
AU2004264319A1 (en) | 2005-02-24 |
KR20060115716A (ko) | 2006-11-09 |
US20050049549A1 (en) | 2005-03-03 |
JP2007501070A (ja) | 2007-01-25 |
AU2004264320A1 (en) | 2005-02-24 |
CA2534823A1 (en) | 2005-02-24 |
WO2005016440A1 (en) | 2005-02-24 |
CN1863571A (zh) | 2006-11-15 |
CN1863572A (zh) | 2006-11-15 |
BRPI0413360A (pt) | 2006-10-10 |
SG130191A1 (en) | 2007-03-20 |
EP1656178A1 (en) | 2006-05-17 |
SG130190A1 (en) | 2007-03-20 |
AR045205A1 (es) | 2005-10-19 |
AR045206A1 (es) | 2005-10-19 |
TW200514593A (en) | 2005-05-01 |
US20050031676A1 (en) | 2005-02-10 |
TW200514596A (en) | 2005-05-01 |
MXPA06001414A (es) | 2006-08-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0413354A (pt) | método e dispositivo para intensificar fluxo de agente transdérmico | |
DE60218170D1 (de) | Durchstechvorrichtung | |
ES2485940T3 (es) | Combinación de vacunas contra Meningitis B/C | |
BRPI0409945A (pt) | forma de dosagem resistente à alteração | |
WO2003009884A3 (en) | Elongated syringe | |
DE602008003713D1 (de) | Haltemuffe mit Manschette zur Einführung in subkutane Regionen | |
CY1109972T1 (el) | Χρηση τοξινης αλλαντιασης για τη θεραπευτικη αγωγη του πονου της νεραλγιας | |
WO2001036486A3 (en) | Scfv antibodies against disease associated molecules | |
NO20014746D0 (no) | Smertelindrende middel | |
KR970702705A (ko) | 수술도구 운반, 조종 및 추출을 위한 의료형 선형 액추에이터(medical linear actuator for surgical delivery. manuipulation. and extraction) | |
BR0015992A (pt) | Compostos, utilização dos mesmos, e, associações terapêuticas | |
ATE494041T1 (de) | Gewebe-haltesystem für medizinische ultraschallbehandlung | |
DE10046110B8 (de) | Medizinisches Diagnosegerät mit Patientenerkennung | |
DE60121316D1 (de) | Vorrichtung zur positionierung, untersuchung und/oder behandlung, insbesondere im gebiet der endoskopie und/oder minimal invasiver chirurgie | |
PT1296711E (pt) | E7 de vph para o tratamento do virus do papiloma humano | |
BR0313292A (pt) | Método de provimento de suporte semelhante a ligamento entre dois locais espeçados no corpo de um paciente, âncora de tecido, prendedor, dispositivo de inserção e respectivos pares | |
ATE516838T1 (de) | Medizinische vorrichtung mit schubkraftbegrenzung | |
SE0100284D0 (sv) | Medical communication system | |
NO976063L (no) | Fremgangsmåte for behandling av diabetes | |
BR0209046A (pt) | Disposição de microprojeção que possui um agente benéfico contendo revestimento | |
EP2272545A3 (en) | Antimicrobial medical devices and methods of preparation thereof | |
WO2007041063A3 (en) | Fluid sample transport devices and methods | |
BR0114551B1 (pt) | método e disposição para tratamento de fluido. | |
WO2004004757A8 (en) | Treatment for eye disorder | |
ATE384519T1 (de) | Hemmer-darstellende mittel |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012. |