BR0315106A - Derivados antimicrobianos de [3.1.0]oxazolidinona bicìclica - Google Patents
Derivados antimicrobianos de [3.1.0]oxazolidinona bicìclicaInfo
- Publication number
- BR0315106A BR0315106A BR0315106-9A BR0315106A BR0315106A BR 0315106 A BR0315106 A BR 0315106A BR 0315106 A BR0315106 A BR 0315106A BR 0315106 A BR0315106 A BR 0315106A
- Authority
- BR
- Brazil
- Prior art keywords
- oxazolidinone
- derivatives
- bicyclic
- processes
- antimicrobial derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
"DERIVADOS ANTIMICROBIANOS DE [3.1.0]OXAZOLIDINONA BICìCLICA". A presente invenção refere-se a determinados derivados de [3.1.O]oxazolidinona bicíclica das fórmulas I e II, descritas aqui, ou sais farmaceuticamente aceitáveis ou pró-drogas dos mesmos, que são agentes antibacterianos, composições farmacêuticas contendo os mesmos, processos para seu uso e processos para preparação desses compostos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41773502P | 2002-10-09 | 2002-10-09 | |
PCT/US2003/028560 WO2004033451A1 (en) | 2002-10-09 | 2003-10-03 | Antimicrobial [3.1.0] bicyclic oxazolidinone derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0315106A true BR0315106A (pt) | 2005-08-09 |
Family
ID=32094075
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0315106-9A BR0315106A (pt) | 2002-10-09 | 2003-10-03 | Derivados antimicrobianos de [3.1.0]oxazolidinona bicìclica |
Country Status (10)
Country | Link |
---|---|
US (1) | US6875784B2 (pt) |
EP (1) | EP1549641A1 (pt) |
JP (1) | JP2006508934A (pt) |
AR (1) | AR041568A1 (pt) |
AU (1) | AU2003278791A1 (pt) |
BR (1) | BR0315106A (pt) |
CA (1) | CA2501352A1 (pt) |
MX (1) | MXPA05003780A (pt) |
TW (1) | TW200410961A (pt) |
WO (1) | WO2004033451A1 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2530140C (en) | 2003-07-02 | 2010-11-09 | Merck & Co., Inc. | Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof |
EP1646630A1 (en) * | 2003-07-02 | 2006-04-19 | Merck & Co., Inc. | Oxazolidinone antibiotics and derivatives thereof |
KR20090096716A (ko) * | 2007-01-09 | 2009-09-14 | 바이엘 쉐링 파마 악티엔게젤샤프트 | 아지리딘의 플루오르화에 의한 방사성표지 |
EP1944288A1 (en) * | 2007-01-09 | 2008-07-16 | Bayer Schering Pharma Aktiengesellschaft | Radiolabelling via fluorination of aziridines |
NZ586104A (en) | 2007-12-20 | 2012-02-24 | Astrazeneca Ab | Carbamoyl compounds as dgat1 inhibitors 190 |
WO2009090548A2 (en) * | 2008-01-17 | 2009-07-23 | Glenmark Pharmaceuticals, S.A. | 3-azabicyclo [3.1.0] hexane derivatives as vanilloid receptor ligands |
CA2743971A1 (en) | 2008-11-20 | 2010-05-27 | Panacea Biotec Ltd. | Novel antimicrobials |
BR112012000657A2 (pt) | 2009-06-26 | 2016-11-16 | Panacea Biotec Ltd | novos azabicilohexanos |
BR112013007566A2 (pt) | 2010-09-28 | 2016-08-02 | Panacea Biotec Ltd | novos compostos bicíclicos |
SI3143011T1 (sl) | 2014-05-13 | 2021-08-31 | F. Hoffmann-La Roche Ag | Devterirane heterociklične spojine in njihova uporaba kot kontrastna sredstva |
KR102511898B1 (ko) * | 2015-07-17 | 2023-03-20 | 더 글로벌 얼라이언스 포 티비 드러그 디벨롭먼트, 잉크. | 항미생물 요법을 위한 치환된 페닐옥사졸리디논 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4183857A (en) | 1978-07-06 | 1980-01-15 | Shell Oil Company | 3-Benzyl-3-azabicyclo(3.1.0)hexane-2,4-dione |
US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US5011472A (en) | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
US5023472A (en) * | 1988-09-09 | 1991-06-11 | Texas Instruments Incorporated | Capacitor-driven signal transmission circuit |
SK283420B6 (sk) | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
KR960004339A (ko) | 1994-07-02 | 1996-02-23 | 임성기 | 신규한 퀴놀린계 화합물 및 그 의 제조방법 |
ATE239720T1 (de) | 1995-02-02 | 2003-05-15 | Daiichi Seiyaku Co | Heterozyklische verbindungen |
US6124334A (en) * | 1995-02-03 | 2000-09-26 | Pharmacia & Upjohn Company | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials |
US6255304B1 (en) * | 1997-05-30 | 2001-07-03 | Pharmacia & Upjohn Company | Oxazolidinone antibacterial agents having a thiocarbonyl functionality |
EP0984947B8 (en) | 1997-05-30 | 2005-06-15 | Pharmacia & Upjohn Company LLC | Oxazolidinone antibacterial agents having a thiocarbonyl functionality |
US6069141A (en) | 1998-02-13 | 2000-05-30 | Pharmacia & Upjohn Company | Substituted aminophenyl isoxazoline derivatives useful as antimicrobials |
CN1311787A (zh) | 1998-06-05 | 2001-09-05 | 阿斯特拉曾尼卡有限公司 | 噁唑烷酮衍生物、其制备方法以及含有它们的药物组合物 |
TW572757B (en) | 1998-08-24 | 2004-01-21 | Bristol Myers Squibb Co | Novel isoxazolinone antibacterial agents |
GB9821938D0 (en) | 1998-10-09 | 1998-12-02 | Zeneca Ltd | Chemical compounds |
HUP0203869A2 (hu) | 1999-12-21 | 2003-07-28 | Pharmacia & Upjohn Co. | Szulfoximin funkcionalitással rendelkező oxazolidinok és alkalmazásuk mikrobaellenes szerként, a vegyületeket tartalmazó gyógyszerkészítmények |
US6451345B1 (en) * | 2000-01-20 | 2002-09-17 | Eurand Pharmaceuticals Ltd. | Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration |
US6642238B2 (en) * | 2000-02-10 | 2003-11-04 | Pharmacia And Upjohn Company | Oxazolidinone thioamides with piperazine amide substituents |
GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
PE20020044A1 (es) * | 2000-06-16 | 2002-01-30 | Upjohn Co | Tiazina oxazolidinona |
PL363960A1 (en) | 2000-07-17 | 2004-11-29 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
ATE321024T1 (de) | 2000-10-17 | 2006-04-15 | Pharmacia & Upjohn Co Llc | Verfahren zur herstellung von oxazolidinonverbindungen |
CA2424402A1 (en) * | 2000-12-21 | 2002-08-01 | Pharmacia & Upjohn Company | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections |
CA2443410A1 (en) | 2001-04-17 | 2003-04-03 | Yasumichi Fukuda | Bicyclo[3,1,0]hexane containing oxazolidinone antibiotic and derivatives thereof |
WO2004014392A1 (en) * | 2002-07-29 | 2004-02-19 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
-
2003
- 2003-10-02 US US10/677,451 patent/US6875784B2/en not_active Expired - Fee Related
- 2003-10-03 EP EP03770310A patent/EP1549641A1/en not_active Withdrawn
- 2003-10-03 BR BR0315106-9A patent/BR0315106A/pt not_active IP Right Cessation
- 2003-10-03 CA CA002501352A patent/CA2501352A1/en not_active Abandoned
- 2003-10-03 JP JP2004543288A patent/JP2006508934A/ja not_active Withdrawn
- 2003-10-03 MX MXPA05003780A patent/MXPA05003780A/es unknown
- 2003-10-03 WO PCT/US2003/028560 patent/WO2004033451A1/en active Application Filing
- 2003-10-03 AU AU2003278791A patent/AU2003278791A1/en not_active Abandoned
- 2003-10-09 TW TW092128102A patent/TW200410961A/zh unknown
- 2003-10-09 AR ARP030103679A patent/AR041568A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
AR041568A1 (es) | 2005-05-18 |
CA2501352A1 (en) | 2004-04-22 |
MXPA05003780A (es) | 2005-06-08 |
EP1549641A1 (en) | 2005-07-06 |
WO2004033451A1 (en) | 2004-04-22 |
US20040127530A1 (en) | 2004-07-01 |
TW200410961A (en) | 2004-07-01 |
AU2003278791A1 (en) | 2004-05-04 |
US6875784B2 (en) | 2005-04-05 |
JP2006508934A (ja) | 2006-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2073 DE 28/09/2010. |