BRPI0112638B1 - Meio de preservação e estocagem para materiais biológicos - Google Patents
Meio de preservação e estocagem para materiais biológicos Download PDFInfo
- Publication number
- BRPI0112638B1 BRPI0112638B1 BRPI0112638-5A BR0112638A BRPI0112638B1 BR PI0112638 B1 BRPI0112638 B1 BR PI0112638B1 BR 0112638 A BR0112638 A BR 0112638A BR PI0112638 B1 BRPI0112638 B1 BR PI0112638B1
- Authority
- BR
- Brazil
- Prior art keywords
- medium
- polyhydroxy compound
- phosphate ions
- trehalose
- mixture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/625,735 US6653062B1 (en) | 2000-07-26 | 2000-07-26 | Preservation and storage medium for biological materials |
| PCT/US2001/014939 WO2002009515A1 (en) | 2000-07-26 | 2001-05-09 | Preservation and storage medium for biological materials |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR0112638A BR0112638A (pt) | 2003-06-24 |
| BRPI0112638B1 true BRPI0112638B1 (pt) | 2015-05-26 |
Family
ID=24507345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0112638-5A BRPI0112638B1 (pt) | 2000-07-26 | 2001-05-09 | Meio de preservação e estocagem para materiais biológicos |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US6653062B1 (enExample) |
| EP (1) | EP1303184B1 (enExample) |
| JP (2) | JP2004505024A (enExample) |
| KR (1) | KR100771388B1 (enExample) |
| CN (1) | CN1444442A (enExample) |
| AT (1) | ATE338458T1 (enExample) |
| AU (2) | AU2001268057B2 (enExample) |
| BR (1) | BRPI0112638B1 (enExample) |
| CA (1) | CA2412330C (enExample) |
| DE (1) | DE60122896T2 (enExample) |
| DK (1) | DK1303184T3 (enExample) |
| ES (1) | ES2273854T3 (enExample) |
| MX (1) | MXPA03000251A (enExample) |
| PT (1) | PT1303184E (enExample) |
| WO (1) | WO2002009515A1 (enExample) |
Families Citing this family (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7569342B2 (en) | 1997-12-10 | 2009-08-04 | Sierra Molecular Corp. | Removal of molecular assay interferences |
| US20080064108A1 (en) * | 1997-12-10 | 2008-03-13 | Tony Baker | Urine Preservation System |
| US6214054B1 (en) | 1998-09-21 | 2001-04-10 | Edwards Lifesciences Corporation | Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby |
| US6878168B2 (en) | 2002-01-03 | 2005-04-12 | Edwards Lifesciences Corporation | Treatment of bioprosthetic tissues to mitigate post implantation calcification |
| AU2003268033A1 (en) * | 2002-07-26 | 2004-02-16 | The General Hospital Corporation | Systems and methods for cell preservation |
| WO2004076602A1 (ja) * | 2003-02-27 | 2004-09-10 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | 脂質膜を構成している脂質の分解抑制方法及びその用途 |
| FR2861546B1 (fr) * | 2003-10-31 | 2006-05-26 | Bruno Eto | Procede de production et de conservation des produits dits "milieux physiologiques" et des produits obtenus selon ce procede |
| US7824711B2 (en) | 2003-12-11 | 2010-11-02 | Isto Technologies, Inc. | Particulate cartilage system |
| BRPI0509694A (pt) | 2004-04-08 | 2007-10-09 | Biomatrica Inc | integração de armazenamento de amostra e administração de amostra para ciências biológicas |
| US7811558B2 (en) * | 2004-08-12 | 2010-10-12 | Cellphire, Inc. | Use of stabilized platelets as hemostatic agent |
| US20060035383A1 (en) * | 2004-08-12 | 2006-02-16 | David Ho | Dry platelet preparations for use in diagnostics |
| AU2005272821B2 (en) | 2004-08-12 | 2010-09-09 | Cellphire, Inc | Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use |
| US20060051731A1 (en) * | 2004-08-12 | 2006-03-09 | David Ho | Processes for preparing lyophilized platelets |
| MY142987A (en) * | 2005-06-08 | 2011-02-14 | Hayashibara Biochem Lab | Solution for tissue adhesion prevention and method for tissue adhesion prevention |
| EP1916964A4 (en) | 2005-08-26 | 2015-11-04 | Zimmer Inc | IMPLANTS AND METHODS FOR THE REPAIR, REPLACEMENT AND TREATMENT OF JOINT DISEASES |
| US8168206B1 (en) | 2005-10-06 | 2012-05-01 | Allergan, Inc. | Animal protein-free pharmaceutical compositions |
| US8137677B2 (en) * | 2005-10-06 | 2012-03-20 | Allergan, Inc. | Non-protein stabilized clostridial toxin pharmaceutical compositions |
| US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| JP5214464B2 (ja) | 2005-12-28 | 2013-06-19 | アドバンスド バイオニュートリション コーポレーション | 多糖類、糖類およびポリオール類の乾燥マトリックスを含む、ガラス形態の、プロバイオティクス細菌用送達媒体およびその製造方法 |
| CN101626682B (zh) | 2006-10-27 | 2014-04-16 | 爱德华兹生命科学公司 | 用于外科植入的生物组织 |
| US8097403B2 (en) * | 2006-12-14 | 2012-01-17 | Cellphire, Inc. | Freeze-dried platelets, method of making and method of use as a diagnostic agent |
| WO2008076975A1 (en) * | 2006-12-18 | 2008-06-26 | Advanced Bionutrition Corporation | A dry food product containing live probiotic |
| US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
| AU2008240191B2 (en) | 2007-04-12 | 2013-09-19 | Zimmer, Inc. | Compositions and methods for tissue repair |
| US9101691B2 (en) | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
| US20090081785A1 (en) * | 2007-09-24 | 2009-03-26 | Hememics Biotechnologies, Inc. | Desiccated Biologics And Methods Of Preparing The Same |
| US20090090022A1 (en) * | 2007-10-09 | 2009-04-09 | Hememics Biotechnologies, Inc. | Desiccation Chamber and Methods for Drying Biological Materials |
| DE102007052281A1 (de) * | 2007-11-02 | 2009-05-07 | Zenteris Gmbh | Einschritt-Multiplex-Immuntest |
| US8835104B2 (en) | 2007-12-20 | 2014-09-16 | Fenwal, Inc. | Medium and methods for the storage of platelets |
| US8357387B2 (en) | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
| US8735054B1 (en) | 2008-01-04 | 2014-05-27 | Lifecell Corporation | Acellular tissue matrix preservation solution |
| US8871434B2 (en) * | 2008-03-21 | 2014-10-28 | Fenwal, Inc. | Red blood cell storage medium for extended storage |
| US8968992B2 (en) * | 2008-03-21 | 2015-03-03 | Fenwal, Inc. | Red blood cell storage medium for extended storage |
| US9150318B1 (en) | 2009-01-02 | 2015-10-06 | Lifecell Corporation | Method for sterilizing an acellular tissue matrix |
| CA2986751A1 (en) | 2009-03-27 | 2010-09-30 | Intervet International B.V. | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
| KR20120015335A (ko) | 2009-05-01 | 2012-02-21 | 마이크로파마 리미티드 | 퇴행성 질환의 예방 및 치료를 위한 박테리아 조성물 |
| AU2010254235B2 (en) | 2009-05-26 | 2015-04-02 | Advanced Bionutrition Corporation | Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making |
| EP2451398B1 (en) | 2009-07-10 | 2015-10-28 | Kirk Promotion LTD. | Hip joint device |
| NZ597968A (en) | 2009-08-14 | 2014-01-31 | Dupont Nutrition Biosci Aps | Coated dehydrated microorganisms with enhanced stability and viability |
| US11864553B2 (en) | 2009-10-23 | 2024-01-09 | Fenwal, Inc. | Methods and systems for providing red blood cell products with reduced plasma |
| US20110110975A1 (en) * | 2009-11-06 | 2011-05-12 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
| US20110183311A1 (en) * | 2010-01-27 | 2011-07-28 | David Ho | Dry platelet preparations for use in diagnostics |
| CA2785815C (en) | 2010-01-28 | 2018-04-24 | Advanced Bionutrition Corporation | Dry glassy composition comprising a bioactive material |
| US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
| EP2547760A4 (en) | 2010-02-17 | 2014-01-01 | Hememics Biotechnologies Inc | PRESERVATION SOLUTIONS FOR BIOLOGICS AND RELATED METHODS |
| US8679404B2 (en) | 2010-03-05 | 2014-03-25 | Edwards Lifesciences Corporation | Dry prosthetic heart valve packaging system |
| EP2674174B1 (en) | 2010-03-23 | 2019-10-16 | Edwards Lifesciences Corporation | Methods of conditioning sheet bioprosthetic tissue |
| US8906601B2 (en) | 2010-06-17 | 2014-12-09 | Edwardss Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
| EP2582411B1 (en) | 2010-06-17 | 2019-05-01 | Edwards Lifesciences Corporation | Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates |
| WO2012018638A2 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures |
| EP2598661B1 (en) | 2010-07-26 | 2017-09-27 | Biomatrica, INC. | Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
| ES2676656T3 (es) | 2010-08-13 | 2018-07-23 | Advanced Bionutrition Corp. | Composición estabilizante de almacenamiento en seco para materiales biológicos |
| US9351829B2 (en) | 2010-11-17 | 2016-05-31 | Edwards Lifesciences Corporation | Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability |
| US9498317B2 (en) | 2010-12-16 | 2016-11-22 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery systems and packaging |
| US8512679B2 (en) * | 2011-03-04 | 2013-08-20 | Elwha Llc | Glassy compositions |
| EP2694131B1 (en) | 2011-04-07 | 2019-08-28 | Fenwal, Inc. | Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates |
| EP2704740B1 (en) | 2011-05-04 | 2016-10-05 | Streck, Inc. | Inactivated swine flu virus and methods of preparing it |
| SG11201401360XA (en) | 2011-10-25 | 2014-05-29 | Onclave Therapeutics Ltd | Antibody formulations and methods |
| US9901648B2 (en) | 2012-01-27 | 2018-02-27 | The Regents Of The University Of California | Stabilization of biomolecules using sugar polymers |
| FR2992861B1 (fr) | 2012-07-09 | 2014-10-17 | Probionov | Utilisation de thiosulfate pour potentialiser l'effet anti-pathogene des lactobacilles |
| CN103027032B (zh) * | 2012-09-29 | 2014-09-17 | 浙江大学 | 一种鼠李糖脂作为细胞低温或超低温保存的保护剂应用 |
| US10238771B2 (en) | 2012-11-08 | 2019-03-26 | Edwards Lifesciences Corporation | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system |
| EP3249054A1 (en) | 2012-12-20 | 2017-11-29 | Biomatrica, INC. | Formulations and methods for stabilizing pcr reagents |
| US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
| TWI453179B (zh) * | 2013-02-19 | 2014-09-21 | Chunghwa Picture Tubes Ltd | 顆粒狀肥料及其製造方法 |
| CN103564617A (zh) * | 2013-09-18 | 2014-02-12 | 黄雨诗 | 一种动植物体微冰晶冷冻保鲜助冻剂及使用方法 |
| US9615922B2 (en) | 2013-09-30 | 2017-04-11 | Edwards Lifesciences Corporation | Method and apparatus for preparing a contoured biological tissue |
| US10959839B2 (en) | 2013-10-08 | 2021-03-30 | Edwards Lifesciences Corporation | Method for directing cellular migration patterns on a biological tissue |
| SG11201604136PA (en) * | 2013-12-19 | 2016-07-28 | Crucell Holland Bv | Improved formulations for virosomes |
| EP3942931A1 (en) | 2014-06-10 | 2022-01-26 | Biomatrica, INC. | Stabilization of thrombocytes at ambient temperatures |
| KR102685914B1 (ko) | 2015-07-29 | 2024-07-16 | 어드밴스드 바이오뉴트리션 코프. | 특수 식이 용도를 위한 안정한 프로바이오틱 건조 조성물 |
| US10844347B2 (en) | 2015-10-30 | 2020-11-24 | Kabushiki Kaisha Yakult Honsha | Method for producing dried microbial cells |
| HRP20220407T1 (hr) | 2015-11-09 | 2022-05-27 | The Regents Of The University Of Colorado, A Body Corporate | Pripravci i postupci za uporabu u liječenju homocistinurije |
| MX395197B (es) | 2015-12-04 | 2025-03-19 | Advanced Bionutrition Corp | Composiciones secas estables que no tienen o contienen pocos azucares. |
| KR20250047404A (ko) | 2015-12-08 | 2025-04-03 | 바이오매트리카 인코포레이티드 | 적혈구 침강 속도의 감소 |
| HUE046449T2 (hu) | 2016-09-13 | 2020-03-30 | Allergan Inc | Stabilizált, nem fehérje eredetû, clostridiális toxin készítmények |
| PL3571287T3 (pl) | 2017-01-19 | 2024-05-13 | International N&H Denmark Aps | Wysuszony mikroorganizm z substancją pomocniczą |
| CN110678590B (zh) | 2017-05-31 | 2022-07-19 | 爱德华兹生命科学公司 | 胶原纤维和由其形成的制品 |
| US12042519B2 (en) | 2017-07-14 | 2024-07-23 | The University Of Chicago | Freeze-dried formulations including nanoparticles and methods of freeze-drying |
| CA3081049A1 (en) | 2018-01-23 | 2019-08-01 | Edwards Lifesciences Corporation | Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby |
| CN109260517B (zh) * | 2018-09-19 | 2020-10-30 | 杭州启明医疗器械股份有限公司 | 一种可预装干燥生物心脏瓣膜及其制备方法 |
| WO2020092205A1 (en) | 2018-11-01 | 2020-05-07 | Edwards Lifesciences Corporation | Transcatheter pulmonic regenerative valve |
| US11767511B2 (en) | 2018-11-30 | 2023-09-26 | Cellphire, Inc. | Platelets as delivery agents |
| WO2020113090A1 (en) | 2018-11-30 | 2020-06-04 | Cellphire, Inc. | Platelets as delivery agents |
| IT201900006056A1 (it) * | 2019-04-18 | 2020-10-18 | Probiotical Spa | Procedimento per la preparazione di una biomassa di cellule di batteri liofilizzate stabili e determinazione della loro stabilità mediante un metodo citofluorimetrico |
| IT201900006066A1 (it) * | 2019-04-18 | 2020-10-18 | Probiotical Spa | Uso di un metodo citofluorimetrico per valutare la stabilità e vitalità di una biomassa di cellule di batteri liofilizzate |
| CA3138529C (en) | 2019-05-03 | 2025-10-07 | Cellphire Inc | Materials and methods for producing blood products |
| FI3990005T3 (fi) | 2019-06-26 | 2025-11-28 | Travere Therapeutics Switzerland Gmbh | Pegyloitu kystationiini-beta-syntaasi entsyymihoitoa varten homokystinurian hoitamiseksi |
| WO2021034719A1 (en) | 2019-08-16 | 2021-02-25 | Cellphire, Inc. | Thrombosomes as an antiplatelet agent reversal agent |
| CA3170134A1 (en) | 2020-02-04 | 2021-08-12 | Cellphire, Inc. | Treatment of von willebrand disease |
| US12426594B2 (en) | 2020-09-24 | 2025-09-30 | Everest Medical Innovation GmbH | Cryoprotective compositions and methods for protection of a surgical site during cryosurgery |
| US12453805B2 (en) | 2020-09-24 | 2025-10-28 | Everest Medical Innovation GmbH | Cryoprotective compositions, surgical kits, and methods for protection of a surgical site during cryosurgery |
| WO2022076535A1 (en) | 2020-10-06 | 2022-04-14 | Danisco Us Inc. | Readily dispersible shelf-stable bioactive granules |
| US20220273724A1 (en) | 2021-02-17 | 2022-09-01 | Cellphire Inc. | Freeze-dried platelet derivative compositions for treating antiplatelet induced coagulopathy |
| WO2024233577A1 (en) | 2023-05-11 | 2024-11-14 | Vetstem, Inc. | Platelet-rich plasma compositions, preparation, and uses thereof |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1173360A (en) * | 1979-06-22 | 1984-08-28 | Jurg Schrank | Pharmaceutical preparations |
| FR2542617B2 (fr) | 1982-07-09 | 1986-06-06 | Rgl Transfusion Sanguine Centr | Solution protectrice pour la conservation de cellules fonctionnelles |
| FR2529787B1 (fr) * | 1982-07-09 | 1985-08-02 | Rgl Transfusion Sanguine Centr | Solution protectrice pour la conservation de cellules fonctionnelles |
| JPS6197229A (ja) | 1984-10-18 | 1986-05-15 | Chugai Pharmaceut Co Ltd | 安定なエリトロポエチン製剤 |
| US4857319A (en) | 1985-01-11 | 1989-08-15 | The Regents Of The University Of California | Method for preserving liposomes |
| DE229810T1 (de) * | 1985-07-09 | 1987-11-05 | Quadrant Bioresources Ltd., Soulbury, Leighton Buzzard, Bedfordshire | Beschuetzung von proteinen und aehnlichem. |
| US4798824A (en) | 1985-10-03 | 1989-01-17 | Wisconsin Alumni Research Foundation | Perfusate for the preservation of organs |
| US4806343A (en) * | 1986-03-13 | 1989-02-21 | University Of Southwestern Louisiana | Cryogenic protectant for proteins |
| GB8715238D0 (en) | 1987-06-29 | 1987-08-05 | Quadrant Bioresources Ltd | Food process |
| GB8801338D0 (en) | 1988-01-21 | 1988-02-17 | Quadrant Bioresources Ltd | Preservation of viruses |
| US5045446A (en) | 1988-08-26 | 1991-09-03 | Cryopharm Corporation | Lyophilization of cells |
| US5171661A (en) | 1988-05-18 | 1992-12-15 | Cryopharm Corporation | Medium for lyophilization of erythrocytes |
| US5252496A (en) | 1989-12-18 | 1993-10-12 | Princeton Biomeditech Corporation | Carbon black immunochemical label |
| US5621094A (en) | 1990-05-14 | 1997-04-15 | Quadrant Holdings Cambridge Limited | Method of preserving agarose gel structure during dehydration by adding a non-reducing glycoside of a straight-chain sugar alcohol |
| US5314595A (en) | 1992-04-03 | 1994-05-24 | United States Biochemical Corporation | Electrophoresis of nucleic acid fragments |
| JPH05292943A (ja) * | 1992-04-23 | 1993-11-09 | Nakano Vinegar Co Ltd | 微生物の保存方法 |
| DE69332756T2 (de) * | 1992-05-29 | 2004-02-19 | University Of North Carolina At Chapel Hill | Im immobilisierten zustand getrocknete pharmazeutische verträgliche menschliche blutplättchen |
| GB9215587D0 (en) * | 1992-07-22 | 1992-09-02 | Field Group Ltd | Cartons |
| JP3253131B2 (ja) | 1992-07-24 | 2002-02-04 | 洋巳 和田 | 移植臓器用溶液 |
| CZ296649B6 (cs) | 1993-02-23 | 2006-05-17 | Genentech, Inc. | Zpusob výroby stabilizovaného polypeptidového prostredku zahrnující stabilizování polypeptidu protidenaturaci organickými rozpoustedly, jeho príprava a prostredek pro regulované uvolnování polypeptidu |
| JP3125610B2 (ja) * | 1993-12-24 | 2001-01-22 | 和光純薬工業株式会社 | L−メチオニン γ−リアーゼの安定化法 |
| GB9401447D0 (en) * | 1994-01-26 | 1994-03-23 | Ciba Geigy Ag | Pharmaceutical compositions |
| DE4405426A1 (de) * | 1994-02-21 | 1995-08-24 | Boehringer Mannheim Gmbh | Pharmazeutisches Präparat enthaltend Plasminogenaktivator (t-PA) oder dessen Derivate |
| JP3788522B2 (ja) * | 1994-02-22 | 2006-06-21 | 日本電信電話株式会社 | 血球、幹細胞、および血小板の凍結乾燥生成物の製造方法 |
| US5955448A (en) | 1994-08-19 | 1999-09-21 | Quadrant Holdings Cambridge Limited | Method for stabilization of biological substances during drying and subsequent storage and compositions thereof |
| FR2719479B1 (fr) | 1994-05-04 | 1996-07-26 | Sanofi Elf | Formulation stable lyophilisée comprenant une protéine: kit de dosage. |
| US5512547A (en) | 1994-10-13 | 1996-04-30 | Wisconsin Alumni Research Foundation | Pharmaceutical composition of botulinum neurotoxin and method of preparation |
| US5556771A (en) | 1995-02-10 | 1996-09-17 | Gen-Probe Incorporated | Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification |
| US6964771B1 (en) * | 1995-06-07 | 2005-11-15 | Elan Drug Delivery Limited | Method for stably incorporating substances within dry, foamed glass matrices |
| CZ391297A3 (cs) | 1995-06-07 | 1998-05-13 | Quadrant Holdings Cambridge Limited | Způsob přípravy tenké porovité skelné matrice a prostředek tím získaný |
| US5690963A (en) * | 1995-06-30 | 1997-11-25 | The United States Of America As Represented By The Secretary Of The Navy | Freeze dried red blood cells |
| JP2930908B2 (ja) * | 1995-07-19 | 1999-08-09 | 川澄化学工業株式会社 | 血小板保存液 |
| US5736313A (en) * | 1995-10-20 | 1998-04-07 | The United States Of America As Represented By The Secretary Of The Navy | Method of lyophilizing platelets by incubation with high carbohydrate concentrations and supercooling prior to freezing |
| US5827741A (en) * | 1996-11-19 | 1998-10-27 | The Regents Of The University Of California | Cryopreservation of human adult and fetal pancreatic cells and human platelets |
| US6468782B1 (en) | 1996-12-05 | 2002-10-22 | Quadrant Healthcare (Uk) Limited | Methods of preserving prokaryotic cells and compositions obtained thereby |
| ATE230923T1 (de) * | 1997-02-07 | 2003-02-15 | Elan Drug Delivery Ltd | Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen |
| GB9705588D0 (en) | 1997-03-18 | 1997-05-07 | Anglia Research Foundation | Stable particle in liquid formulations |
| WO1999047174A1 (en) | 1998-03-18 | 1999-09-23 | Cambridge Biostability Limited | Amorphous glasses for stabilising sensitive products |
| DE60002103T2 (de) * | 1999-11-12 | 2003-12-18 | Elan Drug Delivery Ltd., Ruddington | Stabilisierung von blutplättchen |
| AU2001234978A1 (en) | 2000-02-10 | 2001-08-20 | The Regents Of The University Of California | Therapeutic platelets and methods |
| US6770478B2 (en) * | 2000-02-10 | 2004-08-03 | The Regents Of The University Of California | Erythrocytic cells and method for preserving cells |
| US20020076445A1 (en) * | 2000-02-10 | 2002-06-20 | Crowe John H. | Eukaryotic cells and method for preserving cells |
-
2000
- 2000-07-26 US US09/625,735 patent/US6653062B1/en not_active Expired - Lifetime
-
2001
- 2001-05-09 ES ES01945951T patent/ES2273854T3/es not_active Expired - Lifetime
- 2001-05-09 AU AU2001268057A patent/AU2001268057B2/en not_active Expired
- 2001-05-09 WO PCT/US2001/014939 patent/WO2002009515A1/en not_active Ceased
- 2001-05-09 KR KR1020037000995A patent/KR100771388B1/ko not_active Expired - Lifetime
- 2001-05-09 CA CA002412330A patent/CA2412330C/en not_active Expired - Lifetime
- 2001-05-09 CN CN01813325A patent/CN1444442A/zh active Pending
- 2001-05-09 DE DE60122896T patent/DE60122896T2/de not_active Expired - Lifetime
- 2001-05-09 AT AT01945951T patent/ATE338458T1/de not_active IP Right Cessation
- 2001-05-09 PT PT01945951T patent/PT1303184E/pt unknown
- 2001-05-09 JP JP2002515080A patent/JP2004505024A/ja active Pending
- 2001-05-09 MX MXPA03000251A patent/MXPA03000251A/es active IP Right Grant
- 2001-05-09 EP EP01945951A patent/EP1303184B1/en not_active Expired - Lifetime
- 2001-05-09 AU AU6805701A patent/AU6805701A/xx active Pending
- 2001-05-09 DK DK01945951T patent/DK1303184T3/da active
- 2001-05-09 BR BRPI0112638-5A patent/BRPI0112638B1/pt not_active IP Right Cessation
-
2003
- 2003-09-05 US US10/657,017 patent/US6919172B2/en not_active Expired - Lifetime
-
2004
- 2004-03-12 US US10/799,462 patent/US7169606B2/en not_active Expired - Fee Related
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2007
- 2007-09-18 JP JP2007241092A patent/JP4889602B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60122896D1 (de) | 2006-10-19 |
| BR0112638A (pt) | 2003-06-24 |
| US20040043374A1 (en) | 2004-03-04 |
| KR100771388B1 (ko) | 2007-10-31 |
| WO2002009515B1 (en) | 2002-06-27 |
| AU2001268057B2 (en) | 2005-06-09 |
| CA2412330C (en) | 2009-02-10 |
| DE60122896T2 (de) | 2007-04-05 |
| US6919172B2 (en) | 2005-07-19 |
| AU6805701A (en) | 2002-02-13 |
| ATE338458T1 (de) | 2006-09-15 |
| JP4889602B2 (ja) | 2012-03-07 |
| US7169606B2 (en) | 2007-01-30 |
| US20040209236A1 (en) | 2004-10-21 |
| KR20030031561A (ko) | 2003-04-21 |
| WO2002009515A1 (en) | 2002-02-07 |
| CN1444442A (zh) | 2003-09-24 |
| EP1303184A1 (en) | 2003-04-23 |
| JP2004505024A (ja) | 2004-02-19 |
| DK1303184T3 (da) | 2007-01-08 |
| JP2008044953A (ja) | 2008-02-28 |
| CA2412330A1 (en) | 2002-02-07 |
| EP1303184B1 (en) | 2006-09-06 |
| PT1303184E (pt) | 2007-01-31 |
| US6653062B1 (en) | 2003-11-25 |
| ES2273854T3 (es) | 2007-05-16 |
| MXPA03000251A (es) | 2003-06-06 |
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