BR9909963A - Péletes possuindo um núcleo revestido com um agente redutor de lipìdeos e um polìmero - Google Patents

Péletes possuindo um núcleo revestido com um agente redutor de lipìdeos e um polìmero

Info

Publication number
BR9909963A
BR9909963A BR9909963-2A BR9909963A BR9909963A BR 9909963 A BR9909963 A BR 9909963A BR 9909963 A BR9909963 A BR 9909963A BR 9909963 A BR9909963 A BR 9909963A
Authority
BR
Brazil
Prior art keywords
pellets
reducing agent
polymer
lipid
core coated
Prior art date
Application number
BR9909963-2A
Other languages
English (en)
Inventor
Valentin Florent Victor Conde
Paul Marie Victor Gilis
Peter Puttemann
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of BR9909963A publication Critical patent/BR9909963A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Patente de Invenção: <B>"PéLETES POSSUINDO UM NúCLEO REVESTIDO COM UM AGENTE REDUTOR DE LIPìDEOS E UM POLìMERO"<D>. A presente invenção se refere a péletes compreendendo esferas de açúcar 250-1180 <109>m (16-60 mesh), uma película de revestimento de um polímero solúvel em água e um agente redutor de lipídeos moderadamente solúvel e uma camada de revestimento-vedação; formas de dosagem farmacêuticas compreendendo os péletes e um processo para preparação dos péletes.
BR9909963-2A 1998-04-27 1999-04-20 Péletes possuindo um núcleo revestido com um agente redutor de lipìdeos e um polìmero BR9909963A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98201331 1998-04-27
PCT/EP1999/002768 WO1999055313A1 (en) 1998-04-27 1999-04-20 Pellets having a core coated with a lipid lowering agent and a polymer

Publications (1)

Publication Number Publication Date
BR9909963A true BR9909963A (pt) 2000-12-26

Family

ID=8233644

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9909963-2A BR9909963A (pt) 1998-04-27 1999-04-20 Péletes possuindo um núcleo revestido com um agente redutor de lipìdeos e um polìmero

Country Status (14)

Country Link
EP (1) EP1073424A1 (pt)
JP (1) JP2002544118A (pt)
KR (1) KR20010041460A (pt)
CN (1) CN1308523A (pt)
AU (1) AU3710099A (pt)
BG (1) BG104757A (pt)
BR (1) BR9909963A (pt)
CA (1) CA2328970A1 (pt)
EE (1) EE200000796A (pt)
HU (1) HUP0102052A3 (pt)
NO (1) NO20005426L (pt)
PL (1) PL358909A1 (pt)
SK (1) SK15252000A3 (pt)
WO (1) WO1999055313A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1413624B1 (en) * 2002-10-22 2006-03-08 Rohm and Haas Company Tablet coating
EP1708684A2 (en) 2003-09-26 2006-10-11 Alza Corporation Drug coating providing high drug loading and methods for providing the same
US20080234291A1 (en) * 2004-01-21 2008-09-25 Marc Karel Jozef Francois Mitratapide Oral Solution
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
FR2897267A1 (fr) * 2006-02-16 2007-08-17 Flamel Technologies Sa Formes pharmaceutiques multimicroparticulaires pour administration per os
HRP20220331T1 (hr) 2018-03-08 2022-05-13 Incyte Corporation Spojevi aminopirazin diola kao inhibitori pi3k-y
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK281908B6 (sk) * 1994-10-27 2001-09-11 Janssen Pharmaceutica N. V. Heteroarylsubstituované deriváty 1,3-dioxolan-4-ylmetoxyfenyl-1- piperazinylfenyl-2,4-dihydro-2-alkyl-3h-1,2,4-triazol-3-ónu, spôsob a medziprodukty na ich výrobu a farmaceutické prostriedky

Also Published As

Publication number Publication date
NO20005426D0 (no) 2000-10-27
EE200000796A (et) 2002-06-17
CA2328970A1 (en) 1999-11-04
AU3710099A (en) 1999-11-16
BG104757A (en) 2001-05-31
SK15252000A3 (sk) 2001-10-08
HUP0102052A2 (hu) 2002-05-29
HUP0102052A3 (en) 2002-10-28
JP2002544118A (ja) 2002-12-24
EP1073424A1 (en) 2001-02-07
PL358909A1 (en) 2004-08-23
NO20005426L (no) 2000-10-27
KR20010041460A (ko) 2001-05-25
CN1308523A (zh) 2001-08-15
WO1999055313A1 (en) 1999-11-04

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]