BR9904039A - Preparação de partìculas farmaceuticamente ativas - Google Patents
Preparação de partìculas farmaceuticamente ativasInfo
- Publication number
- BR9904039A BR9904039A BR9904039-5A BR9904039A BR9904039A BR 9904039 A BR9904039 A BR 9904039A BR 9904039 A BR9904039 A BR 9904039A BR 9904039 A BR9904039 A BR 9904039A
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- particles
- pharmaceutically active
- active particles
- coating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
Abstract
Patente de Invenção: <B>"PREPARAçãO DE PARTìCULAS FARMACEUTICAMENTE ATIVAS"<D>. A presente invenção fornece um núcleo de celulose predominantemente microcristalina sobre o qual uma droga ativa é depositada em camadas sobre o núcleo por meio de revestimento de solução. As partículas revestidas têm uma distribuição mais limitada de tamanho de partícula do que os grânulos fornecidos por outros processos. é fornecido um revestimento final opcional de um revestimento polimérico farmaceuticamente aceitável para fornecer mascaração do sabor ou liberação controlada e proteção das partículas com droga depositada em camadas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/148,251 US5997905A (en) | 1998-09-04 | 1998-09-04 | Preparation of pharmaceutically active particles |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9904039A true BR9904039A (pt) | 2001-01-16 |
Family
ID=22524956
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9904039-5A BR9904039A (pt) | 1998-09-04 | 1999-09-02 | Preparação de partìculas farmaceuticamente ativas |
Country Status (9)
Country | Link |
---|---|
US (2) | US5997905A (pt) |
EP (1) | EP1000615B1 (pt) |
JP (1) | JP2000109426A (pt) |
CN (1) | CN1151844C (pt) |
AU (1) | AU773833B2 (pt) |
BR (1) | BR9904039A (pt) |
CA (1) | CA2281420C (pt) |
DE (1) | DE69921941T2 (pt) |
ES (1) | ES2233003T3 (pt) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW522014B (en) * | 1997-02-07 | 2003-03-01 | Sepracor Inc | Lactose-free, non-hygroscopic and anhydrous pharmaceutical unit dosage form containing descarboethoxyloratadine |
US5997905A (en) * | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
CA2345945A1 (en) | 1998-10-01 | 2000-04-13 | Powderject Research Limited | Spray coated microparticles for use in needleless syringes |
US20050214227A1 (en) * | 1999-03-08 | 2005-09-29 | Powderject Research Limited | Microparticle formulations for sustained-release of bioactive compounds |
ES2162746B1 (es) * | 1999-10-21 | 2003-02-16 | Lipotec Sa | Microcapsulas para la estabilizacion de productos cosmeticos, farmaceuticos o de alimentacion. |
ES2239048T3 (es) * | 1999-11-12 | 2005-09-16 | R.P. Scherer Technologies, Inc. | Granulos protectores de celulosa microcristalina. |
UA84534C2 (uk) * | 2000-02-29 | 2008-11-10 | Брістол-Майерс Сквібб Ко. | Композиція з низькою дозою ентекавіру |
US6392034B1 (en) | 2000-05-17 | 2002-05-21 | Jh Biotech, Inc. | Microcrystalline cellulose |
WO2002019989A2 (en) * | 2000-09-08 | 2002-03-14 | Powderject Research Limited | Alginate particle formulation |
US6692771B2 (en) | 2001-02-23 | 2004-02-17 | Cima Labs Inc. | Emulsions as solid dosage forms for oral administration |
EP1361866A4 (en) * | 2001-02-23 | 2007-10-17 | Cima Labs Inc | EMULSIONS AS SOLID DOSAGE FORMS FOR ORAL ADMINISTRATION |
EP1390015A1 (en) * | 2001-05-31 | 2004-02-25 | Cima Labs Inc. | Taste-masking of highly water-soluble drugs |
JP2005506323A (ja) * | 2001-09-05 | 2005-03-03 | ベクトゥラ・リミテッド | 経口送達用機能性散剤 |
BR0206086A (pt) | 2001-09-28 | 2003-12-23 | Mcneil Ppc Inc | Formas de dosagem de liberação modificada |
US7323192B2 (en) | 2001-09-28 | 2008-01-29 | Mcneil-Ppc, Inc. | Immediate release tablet |
US6982094B2 (en) * | 2001-09-28 | 2006-01-03 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
US7838026B2 (en) | 2001-09-28 | 2010-11-23 | Mcneil-Ppc, Inc. | Burst-release polymer composition and dosage forms comprising the same |
US7217381B2 (en) | 2001-09-28 | 2007-05-15 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
US6837696B2 (en) * | 2001-09-28 | 2005-01-04 | Mcneil-Ppc, Inc. | Apparatus for manufacturing dosage forms |
US6742646B2 (en) * | 2001-09-28 | 2004-06-01 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
US7122143B2 (en) | 2001-09-28 | 2006-10-17 | Mcneil-Ppc, Inc. | Methods for manufacturing dosage forms |
US6767200B2 (en) * | 2001-09-28 | 2004-07-27 | Mcneil-Ppc, Inc. | Systems, methods and apparatuses for manufacturing dosage forms |
IL146462A (en) | 2001-11-13 | 2015-02-26 | Lycored Bio Ltd | Prolonged-release preparations containing as an active compound and analapaxin hydrochloride |
UA76810C2 (uk) | 2001-12-10 | 2006-09-15 | Мерк Енд Ко., Інк. | Фармацевтична композиція антагоніста рецептора тахікініну у формі наночастинок |
CO5400144A1 (es) * | 2002-03-11 | 2004-05-31 | Novartis Ag | Compuestos organicos |
TWI275392B (en) * | 2002-04-08 | 2007-03-11 | Bristol Myers Squibb Co | Low dose liquid entecavir formulations and use |
US20040033257A1 (en) * | 2002-05-30 | 2004-02-19 | Strides Inc. | Pharmaceutical formulation in a drug delivery system and process for preparing the same |
US7807197B2 (en) | 2002-09-28 | 2010-10-05 | Mcneil-Ppc, Inc. | Composite dosage forms having an inlaid portion |
DK3473251T3 (da) * | 2002-12-20 | 2024-01-22 | Niconovum Ab | Nikotin-cellulose-kombination |
BRPI0414541B8 (pt) * | 2003-09-17 | 2021-05-25 | Janssen Pharmaceutica Nv | compostos heterocíclicos fundidos tendo atividade de modulação de receptor de serotonina, método de preparação de compostos intermediários |
US20050074514A1 (en) * | 2003-10-02 | 2005-04-07 | Anderson Oliver B. | Zero cycle molding systems, methods and apparatuses for manufacturing dosage forms |
US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
FR2864962B1 (fr) * | 2004-01-08 | 2007-09-14 | Seppic Sa | Nouveaux granules filmogenes poreux, procede pour leur preparation et application dans le pelliculage des comprimes et confiseries |
JP2005306778A (ja) * | 2004-04-21 | 2005-11-04 | Basf Ag | 徐放性製剤及びその製造方法 |
US20060019933A1 (en) * | 2004-07-22 | 2006-01-26 | David Boardman | Process for preparing stabilized vitamin D |
DE102004035938A1 (de) * | 2004-07-23 | 2006-02-16 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von überzogenen Arzneiformen mit stabilem Wirkstofffreigabeprofil |
US20060068009A1 (en) * | 2004-09-30 | 2006-03-30 | Scolr Pharma, Inc. | Modified release ibuprofen dosage form |
US20070077297A1 (en) * | 2004-09-30 | 2007-04-05 | Scolr Pharma, Inc. | Modified release ibuprofen dosage form |
US20060127479A1 (en) * | 2004-10-08 | 2006-06-15 | Natrajan Kumaraperumal | Solvent free taste masked pharmaceutical compositions |
ES2231043B2 (es) * | 2004-10-29 | 2005-10-01 | Laboratorios Cinfa, S.A. | Composicion farmaceutica de ebastina de liberacion inmediata y su proceso de fabricacion. |
AU2005306464A1 (en) * | 2004-11-18 | 2006-05-26 | Bristol-Myers Squibb Company | Enteric coated bead comprising Ixabepilone, and preparation thereof |
WO2006055742A1 (en) * | 2004-11-18 | 2006-05-26 | Bristol-Myers Squibb Company | Enteric coated bead comprising epothilone or epothilone analog, and preparation and administration thereof |
US8673352B2 (en) | 2005-04-15 | 2014-03-18 | Mcneil-Ppc, Inc. | Modified release dosage form |
US20080020040A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Unit dose form for administration of ibuprofen |
US20080021078A1 (en) * | 2006-07-18 | 2008-01-24 | Horizon Therapeutics, Inc. | Methods and medicaments for administration of ibuprofen |
US20070043096A1 (en) * | 2005-07-18 | 2007-02-22 | Horizon Therapeutics, Inc. | Unit dose form with ibuprofen-famotidine admixture |
US8067451B2 (en) * | 2006-07-18 | 2011-11-29 | Horizon Pharma Usa, Inc. | Methods and medicaments for administration of ibuprofen |
US7598255B2 (en) | 2005-08-04 | 2009-10-06 | Janssen Pharmaceutica Nv | Pyrimidine compounds as serotonin receptor modulators |
US8815285B2 (en) * | 2006-03-28 | 2014-08-26 | Wockhardt Ltd. | Extended release dosage forms of metoprolol |
EP2010177A2 (en) * | 2006-04-10 | 2009-01-07 | Janssen Pharmaceutica N.V. | Combination histamine h1r and h4r antagonist therapy for treating pruritus |
US8067033B2 (en) | 2007-11-30 | 2011-11-29 | Horizon Pharma Usa, Inc. | Stable compositions of famotidine and ibuprofen |
EP2042162B1 (en) * | 2006-07-19 | 2017-10-04 | Asahi Kasei Kabushiki Kaisha | Process for producing spherical elementary granule containing readily water-soluble drug |
JP5271081B2 (ja) * | 2006-07-26 | 2013-08-21 | 旭化成ケミカルズ株式会社 | 球形素顆粒およびその製造方法 |
WO2008027963A2 (en) * | 2006-08-31 | 2008-03-06 | Horizon Therapeutics, Inc. | Nsaid dose unit formulations with h2-receptor antagonists and methods of use |
CA2669410C (en) * | 2006-11-21 | 2015-07-14 | Mcneil-Ppc, Inc. | Modified release analgesic suspensions |
US8298585B2 (en) * | 2007-06-06 | 2012-10-30 | Asahi Kasei Chemicals Corporation | Cellulose-based fine core particle and process for producing the same |
US9833510B2 (en) * | 2007-06-12 | 2017-12-05 | Johnson & Johnson Consumer Inc. | Modified release solid or semi-solid dosage forms |
EP2217213B1 (en) | 2007-10-31 | 2017-05-24 | Johnson & Johnson Consumer Inc. | Orally disintegrative dosage form |
MX339852B (es) * | 2008-11-18 | 2016-06-15 | Ucb Pharma Sa | Formulaciones de liberacion prolongada que comprenden un derivado de 2-oxo-1-pirrolidina. |
US8858210B2 (en) | 2009-09-24 | 2014-10-14 | Mcneil-Ppc, Inc. | Manufacture of variable density dosage forms utilizing radiofrequency energy |
US8313768B2 (en) | 2009-09-24 | 2012-11-20 | Mcneil-Ppc, Inc. | Manufacture of tablet having immediate release region and sustained release region |
US8807979B2 (en) | 2009-09-24 | 2014-08-19 | Mcneil-Ppc, Inc. | Machine for the manufacture of dosage forms utilizing radiofrequency energy |
EP2488029B1 (en) | 2009-09-30 | 2016-03-23 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse |
SG174658A1 (en) * | 2010-04-01 | 2011-10-28 | Theravida Inc | Pharmaceutical formulations for the treatment of overactive bladder |
CN102641496A (zh) | 2011-02-16 | 2012-08-22 | 辛绍祺 | 高分子聚合物的新用途及其组成物 |
JP6068447B2 (ja) | 2011-05-10 | 2017-01-25 | セラヴィダ,インコーポレイテッド | 過活動膀胱の治療のためのソリフェナシンと唾液分泌刺激剤の組合せ |
CN102579367B (zh) * | 2012-03-23 | 2014-03-12 | 中国人民解放军军事医学科学院毒物药物研究所 | 托吡酯缓释药物组合物、其制备方法及用途 |
US9445971B2 (en) | 2012-05-01 | 2016-09-20 | Johnson & Johnson Consumer Inc. | Method of manufacturing solid dosage form |
US9233491B2 (en) | 2012-05-01 | 2016-01-12 | Johnson & Johnson Consumer Inc. | Machine for production of solid dosage forms |
US9511028B2 (en) | 2012-05-01 | 2016-12-06 | Johnson & Johnson Consumer Inc. | Orally disintegrating tablet |
EP3446685A1 (en) | 2012-11-30 | 2019-02-27 | Acura Pharmaceuticals, Inc. | Self-regulated release of active pharmaceutical ingredient |
JP6505721B2 (ja) | 2014-01-10 | 2019-04-24 | ジョンソン・アンド・ジョンソン・コンシューマー・インコーポレイテッド | 高周波及び損失性被覆粒子を使用した錠剤の製造プロセス |
WO2015145461A1 (en) | 2014-03-26 | 2015-10-01 | Sun Pharma Advanced Research Company Ltd. | Abuse deterrent immediate release biphasic matrix solid dosage form |
EP3157516A4 (en) | 2014-06-22 | 2017-12-13 | Dexcel Pharma Technologies Ltd. | Pharmaceutical compositions comprising ferric citrate and methods for the production thereof |
US10114116B2 (en) | 2014-08-19 | 2018-10-30 | Navico Holding As | Common burst for pulse compression radar |
US11103581B2 (en) | 2015-08-31 | 2021-08-31 | Acura Pharmaceuticals, Inc. | Methods and compositions for self-regulated release of active pharmaceutical ingredient |
BR112018014661A2 (pt) | 2016-01-20 | 2018-12-11 | Theravida Inc | composição e composição para uso |
US10493026B2 (en) | 2017-03-20 | 2019-12-03 | Johnson & Johnson Consumer Inc. | Process for making tablet using radiofrequency and lossy coated particles |
WO2018200857A1 (en) * | 2017-04-26 | 2018-11-01 | Cornell University | Grafted porous cyclodextrin polymeric material and methods of making and using same |
DE102019200138A1 (de) | 2019-01-08 | 2020-07-09 | Beiersdorf Ag | Zubereitung mit Vinylamine/N-vinylformamide Copolymer beschichteteten Cellulosepartikeln |
DE102019200135A1 (de) | 2019-01-08 | 2020-07-09 | Beiersdorf Ag | Zubereitung mit Vinylamine/N-vinylformamide Copolymer beschichteten Siliciumdioxidpartikeln |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4851226A (en) * | 1987-11-16 | 1989-07-25 | Mcneil Consumer Products Company | Chewable medicament tablet containing means for taste masking |
FR2624732B1 (fr) * | 1987-12-21 | 1991-02-15 | Synthelabo | Formulation pharmaceutique a liberation prolongee |
US5077051A (en) * | 1990-04-10 | 1991-12-31 | Warner-Lambert Company | Sustained release of active agents from bioadhesive microcapsules |
JP2542122B2 (ja) * | 1990-04-18 | 1996-10-09 | 旭化成工業株式会社 | 球状核、球形顆粒およびその製造方法 |
DE69111287T2 (de) * | 1990-04-18 | 1995-12-21 | Asahi Chemical Ind | Kugelförmige Keimkerne, kugelförmige Granulate sowie Verfahren zu deren Herstellung. |
JPH10182438A (ja) * | 1991-03-07 | 1998-07-07 | Takeda Chem Ind Ltd | 有核散剤 |
CA2062697C (en) * | 1991-03-22 | 1997-04-22 | Charles W. Connors, Jr. | Method and apparatus for manufacturing and repairing molten metal containment vessels |
JP2892858B2 (ja) * | 1991-05-15 | 1999-05-17 | 田辺製薬株式会社 | 放出制御製剤およびその製造法 |
CA2068402C (en) * | 1991-06-14 | 1998-09-22 | Michael R. Hoy | Taste mask coatings for preparation of chewable pharmaceutical tablets |
GB9114374D0 (en) * | 1991-07-03 | 1991-08-21 | Smithkline Beecham Plc | Novel process |
FR2682874B1 (fr) * | 1991-10-24 | 1993-12-10 | Rinrone Ets | Procede pour la preparation d'un extrait de principes actifs sous forme seche adsorbable et microgranules adsorbables ainsi obtenus. |
HU217629B (hu) * | 1991-12-12 | 2000-03-28 | Novartis Ag. | Eljárás fluvasztatint tartalmazó stabilizált gyógyszerkészítmények előállítására |
JPH05213740A (ja) * | 1992-02-04 | 1993-08-24 | Dainippon Pharmaceut Co Ltd | 粒子製剤 |
US5429825A (en) * | 1992-06-26 | 1995-07-04 | Mcneil-Ppc, Inc. | Rotomelt granulation |
JPH08502980A (ja) * | 1992-11-05 | 1996-04-02 | メルク エンド カンパニー インコーポレーテッド | 薬剤配送装置 |
EP0706794B1 (en) * | 1994-10-14 | 2001-12-12 | Japan Energy Corporation | Anti-aids pharmaceutical preparations and processes for the production thereof |
US5529783A (en) * | 1994-12-19 | 1996-06-25 | Mcneil-Ppc, Inc. | Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan |
US5547948A (en) * | 1995-01-17 | 1996-08-20 | American Home Products Corporation | Controlled release of steroids from sugar coatings |
US5573783A (en) * | 1995-02-13 | 1996-11-12 | Nano Systems L.L.C. | Redispersible nanoparticulate film matrices with protective overcoats |
TW289733B (en) * | 1995-05-05 | 1996-11-01 | Hua Shin Chemical Pharmaceutical Works Co Ltd | Process for preparing round pellets of Omeprazole for oral administration |
JP3833314B2 (ja) * | 1995-09-08 | 2006-10-11 | 武田薬品工業株式会社 | 発泡性組成物およびその製造方法 |
US5780055A (en) * | 1996-09-06 | 1998-07-14 | University Of Maryland, Baltimore | Cushioning beads and tablet comprising the same capable of forming a suspension |
US5997905A (en) * | 1998-09-04 | 1999-12-07 | Mcneil-Ppc | Preparation of pharmaceutically active particles |
-
1998
- 1998-09-04 US US09/148,251 patent/US5997905A/en not_active Expired - Lifetime
-
1999
- 1999-09-02 AU AU47350/99A patent/AU773833B2/en not_active Ceased
- 1999-09-02 BR BR9904039-5A patent/BR9904039A/pt not_active Application Discontinuation
- 1999-09-03 CA CA002281420A patent/CA2281420C/en not_active Expired - Fee Related
- 1999-09-03 JP JP11250489A patent/JP2000109426A/ja active Pending
- 1999-09-03 DE DE69921941T patent/DE69921941T2/de not_active Expired - Lifetime
- 1999-09-03 CN CNB991186117A patent/CN1151844C/zh not_active Expired - Fee Related
- 1999-09-03 ES ES99307051T patent/ES2233003T3/es not_active Expired - Lifetime
- 1999-09-03 EP EP99307051A patent/EP1000615B1/en not_active Expired - Lifetime
- 1999-11-02 US US09/431,899 patent/US6149943A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6149943A (en) | 2000-11-21 |
CN1151844C (zh) | 2004-06-02 |
ES2233003T3 (es) | 2005-06-01 |
DE69921941T2 (de) | 2005-12-01 |
EP1000615B1 (en) | 2004-11-17 |
US5997905A (en) | 1999-12-07 |
JP2000109426A (ja) | 2000-04-18 |
CN1249950A (zh) | 2000-04-12 |
AU4735099A (en) | 2000-03-16 |
AU773833B2 (en) | 2004-06-10 |
CA2281420A1 (en) | 2000-03-04 |
DE69921941D1 (de) | 2004-12-23 |
EP1000615A2 (en) | 2000-05-17 |
EP1000615A3 (en) | 2000-05-31 |
CA2281420C (en) | 2008-11-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9904039A (pt) | Preparação de partìculas farmaceuticamente ativas | |
BR9807368A (pt) | Comprimidos de oxacarvazepina revestidos com pelìcula | |
ATE239454T1 (de) | Orale morphinzubereitung in teilchenform | |
BR9806174A (pt) | Péletes tendo um núcleo revestido com um antifúngico e um polìmero | |
KR910004180A (ko) | 저작성 약제학적 정제를 제조하기 위한 회전과립화 공정 및 맛을 은폐하기 위한 피복공정 | |
BR9608208A (pt) | Composição de revestimento de pó para revestimento eletrotático de substrato farmacêuticos | |
CA2124012A1 (fr) | Formulation de diltiazem a liberation prolongee | |
BR9711378A (pt) | Forma gal-ncia com libera-Æo prolongada | |
EP1504758A3 (en) | Controlled-release formulations coated with aqueous dispersions of ethylcellulose | |
AU2088092A (en) | Pharmaceutical spheroid formulation | |
ATE228825T1 (de) | Orale dosierungsformen mit pulverschicht | |
BR9806238A (pt) | Partìculas revestidas: processos de obtenção e uso | |
CA2315975A1 (en) | Phospholipid-coated microcrystals for the sustained release of pharmacologically active compounds and methods of their manufacture and use | |
BR0202491A (pt) | Forma de dosagem de núcleo macio, de revestimento frágil | |
BR9714253A (pt) | Forma de dosagem farmacêutica de libertação rápida e dissimuladora do sabor | |
DK0946145T3 (da) | Antitussive lægemidler afgivet af ionbytterharpikser | |
BR9813179A (pt) | Formulação de liberação prolongada | |
HK1070821A1 (en) | Extended release venlafaxine tablet formulation | |
BR0112839A (pt) | Composição de eletriptano em partìculas | |
AR040461A1 (es) | Microcapsulas para la liberacion retardada y controlada de perindopril | |
WO1999042087A3 (en) | Controlled release potassium chloride pellet based pharmaceutical compositions having a high active ingredient content | |
BR9909963A (pt) | Péletes possuindo um núcleo revestido com um agente redutor de lipìdeos e um polìmero | |
MX9203020A (es) | Microesferas de diltiazem y composiciones farmaceuticas de liberacion prolongada que las contienen. | |
KR970703774A (ko) | 활성물질 방출이 지연된 카바마제핀 약제(Carbamazepine medicament with retarded active substance release) | |
BR0109640A (pt) | Forma de droga multiparticulada compreendendo pelo menos duas formas de pélete diferentemente revestidas |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
HHB | Publication of an application: rectification | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O , 13 E 25 DA LPI |
|
B15K | Others concerning applications: alteration of classification |
Free format text: PARA:INT.CI A61K 9/24; A61K 9/32; A61K 9/16; A61K 31/137; A61K 31/165; A61K 31/485; A61K 47/38; A61P 11/00 Ipc: A61K 9/24 (2010.01), A61K 9/32 (2010.01), A61K 9/1 |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |