BRPI9509286B8 - microcápsulas medicamentosas e/ou nutricionais para administração per si. - Google Patents

microcápsulas medicamentosas e/ou nutricionais para administração per si. Download PDF

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Publication number
BRPI9509286B8
BRPI9509286B8 BRPI9509286A BRPI9509286A BRPI9509286B8 BR PI9509286 B8 BRPI9509286 B8 BR PI9509286B8 BR PI9509286 A BRPI9509286 A BR PI9509286A BR PI9509286 A BRPI9509286 A BR PI9509286A BR PI9509286 B8 BRPI9509286 B8 BR PI9509286B8
Authority
BR
Brazil
Prior art keywords
microcapsules
nutritional
time
administration per
medicated
Prior art date
Application number
BRPI9509286A
Other languages
English (en)
Inventor
Soula Gérard
Selles Jean-Philippe
Autant Pierre
Original Assignee
Flamel Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9468196&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI9509286(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Flamel Tech filed Critical Flamel Tech
Publication of BRPI9509286B8 publication Critical patent/BRPI9509286B8/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

patente de invenção para "microcápsulas medicamentosas e/ou nutricionais para administração per si". a presente invenção se refere a microcápsulas para administração per si dos princípios ativos medicamentosos e/ou nutricionais (pa), cujo tamanho é inferior ou igual à 1000 µm. estas microcápsulas são constituídas por duas partículas que sáo revestidas por um material de revestimento constituído por uma mistura de um derivado polimérico filmógeno, de um agente plastificante hidrófobo, de um agente tensoativo e/ou lubrificante e de um polímero azoto. estas microcápsulas são igualmente caracterizadas pela sua capacidade de permaneces por longo tempo (pelo menos cinco horas) dentro do intestino delgado e a permitir, durante o tempo de residência, à absorção do ap durante um período de tempo superior ao tempo do trânsito natural no intestino delgado. a invenção se refere também ao processo de obtenção das ditas microcápsulas e sua aplicação em galênico.
BRPI9509286A 1994-10-18 1995-10-18 microcápsulas medicamentosas e/ou nutricionais para administração per si. BRPI9509286B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9412759A FR2725623A1 (fr) 1994-10-18 1994-10-18 Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os
PCT/FR1995/001369 WO1996011675A2 (fr) 1994-10-18 1995-10-18 Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os

Publications (1)

Publication Number Publication Date
BRPI9509286B8 true BRPI9509286B8 (pt) 2019-12-17

Family

ID=9468196

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI9509286A BRPI9509286B8 (pt) 1994-10-18 1995-10-18 microcápsulas medicamentosas e/ou nutricionais para administração per si.
BR9509286A BR9509286A (pt) 1994-10-18 1995-10-18 Microcápsulas medicamentosas e/ou nutricionais para administração per si

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR9509286A BR9509286A (pt) 1994-10-18 1995-10-18 Microcápsulas medicamentosas e/ou nutricionais para administração per si

Country Status (14)

Country Link
US (1) US6022562A (pt)
EP (1) EP0709087B1 (pt)
JP (1) JP4053589B2 (pt)
AR (1) AR022930A2 (pt)
AT (1) ATE188117T1 (pt)
AU (1) AU3807795A (pt)
BR (2) BRPI9509286B8 (pt)
CA (1) CA2160762C (pt)
DE (1) DE69514192T2 (pt)
ES (1) ES2140641T3 (pt)
FR (1) FR2725623A1 (pt)
IL (1) IL115646A (pt)
WO (1) WO1996011675A2 (pt)
ZA (1) ZA958762B (pt)

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EP0709087B1 (fr) 1999-12-29
AR022930A2 (es) 2002-09-04
US6022562A (en) 2000-02-08
JPH10509427A (ja) 1998-09-14
ATE188117T1 (de) 2000-01-15
DE69514192D1 (de) 2000-02-03
IL115646A (en) 2000-07-16
CA2160762A1 (fr) 1996-04-19
WO1996011675A3 (fr) 1996-06-20
DE69514192T2 (de) 2000-07-13
ZA958762B (en) 1996-05-09
EP0709087A1 (fr) 1996-05-01
IL115646A0 (en) 1996-01-19
WO1996011675A2 (fr) 1996-04-25
AU3807795A (en) 1996-05-06
FR2725623B1 (pt) 1997-02-21
BR9509286A (pt) 1997-10-14
CA2160762C (fr) 2004-12-21
ES2140641T3 (es) 2000-03-01
JP4053589B2 (ja) 2008-02-27
FR2725623A1 (fr) 1996-04-19

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