CY1110644T1 - 5,6,7-τριυδροξυεπτανοϊκο οξυ και τα αναλογα για την θεραπεια οφθαλμικων ασθενειων που σχετιζονται με υπερεκφυτικες και αγγειογενεις αντιδρασεις - Google Patents
5,6,7-τριυδροξυεπτανοϊκο οξυ και τα αναλογα για την θεραπεια οφθαλμικων ασθενειων που σχετιζονται με υπερεκφυτικες και αγγειογενεις αντιδρασειςInfo
- Publication number
- CY1110644T1 CY1110644T1 CY20101100473T CY101100473T CY1110644T1 CY 1110644 T1 CY1110644 T1 CY 1110644T1 CY 20101100473 T CY20101100473 T CY 20101100473T CY 101100473 T CY101100473 T CY 101100473T CY 1110644 T1 CY1110644 T1 CY 1110644T1
- Authority
- CY
- Cyprus
- Prior art keywords
- hypercapillary
- analogues
- treatment
- diseases
- trihydroxyheptanoic acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Αναφέρονται συνθέσεις που περιέχουν 5,6,7-τριυδροξυεπτανοϊκό οξύ και τα ανάλογά του και οι χρήσεις τους για την θεραπεία παθήσεων του οπίσθιου τμήματος του οφθαλμού όπως και παθήσεων που χαρακτηρίζονται από κυτταρικό υπέρ πολλαπλασιασμό ή αγγειογέννηση.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62620904P | 2004-11-09 | 2004-11-09 | |
EP05824279A EP1809270B1 (en) | 2004-11-09 | 2005-11-08 | 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1110644T1 true CY1110644T1 (el) | 2015-04-29 |
Family
ID=35809550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20101100473T CY1110644T1 (el) | 2004-11-09 | 2010-05-28 | 5,6,7-τριυδροξυεπτανοϊκο οξυ και τα αναλογα για την θεραπεια οφθαλμικων ασθενειων που σχετιζονται με υπερεκφυτικες και αγγειογενεις αντιδρασεις |
Country Status (20)
Country | Link |
---|---|
US (2) | US7879905B2 (el) |
EP (1) | EP1809270B1 (el) |
JP (3) | JP2008519763A (el) |
KR (1) | KR101237534B1 (el) |
CN (1) | CN101052387A (el) |
AT (1) | ATE461696T1 (el) |
AU (1) | AU2005304733B2 (el) |
BR (1) | BRPI0517972A (el) |
CA (1) | CA2584286C (el) |
CY (1) | CY1110644T1 (el) |
DE (1) | DE602005020178D1 (el) |
DK (1) | DK1809270T3 (el) |
ES (1) | ES2340786T3 (el) |
HK (1) | HK1110768A1 (el) |
MX (1) | MX2007004622A (el) |
PL (1) | PL1809270T3 (el) |
PT (1) | PT1809270E (el) |
SI (1) | SI1809270T1 (el) |
WO (1) | WO2006052950A1 (el) |
ZA (1) | ZA200703992B (el) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7879905B2 (en) * | 2004-11-09 | 2011-02-01 | Alcon, Inc. | 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses |
US20060154981A1 (en) * | 2005-01-12 | 2006-07-13 | Alcon, Inc. | Method of reducing intraocular pressure and treating glaucoma |
US7687539B1 (en) | 2005-11-07 | 2010-03-30 | Alcon Research, Ltd. | Method of treating ocular allergy |
EP2079459A2 (en) * | 2006-11-07 | 2009-07-22 | Alcon Research, Ltd. | Method of treating asthma, allergic rhinitis, and skin disorders |
EA201290442A1 (ru) * | 2009-12-04 | 2012-11-30 | Юклид Системз Корпорэйшн | Композиция и способы профилактики и лечения макулярной дегенерации, диабетической ретинопатии и диабетического макулярного отека |
WO2011096941A1 (en) * | 2010-02-08 | 2011-08-11 | Alcon Research, Ltd. | Method of treating ocular allergy |
JP2013521230A (ja) * | 2010-02-25 | 2013-06-10 | アルコン リサーチ, リミテッド | 角膜創傷治癒を促進する方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4975537A (en) | 1985-10-23 | 1990-12-04 | The Upjohn Company | Δ9(11) -angiostatic steroids |
US4771042A (en) | 1985-11-25 | 1988-09-13 | The Upjohn Company | Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments |
JP2834512B2 (ja) * | 1990-01-30 | 1998-12-09 | 帝人株式会社 | リポキシン誘導体を有効成分とする疾患治療剤 |
US5441951A (en) | 1994-06-15 | 1995-08-15 | Brigham & Women's Hospital | Lipoxin compounds |
US6048897A (en) * | 1993-06-15 | 2000-04-11 | Brigham And Women's Hospital | Lipoxin compounds and their use in treating cell proliferative disorders |
JPH08268886A (ja) | 1995-03-31 | 1996-10-15 | Eisai Co Ltd | 血管新生抑制剤 |
US6645978B1 (en) * | 1999-11-09 | 2003-11-11 | Alcon, Inc. | Lipoxin A4 and its analogs for the treatment of dry eye |
AR030345A1 (es) | 2000-08-14 | 2003-08-20 | Alcon Inc | Metodo de tratamiento de desordenes relacionados con angiogenesis |
PT1406698E (pt) | 2001-03-02 | 2009-01-12 | Brigham & Womens Hospital | Análogos de lipoxina como novos inibidores da angiogénese |
MXPA06013170A (es) * | 2004-05-14 | 2007-02-13 | Alcon Inc | Metodo para tratar trastornos de queratoconjuntivitis seca y uveitis. |
US7879905B2 (en) * | 2004-11-09 | 2011-02-01 | Alcon, Inc. | 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses |
-
2005
- 2005-11-08 US US11/268,968 patent/US7879905B2/en not_active Expired - Fee Related
- 2005-11-08 KR KR1020077010194A patent/KR101237534B1/ko not_active IP Right Cessation
- 2005-11-08 BR BRPI0517972-6A patent/BRPI0517972A/pt not_active IP Right Cessation
- 2005-11-08 MX MX2007004622A patent/MX2007004622A/es active IP Right Grant
- 2005-11-08 ES ES05824279T patent/ES2340786T3/es active Active
- 2005-11-08 CA CA2584286A patent/CA2584286C/en not_active Expired - Fee Related
- 2005-11-08 AU AU2005304733A patent/AU2005304733B2/en not_active Ceased
- 2005-11-08 PL PL05824279T patent/PL1809270T3/pl unknown
- 2005-11-08 JP JP2007540158A patent/JP2008519763A/ja active Pending
- 2005-11-08 DK DK05824279.3T patent/DK1809270T3/da active
- 2005-11-08 PT PT05824279T patent/PT1809270E/pt unknown
- 2005-11-08 WO PCT/US2005/040392 patent/WO2006052950A1/en active Application Filing
- 2005-11-08 CN CNA200580037399XA patent/CN101052387A/zh active Pending
- 2005-11-08 AT AT05824279T patent/ATE461696T1/de active
- 2005-11-08 SI SI200530999T patent/SI1809270T1/sl unknown
- 2005-11-08 ZA ZA200703992A patent/ZA200703992B/xx unknown
- 2005-11-08 EP EP05824279A patent/EP1809270B1/en not_active Not-in-force
- 2005-11-08 DE DE602005020178T patent/DE602005020178D1/de active Active
-
2007
- 2007-12-10 HK HK07113464.3A patent/HK1110768A1/xx not_active IP Right Cessation
-
2010
- 2010-05-28 CY CY20101100473T patent/CY1110644T1/el unknown
- 2010-12-14 US US12/967,141 patent/US20110082200A1/en not_active Abandoned
-
2012
- 2012-03-12 JP JP2012054606A patent/JP2012107073A/ja active Pending
-
2014
- 2014-07-25 JP JP2014151656A patent/JP2014198730A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
MX2007004622A (es) | 2007-06-11 |
US20060099248A1 (en) | 2006-05-11 |
AU2005304733A1 (en) | 2006-05-18 |
KR101237534B1 (ko) | 2013-03-04 |
US7879905B2 (en) | 2011-02-01 |
CA2584286C (en) | 2014-01-14 |
HK1110768A1 (en) | 2008-07-25 |
ATE461696T1 (de) | 2010-04-15 |
US20110082200A1 (en) | 2011-04-07 |
BRPI0517972A (pt) | 2008-10-21 |
AU2005304733B2 (en) | 2011-04-07 |
WO2006052950A1 (en) | 2006-05-18 |
ES2340786T3 (es) | 2010-06-09 |
ZA200703992B (en) | 2009-08-26 |
CA2584286A1 (en) | 2006-05-18 |
PL1809270T3 (pl) | 2010-08-31 |
SI1809270T1 (sl) | 2010-07-30 |
DE602005020178D1 (de) | 2010-05-06 |
KR20070083980A (ko) | 2007-08-24 |
PT1809270E (pt) | 2010-05-25 |
JP2008519763A (ja) | 2008-06-12 |
JP2012107073A (ja) | 2012-06-07 |
DK1809270T3 (da) | 2010-06-14 |
EP1809270B1 (en) | 2010-03-24 |
EP1809270A1 (en) | 2007-07-25 |
JP2014198730A (ja) | 2014-10-23 |
CN101052387A (zh) | 2007-10-10 |
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