BR9913948A - Composição farmacêutica para o tratamento de dor aguda por administração sublingual, uso de fentanila ou um sal farmaceuticamente aceitável da mesma, e processo para o tratamento de dor aguda - Google Patents

Composição farmacêutica para o tratamento de dor aguda por administração sublingual, uso de fentanila ou um sal farmaceuticamente aceitável da mesma, e processo para o tratamento de dor aguda

Info

Publication number
BR9913948A
BR9913948A BR9913948-0A BR9913948A BR9913948A BR 9913948 A BR9913948 A BR 9913948A BR 9913948 A BR9913948 A BR 9913948A BR 9913948 A BR9913948 A BR 9913948A
Authority
BR
Brazil
Prior art keywords
treatment
acute pain
fentanyl
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
BR9913948-0A
Other languages
English (en)
Other versions
BR9913948B1 (pt
Inventor
Anders Pettersson
Nyrstroem Christer
Hans Lennernos
Bo Lennernos
Thomas Hedner
Original Assignee
Diabact Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20412701&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9913948(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Diabact Ab filed Critical Diabact Ab
Publication of BR9913948A publication Critical patent/BR9913948A/pt
Publication of BR9913948B1 publication Critical patent/BR9913948B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"COMPOSIçãO FARMACêUTICA PARA O TRATAMENTO DE DOR AGUDA POR ADMINISTRAçãO SUBLINGUAL, USO DE FENTANILA OU UM SAL FARMACEUTICAMENTE ACEITáVEL DA MESMA, E PROCESSO PARA O TRATAMENTO DE DOR AGUDA" Uma composição farmacêutica para o tratamento de dor aguda por administração sublingual é descrita. A composição compreende uma mistura ordenada, essencialmente isenta de água, de fentanila ou um sal farmaceuticamente aceitável da mesma, na forma de micro partículas que são aderidas à superfície das partículas portadoras que são substancialmente maiores do que as partículas de fentanila, e são essencialmente solúveis em água em água. Em uma forma de realização preferida, a composição também contém um agente promotor de bioadesão e/ou mucoadesão. A invenção também se refere à preparação da composição, e ao uso de composição para o tratamento de dor aguda.
BRPI9913948-0A 1998-09-24 1999-09-24 composição farmacêutica para o tratamento de dor aguda por administração sublingual, uso de fentanila ou um sal farmaceuticamente aceitável da mesma, e, uso de uma composição farmacêutica essencialmente isenta de água. BR9913948B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9803239-4 1998-09-24
SE9803239A SE9803239D0 (sv) 1998-09-24 1998-09-24 Composition for the treatment of acute pain
PCT/SE1999/001688 WO2000016751A1 (en) 1998-09-24 1999-09-24 Fentanyl composition for the treatment of acute pain

Publications (2)

Publication Number Publication Date
BR9913948A true BR9913948A (pt) 2001-06-12
BR9913948B1 BR9913948B1 (pt) 2011-02-08

Family

ID=20412701

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9913948-0A BR9913948B1 (pt) 1998-09-24 1999-09-24 composição farmacêutica para o tratamento de dor aguda por administração sublingual, uso de fentanila ou um sal farmaceuticamente aceitável da mesma, e, uso de uma composição farmacêutica essencialmente isenta de água.

Country Status (26)

Country Link
US (1) US6759059B1 (pt)
EP (1) EP1115384B1 (pt)
JP (2) JP2002526440A (pt)
KR (1) KR100760531B1 (pt)
CN (1) CN1170524C (pt)
AT (1) ATE247950T1 (pt)
AU (1) AU764473B2 (pt)
BG (1) BG65363B1 (pt)
BR (1) BR9913948B1 (pt)
CA (1) CA2345064C (pt)
CZ (1) CZ301562B6 (pt)
DE (1) DE69910803T2 (pt)
DK (1) DK1115384T3 (pt)
EE (1) EE200100176A (pt)
ES (1) ES2207295T3 (pt)
HU (2) HU228992B1 (pt)
IL (2) IL142126A0 (pt)
NO (1) NO332228B1 (pt)
NZ (1) NZ510646A (pt)
PL (1) PL197078B1 (pt)
PT (1) PT1115384E (pt)
RU (1) RU2232580C2 (pt)
SE (1) SE9803239D0 (pt)
SK (1) SK283503B6 (pt)
TR (1) TR200100812T2 (pt)
WO (1) WO2000016751A1 (pt)

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Also Published As

Publication number Publication date
IL142126A (en) 2006-04-10
SK4012001A3 (en) 2001-10-08
EE200100176A (et) 2002-08-15
NO332228B1 (no) 2012-07-30
HUP0103621A2 (hu) 2002-02-28
SK283503B6 (sk) 2003-08-05
SE9803239D0 (sv) 1998-09-24
KR100760531B1 (ko) 2007-10-04
NO20011502D0 (no) 2001-03-23
EP1115384B1 (en) 2003-08-27
PT1115384E (pt) 2004-01-30
ATE247950T1 (de) 2003-09-15
DE69910803D1 (de) 2003-10-02
JP4478512B2 (ja) 2010-06-09
BG65363B1 (bg) 2008-04-30
NZ510646A (en) 2004-04-30
EP1115384A1 (en) 2001-07-18
CZ20011030A3 (cs) 2001-09-12
DK1115384T3 (da) 2003-12-22
BG105380A (en) 2001-12-29
HUP0103621A3 (en) 2005-05-30
NO20011502L (no) 2001-03-23
IL142126A0 (en) 2002-03-10
AU6492899A (en) 2000-04-10
PL347467A1 (en) 2002-04-08
US6759059B1 (en) 2004-07-06
TR200100812T2 (tr) 2001-07-23
JP2002526440A (ja) 2002-08-20
CA2345064C (en) 2008-05-27
KR20010075314A (ko) 2001-08-09
HU228992B1 (en) 2013-07-29
DE69910803T2 (de) 2004-06-17
CN1328448A (zh) 2001-12-26
PL197078B1 (pl) 2008-02-29
CN1170524C (zh) 2004-10-13
CA2345064A1 (en) 2000-03-30
CZ301562B6 (cs) 2010-04-14
ES2207295T3 (es) 2004-05-16
HU230688B1 (hu) 2017-09-28
BR9913948B1 (pt) 2011-02-08
AU764473B2 (en) 2003-08-21
RU2232580C2 (ru) 2004-07-20
JP2004269545A (ja) 2004-09-30
WO2000016751A1 (en) 2000-03-30

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