BRPI0307267B8 - uso de compostos inibidores de beta-lactamases e composições farmacêuticas para terapia antibacteriana - Google Patents

uso de compostos inibidores de beta-lactamases e composições farmacêuticas para terapia antibacteriana

Info

Publication number
BRPI0307267B8
BRPI0307267B8 BRPI0307267A BR0307267A BRPI0307267B8 BR PI0307267 B8 BRPI0307267 B8 BR PI0307267B8 BR PI0307267 A BRPI0307267 A BR PI0307267A BR 0307267 A BR0307267 A BR 0307267A BR PI0307267 B8 BRPI0307267 B8 BR PI0307267B8
Authority
BR
Brazil
Prior art keywords
beta
pharmaceutical compositions
inhibitor compounds
lactamase inhibitor
antibacterial therapy
Prior art date
Application number
BRPI0307267A
Other languages
English (en)
Other versions
BRPI0307267B1 (pt
BR0307267A (pt
Inventor
Fromentin Claude
Alan Rowlands David
Aszodi Jozsef
Lampilas Maxime
Original Assignee
Astra Zeneca Holding France
Aventis Pharma Sa
Novexel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27619669&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0307267(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Zeneca Holding France, Aventis Pharma Sa, Novexel filed Critical Astra Zeneca Holding France
Publication of BR0307267A publication Critical patent/BR0307267A/pt
Publication of BRPI0307267B1 publication Critical patent/BRPI0307267B1/pt
Publication of BRPI0307267B8 publication Critical patent/BRPI0307267B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

"compostos heterocíclicos, ativos como inibidores de beta-lacta-mases". a invenção refere-se ao uso compostos de fórmula (i) e seus sais farmaceuticamente aceitáveis na preparação de um medicamento destinado a inibir a produção de <225>-lactamases por bactérias patogênicas.
BRPI0307267A 2002-01-28 2003-01-27 uso de compostos inibidores de beta-lactamases e composições farmacêuticas para terapia antibacteriana BRPI0307267B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0200951A FR2835186B1 (fr) 2002-01-28 2002-01-28 Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases
PCT/FR2003/000243 WO2003063864A2 (fr) 2002-01-28 2003-01-27 Composes heterocycliques, actifs comme inhibiteurs de beta-lactamases

Publications (3)

Publication Number Publication Date
BR0307267A BR0307267A (pt) 2004-12-07
BRPI0307267B1 BRPI0307267B1 (pt) 2016-02-10
BRPI0307267B8 true BRPI0307267B8 (pt) 2021-05-25

Family

ID=27619669

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0307267A BRPI0307267B8 (pt) 2002-01-28 2003-01-27 uso de compostos inibidores de beta-lactamases e composições farmacêuticas para terapia antibacteriana

Country Status (45)

Country Link
US (4) US7612087B2 (pt)
EP (2) EP2279737B1 (pt)
JP (1) JP4472346B2 (pt)
KR (1) KR100979079B1 (pt)
CN (3) CN100563653C (pt)
AR (2) AR038234A1 (pt)
AT (1) ATE484281T1 (pt)
AU (1) AU2003214335B2 (pt)
BE (1) BE2016C069I2 (pt)
BR (1) BRPI0307267B8 (pt)
CA (1) CA2474043C (pt)
CL (1) CL2011000009A1 (pt)
CO (1) CO5601014A2 (pt)
CR (2) CR7387A (pt)
CY (3) CY1111061T1 (pt)
DE (1) DE60334527D1 (pt)
DK (2) DK2279737T3 (pt)
EA (1) EA007220B1 (pt)
EC (1) ECSP045193A (pt)
ES (2) ES2356813T3 (pt)
FR (1) FR2835186B1 (pt)
HK (2) HK1077205A1 (pt)
HR (1) HRP20040686B1 (pt)
HU (1) HUS1600055I1 (pt)
IL (1) IL163167A (pt)
JO (1) JO2646B1 (pt)
LT (1) LTC1480644I2 (pt)
MA (1) MA26351A1 (pt)
MX (1) MXPA04006621A (pt)
MY (1) MY140638A (pt)
NL (1) NL300847I2 (pt)
NO (2) NO335195B1 (pt)
NZ (1) NZ533936A (pt)
OA (1) OA12761A (pt)
PE (1) PE20030969A1 (pt)
PL (1) PL220725B1 (pt)
PT (2) PT2279737E (pt)
RS (1) RS52137B (pt)
SI (2) SI1480644T1 (pt)
TN (1) TNSN04137A1 (pt)
TW (1) TWI293071B (pt)
UA (1) UA80271C2 (pt)
UY (1) UY27626A1 (pt)
WO (1) WO2003063864A2 (pt)
ZA (1) ZA200405607B (pt)

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HRP20040686B1 (hr) 2013-02-28
CR7387A (es) 2010-10-25
DE60334527D1 (de) 2010-11-25
MA26351A1 (fr) 2004-10-01
CN1655781A (zh) 2005-08-17
WO2003063864A2 (fr) 2003-08-07
PT2279737E (pt) 2013-02-01
NZ533936A (en) 2007-05-31
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US7612087B2 (en) 2009-11-03
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CO5601014A2 (es) 2006-01-31
CN100482225C (zh) 2009-04-29
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PL220725B1 (pl) 2015-12-31
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US20100048528A1 (en) 2010-02-25
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