FR2843880B1 - Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline - Google Patents

Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline

Info

Publication number
FR2843880B1
FR2843880B1 FR0210846A FR0210846A FR2843880B1 FR 2843880 B1 FR2843880 B1 FR 2843880B1 FR 0210846 A FR0210846 A FR 0210846A FR 0210846 A FR0210846 A FR 0210846A FR 2843880 B1 FR2843880 B1 FR 2843880B1
Authority
FR
France
Prior art keywords
microcapsules
pharmaceutical formulation
aqueous suspension
oral pharmaceutical
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0210846A
Other languages
English (en)
Other versions
FR2843880A1 (fr
Inventor
Catherine Castan
Florence Guimberteau
Remi Meyrueix
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flamel Technologies SA
Original Assignee
Flamel Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0210846A priority Critical patent/FR2843880B1/fr
Application filed by Flamel Technologies SA filed Critical Flamel Technologies SA
Priority to US10/510,621 priority patent/US7910133B2/en
Priority to PCT/FR2003/001095 priority patent/WO2003084517A2/fr
Priority to JP2003581757A priority patent/JP4698950B2/ja
Priority to BR0309093-0A priority patent/BR0309093A/pt
Priority to DE60323474T priority patent/DE60323474D1/de
Priority to IL16422103A priority patent/IL164221A0/xx
Priority to MXPA04009979A priority patent/MXPA04009979A/es
Priority to CA002480824A priority patent/CA2480824A1/fr
Priority to ES03745831T priority patent/ES2314227T7/es
Priority to KR10-2004-7016060A priority patent/KR20050005437A/ko
Priority to PT03745831T priority patent/PT1492531E/pt
Priority to AT03745831T priority patent/ATE407674T1/de
Priority to CN03810527A priority patent/CN100577164C/zh
Priority to EP03745831A priority patent/EP1492531B3/fr
Priority to AU2003246791A priority patent/AU2003246791A1/en
Publication of FR2843880A1 publication Critical patent/FR2843880A1/fr
Application granted granted Critical
Publication of FR2843880B1 publication Critical patent/FR2843880B1/fr
Priority to US13/024,835 priority patent/US20110129539A1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0210846A 2002-04-09 2002-09-02 Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline Expired - Fee Related FR2843880B1 (fr)

Priority Applications (17)

Application Number Priority Date Filing Date Title
FR0210846A FR2843880B1 (fr) 2002-09-02 2002-09-02 Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline
AT03745831T ATE407674T1 (de) 2002-04-09 2003-04-07 Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin
JP2003581757A JP4698950B2 (ja) 2002-04-09 2003-04-07 アモキシシリンの改変された放出のための、マイクロカプセルの水性懸濁液形態での経口医薬品製剤
BR0309093-0A BR0309093A (pt) 2002-04-09 2003-04-07 Formulação farmacêutica oral sob a forma de suspensão aquosa de microcápsulas permitindo a liberação modificada de amoxicilina
DE60323474T DE60323474D1 (de) 2002-04-09 2003-04-07 Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin
IL16422103A IL164221A0 (en) 2002-04-09 2003-04-07 Oral pharmaceutical formulation in the form of aqueous suspension of microcapsules for modified release of amoxicillim
MXPA04009979A MXPA04009979A (es) 2002-04-09 2003-04-07 Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de amoxicilina.
CA002480824A CA2480824A1 (fr) 2002-04-09 2003-04-07 Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline
US10/510,621 US7910133B2 (en) 2002-04-09 2003-04-07 Oral pharmaceutical formulation in the form of aqueous suspension of microcapsules for modified release of amoxicillin
KR10-2004-7016060A KR20050005437A (ko) 2002-04-09 2003-04-07 아목시실린의 변형 방출을 위한 마이크로캡슐 수성 현탁액형태의 경구 제약학적 제제
PT03745831T PT1492531E (pt) 2002-04-09 2003-04-07 Formulação farmacêutica oral sob a forma de suspensão aquosa de microcápsulas que permite a libertação modificada de amoxicilina
PCT/FR2003/001095 WO2003084517A2 (fr) 2002-04-09 2003-04-07 Suspension orale de microcapsules d’amoxicilline
CN03810527A CN100577164C (zh) 2002-04-09 2003-04-07 可改进释放阿莫西林的微囊含水混悬液形式的口服药物制剂
EP03745831A EP1492531B3 (fr) 2002-04-09 2003-04-07 Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiée d'amoxicilline
AU2003246791A AU2003246791A1 (en) 2002-04-09 2003-04-07 Oral suspension of amoxicillin capsules
ES03745831T ES2314227T7 (es) 2002-04-09 2003-04-07 Formulacion farmaceutica oral en forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de amoxilicina.
US13/024,835 US20110129539A1 (en) 2002-04-09 2011-02-10 Oral pharmaceutical formulation in the form of an aqueous suspension of microcapsules for modified release of amoxicillin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0210846A FR2843880B1 (fr) 2002-09-02 2002-09-02 Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline

Publications (2)

Publication Number Publication Date
FR2843880A1 FR2843880A1 (fr) 2004-03-05
FR2843880B1 true FR2843880B1 (fr) 2006-06-02

Family

ID=31503047

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0210846A Expired - Fee Related FR2843880B1 (fr) 2002-04-09 2002-09-02 Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline

Country Status (1)

Country Link
FR (1) FR2843880B1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113116860B (zh) * 2021-04-22 2022-11-25 海南通用三洋药业有限公司 一种阿莫西林胶囊及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2085342A1 (fr) * 1990-06-14 1991-12-15 Milton R. Kaplan Suspension aqueuse stable de medicament
FR2725623A1 (fr) * 1994-10-18 1996-04-19 Flamel Tech Sa Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os
CA2435305A1 (fr) * 2001-01-18 2002-07-25 Natco Pharma Limited Composition pharmaceutique a liberation lente contenant des antibiotiques .beta.-lactame a efficacite therapeutique amelioree

Also Published As

Publication number Publication date
FR2843880A1 (fr) 2004-03-05

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Effective date: 20090529