CR11482A - Derivados de 1,2,3-triazol para uso como inhibidores de estearoil-coenzima a desaturasa - Google Patents
Derivados de 1,2,3-triazol para uso como inhibidores de estearoil-coenzima a desaturasaInfo
- Publication number
- CR11482A CR11482A CR11482A CR11482A CR11482A CR 11482 A CR11482 A CR 11482A CR 11482 A CR11482 A CR 11482A CR 11482 A CR11482 A CR 11482A CR 11482 A CR11482 A CR 11482A
- Authority
- CR
- Costa Rica
- Prior art keywords
- desaturasa
- coenzima
- estearoil
- inhibitors
- triazol derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
La presente invencion se refiere a compuestos de traizol sustituidos de la formula (I) y sales farmaceuticamente aceptables de los mismos, a composiciones farmaceuticas que los contienen y a su uso en medicina; en particular, la invencion se refiere a compuestos para modular la actividad de SCD.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0722077.5A GB0722077D0 (en) | 2007-11-09 | 2007-11-09 | Compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
CR11482A true CR11482A (es) | 2010-07-09 |
Family
ID=38858481
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR11482A CR11482A (es) | 2007-11-09 | 2010-06-09 | Derivados de 1,2,3-triazol para uso como inhibidores de estearoil-coenzima a desaturasa |
Country Status (32)
Country | Link |
---|---|
US (2) | US8486977B2 (es) |
EP (2) | EP2207770B1 (es) |
JP (1) | JP5491407B2 (es) |
KR (1) | KR101577080B1 (es) |
CN (1) | CN101918376B (es) |
AT (1) | ATE512140T1 (es) |
AU (1) | AU2008324172B2 (es) |
BR (1) | BRPI0820471A2 (es) |
CA (1) | CA2705113C (es) |
CO (1) | CO6270331A2 (es) |
CR (1) | CR11482A (es) |
CY (2) | CY1112233T1 (es) |
DK (2) | DK2207770T3 (es) |
DO (1) | DOP2010000137A (es) |
EA (1) | EA016621B1 (es) |
ES (2) | ES2457521T3 (es) |
GB (1) | GB0722077D0 (es) |
HK (2) | HK1141528A1 (es) |
HR (2) | HRP20110552T1 (es) |
IL (1) | IL205152A (es) |
MA (1) | MA31801B1 (es) |
ME (1) | ME01962B (es) |
MX (1) | MX2010005187A (es) |
MY (1) | MY163126A (es) |
NZ (1) | NZ584725A (es) |
PL (2) | PL2368887T3 (es) |
PT (2) | PT2207770E (es) |
RS (2) | RS51918B (es) |
SI (2) | SI2207770T1 (es) |
UA (1) | UA107324C2 (es) |
WO (1) | WO2009060053A1 (es) |
ZA (1) | ZA201002596B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0722077D0 (en) * | 2007-11-09 | 2007-12-19 | Smithkline Beecham Corp | Compounds |
GB0722075D0 (en) | 2007-11-09 | 2007-12-19 | Smithkline Beecham Corp | Compounds |
JP5529121B2 (ja) * | 2008-09-15 | 2014-06-25 | ダイキン工業株式会社 | 水性重合体分散組成物および表面処理剤 |
MX2011004125A (es) * | 2008-10-21 | 2011-05-19 | Metabolex Inc | Agonistas del receptor gpr120 de arilo y usos de los mismos. |
FR2974089B1 (fr) * | 2011-04-18 | 2014-04-25 | Univ Nice Sophia Antipolis | Derives de l'acadesine, produits et compositions les comprenant, leurs utilisations therapeutiques et leurs procedes de synthese. |
WO2013134546A1 (en) | 2012-03-07 | 2013-09-12 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
KR101676208B1 (ko) * | 2012-09-17 | 2016-11-14 | 에프. 호프만-라 로슈 아게 | 트라이아졸 카복스아미드 유도체 |
IL227890A0 (en) * | 2013-08-08 | 2014-01-30 | Galderm Therapeutics Ltd | Antiaging compounds containing bile acid and fatty acid conjugates |
AU2016211292B2 (en) * | 2015-01-30 | 2020-05-07 | Neurocrine Biosciences, Inc. | Substituted triazoles and methods relating thereto |
KR20180036318A (ko) * | 2016-09-30 | 2018-04-09 | 경북대학교 산학협력단 | 2-아미노-2-(1-도데실-1h-1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체를 유효성분으로 포함하는 퇴행성 신경질환 및 우울증 예방 또는 치료용 약학적 조성물 |
WO2018081167A1 (en) | 2016-10-24 | 2018-05-03 | Yumanity Therapeutics | Compounds and uses thereof |
WO2018129403A1 (en) * | 2017-01-06 | 2018-07-12 | Yumanity Therapeutics | Methods for the treatment of neurological disorders |
KR102292989B1 (ko) | 2017-03-29 | 2021-08-26 | 재단법인 아산사회복지재단 | S1pr4를 타겟으로 하는 비알코올성 지방간염 예방 또는 치료용 조성물 |
CA3083000A1 (en) | 2017-10-24 | 2019-05-02 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
JP2021522253A (ja) * | 2018-04-25 | 2021-08-30 | ユマニティ セラピューティクス,インコーポレーテッド | 化合物及びその使用 |
KR102017324B1 (ko) * | 2018-04-30 | 2019-09-02 | 경북대학교 산학협력단 | 신규한 asm 활성 직접 억제 화합물 2-아미노-2-(1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도 |
CA3127791A1 (en) | 2019-01-24 | 2020-07-30 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
CN114656414B (zh) * | 2022-05-24 | 2022-08-23 | 常熟华虞环境科技有限公司 | 三氮唑改性二氧化钛光催化剂及其制备方法 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4722941A (en) | 1978-06-07 | 1988-02-02 | Kali-Chemie Pharma Gmbh | Readily absorbable pharmaceutical compositions of per se poorly absorbable pharmacologically active agents and preparation thereof |
US4460372A (en) | 1981-02-17 | 1984-07-17 | Alza Corporation | Percutaneous absorption enhancer dispenser for use in coadministering drug and percutaneous absorption enhancer |
US4573996A (en) | 1984-01-03 | 1986-03-04 | Jonergin, Inc. | Device for the administration of an active agent to the skin or mucosa |
US4624665A (en) | 1984-10-01 | 1986-11-25 | Biotek, Inc. | Method of transdermal drug delivery |
US5223261A (en) | 1988-02-26 | 1993-06-29 | Riker Laboratories, Inc. | Transdermal estradiol delivery system |
US20070087363A1 (en) | 1998-12-22 | 2007-04-19 | Myriad Genetics, Incorporated | Therapeutic methods, compounds and compositions |
AU2001247228B2 (en) | 2000-02-24 | 2007-01-18 | Wisconsin Alumni Research Foundation | Stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents |
US7232662B2 (en) | 2000-09-26 | 2007-06-19 | Xenon Pharmaceuticals Inc. | Methods and compositions employing a novel stearoyl-CoA desaturase-hSCD5 |
MY141559A (en) * | 2002-04-26 | 2010-05-14 | Lilly Co Eli | Triazole derivatives as tachykinin receptor antagonists |
WO2005000821A1 (en) * | 2003-06-12 | 2005-01-06 | Eli Lilly And Company | Tachykinin receptor antagonists |
BRPI0412348A (pt) | 2003-07-30 | 2006-09-05 | Xenon Pharmaceuticals Inc | derivados de piperazina e seu uso como agentes terapêuticos |
JP4831577B2 (ja) | 2003-07-30 | 2011-12-07 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | ピリダジン誘導体および治療剤としての用途 |
WO2007046867A2 (en) | 2005-05-19 | 2007-04-26 | Xenon Pharmaceuticals Inc. | Piperidine derivatives and their uses as therapeutic agents |
WO2007046868A2 (en) | 2005-05-19 | 2007-04-26 | Xenon Pharmaceuticals Inc. | Thiazolidine derivatives and their uses as therapeutic agents |
WO2008073461A2 (en) * | 2006-12-11 | 2008-06-19 | Wyeth | Ion channel modulators |
GB0625654D0 (en) * | 2006-12-21 | 2007-01-31 | Smithkline Beecham Corp | Compounds |
GB0625604D0 (en) * | 2006-12-21 | 2007-01-31 | Smithkline Beecham Corp | Compounds |
GB0625605D0 (en) * | 2006-12-21 | 2007-01-31 | Smithkline Beecham Corp | Compounds |
WO2008104524A1 (en) * | 2007-02-28 | 2008-09-04 | Smithkline Beecham Corporation | Thiadiazole derivatives, inhibitors of stearoyl-coa desaturase |
EP2148868A1 (en) * | 2007-05-15 | 2010-02-03 | NeuroSearch A/S | Novel aromatic heterocyclic carboxylic acid amide derivatives useful as potassium channel modulators |
GB0714129D0 (en) | 2007-07-19 | 2007-08-29 | Smithkline Beecham Corp | compounds |
GB0715055D0 (en) | 2007-08-02 | 2007-09-12 | Smithkline Beecham Corp | Compounds |
GB0721419D0 (en) | 2007-10-31 | 2007-12-12 | Smithkline Beecham Corp | Compounds |
GB0722075D0 (en) * | 2007-11-09 | 2007-12-19 | Smithkline Beecham Corp | Compounds |
GB0722077D0 (en) * | 2007-11-09 | 2007-12-19 | Smithkline Beecham Corp | Compounds |
GB0810913D0 (en) | 2008-06-13 | 2008-07-23 | Smithkline Beecham Corp | Comppounds |
-
2007
- 2007-11-09 GB GBGB0722077.5A patent/GB0722077D0/en not_active Ceased
-
2008
- 2008-07-11 UA UAA201007152A patent/UA107324C2/ru unknown
- 2008-11-07 ES ES11168642.4T patent/ES2457521T3/es active Active
- 2008-11-07 ME MEP-2011-369A patent/ME01962B/me unknown
- 2008-11-07 WO PCT/EP2008/065104 patent/WO2009060053A1/en active Application Filing
- 2008-11-07 RS RS20110369A patent/RS51918B/en unknown
- 2008-11-07 SI SI200830349T patent/SI2207770T1/sl unknown
- 2008-11-07 RS RS20140219A patent/RS53294B/en unknown
- 2008-11-07 NZ NZ584725A patent/NZ584725A/en not_active IP Right Cessation
- 2008-11-07 JP JP2010532598A patent/JP5491407B2/ja not_active Expired - Fee Related
- 2008-11-07 PT PT08846247T patent/PT2207770E/pt unknown
- 2008-11-07 PL PL11168642T patent/PL2368887T3/pl unknown
- 2008-11-07 DK DK08846247.8T patent/DK2207770T3/da active
- 2008-11-07 EP EP08846247A patent/EP2207770B1/en active Active
- 2008-11-07 CA CA2705113A patent/CA2705113C/en not_active Expired - Fee Related
- 2008-11-07 ES ES08846247T patent/ES2366422T3/es active Active
- 2008-11-07 EA EA201070588A patent/EA016621B1/ru not_active IP Right Cessation
- 2008-11-07 MY MYPI2010002145A patent/MY163126A/en unknown
- 2008-11-07 PT PT111686424T patent/PT2368887E/pt unknown
- 2008-11-07 DK DK11168642.4T patent/DK2368887T3/da active
- 2008-11-07 US US12/741,637 patent/US8486977B2/en not_active Expired - Fee Related
- 2008-11-07 MX MX2010005187A patent/MX2010005187A/es active IP Right Grant
- 2008-11-07 KR KR1020107012597A patent/KR101577080B1/ko active IP Right Grant
- 2008-11-07 BR BRPI0820471-3A patent/BRPI0820471A2/pt not_active Application Discontinuation
- 2008-11-07 SI SI200831183T patent/SI2368887T1/sl unknown
- 2008-11-07 CN CN2008801245066A patent/CN101918376B/zh not_active Expired - Fee Related
- 2008-11-07 PL PL08846247T patent/PL2207770T3/pl unknown
- 2008-11-07 AT AT08846247T patent/ATE512140T1/de active
- 2008-11-07 EP EP11168642.4A patent/EP2368887B8/en active Active
- 2008-11-07 AU AU2008324172A patent/AU2008324172B2/en not_active Ceased
-
2010
- 2010-04-14 ZA ZA2010/02596A patent/ZA201002596B/en unknown
- 2010-04-15 IL IL205152A patent/IL205152A/en active IP Right Grant
- 2010-04-30 MA MA32807A patent/MA31801B1/fr unknown
- 2010-05-06 CO CO10054279A patent/CO6270331A2/es active IP Right Grant
- 2010-05-07 DO DO2010000137A patent/DOP2010000137A/es unknown
- 2010-06-09 CR CR11482A patent/CR11482A/es unknown
- 2010-08-20 HK HK10108014.3A patent/HK1141528A1/xx not_active IP Right Cessation
-
2011
- 2011-07-25 HR HR20110552T patent/HRP20110552T1/hr unknown
- 2011-08-26 CY CY20111100816T patent/CY1112233T1/el unknown
-
2012
- 2012-02-02 HK HK12100960.2A patent/HK1160467A1/xx not_active IP Right Cessation
-
2013
- 2013-06-21 US US13/923,420 patent/US9051281B2/en not_active Expired - Fee Related
-
2014
- 2014-04-11 HR HRP20140346AT patent/HRP20140346T1/hr unknown
- 2014-05-09 CY CY20141100328T patent/CY1115058T1/el unknown
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