BRPI0210707B8 - composição de solução para administração tópica no tratamento de distúrbios alérgicos ou inflamatórios do olho e do nariz e seu método de preparação - Google Patents
composição de solução para administração tópica no tratamento de distúrbios alérgicos ou inflamatórios do olho e do nariz e seu método de preparaçãoInfo
- Publication number
- BRPI0210707B8 BRPI0210707B8 BRPI0210707A BR0210707A BRPI0210707B8 BR PI0210707 B8 BRPI0210707 B8 BR PI0210707B8 BR PI0210707 A BRPI0210707 A BR PI0210707A BR 0210707 A BR0210707 A BR 0210707A BR PI0210707 B8 BRPI0210707 B8 BR PI0210707B8
- Authority
- BR
- Brazil
- Prior art keywords
- nose
- eye
- inflammatory disorders
- topical administration
- allergic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30131501P | 2001-06-27 | 2001-06-27 | |
| PCT/US2002/019417 WO2003002093A1 (en) | 2001-06-27 | 2002-06-19 | Olopatadine formulations for topical administration |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR0210707A BR0210707A (pt) | 2004-07-20 |
| BRPI0210707B1 BRPI0210707B1 (pt) | 2015-08-04 |
| BRPI0210707B8 true BRPI0210707B8 (pt) | 2021-05-25 |
Family
ID=23162841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0210707A BRPI0210707B8 (pt) | 2001-06-27 | 2002-06-19 | composição de solução para administração tópica no tratamento de distúrbios alérgicos ou inflamatórios do olho e do nariz e seu método de preparação |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US6995186B2 (enExample) |
| EP (1) | EP1399127B1 (enExample) |
| JP (5) | JP4827374B2 (enExample) |
| KR (1) | KR100884711B1 (enExample) |
| CN (1) | CN1211125C (enExample) |
| AR (1) | AR034619A1 (enExample) |
| AT (1) | ATE295149T1 (enExample) |
| AU (1) | AU2002310461B2 (enExample) |
| BR (1) | BRPI0210707B8 (enExample) |
| CA (1) | CA2447924C (enExample) |
| DE (1) | DE60204142T2 (enExample) |
| DK (1) | DK1399127T3 (enExample) |
| ES (1) | ES2238574T3 (enExample) |
| GC (1) | GC0000397A (enExample) |
| MX (1) | MXPA03011947A (enExample) |
| PL (1) | PL205565B1 (enExample) |
| PT (1) | PT1399127E (enExample) |
| TW (1) | TWI231759B (enExample) |
| WO (1) | WO2003002093A1 (enExample) |
| ZA (1) | ZA200308771B (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100055152A1 (en) * | 2008-08-26 | 2010-03-04 | Trutek Corporation | Antihistamine and antihistamine-like nasal application, products, and method |
| US7977376B2 (en) | 2001-06-27 | 2011-07-12 | Novartis Ag | Olopatadine formulations for topical nasal administration |
| TWI231759B (en) * | 2001-06-27 | 2005-05-01 | Alcon Inc | Olopatadine formulations for topical administration |
| US20050209312A1 (en) * | 2004-03-19 | 2005-09-22 | Bausch & Lomb Incorporated | Carboxylic acid derivatives of doxepin formulations preserved with low-irritation preservative |
| CN1942173B (zh) * | 2004-04-08 | 2012-05-09 | 协和发酵麒麟株式会社 | 稳定性提高的固体制剂及其制造方法 |
| EP1757285A4 (en) * | 2004-04-21 | 2007-11-07 | Kyowa Hakko Kogyo Kk | MEANS FOR THE PREVENTION AND / OR TREATMENT OF CHRONIC SINUSITIS |
| AU2005259911A1 (en) * | 2004-06-28 | 2006-01-12 | Alcon, Inc. | Topical formulations for treating allergic diseases |
| PL1814538T3 (pl) * | 2004-11-24 | 2010-02-26 | Alcon Inc | Sposób dostarczania donosowego sprayu |
| WO2006097458A1 (en) * | 2005-03-15 | 2006-09-21 | Nycomed Gmbh | Novel combination |
| EP1901708B1 (en) | 2005-07-08 | 2013-09-11 | Senju Pharmaceutical Co., Ltd. | Percutaneously absorptive ophthalmic preparation comprising olopatadine |
| US20070077302A1 (en) * | 2005-09-30 | 2007-04-05 | Azaam Alli | Methods for stabilizing ophthalmic compositions |
| US20080114076A1 (en) * | 2006-11-09 | 2008-05-15 | Alcon Manufacturing Ltd. | Punctal plug comprising a water-insoluble polymeric matrix |
| JP5411703B2 (ja) * | 2006-11-09 | 2014-02-12 | アルコン リサーチ, リミテッド | 薬物送達のための水不溶性ポリマーマトリクス |
| CA2670944A1 (en) * | 2006-12-18 | 2008-06-26 | Alcon Research, Ltd. | Devices and methods for ophthalmic drug delivery |
| WO2008093358A2 (en) * | 2007-01-29 | 2008-08-07 | Sun Pharmaceutical Industries Limited | Aqueous topical solution containing olopatadine |
| WO2008097220A1 (en) * | 2007-02-07 | 2008-08-14 | Alcon, Inc. | Olopatadine formulations for topical nasal administration |
| WO2008120249A1 (en) * | 2007-03-30 | 2008-10-09 | Sifi S.P.A. | Pharmaceutical formulations based on apolar and polar lipids for ophthalmic use |
| CA2682730A1 (en) * | 2007-04-11 | 2008-10-23 | Alcon Research, Ltd. | Use of an inhibitor of tnf.alpha. plus an antihistamine to treat allergic rhinitis and allergic conjunctivitis |
| EP2189157A4 (en) * | 2007-09-06 | 2012-10-31 | Kyowa Hakko Kirin Co Ltd | EYE DROPPING WITH DIBENZO [b, e] OXEPINE DERIVATIVE |
| JP2011520963A (ja) * | 2008-05-19 | 2011-07-21 | アルコン リサーチ, リミテッド | カルボキシビニルポリマーおよびポビドンポリマーを有する医薬組成物 |
| AU2009288566A1 (en) * | 2008-08-26 | 2010-03-11 | Trutek Corp. | Electrostatically charged mask filter products and method for increased filtration efficiency |
| JP2012509250A (ja) * | 2008-08-28 | 2012-04-19 | トルテック コーポレーション | 抗ヒスタミン及び抗ヒスタミン様経鼻適用製品及び方法 |
| US9458198B1 (en) | 2009-06-26 | 2016-10-04 | Shire Orphan Therapies Gmbh | Cyclic peptide-based NPR-B agonists |
| BR112012001169A2 (pt) * | 2009-07-17 | 2016-03-01 | Alcon Res Ltd | sistema de pulverização nasal de olopatadina para crianças |
| WO2011027322A1 (en) * | 2009-09-03 | 2011-03-10 | Ranbaxy Laboratories Limited | Extended release dosage form containing olopatadine for oral administration |
| PH12012500562A1 (en) | 2009-09-25 | 2012-10-22 | Takeda Pharmaceuticals Co | Novel npr-b antagonists |
| US8551938B2 (en) * | 2009-09-25 | 2013-10-08 | Alcon Research, Ltd. | NPR-B agonists |
| US20110082145A1 (en) * | 2009-10-01 | 2011-04-07 | Alcon Research, Ltd. | Olopatadine compositions and uses thereof |
| WO2011075471A2 (en) | 2009-12-18 | 2011-06-23 | Alcon Research, Ltd. | Novel npr-b agonists and methods of use for the treatment of c-type natriuretic peptide-mediated disorders |
| TW201121995A (en) | 2009-12-18 | 2011-07-01 | Alcon Res Ltd | Novel NPR-B agonists |
| EP2595603A1 (en) * | 2010-07-21 | 2013-05-29 | Alcon Research, Ltd. | Pharmaceutical composition with enhanced solubility characteristics |
| CN104758921A (zh) * | 2010-11-08 | 2015-07-08 | 希尔洛有限公司 | 缓冲的眼用组合物以及使用其的方法 |
| TWI544922B (zh) * | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | 高濃度歐羅派特錠(olopatadine)眼用組成物 |
| CN102885767A (zh) * | 2012-11-02 | 2013-01-23 | 江苏吉贝尔药业有限公司 | 一种新的盐酸奥洛他定滴眼液及其制备方法 |
| EP3576770A1 (en) | 2017-02-01 | 2019-12-11 | Shire Human Genetic Therapies, Inc. | Compounds and compositions for the treatment of ophthalmic disorders |
| JP7037349B2 (ja) * | 2017-06-23 | 2022-03-16 | 参天製薬株式会社 | 水溶性粘稠化剤を含有する医薬組成物 |
| WO2018235935A1 (ja) * | 2017-06-23 | 2018-12-27 | 参天製薬株式会社 | 水溶性粘稠化剤を含有する医薬組成物 |
| US20230018472A1 (en) * | 2019-12-06 | 2023-01-19 | Toko Yakuhin Kogyo Co., Ltd. | Rhinenchysis composition containing olopatadine |
| EP4129341A4 (en) * | 2020-03-31 | 2024-04-24 | Santen Pharmaceutical Co., Ltd. | SILVER SALT-CONTAINING OPHTHALMIC AQUEOUS COMPOSITION WITH FILLED RESIN CONTAINER |
| CN111700860A (zh) * | 2020-07-09 | 2020-09-25 | 浙江尖峰药业有限公司 | 盐酸奥洛他定滴眼液及其制备方法 |
| WO2023054669A1 (ja) * | 2021-09-30 | 2023-04-06 | ロート製薬株式会社 | 眼科組成物 |
| CN119318630B (zh) * | 2024-10-16 | 2025-08-22 | 苏州欧康维视生物科技有限公司 | 一种阿托品药物组合物 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4370324A (en) | 1980-09-17 | 1983-01-25 | Bernstein Joel E | Method and composition for treating and preventing irritation of the eyes |
| US4407791A (en) | 1981-09-28 | 1983-10-04 | Alcon Laboratories, Inc. | Ophthalmic solutions |
| US4749700A (en) * | 1984-10-23 | 1988-06-07 | Nastech Pharmaceutical Co, Inc. | Novel methods of administering antihistamines, antinausea and antiemetic pharmaceutical agents and novel dosage forms containing same |
| GB8520662D0 (en) * | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| US4923892A (en) * | 1985-08-17 | 1990-05-08 | Burroughs Wellcome Co. | Tricyclic aromatic compounds |
| JPS6310784A (ja) | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
| ATE84968T1 (de) * | 1987-11-13 | 1993-02-15 | Asta Medica Ag | Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge. |
| IT1250691B (it) * | 1991-07-22 | 1995-04-21 | Giancarlo Santus | Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac. |
| JP3662944B2 (ja) | 1993-08-24 | 2005-06-22 | 協和醗酵工業株式会社 | 点鼻剤 |
| US5897858A (en) * | 1994-02-03 | 1999-04-27 | Schering-Plough Healthcare Products, Inc. | Nasal spray compositions exhibiting increased retention in the nasal cavity |
| US5641805A (en) | 1995-06-06 | 1997-06-24 | Alcon Laboratories, Inc. | Topical ophthalmic formulations for treating allergic eye diseases |
| US6207684B1 (en) * | 1997-06-09 | 2001-03-27 | Bridge Pharma, Inc. | Compounds with combined antihistaminic and mast cell stabilizing activities, intended for ophthalmic use |
| PT1037627E (pt) | 1998-07-14 | 2001-11-30 | Alcon Lab Inc | Utilizacao do acido 11-(3-dimetilaminopropilideno)-6,11-dihidrodibenz¬b,e|oxepin-2-acetico e seus sais derivados farmaceuticamente aceitaveis para a producao de um medicamento para o tratamento de doencas inflamatorias oftalmicas nao-alergicas e para a prebencao da neovascularizacao ocular |
| US6146622A (en) * | 1998-10-27 | 2000-11-14 | Alcon Laboratories, Inc. | Use of certain anionic amino acid based surfactants to enhance antimicrobial effectiveness of topically administrable pharmaceutical compositions |
| BR9914799A (pt) * | 1998-10-27 | 2001-07-10 | Alcon Lab Inc | Sistema conservante para composições farmacêuticas administráveis topicamente contendo um sabão de ácido graxo/aminoácido |
| US6274626B1 (en) * | 1998-12-22 | 2001-08-14 | Bausch & Lomb Incorporated | Pheniramine-containing compositions and method for treating allergic responses |
| US6174914B1 (en) * | 1999-06-15 | 2001-01-16 | Alcon Laboratories, Inc. | Method of inhibiting cytokine release from human ocular cells |
| CN1374874A (zh) | 1999-09-21 | 2002-10-16 | 爱尔康实验室公司 | 使用脂肪酸/氨基酸皂类提高局部药物组合物的抗菌效力 |
| CN1376066A (zh) | 1999-11-18 | 2002-10-23 | 爱尔康公司 | H1拮抗剂和安全类固醇的治疗眼病的用途 |
| WO2001054687A1 (en) | 2000-01-25 | 2001-08-02 | Alcon Universal Ltd. | Ophthalmic anti-allergy compositions suitable for use with contact lenses |
| AR031135A1 (es) | 2000-10-10 | 2003-09-10 | Upjohn Co | Composiciones de antibiotico topico para el tratamiento de infecciones oculares |
| TWI231759B (en) * | 2001-06-27 | 2005-05-01 | Alcon Inc | Olopatadine formulations for topical administration |
| CA2504200A1 (en) | 2002-11-12 | 2004-05-27 | Alcon, Inc. | The use of an anti-allergy agent and a steroid to treat allergic rhinitis |
-
2002
- 2002-06-18 TW TW091113234A patent/TWI231759B/zh not_active IP Right Cessation
- 2002-06-19 BR BRPI0210707A patent/BRPI0210707B8/pt not_active IP Right Cessation
- 2002-06-19 CN CNB028120434A patent/CN1211125C/zh not_active Expired - Lifetime
- 2002-06-19 AT AT02737539T patent/ATE295149T1/de active
- 2002-06-19 DK DK02737539T patent/DK1399127T3/da active
- 2002-06-19 EP EP02737539A patent/EP1399127B1/en not_active Expired - Lifetime
- 2002-06-19 JP JP2003508332A patent/JP4827374B2/ja not_active Expired - Lifetime
- 2002-06-19 PT PT02737539T patent/PT1399127E/pt unknown
- 2002-06-19 PL PL367780A patent/PL205565B1/pl unknown
- 2002-06-19 US US10/175,106 patent/US6995186B2/en not_active Expired - Lifetime
- 2002-06-19 DE DE60204142T patent/DE60204142T2/de not_active Expired - Lifetime
- 2002-06-19 KR KR1020037014821A patent/KR100884711B1/ko not_active Expired - Lifetime
- 2002-06-19 AU AU2002310461A patent/AU2002310461B2/en not_active Expired
- 2002-06-19 CA CA002447924A patent/CA2447924C/en not_active Expired - Lifetime
- 2002-06-19 WO PCT/US2002/019417 patent/WO2003002093A1/en not_active Ceased
- 2002-06-19 MX MXPA03011947A patent/MXPA03011947A/es active IP Right Grant
- 2002-06-19 ES ES02737539T patent/ES2238574T3/es not_active Expired - Lifetime
- 2002-06-22 GC GCP20022092 patent/GC0000397A/en active
- 2002-06-24 AR ARP020102365A patent/AR034619A1/es not_active Application Discontinuation
-
2003
- 2003-11-11 ZA ZA2003/08771A patent/ZA200308771B/en unknown
-
2005
- 2005-03-15 US US11/079,996 patent/US7402609B2/en not_active Expired - Lifetime
-
2009
- 2009-03-02 JP JP2009048628A patent/JP2009114213A/ja not_active Withdrawn
-
2010
- 2010-03-24 JP JP2010069010A patent/JP2010150292A/ja not_active Withdrawn
-
2012
- 2012-02-21 JP JP2012035170A patent/JP5328947B2/ja not_active Expired - Lifetime
-
2013
- 2013-03-25 JP JP2013061887A patent/JP2013127005A/ja not_active Withdrawn
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